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The map label for this gene is livH [H]

Identifier: 93005821

GI number: 93005821

Start: 1182816

End: 1184594

Strand: Reverse

Name: livH [H]

Synonym: Pcryo_0993

Alternate gene names: 93005821

Gene position: 1184594-1182816 (Counterclockwise)

Preceding gene: 93005822

Following gene: 93005820

Centisome position: 38.71

GC content: 46.49

Gene sequence:

>1779_bases
ATGTCACATTACCCTTCCTATTATAAAAGTGACGCGCAAGCCAATTATTCTAATAAGATTTTTATCATCGCCTTACTATC
TTTACTCCTTCTCATTGCTATCACATCACCTGCTCATGCTCACGAGACGCCAGTAGTACACAGCCATGGCGACAAACTAT
CGACTAATACTGTGGCAGCGACATCCACTGATGTAAGTGAAGAGACCTTATTTGCTCAAAAAAAGCAGTCTCTAACTACG
CCAGCTAATCTTGCGATAAGTAAAGGGGATGCTATCGAGCAGTTCGTTGCTGCTGACTTCACCAAGCGCCAAACCATGCT
CAACCAGTGGCCGGGATCAGTTGAGAGTTTGGATACTTTAGTTGAGCTGATAAAAAACGATGAGCTATACCAAGGCAATG
GTGGGCAAACTTATCTACTTAACAGCGAAGATGAGCTATTTACTTATCCTGCTAAGCAGCTGACCACCGAGTGGCCTAGC
GACTTGGCGCAAGTGACTTTGACCAATACGCTACGCTCAGCCTTAGTATTTGGACAAGCCAAGGTTAAGCTTGAGTCAAA
TGATCCTACGCAACGTGTGCAGGCAGTCGCCATCTTAGCGGACAATATCGAACAGCTAGATCCAGCACTCATAAGTACTG
CTGCCACTAATGAGGAAGACGACGACGTCAAAACAGCGTTGAGTACTTTACAAGCGAGGATTGATTTTAGAGACGGCGAC
GTTACTACCCAAATTGCCGCGCTTACCGTGCTTGCTGATAGCGATAGCCCGCAAGTCTTAGTTGATGTCAAAAAAGCATT
GGCGGCAGATGATATCGATCCTGTACTCAAATCCGCGCTGTTAGACGCTGAAGAAAGTATTGAGCAGCGCATTACCCTCA
GTACTTGGATAGGTCATCTGTTCACGGGGCTTAGTACGGCAAGTATCTTACTACTGGCGGCATTAGGGCTGGCCATTACT
TTTGGGCTACTGGGTGTCATCAATATGGCTCATGGTGAGCTCATTATGATTGGTGCTTACGCCACTTATATGGTGCAAAA
TCTCTTTCAAGCGTATTTTCCTAGTATGACTGGATGGTATCTGGTTGCTGCTATACCCGTCGCTTTCTTAGTTAGTGCCA
TTATTGGCATGGTTATCGAACGAATCATTATTCGCCCGCTTTATGGTCGTGAGCTTGAAACCTTACTGGCAACCTTCGGT
GTCAGTCTGATTCTCATGCAGTTGGTTCGGATGATATTTGGCGCGCAAAACGTCGAAGTCAGCAATGTCGACTGGTTGAG
CGGTGCCTATCAAGTCTCCTCGATCCTTGTGCTTCCCTTCAATCGTATCGCTATTATTGGCTTTACCATCATTATTCTTA
TGCTACTGGTGTACTTACTGAACAAGACTCGCTTTGGGTTGTTTGTGCGCGCTGTCACTCAAAACCGGCAAATGGCACGT
GCAGTTGGTATCTCATCTGCTCGCATCGATATGTTGGCTTTTGGACTTGGCTCGGGTCTCGCAGGTCTCGCTGGCTGTGC
TTTGGCGCAAGTAGGCAATGTCGGACCCGACTTAGGTCAAACTTATATTATTGATGCGTTCTTAGTCGTCGTGGTTGGCG
GTGTTGGGCAAGTATGGGGCGCGGTCTTGGCATCTTTAGGTCTTGGTGTCAGTGGTACGGTGCTTGAAATCGGCATTGGT
GCTGTGATGGCTAAGATTGTATTACTGGTTCTTGTGATTTTGTTTATTCAAAAACGTCCACAAGGTTTATTCGCCCTCAA
AGGCCGTTTTGTGGATTAA

Upstream 100 bases:

>100_bases
CCCTTAATGGTATCAATACCAGCAACCCTTTAGCTCCTCTACTGATAAAACAGTTTTCAGTAGAGGTTAGAGGAGTGTTG
ACTGCAAAAAAGGAACCATC

Downstream 100 bases:

>100_bases
GGAGAACCTCATGCGTTTGACTCAATTATTATCTGATTCCCCACGTAATGCCATTTTGATTGGTTTGTGTTTTTTAGTGC
TACTGATATTGCCTTGGCTC

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSHYPSYYKSDAQANYSNKIFIIALLSLLLLIAITSPAHAHETPVVHSHGDKLSTNTVAATSTDVSEETLFAQKKQSLTT
PANLAISKGDAIEQFVAADFTKRQTMLNQWPGSVESLDTLVELIKNDELYQGNGGQTYLLNSEDELFTYPAKQLTTEWPS
DLAQVTLTNTLRSALVFGQAKVKLESNDPTQRVQAVAILADNIEQLDPALISTAATNEEDDDVKTALSTLQARIDFRDGD
VTTQIAALTVLADSDSPQVLVDVKKALAADDIDPVLKSALLDAEESIEQRITLSTWIGHLFTGLSTASILLLAALGLAIT
FGLLGVINMAHGELIMIGAYATYMVQNLFQAYFPSMTGWYLVAAIPVAFLVSAIIGMVIERIIIRPLYGRELETLLATFG
VSLILMQLVRMIFGAQNVEVSNVDWLSGAYQVSSILVLPFNRIAIIGFTIIILMLLVYLLNKTRFGLFVRAVTQNRQMAR
AVGISSARIDMLAFGLGSGLAGLAGCALAQVGNVGPDLGQTYIIDAFLVVVVGGVGQVWGAVLASLGLGVSGTVLEIGIG
AVMAKIVLLVLVILFIQKRPQGLFALKGRFVD

Sequences:

>Translated_592_residues
MSHYPSYYKSDAQANYSNKIFIIALLSLLLLIAITSPAHAHETPVVHSHGDKLSTNTVAATSTDVSEETLFAQKKQSLTT
PANLAISKGDAIEQFVAADFTKRQTMLNQWPGSVESLDTLVELIKNDELYQGNGGQTYLLNSEDELFTYPAKQLTTEWPS
DLAQVTLTNTLRSALVFGQAKVKLESNDPTQRVQAVAILADNIEQLDPALISTAATNEEDDDVKTALSTLQARIDFRDGD
VTTQIAALTVLADSDSPQVLVDVKKALAADDIDPVLKSALLDAEESIEQRITLSTWIGHLFTGLSTASILLLAALGLAIT
FGLLGVINMAHGELIMIGAYATYMVQNLFQAYFPSMTGWYLVAAIPVAFLVSAIIGMVIERIIIRPLYGRELETLLATFG
VSLILMQLVRMIFGAQNVEVSNVDWLSGAYQVSSILVLPFNRIAIIGFTIIILMLLVYLLNKTRFGLFVRAVTQNRQMAR
AVGISSARIDMLAFGLGSGLAGLAGCALAQVGNVGPDLGQTYIIDAFLVVVVGGVGQVWGAVLASLGLGVSGTVLEIGIG
AVMAKIVLLVLVILFIQKRPQGLFALKGRFVD
>Mature_591_residues
SHYPSYYKSDAQANYSNKIFIIALLSLLLLIAITSPAHAHETPVVHSHGDKLSTNTVAATSTDVSEETLFAQKKQSLTTP
ANLAISKGDAIEQFVAADFTKRQTMLNQWPGSVESLDTLVELIKNDELYQGNGGQTYLLNSEDELFTYPAKQLTTEWPSD
LAQVTLTNTLRSALVFGQAKVKLESNDPTQRVQAVAILADNIEQLDPALISTAATNEEDDDVKTALSTLQARIDFRDGDV
TTQIAALTVLADSDSPQVLVDVKKALAADDIDPVLKSALLDAEESIEQRITLSTWIGHLFTGLSTASILLLAALGLAITF
GLLGVINMAHGELIMIGAYATYMVQNLFQAYFPSMTGWYLVAAIPVAFLVSAIIGMVIERIIIRPLYGRELETLLATFGV
SLILMQLVRMIFGAQNVEVSNVDWLSGAYQVSSILVLPFNRIAIIGFTIIILMLLVYLLNKTRFGLFVRAVTQNRQMARA
VGISSARIDMLAFGLGSGLAGLAGCALAQVGNVGPDLGQTYIIDAFLVVVVGGVGQVWGAVLASLGLGVSGTVLEIGIGA
VMAKIVLLVLVILFIQKRPQGLFALKGRFVD

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=291, Percent_Identity=29.553264604811, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 63664; Mature: 63533

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYPSYYKSDAQANYSNKIFIIALLSLLLLIAITSPAHAHETPVVHSHGDKLSTNTVAA
CCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEE
TSTDVSEETLFAQKKQSLTTPANLAISKGDAIEQFVAADFTKRQTMLNQWPGSVESLDTL
CCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VELIKNDELYQGNGGQTYLLNSEDELFTYPAKQLTTEWPSDLAQVTLTNTLRSALVFGQA
HHHHCCCCEEECCCCCEEEECCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCE
KVKLESNDPTQRVQAVAILADNIEQLDPALISTAATNEEDDDVKTALSTLQARIDFRDGD
EEEECCCCHHHHHHHHHHHHHCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
VTTQIAALTVLADSDSPQVLVDVKKALAADDIDPVLKSALLDAEESIEQRITLSTWIGHL
HHHHEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FTGLSTASILLLAALGLAITFGLLGVINMAHGELIMIGAYATYMVQNLFQAYFPSMTGWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHH
LVAAIPVAFLVSAIIGMVIERIIIRPLYGRELETLLATFGVSLILMQLVRMIFGAQNVEV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SNVDWLSGAYQVSSILVLPFNRIAIIGFTIIILMLLVYLLNKTRFGLFVRAVTQNRQMAR
CCCHHHCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
AVGISSARIDMLAFGLGSGLAGLAGCALAQVGNVGPDLGQTYIIDAFLVVVVGGVGQVWG
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
AVLASLGLGVSGTVLEIGIGAVMAKIVLLVLVILFIQKRPQGLFALKGRFVD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC
>Mature Secondary Structure 
SHYPSYYKSDAQANYSNKIFIIALLSLLLLIAITSPAHAHETPVVHSHGDKLSTNTVAA
CCCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEE
TSTDVSEETLFAQKKQSLTTPANLAISKGDAIEQFVAADFTKRQTMLNQWPGSVESLDTL
CCCCCHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
VELIKNDELYQGNGGQTYLLNSEDELFTYPAKQLTTEWPSDLAQVTLTNTLRSALVFGQA
HHHHCCCCEEECCCCCEEEECCCCCEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHCCE
KVKLESNDPTQRVQAVAILADNIEQLDPALISTAATNEEDDDVKTALSTLQARIDFRDGD
EEEECCCCHHHHHHHHHHHHHCHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
VTTQIAALTVLADSDSPQVLVDVKKALAADDIDPVLKSALLDAEESIEQRITLSTWIGHL
HHHHEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
FTGLSTASILLLAALGLAITFGLLGVINMAHGELIMIGAYATYMVQNLFQAYFPSMTGWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCCCHHH
LVAAIPVAFLVSAIIGMVIERIIIRPLYGRELETLLATFGVSLILMQLVRMIFGAQNVEV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SNVDWLSGAYQVSSILVLPFNRIAIIGFTIIILMLLVYLLNKTRFGLFVRAVTQNRQMAR
CCCHHHCCHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHH
AVGISSARIDMLAFGLGSGLAGLAGCALAQVGNVGPDLGQTYIIDAFLVVVVGGVGQVWG
HHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
AVLASLGLGVSGTVLEIGIGAVMAKIVLLVLVILFIQKRPQGLFALKGRFVD
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]