Click here to switch to the map view.

The map label for this gene is fabG [H]

Identifier: 93005897

GI number: 93005897

Start: 1286503

End: 1287903

Strand: Direct

Name: fabG [H]

Synonym: Pcryo_1069

Alternate gene names: 93005897

Gene position: 1286503-1287903 (Clockwise)

Preceding gene: 93005894

Following gene: 93005898

Centisome position: 42.04

GC content: 45.9

Gene sequence:

>1401_bases
ATGTCAGACCGTTATGGTGATTTTGTTCAGTCGTCTATTGGTAAAAAGGTCGCAAAGAATTTGGGCTTACCAATGCCAGT
AGATCTTGACCGTTTTGATAGTGGTCAACCTTTGGTACGTGGCAGCGTGCTGGTTGGTCGTGCTAATGGTGGCGATAACG
CAGTTAGTGCGTCAGTGGCTCGTATTTTGTCAGAGCTGCATACGGAAATCTTTGTAAATAGTGGTGATGACGTAAAAGAT
ACCCTGTCGGATGCAGGCGTCAAAGCCAAAGCCAATACTGGCAGTGATGATAAGTTTAAAGTTTTATTGTTTGATGCCAG
CAATATTAGCAATGCTGAAGAGCTCAAACAAGTGTACGAGTTCTTTCATAGCGTTGCGCGCCGTGTCGAAAAATCAGGTC
GAGTGATCGTCATTGGTCGTCCACCAGAAGCGTTGACTGATATCGAAGCCGCATTGGCGCAGCGTGCCCTTGAAGGTTTT
GTAAAATCAGTTGGTAAAGAGTTTAAACGTGGTATTACTGCACAGCTTATCTATGTGGAAGCAGGCGCAGAGCAGAATTT
AGACTCAACGCTACGTTTTTTCACGTCAGCGCGTTCAGCTTATGTGTCAGGACAGGTCGTACGTGTCAGTAATGGTTCCA
ATGTCGATGTCGATTGGAACCAACCACTAGGTGGCAAAACCATGCTAGTCACTGGCGCAAGTCGCGGTATTGGTGAAGCA
ATTGCCCGTGTATTGGCTCGTGAAGGGGCGCATGTTATTTGTTTAGATGTACCACAGCAGCAAGCTGACTTGCAGAAAGT
GGCAAGTGAAATTAGTGGTTCGGCTTTGACGGTGGATATTACCAGTGCTGATGCTGGTAAAGAAATCGCAGAAGCTGCAC
AAAAACGTGGTGGTTTGGATTCAGTGATTCATAATGCTGGTATCACACGCGATAAAACACTAGCAAACATGGATGATAAA
CAGTGGGATATGGTGCTCAATATCAATTTGGGCAGTATCGCTAAGCTCAACCGTTATTTACTAGATAACGATGTACTAAA
AGATGCTGCACGTATCGTCTGTGTGTCATCAATCTCAGGTATCGCTGGCAACTTGGGTCAAACCAACTATGCGACTTCAA
AAGCTGGTGTCATTGGTTTAGTCAATGCAACCGCCAAGCAGCTAGAAGACAATGCAAAAGGCATGACCATCAATGCAGTT
GCGCCAGGATTTATCGAAACGCAAATGACTGAAGCGATTCCATTTGCTATCCGTGAAGCAGGTCGTCGTATGAACTCGAT
GAGCCAAGGCGGTTTACCAGTCGATGTTGCAGAAACCATCGCATGGTTTGCATCGCCTGCTTCTGGTGGTCTAAATGGCA
ACGTTGTCCGCGTTTGTGGTCAAAGCTTATTGGGTGCATAA

Upstream 100 bases:

>100_bases
TAGTTTTTATAATCAATGCACTTTAGTAGCGCGCATTTCATCATAGATACATTTTATTCTTGTTTACTATTATCTTACTC
ATCAATTAAAGGATTATATT

Downstream 100 bases:

