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The map label for this gene is cysS [H]

Identifier: 93005831

GI number: 93005831

Start: 1198174

End: 1199640

Strand: Direct

Name: cysS [H]

Synonym: Pcryo_1003

Alternate gene names: 93005831

Gene position: 1198174-1199640 (Clockwise)

Preceding gene: 93005829

Following gene: 93005832

Centisome position: 39.16

GC content: 45.88

Gene sequence:

>1467_bases
ATGACTATGACCACACCTCTTGCAGACGCGATGTCTCAGCTCGTCATCTATGACTCACTTACTGGACGCAAGCAAGCATT
CAAGCCGCTTGCCACGGGCAAAGTTGGCATGTATGTGTGTGGCATGACGGTTTATGATTATTGTCATATCGGTCACGCTC
GAGTGATGGTTGGCTTTGATATGGCAGTACGTTGGCTTGCACAATTGGGCTATGACGTAAATTACGTGCGTAATATTACT
GATATCGATGACAAAATCATCACCCGTGCTGCCGAAAATGGTGAAGAGATTGGCACATTGACCCAACGTTTTATTACTGC
CATGCATGAAGATGCGACAGCACTTGGCTGCTTGTCCCCTGATGCAGAACCGCGTGCGACCGATCATATCGATGAGATGC
AGCAGATGATTGAGACGTTGGTTAGTAATGACTATGCCTACGCGGGTGATAATGGTGATGTCTACTATGCAGTCGATAGC
TTCGCAGATTATGGCAAATTGTCAAAACGTAACCTTGATGATATGCAGGCAGGATCACGGGTTGAAGTCGAGAACGACAA
GCGCAATCCATTTGATTTTGTGTTATGGAAAGCGGCGAAACCGGATGAGCCGCAATGGGCATCAGCGTGGGGTCAAGGGC
GTCCAGGCTGGCATATTGAATGCTCAGCGATGTCGACCAAATGCCTTGGTAATACCTTTGATATCCATGGCGGCGGTCAT
GATTTACAGTTTCCGCATCATGAAAACGAGATTGCCCAATCTGAAGCAGCAACCGGCTGTGAATACGCGCGTAACTGGAT
GCACGTTGGTTTTATCAATGTTGATGGCGAAAAAATGTCTAAGTCATTGGGGAATTTCTTTACCATTCGTGATGTCATGG
CAAAATACTTACCAGAAACGGTTCGTTTCTTCTTATTGTCGAGTCATTATCGCAGTCAAGTAAACTTCTCTGATAGTGCC
TTGGACGAATCGCATAATAGCCTAAGCAGGTTGTATCAAGCATTAAAAGTTGCTGAACAACAAAAAGGTAAAGTACTTAT
TATCGATGAAGCCTTGATTAATAATGCCTACGCCAGTGCAGTGGGACAAGACTTTATCAAAGCCATGAATGACGACTTTA
ATAGCTCAACGGCAATCAGTGTGCTGTTTGGATTGGCGCGTGATATCAATAAAGCGAGTAAAGCACAAGATGTAGAGACT
GCATGGCAATTAGCGCAGCACTTAAAAGCTTTGGCGCAAACGCTTAATATTTTACAGCAGCCTGTGCAGCAGTTCTTGCA
AGCCGTCATTGGTGAAGTAGCTGAAGATAGTTTAACCGACGAAGCCATTGATGGGCTAATCATCGAGCGCGCTGATGCCA
AAACCAATAAAAACTTTGCGCGTGCTGATGAGATTCGTGTGCAGTTGAAAGAGGCTGGTATTGAGCTTGAAGACAGTCGT
GCGGGCACCACTTGGCGCCGTGCTTAA

Upstream 100 bases:

>100_bases
TTGATTTATGCATGATTTGCTTATGTAAGCGCTTTTTTATTGGCTAAGCGTACATGATTGCTAGGCTTGTTTTCTCTTAT
ACTTTTAATTTAAAGGCTTT

Downstream 100 bases:

>100_bases
TGTAAGCATTAGTTTTTTACGCTTGTTCATTCACAAACAATAATAAATTAAGCCAGCTATCTGCTGGCTTTTTTGTGTCT
TCTGCATTAGCTTAATATCA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MTMTTPLADAMSQLVIYDSLTGRKQAFKPLATGKVGMYVCGMTVYDYCHIGHARVMVGFDMAVRWLAQLGYDVNYVRNIT
DIDDKIITRAAENGEEIGTLTQRFITAMHEDATALGCLSPDAEPRATDHIDEMQQMIETLVSNDYAYAGDNGDVYYAVDS
FADYGKLSKRNLDDMQAGSRVEVENDKRNPFDFVLWKAAKPDEPQWASAWGQGRPGWHIECSAMSTKCLGNTFDIHGGGH
DLQFPHHENEIAQSEAATGCEYARNWMHVGFINVDGEKMSKSLGNFFTIRDVMAKYLPETVRFFLLSSHYRSQVNFSDSA
LDESHNSLSRLYQALKVAEQQKGKVLIIDEALINNAYASAVGQDFIKAMNDDFNSSTAISVLFGLARDINKASKAQDVET
AWQLAQHLKALAQTLNILQQPVQQFLQAVIGEVAEDSLTDEAIDGLIIERADAKTNKNFARADEIRVQLKEAGIELEDSR
AGTTWRRA

Sequences:

>Translated_488_residues
MTMTTPLADAMSQLVIYDSLTGRKQAFKPLATGKVGMYVCGMTVYDYCHIGHARVMVGFDMAVRWLAQLGYDVNYVRNIT
DIDDKIITRAAENGEEIGTLTQRFITAMHEDATALGCLSPDAEPRATDHIDEMQQMIETLVSNDYAYAGDNGDVYYAVDS
FADYGKLSKRNLDDMQAGSRVEVENDKRNPFDFVLWKAAKPDEPQWASAWGQGRPGWHIECSAMSTKCLGNTFDIHGGGH
DLQFPHHENEIAQSEAATGCEYARNWMHVGFINVDGEKMSKSLGNFFTIRDVMAKYLPETVRFFLLSSHYRSQVNFSDSA
LDESHNSLSRLYQALKVAEQQKGKVLIIDEALINNAYASAVGQDFIKAMNDDFNSSTAISVLFGLARDINKASKAQDVET
AWQLAQHLKALAQTLNILQQPVQQFLQAVIGEVAEDSLTDEAIDGLIIERADAKTNKNFARADEIRVQLKEAGIELEDSR
AGTTWRRA
>Mature_487_residues
TMTTPLADAMSQLVIYDSLTGRKQAFKPLATGKVGMYVCGMTVYDYCHIGHARVMVGFDMAVRWLAQLGYDVNYVRNITD
IDDKIITRAAENGEEIGTLTQRFITAMHEDATALGCLSPDAEPRATDHIDEMQQMIETLVSNDYAYAGDNGDVYYAVDSF
ADYGKLSKRNLDDMQAGSRVEVENDKRNPFDFVLWKAAKPDEPQWASAWGQGRPGWHIECSAMSTKCLGNTFDIHGGGHD
LQFPHHENEIAQSEAATGCEYARNWMHVGFINVDGEKMSKSLGNFFTIRDVMAKYLPETVRFFLLSSHYRSQVNFSDSAL
DESHNSLSRLYQALKVAEQQKGKVLIIDEALINNAYASAVGQDFIKAMNDDFNSSTAISVLFGLARDINKASKAQDVETA
WQLAQHLKALAQTLNILQQPVQQFLQAVIGEVAEDSLTDEAIDGLIIERADAKTNKNFARADEIRVQLKEAGIELEDSRA
GTTWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=388, Percent_Identity=39.6907216494845, Blast_Score=258, Evalue=1e-68,
Organism=Homo sapiens, GI10835051, Length=232, Percent_Identity=40.948275862069, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI62240992, Length=232, Percent_Identity=40.948275862069, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI303304987, Length=232, Percent_Identity=40.948275862069, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI21269877, Length=232, Percent_Identity=40.948275862069, Blast_Score=191, Evalue=2e-48,
Organism=Escherichia coli, GI1786737, Length=474, Percent_Identity=53.3755274261603, Blast_Score=495, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17509795, Length=233, Percent_Identity=38.1974248927039, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17509797, Length=233, Percent_Identity=38.1974248927039, Blast_Score=175, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6324082, Length=277, Percent_Identity=34.6570397111913, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI19922218, Length=480, Percent_Identity=34.375, Blast_Score=242, Evalue=3e-64,
Organism=Drosophila melanogaster, GI19922364, Length=229, Percent_Identity=38.8646288209607, Blast_Score=176, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 54361; Mature: 54229

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTTPLADAMSQLVIYDSLTGRKQAFKPLATGKVGMYVCGMTVYDYCHIGHARVMVGFD
CCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEHHH
MAVRWLAQLGYDVNYVRNITDIDDKIITRAAENGEEIGTLTQRFITAMHEDATALGCLSP
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
DAEPRATDHIDEMQQMIETLVSNDYAYAGDNGDVYYAVDSFADYGKLSKRNLDDMQAGSR
CCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCHHHHHHHHCCCHHHCCCCE
VEVENDKRNPFDFVLWKAAKPDEPQWASAWGQGRPGWHIECSAMSTKCLGNTFDIHGGGH
EEECCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCCEEEECCCCHHHCCCCEEECCCCC
DLQFPHHENEIAQSEAATGCEYARNWMHVGFINVDGEKMSKSLGNFFTIRDVMAKYLPET
CCCCCCCHHHHHHHHHHCCHHHHHCCEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHH
VRFFLLSSHYRSQVNFSDSALDESHNSLSRLYQALKVAEQQKGKVLIIDEALINNAYASA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
VGQDFIKAMNDDFNSSTAISVLFGLARDINKASKAQDVETAWQLAQHLKALAQTLNILQQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVQQFLQAVIGEVAEDSLTDEAIDGLIIERADAKTNKNFARADEIRVQLKEAGIELEDSR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEECCC
AGTTWRRA
CCCCCCCC
>Mature Secondary Structure 
TMTTPLADAMSQLVIYDSLTGRKQAFKPLATGKVGMYVCGMTVYDYCHIGHARVMVGFD
CCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHEEEHHH
MAVRWLAQLGYDVNYVRNITDIDDKIITRAAENGEEIGTLTQRFITAMHEDATALGCLSP
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEECCCC
DAEPRATDHIDEMQQMIETLVSNDYAYAGDNGDVYYAVDSFADYGKLSKRNLDDMQAGSR
CCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCHHHHHHHHCCCHHHCCCCE
VEVENDKRNPFDFVLWKAAKPDEPQWASAWGQGRPGWHIECSAMSTKCLGNTFDIHGGGH
EEECCCCCCCCEEEEEECCCCCCCCHHHHCCCCCCCCEEEECCCCHHHCCCCEEECCCCC
DLQFPHHENEIAQSEAATGCEYARNWMHVGFINVDGEKMSKSLGNFFTIRDVMAKYLPET
CCCCCCCHHHHHHHHHHCCHHHHHCCEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHHH
VRFFLLSSHYRSQVNFSDSALDESHNSLSRLYQALKVAEQQKGKVLIIDEALINNAYASA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
VGQDFIKAMNDDFNSSTAISVLFGLARDINKASKAQDVETAWQLAQHLKALAQTLNILQQ
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PVQQFLQAVIGEVAEDSLTDEAIDGLIIERADAKTNKNFARADEIRVQLKEAGIELEDSR
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCEEECCC
AGTTWRRA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA