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The map label for this gene is xseA [H]

Identifier: 93005919

GI number: 93005919

Start: 1315077

End: 1316621

Strand: Reverse

Name: xseA [H]

Synonym: Pcryo_1091

Alternate gene names: 93005919

Gene position: 1316621-1315077 (Counterclockwise)

Preceding gene: 93005920

Following gene: 93005918

Centisome position: 43.03

GC content: 44.85

Gene sequence:

>1545_bases
ATGCGCAAACCCAACCTGTCAAATACCAAGCAAATTAAAGTATTAGCGCCTGCCAAAGATTTAGCGACCTTGGAGGCGGA
ATTGGCAGAACAAGAAAACAGTGTAGAAAATAACTTAGAAGATACTGTCCTGCGCCTTAGTGATTACTTATCAGCGGTCG
ATATGGTGATCAAGCAAACTTTTAATCACCGTGTTTGGGTCAAAGCTGAGATACGAAATTTATCTAGCAAAGGTGGGCAT
TATTATTTTGAATTGGCAGAAAAAGATGACGACGGCAAAGTCATTGCCAGCTGCCGTGGTAACCTTTGGCGCTTTAAAGC
GGCGCGGGTTTTAGCCAAGTTTGAGCGCGCAACGGGTATGCCACTGGATCGCGATTTGACGGTTTTATTAAAGGTATCGG
CAGGTTTCCATGCGCAATACGGCTTCTCTCTCACCATTGAAGATATTGACCCAAGCTATACGTTAGGCGATTTAGCGCGT
CAATATGCTGAGATGGTTGACCGCTTGGCAGGTGAAGGATTATTAAACCTGAATCAGCAGTTGCCAACTCCGTTTGATAT
CGAGCAGGTGTTGGTCATCGCTCCTGAAAAAGCCGCAGGGCTAGGCGATTTTCAAGCGGACGCCAACAGACTCGCTAGTA
CAGGCGCTTGTCATTTCCATTATCATAACGCCACTTTTCAAGGTAATCATGCCCCAGCGGAGATTCGTCAAGCAATCATC
AGTGCTCAGCAGCAATTTGAAAATACTTATCAGCGCCTTCCAGATTTATTAGTAATTATCCGTGGTGGCGGCGCTGTTGG
TGATTTGGCTTACCTTAATGATTATGAGCTTGCTGCTTTAGTCGCTGAGCAACCTGTCCCTGTTTGGGTTGGGATTGGTC
ATGAGCGTGACAAAGTTATCTTAGATGAAGTGGCTCATACTAGCTTTGATACGCCATCAAAAGTCATTGCGGCTATCATG
GCACATTTAGCACAGCTGGTCACTCAGACACTGCAATATCAAATGCAAATCAAACAAGCAGCGCAGCGTCAATTAAATAC
CGCTGAACAACAAACTGCGCGCCAATTGAGCCAAATACAATCGCAAACCATTGGTCAATTAACGGCACTACAAAAAGACA
GTGCTTATGCGTGGCGTAGTATCCAACAAAGTGCACATCGTCAAGTGAAACAAGCTGCCAGACAAGCAAGCGAGCTGCAT
ATACAGACTCAAGCCTCTGCTTATCAACAACTTTCACTCGCCTCTACTTATAGTAAAAATCATCAGAAAATTATTATGCA
AAGTGCTCAGCAGCAGTTAATACAAGCGCAGCGTGATAGCGCACATCTGCGTGATATTGTACTCTTGCATCGACCGTCTC
GCGTGCTTAAGCAAGGCTATAGCATGCTGACTGATGAACAGGACCAACGAATACTGACCAGTAGCAACCAGCTTTACCCG
GAGCAGACCATTCATATCGTCCTAAAAGACGGTAAAGCAAAAGCACAAATCATTGACATTAAAATGGATAAGAAGCCCAC
AGAATTTACAGAAGCTTCCACTTAA

Upstream 100 bases:

>100_bases
CTTTGCTTTTTGTGTAGAGGCTTTTAGGTTAAACTACCTTATCTTATCTTTTACCTCACCTAGCTGGTCTCTAAGCCCTC
ACTATCTTTGGTCTATTATT

Downstream 100 bases:

>100_bases
CCCCATAATAATATTTCACGATTATTTATTACTTTTACTTTAGATATTAGGAAACCTTATGACTACCCCTATACGTAAAC
GCAAAAAAGCCGCCCCAAAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MRKPNLSNTKQIKVLAPAKDLATLEAELAEQENSVENNLEDTVLRLSDYLSAVDMVIKQTFNHRVWVKAEIRNLSSKGGH
YYFELAEKDDDGKVIASCRGNLWRFKAARVLAKFERATGMPLDRDLTVLLKVSAGFHAQYGFSLTIEDIDPSYTLGDLAR
QYAEMVDRLAGEGLLNLNQQLPTPFDIEQVLVIAPEKAAGLGDFQADANRLASTGACHFHYHNATFQGNHAPAEIRQAII
SAQQQFENTYQRLPDLLVIIRGGGAVGDLAYLNDYELAALVAEQPVPVWVGIGHERDKVILDEVAHTSFDTPSKVIAAIM
AHLAQLVTQTLQYQMQIKQAAQRQLNTAEQQTARQLSQIQSQTIGQLTALQKDSAYAWRSIQQSAHRQVKQAARQASELH
IQTQASAYQQLSLASTYSKNHQKIIMQSAQQQLIQAQRDSAHLRDIVLLHRPSRVLKQGYSMLTDEQDQRILTSSNQLYP
EQTIHIVLKDGKAKAQIIDIKMDKKPTEFTEAST

Sequences:

>Translated_514_residues
MRKPNLSNTKQIKVLAPAKDLATLEAELAEQENSVENNLEDTVLRLSDYLSAVDMVIKQTFNHRVWVKAEIRNLSSKGGH
YYFELAEKDDDGKVIASCRGNLWRFKAARVLAKFERATGMPLDRDLTVLLKVSAGFHAQYGFSLTIEDIDPSYTLGDLAR
QYAEMVDRLAGEGLLNLNQQLPTPFDIEQVLVIAPEKAAGLGDFQADANRLASTGACHFHYHNATFQGNHAPAEIRQAII
SAQQQFENTYQRLPDLLVIIRGGGAVGDLAYLNDYELAALVAEQPVPVWVGIGHERDKVILDEVAHTSFDTPSKVIAAIM
AHLAQLVTQTLQYQMQIKQAAQRQLNTAEQQTARQLSQIQSQTIGQLTALQKDSAYAWRSIQQSAHRQVKQAARQASELH
IQTQASAYQQLSLASTYSKNHQKIIMQSAQQQLIQAQRDSAHLRDIVLLHRPSRVLKQGYSMLTDEQDQRILTSSNQLYP
EQTIHIVLKDGKAKAQIIDIKMDKKPTEFTEAST
>Mature_514_residues
MRKPNLSNTKQIKVLAPAKDLATLEAELAEQENSVENNLEDTVLRLSDYLSAVDMVIKQTFNHRVWVKAEIRNLSSKGGH
YYFELAEKDDDGKVIASCRGNLWRFKAARVLAKFERATGMPLDRDLTVLLKVSAGFHAQYGFSLTIEDIDPSYTLGDLAR
QYAEMVDRLAGEGLLNLNQQLPTPFDIEQVLVIAPEKAAGLGDFQADANRLASTGACHFHYHNATFQGNHAPAEIRQAII
SAQQQFENTYQRLPDLLVIIRGGGAVGDLAYLNDYELAALVAEQPVPVWVGIGHERDKVILDEVAHTSFDTPSKVIAAIM
AHLAQLVTQTLQYQMQIKQAAQRQLNTAEQQTARQLSQIQSQTIGQLTALQKDSAYAWRSIQQSAHRQVKQAARQASELH
IQTQASAYQQLSLASTYSKNHQKIIMQSAQQQLIQAQRDSAHLRDIVLLHRPSRVLKQGYSMLTDEQDQRILTSSNQLYP
EQTIHIVLKDGKAKAQIIDIKMDKKPTEFTEAST

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=342, Percent_Identity=26.6081871345029, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 57487; Mature: 57487

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKPNLSNTKQIKVLAPAKDLATLEAELAEQENSVENNLEDTVLRLSDYLSAVDMVIKQT
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FNHRVWVKAEIRNLSSKGGHYYFELAEKDDDGKVIASCRGNLWRFKAARVLAKFERATGM
CCCEEEEEEHHHCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
PLDRDLTVLLKVSAGFHAQYGFSLTIEDIDPSYTLGDLARQYAEMVDRLAGEGLLNLNQQ
CCCCCCEEEEEECCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHC
LPTPFDIEQVLVIAPEKAAGLGDFQADANRLASTGACHFHYHNATFQGNHAPAEIRQAII
CCCCCCCCEEEEECCCHHCCCCCCHHHHHHHHCCCEEEEEEECCEECCCCCHHHHHHHHH
SAQQQFENTYQRLPDLLVIIRGGGAVGDLAYLNDYELAALVAEQPVPVWVGIGHERDKVI
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECCCCCCHHH
LDEVAHTSFDTPSKVIAAIMAHLAQLVTQTLQYQMQIKQAAQRQLNTAEQQTARQLSQIQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQTIGQLTALQKDSAYAWRSIQQSAHRQVKQAARQASELHIQTQASAYQQLSLASTYSKN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCC
HQKIIMQSAQQQLIQAQRDSAHLRDIVLLHRPSRVLKQGYSMLTDEQDQRILTSSNQLYP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHCCCCCCC
EQTIHIVLKDGKAKAQIIDIKMDKKPTEFTEAST
CCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRKPNLSNTKQIKVLAPAKDLATLEAELAEQENSVENNLEDTVLRLSDYLSAVDMVIKQT
CCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
FNHRVWVKAEIRNLSSKGGHYYFELAEKDDDGKVIASCRGNLWRFKAARVLAKFERATGM
CCCEEEEEEHHHCCCCCCCEEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCC
PLDRDLTVLLKVSAGFHAQYGFSLTIEDIDPSYTLGDLARQYAEMVDRLAGEGLLNLNQQ
CCCCCCEEEEEECCCCEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHC
LPTPFDIEQVLVIAPEKAAGLGDFQADANRLASTGACHFHYHNATFQGNHAPAEIRQAII
CCCCCCCCEEEEECCCHHCCCCCCHHHHHHHHCCCEEEEEEECCEECCCCCHHHHHHHHH
SAQQQFENTYQRLPDLLVIIRGGGAVGDLAYLNDYELAALVAEQPVPVWVGIGHERDKVI
HHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCCCHHHHHHHHCCCCEEEEECCCCCCHHH
LDEVAHTSFDTPSKVIAAIMAHLAQLVTQTLQYQMQIKQAAQRQLNTAEQQTARQLSQIQ
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQTIGQLTALQKDSAYAWRSIQQSAHRQVKQAARQASELHIQTQASAYQQLSLASTYSKN
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHCC
HQKIIMQSAQQQLIQAQRDSAHLRDIVLLHRPSRVLKQGYSMLTDEQDQRILTSSNQLYP
HHHHHHHHHHHHHHHHHHCHHHHHHHHHEECCHHHHHHHHHHHCCCCCCHHHHCCCCCCC
EQTIHIVLKDGKAKAQIIDIKMDKKPTEFTEAST
CCEEEEEEECCCCCEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]