>100_bases
TTGTCCTAATACCATATGAAAATGCAGATAATAACGAGGGATATGTGAGCCATAAAGCTGGTCGCTGATTGCTTTTATTA
AGCAAGGTATTGAGGTTACT

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSDRYGDFVQSSIGKKVAKNLGLPMPVDLDRFDSGQPLVRGSVLVGRANGGDNAVSASVARILSELHTEIFVNSGDDVKD
TLSDAGVKAKANTGSDDKFKVLLFDASNISNAEELKQVYEFFHSVARRVEKSGRVIVIGRPPEALTDIEAALAQRALEGF
VKSVGKEFKRGITAQLIYVEAGAEQNLDSTLRFFTSARSAYVSGQVVRVSNGSNVDVDWNQPLGGKTMLVTGASRGIGEA
IARVLAREGAHVICLDVPQQQADLQKVASEISGSALTVDITSADAGKEIAEAAQKRGGLDSVIHNAGITRDKTLANMDDK
QWDMVLNINLGSIAKLNRYLLDNDVLKDAARIVCVSSISGIAGNLGQTNYATSKAGVIGLVNATAKQLEDNAKGMTINAV
APGFIETQMTEAIPFAIREAGRRMNSMSQGGLPVDVAETIAWFASPASGGLNGNVVRVCGQSLLGA

Sequences:

>Translated_466_residues
MSDRYGDFVQSSIGKKVAKNLGLPMPVDLDRFDSGQPLVRGSVLVGRANGGDNAVSASVARILSELHTEIFVNSGDDVKD
TLSDAGVKAKANTGSDDKFKVLLFDASNISNAEELKQVYEFFHSVARRVEKSGRVIVIGRPPEALTDIEAALAQRALEGF
VKSVGKEFKRGITAQLIYVEAGAEQNLDSTLRFFTSARSAYVSGQVVRVSNGSNVDVDWNQPLGGKTMLVTGASRGIGEA
IARVLAREGAHVICLDVPQQQADLQKVASEISGSALTVDITSADAGKEIAEAAQKRGGLDSVIHNAGITRDKTLANMDDK
QWDMVLNINLGSIAKLNRYLLDNDVLKDAARIVCVSSISGIAGNLGQTNYATSKAGVIGLVNATAKQLEDNAKGMTINAV
APGFIETQMTEAIPFAIREAGRRMNSMSQGGLPVDVAETIAWFASPASGGLNGNVVRVCGQSLLGA
>Mature_465_residues
SDRYGDFVQSSIGKKVAKNLGLPMPVDLDRFDSGQPLVRGSVLVGRANGGDNAVSASVARILSELHTEIFVNSGDDVKDT
LSDAGVKAKANTGSDDKFKVLLFDASNISNAEELKQVYEFFHSVARRVEKSGRVIVIGRPPEALTDIEAALAQRALEGFV
KSVGKEFKRGITAQLIYVEAGAEQNLDSTLRFFTSARSAYVSGQVVRVSNGSNVDVDWNQPLGGKTMLVTGASRGIGEAI
ARVLAREGAHVICLDVPQQQADLQKVASEISGSALTVDITSADAGKEIAEAAQKRGGLDSVIHNAGITRDKTLANMDDKQ
WDMVLNINLGSIAKLNRYLLDNDVLKDAARIVCVSSISGIAGNLGQTNYATSKAGVIGLVNATAKQLEDNAKGMTINAVA
PGFIETQMTEAIPFAIREAGRRMNSMSQGGLPVDVAETIAWFASPASGGLNGNVVRVCGQSLLGA

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=35.8870967741936, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4504505, Length=226, Percent_Identity=30.9734513274336, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=29.4354838709677, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=29.2307692307692, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI33667109, Length=209, Percent_Identity=31.5789473684211, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=30.327868852459, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI126723191, Length=174, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI66933014, Length=245, Percent_Identity=28.1632653061224, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI40807363, Length=195, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI126723750, Length=272, Percent_Identity=26.4705882352941, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI31542939, Length=198, Percent_Identity=28.2828282828283, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=35.655737704918, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=32.3886639676113, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=26.0162601626016, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790717, Length=250, Percent_Identity=26.4, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=26, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367365, Length=237, Percent_Identity=28.2700421940928, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=29.1828793774319, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=31.0483870967742, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787526, Length=197, Percent_Identity=29.9492385786802, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=25.390625, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=36.4754098360656, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=36.2903225806452, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=30.5220883534137, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=31.25, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=219, Percent_Identity=29.6803652968037, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538182, Length=208, Percent_Identity=27.8846153846154, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=25.9067357512953, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=193, Percent_Identity=25.9067357512953, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=242, Percent_Identity=28.9256198347107, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=215, Percent_Identity=27.906976744186, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=248, Percent_Identity=30.6451612903226, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=198, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=246, Percent_Identity=25.2032520325203, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562908, Length=246, Percent_Identity=29.6747967479675, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=211, Percent_Identity=30.8056872037915, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322226, Length=189, Percent_Identity=31.2169312169312, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=36.5853658536585, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI23397609, Length=232, Percent_Identity=34.9137931034483, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859837, Length=201, Percent_Identity=32.8358208955224, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644339, Length=237, Percent_Identity=35.0210970464135, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737361, Length=249, Percent_Identity=31.7269076305221, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24643142, Length=189, Percent_Identity=31.7460317460317, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357041, Length=231, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28571526, Length=235, Percent_Identity=31.9148936170213, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649181, Length=210, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 49194; Mature: 49063

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRYGDFVQSSIGKKVAKNLGLPMPVDLDRFDSGQPLVRGSVLVGRANGGDNAVSASVA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCHHHHHHHH
RILSELHTEIFVNSGDDVKDTLSDAGVKAKANTGSDDKFKVLLFDASNISNAEELKQVYE
HHHHHHHHHEEECCCCCHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
FFHSVARRVEKSGRVIVIGRPPEALTDIEAALAQRALEGFVKSVGKEFKRGITAQLIYVE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
AGAEQNLDSTLRFFTSARSAYVSGQVVRVSNGSNVDVDWNQPLGGKTMLVTGASRGIGEA
CCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEEECCCCCHHHH
IARVLAREGAHVICLDVPQQQADLQKVASEISGSALTVDITSADAGKEIAEAAQKRGGLD
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHH
SVIHNAGITRDKTLANMDDKQWDMVLNINLGSIAKLNRYLLDNDVLKDAARIVCVSSISG
HHHHHCCCCCCCHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHH
IAGNLGQTNYATSKAGVIGLVNATAKQLEDNAKGMTINAVAPGFIETQMTEAIPFAIREA
HHCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
GRRMNSMSQGGLPVDVAETIAWFASPASGGLNGNVVRVCGQSLLGA
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDRYGDFVQSSIGKKVAKNLGLPMPVDLDRFDSGQPLVRGSVLVGRANGGDNAVSASVA
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCHHHHHHHH
RILSELHTEIFVNSGDDVKDTLSDAGVKAKANTGSDDKFKVLLFDASNISNAEELKQVYE
HHHHHHHHHEEECCCCCHHHHHHHCCCEEECCCCCCCEEEEEEEECCCCCCHHHHHHHHH
FFHSVARRVEKSGRVIVIGRPPEALTDIEAALAQRALEGFVKSVGKEFKRGITAQLIYVE
HHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
AGAEQNLDSTLRFFTSARSAYVSGQVVRVSNGSNVDVDWNQPLGGKTMLVTGASRGIGEA
CCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCCEEEEECCCCCHHHH
IARVLAREGAHVICLDVPQQQADLQKVASEISGSALTVDITSADAGKEIAEAAQKRGGLD
HHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCHH
SVIHNAGITRDKTLANMDDKQWDMVLNINLGSIAKLNRYLLDNDVLKDAARIVCVSSISG
HHHHHCCCCCCCHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEHHHHHHH
IAGNLGQTNYATSKAGVIGLVNATAKQLEDNAKGMTINAVAPGFIETQMTEAIPFAIREA
HHCCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
GRRMNSMSQGGLPVDVAETIAWFASPASGGLNGNVVRVCGQSLLGA
HHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]