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The map label for this gene is cvrA [H]

Identifier: 93005794

GI number: 93005794

Start: 1152543

End: 1154333

Strand: Direct

Name: cvrA [H]

Synonym: Pcryo_0966

Alternate gene names: 93005794

Gene position: 1152543-1154333 (Clockwise)

Preceding gene: 93005793

Following gene: 93005797

Centisome position: 37.67

GC content: 44.39

Gene sequence:

>1791_bases
ATGGATACCTTAAATATCCTATACCTTGTAGGGGCATTGTTAATTTTCGCCAGTATCATGGCAAGCACGTTATCAGCACG
TTTGGGCGTTCCTTTATTACTGCTGTTTTTAATGGTAGGAATGCTGGCTGGTGAAGAGGGTATCTTAGGTATCGAGTTTT
CCCAATATGCTATTGCTAATTTTGTTGGTCAGGCAGCTTTAGCCTGTATCTTGTTAGATGGTGGTCTACGTACCTCTTTT
AATTCCTTTCGCGTTGGTCTTAAGCCTGCCGTTACCCTCGCAACTTGGGGTGTCCTCGCGACTGTCATGATACTGGGCAT
ATTTGTGACTTGGCTACTTGATGTCGATTGGCGTTTTGGCTTGTTAATGGCAGCGATTGTCGGTTCGACCGATGCGGCAG
CGGTCTTTTCATTGCTGCGTAATGGCGGTGTCAAGCTTAACGACCGTGTACAAGCCACATTGGAGCTGGAATCTGGTGCC
AATGATCCTTTGGCTATTTTGCTTGTAACCGGATTGATTGCCTTAAATGTCGATCCCGAAGGGCAAACGTTACTGGGCTT
TTTAGGGTTGCTATTACAGCAGCTTAGCTTTGGTCTTGGCATGGGTCTGCTGTTCGGCTATTTATTAGCCAGGCTATTAC
CCAAGATACTGTTAGCGGAAGGTATGTACGCTATCTTAATTATGTCTGCTGGCTTGGCAGTCTTTGCCGCGACCAACCTT
ATTGGCGGCAGTGGATTTTTGGCGATTTACCTCACTGGTGTGCTGATTGGGAACCATAAAGTCCGCTCAACCGAGCATGT
CATGCGGGTCATGGACAGCTTTGCTTGGTTGTCTCAAGCGGTGCTGTTTGTGGTGCTAGGTTTGCTCGTGACGCCATCGA
ACGTTATCGATGTTTGGTATTATTCAGTGGCGATTGCCGCCTTTATGATTTTAGTTGCTCGTCCTATTGCAGTTTATACT
AGCGTTAAACCTTTTAAATTCAAAGACAGAGAAATTGGCTTTATCTCTTGGGTAGGACTGCGCGGGGCAGTACCTATTAC
CCTTGCGATATTGCCAGTTATGGCAGGCATAGATGGTGCCTTTATGCTATTCGATATTGCCTTTGGTGTAGTGGTGTTGT
CTTTGATTTTGCAAGGCACGACCATTCCTATTATGGCAAATTTGTTTAAAGTACGTATTCCGAATAATAAAGACCCAGAA
GAAGAACATGAAGTTTGGGTATCTGATAAAGCGAGCATTACCTTATATGAATTTGAAGTAAAGTCTGGTGCATTTGCGAT
TGACCGTCATCCGATGGGCATCTCTAACCGTGTCAGCCCTGATGAGATTAGTATCTTTGCTTTGGTACGTCGGCAACACA
TTGTGATGGTTGAAGAAACGACCAAGCTCAAATGTGGGGATAGAGTCTGGTATGCGATGAGAGGTAATCATGCCAGTCAA
ATTGCCAAGATTTTCAATGATACGACACTCGATCGTAAAGCCATTGATGACTTTTATGGCGACTGGTTGCTATCACCCAG
TGTGAAGCTTGGAGATTTGCCTTTTTTTACCGATATCATGGCGTCTGAGTCTCTTGTAGATAAGCTAAAGGCAAAACCTG
AAAATACTTCAAAAATTATGTGGGAGCAGACGGTCGCTGAGTATGTCATAGACAATTTGGATATGAAGCCAGTATCAGGC
GATACGGTTGCTATCAGTGATGAGTGGTCATTGGTCATCAAAGAAGTGGACGATAAAGGAAAGCTAAGAACGATTGGTTT
AAAGCACTTGGAGTTTGCTAAAGCGATTTGA

Upstream 100 bases:

>100_bases
ATGTTATGCTTAGGAGCGGCTTTTACCGTAACGAAATCAGAGCAACATTATTACGATAATTGTATTTGTCGTCATTCATA
AAAATAGGGCTTAAAAAAAG

Downstream 100 bases:

>100_bases
TTTTTTGCTATAGTGACTTCAGTATTAAAACGATACAGTGGGACTGGGATGACTATTGAAAAGCGCTATTGATAATCAAT
AGCGCTTTTCAATAGTATTA

Product: potassium/proton antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MDTLNILYLVGALLIFASIMASTLSARLGVPLLLLFLMVGMLAGEEGILGIEFSQYAIANFVGQAALACILLDGGLRTSF
NSFRVGLKPAVTLATWGVLATVMILGIFVTWLLDVDWRFGLLMAAIVGSTDAAAVFSLLRNGGVKLNDRVQATLELESGA
NDPLAILLVTGLIALNVDPEGQTLLGFLGLLLQQLSFGLGMGLLFGYLLARLLPKILLAEGMYAILIMSAGLAVFAATNL
IGGSGFLAIYLTGVLIGNHKVRSTEHVMRVMDSFAWLSQAVLFVVLGLLVTPSNVIDVWYYSVAIAAFMILVARPIAVYT
SVKPFKFKDREIGFISWVGLRGAVPITLAILPVMAGIDGAFMLFDIAFGVVVLSLILQGTTIPIMANLFKVRIPNNKDPE
EEHEVWVSDKASITLYEFEVKSGAFAIDRHPMGISNRVSPDEISIFALVRRQHIVMVEETTKLKCGDRVWYAMRGNHASQ
IAKIFNDTTLDRKAIDDFYGDWLLSPSVKLGDLPFFTDIMASESLVDKLKAKPENTSKIMWEQTVAEYVIDNLDMKPVSG
DTVAISDEWSLVIKEVDDKGKLRTIGLKHLEFAKAI

Sequences:

>Translated_596_residues
MDTLNILYLVGALLIFASIMASTLSARLGVPLLLLFLMVGMLAGEEGILGIEFSQYAIANFVGQAALACILLDGGLRTSF
NSFRVGLKPAVTLATWGVLATVMILGIFVTWLLDVDWRFGLLMAAIVGSTDAAAVFSLLRNGGVKLNDRVQATLELESGA
NDPLAILLVTGLIALNVDPEGQTLLGFLGLLLQQLSFGLGMGLLFGYLLARLLPKILLAEGMYAILIMSAGLAVFAATNL
IGGSGFLAIYLTGVLIGNHKVRSTEHVMRVMDSFAWLSQAVLFVVLGLLVTPSNVIDVWYYSVAIAAFMILVARPIAVYT
SVKPFKFKDREIGFISWVGLRGAVPITLAILPVMAGIDGAFMLFDIAFGVVVLSLILQGTTIPIMANLFKVRIPNNKDPE
EEHEVWVSDKASITLYEFEVKSGAFAIDRHPMGISNRVSPDEISIFALVRRQHIVMVEETTKLKCGDRVWYAMRGNHASQ
IAKIFNDTTLDRKAIDDFYGDWLLSPSVKLGDLPFFTDIMASESLVDKLKAKPENTSKIMWEQTVAEYVIDNLDMKPVSG
DTVAISDEWSLVIKEVDDKGKLRTIGLKHLEFAKAI
>Mature_596_residues
MDTLNILYLVGALLIFASIMASTLSARLGVPLLLLFLMVGMLAGEEGILGIEFSQYAIANFVGQAALACILLDGGLRTSF
NSFRVGLKPAVTLATWGVLATVMILGIFVTWLLDVDWRFGLLMAAIVGSTDAAAVFSLLRNGGVKLNDRVQATLELESGA
NDPLAILLVTGLIALNVDPEGQTLLGFLGLLLQQLSFGLGMGLLFGYLLARLLPKILLAEGMYAILIMSAGLAVFAATNL
IGGSGFLAIYLTGVLIGNHKVRSTEHVMRVMDSFAWLSQAVLFVVLGLLVTPSNVIDVWYYSVAIAAFMILVARPIAVYT
SVKPFKFKDREIGFISWVGLRGAVPITLAILPVMAGIDGAFMLFDIAFGVVVLSLILQGTTIPIMANLFKVRIPNNKDPE
EEHEVWVSDKASITLYEFEVKSGAFAIDRHPMGISNRVSPDEISIFALVRRQHIVMVEETTKLKCGDRVWYAMRGNHASQ
IAKIFNDTTLDRKAIDDFYGDWLLSPSVKLGDLPFFTDIMASESLVDKLKAKPENTSKIMWEQTVAEYVIDNLDMKPVSG
DTVAISDEWSLVIKEVDDKGKLRTIGLKHLEFAKAI

Specific function: Participates in control of cell volume in low-osmolarity conditions [H]

COG id: COG3263

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87081854, Length=599, Percent_Identity=39.5659432387312, Blast_Score=338, Evalue=8e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR016169
- InterPro:   IPR006037
- InterPro:   IPR005170 [H]

Pfam domain/function: PF03471 CorC_HlyC; PF00999 Na_H_Exchanger; PF02080 TrkA_C [H]

EC number: NA

Molecular weight: Translated: 64945; Mature: 64945

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLNILYLVGALLIFASIMASTLSARLGVPLLLLFLMVGMLAGEEGILGIEFSQYAIAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
FVGQAALACILLDGGLRTSFNSFRVGLKPAVTLATWGVLATVMILGIFVTWLLDVDWRFG
HHHHHHHHHHEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLMAAIVGSTDAAAVFSLLRNGGVKLNDRVQATLELESGANDPLAILLVTGLIALNVDPE
HHHHHHHCCCHHHHHHHHHHCCCCEECCCEEEEEEECCCCCCCHHHHHHHHHHEEECCCC
GQTLLGFLGLLLQQLSFGLGMGLLFGYLLARLLPKILLAEGMYAILIMSAGLAVFAATNL
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
IGGSGFLAIYLTGVLIGNHKVRSTEHVMRVMDSFAWLSQAVLFVVLGLLVTPSNVIDVWY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YSVAIAAFMILVARPIAVYTSVKPFKFKDREIGFISWVGLRGAVPITLAILPVMAGIDGA
HHHHHHHHHHHHHCCHHHHCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHH
FMLFDIAFGVVVLSLILQGTTIPIMANLFKVRIPNNKDPEEEHEVWVSDKASITLYEFEV
HHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEECCCCCCCCHHHCEEECCCCEEEEEEEEE
KSGAFAIDRHPMGISNRVSPDEISIFALVRRQHIVMVEETTKLKCGDRVWYAMRGNHASQ
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCCHHH
IAKIFNDTTLDRKAIDDFYGDWLLSPSVKLGDLPFFTDIMASESLVDKLKAKPENTSKIM
HHHHHCCCCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
WEQTVAEYVIDNLDMKPVSGDTVAISDEWSLVIKEVDDKGKLRTIGLKHLEFAKAI
HHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEECHHHHHHHHCC
>Mature Secondary Structure
MDTLNILYLVGALLIFASIMASTLSARLGVPLLLLFLMVGMLAGEEGILGIEFSQYAIAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
FVGQAALACILLDGGLRTSFNSFRVGLKPAVTLATWGVLATVMILGIFVTWLLDVDWRFG
HHHHHHHHHHEECCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LLMAAIVGSTDAAAVFSLLRNGGVKLNDRVQATLELESGANDPLAILLVTGLIALNVDPE
HHHHHHHCCCHHHHHHHHHHCCCCEECCCEEEEEEECCCCCCCHHHHHHHHHHEEECCCC
GQTLLGFLGLLLQQLSFGLGMGLLFGYLLARLLPKILLAEGMYAILIMSAGLAVFAATNL
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
IGGSGFLAIYLTGVLIGNHKVRSTEHVMRVMDSFAWLSQAVLFVVLGLLVTPSNVIDVWY
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YSVAIAAFMILVARPIAVYTSVKPFKFKDREIGFISWVGLRGAVPITLAILPVMAGIDGA
HHHHHHHHHHHHHCCHHHHCCCCCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHH
FMLFDIAFGVVVLSLILQGTTIPIMANLFKVRIPNNKDPEEEHEVWVSDKASITLYEFEV
HHHHHHHHHHHHHHHHHCCCCHHHHHCEEEEECCCCCCCCHHHCEEECCCCEEEEEEEEE
KSGAFAIDRHPMGISNRVSPDEISIFALVRRQHIVMVEETTKLKCGDRVWYAMRGNHASQ
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCEEEEEECCCCCCCCCEEEEEECCCCHHH
IAKIFNDTTLDRKAIDDFYGDWLLSPSVKLGDLPFFTDIMASESLVDKLKAKPENTSKIM
HHHHHCCCCCHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHH
WEQTVAEYVIDNLDMKPVSGDTVAISDEWSLVIKEVDDKGKLRTIGLKHLEFAKAI
HHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEECCCCCCEEEECHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA