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The map label for this gene is siaP [H]

Identifier: 93005739

GI number: 93005739

Start: 1077587

End: 1078639

Strand: Direct

Name: siaP [H]

Synonym: Pcryo_0911

Alternate gene names: 93005739

Gene position: 1077587-1078639 (Clockwise)

Preceding gene: 93005737

Following gene: 93005744

Centisome position: 35.22

GC content: 40.65

Gene sequence:

>1053_bases
ATGAAATTAGCACCTTTTTTTTCGATAGGTGCACTAGCAGCTATTAGCCTTTTTGGTTGTTCTGGCCAATCTGATAACAG
TAGCGAAGTTGCCTCAAATCAAGAAGTTACCGTTCTACGTTTCTCCCATTTTTATCCCGCCACTGCTGATGTTAATAAAG
AAATCTTTGAGCCATGGGCCAAAAAAATTGGAGAAGATTCTAATGGTCGTCTTAAGGTTGAGGTATATCCATCGGCAACA
CTCAGTAAAGCAGATACCGCTTATGAATCCACAGTAAAGGGAACGATTGACATCGGTTCTCAAGTACAGGGTTATACTAG
TGGTCGCTTTCCACTGACCCAGATTGCAGAGCTTCCCGGTTTGTCTAATTCATCAACACAGACAGGTTGTATGCTGCAAA
CCCTTTATGAAAATGGCACTATATCTAGCGAATATGAAGATTCACATCTCCTTTTTATGTTCGCTACCGGCCCTGGTACA
TTACATAGTGCTGATAAGCTTATTCGAACTCCCGAAGATATGAAAGGGATGCGTATCCGCAGGCCATCTGCTGTAGCAGG
TGATATTATCGAAAGTATGGGTGCCTCTCCTGTGGGTTTACCTGCCAATGATATATATACGTCTCTACAGCGCGGTGTGG
TTGATGGATTGAGCTTTCCATGGGAGGCGATCACAACTTTCAAGCTTGATGAGTTAACCAAATATCATACCAATATCCCA
TTTTATAGTTCTGCTCTGATGATGACTATGAATAAAGATAAATATGAAAGTTTGCCTGATGATTTAAAAAAGGTCATTGA
TGATAACTCAGGTATGGCTCTTACTAAGAAAGTTGGTGAGATGTGGGATAGAACTGATTTATTAGGTTTGCAAGCTGCTA
AAGATAGAGGTGATGAGATCATTGATATTTCAGATCCACTTAATGATCCAGATTGGAAAGGACCTCTGCTAAAAGGAACA
CAAAAATACTTAGACGATGTAAGCGCATTAGGACTCGATGCTGAAAGTGTCTATGAAAAAGCAAAAGCTGCTAGTGTGGC
CTGTAAGGTTTAA

Upstream 100 bases:

>100_bases
CAGTTTTAATTTAAAGTGCTTATGTCTTTTAAGGCAGATTAATTAAGTCTTAATACCAATCAAATGTCAAAAAAATAATC
GCTATCAAAAGGAATTGATA

Downstream 100 bases:

>100_bases
TTATATTTTTAATATTAGGACGTGTCATCAAGTCTTGTACAACCCCTGAAAATTCGACAAAAAAAAGCCTCACTGTTAAG
TGAGGCTTTTTAAGTATTTG

Product: TRAP dicarboxylate transporter subunit DctP

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKLAPFFSIGALAAISLFGCSGQSDNSSEVASNQEVTVLRFSHFYPATADVNKEIFEPWAKKIGEDSNGRLKVEVYPSAT
LSKADTAYESTVKGTIDIGSQVQGYTSGRFPLTQIAELPGLSNSSTQTGCMLQTLYENGTISSEYEDSHLLFMFATGPGT
LHSADKLIRTPEDMKGMRIRRPSAVAGDIIESMGASPVGLPANDIYTSLQRGVVDGLSFPWEAITTFKLDELTKYHTNIP
FYSSALMMTMNKDKYESLPDDLKKVIDDNSGMALTKKVGEMWDRTDLLGLQAAKDRGDEIIDISDPLNDPDWKGPLLKGT
QKYLDDVSALGLDAESVYEKAKAASVACKV

Sequences:

>Translated_350_residues
MKLAPFFSIGALAAISLFGCSGQSDNSSEVASNQEVTVLRFSHFYPATADVNKEIFEPWAKKIGEDSNGRLKVEVYPSAT
LSKADTAYESTVKGTIDIGSQVQGYTSGRFPLTQIAELPGLSNSSTQTGCMLQTLYENGTISSEYEDSHLLFMFATGPGT
LHSADKLIRTPEDMKGMRIRRPSAVAGDIIESMGASPVGLPANDIYTSLQRGVVDGLSFPWEAITTFKLDELTKYHTNIP
FYSSALMMTMNKDKYESLPDDLKKVIDDNSGMALTKKVGEMWDRTDLLGLQAAKDRGDEIIDISDPLNDPDWKGPLLKGT
QKYLDDVSALGLDAESVYEKAKAASVACKV
>Mature_350_residues
MKLAPFFSIGALAAISLFGCSGQSDNSSEVASNQEVTVLRFSHFYPATADVNKEIFEPWAKKIGEDSNGRLKVEVYPSAT
LSKADTAYESTVKGTIDIGSQVQGYTSGRFPLTQIAELPGLSNSSTQTGCMLQTLYENGTISSEYEDSHLLFMFATGPGT
LHSADKLIRTPEDMKGMRIRRPSAVAGDIIESMGASPVGLPANDIYTSLQRGVVDGLSFPWEAITTFKLDELTKYHTNIP
FYSSALMMTMNKDKYESLPDDLKKVIDDNSGMALTKKVGEMWDRTDLLGLQAAKDRGDEIIDISDPLNDPDWKGPLLKGT
QKYLDDVSALGLDAESVYEKAKAASVACKV

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=208, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 38076; Mature: 38076

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAPFFSIGALAAISLFGCSGQSDNSSEVASNQEVTVLRFSHFYPATADVNKEIFEPWA
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
KKIGEDSNGRLKVEVYPSATLSKADTAYESTVKGTIDIGSQVQGYTSGRFPLTQIAELPG
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHCCC
LSNSSTQTGCMLQTLYENGTISSEYEDSHLLFMFATGPGTLHSADKLIRTPEDMKGMRIR
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCEEE
RPSAVAGDIIESMGASPVGLPANDIYTSLQRGVVDGLSFPWEAITTFKLDELTKYHTNIP
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHHHHHCCCC
FYSSALMMTMNKDKYESLPDDLKKVIDDNSGMALTKKVGEMWDRTDLLGLQAAKDRGDEI
CHHCEEEEEECCHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHCHHHHHHHHHHHCCCCEE
IDISDPLNDPDWKGPLLKGTQKYLDDVSALGLDAESVYEKAKAASVACKV
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MKLAPFFSIGALAAISLFGCSGQSDNSSEVASNQEVTVLRFSHFYPATADVNKEIFEPWA
CCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
KKIGEDSNGRLKVEVYPSATLSKADTAYESTVKGTIDIGSQVQGYTSGRFPLTQIAELPG
HHHCCCCCCEEEEEECCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCCCCCHHHHHHCCC
LSNSSTQTGCMLQTLYENGTISSEYEDSHLLFMFATGPGTLHSADKLIRTPEDMKGMRIR
CCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCEEE
RPSAVAGDIIESMGASPVGLPANDIYTSLQRGVVDGLSFPWEAITTFKLDELTKYHTNIP
CCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEHHHHHHHHCCCC
FYSSALMMTMNKDKYESLPDDLKKVIDDNSGMALTKKVGEMWDRTDLLGLQAAKDRGDEI
CHHCEEEEEECCHHHHCCHHHHHHHHCCCCCEEHHHHHHHHHCHHHHHHHHHHHCCCCEE
IDISDPLNDPDWKGPLLKGTQKYLDDVSALGLDAESVYEKAKAASVACKV
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA