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The map label for this gene is ppa [H]

Identifier: 93005911

GI number: 93005911

Start: 1303916

End: 1304446

Strand: Reverse

Name: ppa [H]

Synonym: Pcryo_1083

Alternate gene names: 93005911

Gene position: 1304446-1303916 (Counterclockwise)

Preceding gene: 93005912

Following gene: 93005910

Centisome position: 42.63

GC content: 42.94

Gene sequence:

>531_bases
ATGGCAGATTTTAACAAAATTTTGGACGCAGGCGATGTTGAGGGCGGCATTATTAATGTCGTAGTAGAAATCCCAGCTGG
TAGTAGCCATAAAATTGAGTGGAATCGCGAGTTGGCCGTATTTGAGCTTGATCGTGTTGACCCACAGATTTTTGCCAAGC
CTTGCAACTATGGTTTTATCCCACAAACTCTTGATGAAGATGGCGACGAGTTAGATGCGCTTATCATCACAGAACAGCCT
TTACCGACTGGTATTTTCTTAAAAGCGAAAGTCATCGGTGTGATGAAGTTCGTTGATGATGGCGAAGTCGATGACAAAAT
AGTTGTCGTACCTGCTGACGACCGTGATACAGGCAATGCTTATAACAGTCTAGCGGACTTACCAAAGCAGCTGATCAATC
AGCTAGAATTCCATTTCAGTCACTATAAAGACCTCAAAAAAGCAGGTACAACGGTGGTTGAATCTTGGGGTGACGTAGAA
GAAGCCAAAGAAGTCATTAAAGAGTCTATCCAACGCTGGAAAGATCTATAA

Upstream 100 bases:

>100_bases
ATCGCACACGGTACAAATTGGGCGCAGTAACAAACCTTATACGCCGACTTTAACCCTTTACGATTCAAACATTCATAACA
AAAGCAAATTGGAGTATTTT

Downstream 100 bases:

>100_bases
ATTAAAATGAAATAAAATTGATAACAGTACCGCAGATATGATGATAACTGCGGTATTTTTTTGCTTGAATTTTGACTGTA
CAACAAGGTTATAATACCCC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MADFNKILDAGDVEGGIINVVVEIPAGSSHKIEWNRELAVFELDRVDPQIFAKPCNYGFIPQTLDEDGDELDALIITEQP
LPTGIFLKAKVIGVMKFVDDGEVDDKIVVVPADDRDTGNAYNSLADLPKQLINQLEFHFSHYKDLKKAGTTVVESWGDVE
EAKEVIKESIQRWKDL

Sequences:

>Translated_176_residues
MADFNKILDAGDVEGGIINVVVEIPAGSSHKIEWNRELAVFELDRVDPQIFAKPCNYGFIPQTLDEDGDELDALIITEQP
LPTGIFLKAKVIGVMKFVDDGEVDDKIVVVPADDRDTGNAYNSLADLPKQLINQLEFHFSHYKDLKKAGTTVVESWGDVE
EAKEVIKESIQRWKDL
>Mature_175_residues
ADFNKILDAGDVEGGIINVVVEIPAGSSHKIEWNRELAVFELDRVDPQIFAKPCNYGFIPQTLDEDGDELDALIITEQPL
PTGIFLKAKVIGVMKFVDDGEVDDKIVVVPADDRDTGNAYNSLADLPKQLINQLEFHFSHYKDLKKAGTTVVESWGDVEE
AKEVIKESIQRWKDL

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=162, Percent_Identity=37.6543209876543, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19656; Mature: 19525

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFNKILDAGDVEGGIINVVVEIPAGSSHKIEWNRELAVFELDRVDPQIFAKPCNYGFI
CCCHHHHHCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEEECCCCHHHEECCCCCCCC
PQTLDEDGDELDALIITEQPLPTGIFLKAKVIGVMKFVDDGEVDDKIVVVPADDRDTGNA
CCCCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHH
YNSLADLPKQLINQLEFHFSHYKDLKKAGTTVVESWGDVEEAKEVIKESIQRWKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADFNKILDAGDVEGGIINVVVEIPAGSSHKIEWNRELAVFELDRVDPQIFAKPCNYGFI
CCHHHHHCCCCCCCCEEEEEEECCCCCCCEEEECCCEEEEEECCCCHHHEECCCCCCCC
PQTLDEDGDELDALIITEQPLPTGIFLKAKVIGVMKFVDDGEVDDKIVVVPADDRDTGNA
CCCCCCCCCCEEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHH
YNSLADLPKQLINQLEFHFSHYKDLKKAGTTVVESWGDVEEAKEVIKESIQRWKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]