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The map label for this gene is yiaY [H]

Identifier: 93005735

GI number: 93005735

Start: 1073650

End: 1074813

Strand: Reverse

Name: yiaY [H]

Synonym: Pcryo_0907

Alternate gene names: 93005735

Gene position: 1074813-1073650 (Counterclockwise)

Preceding gene: 93005738

Following gene: 93005734

Centisome position: 35.13

GC content: 44.5

Gene sequence:

>1164_bases
ATGACAGGGATGGAGTTTTATACTAATGGACACATTGTTAGCGAAGCTGACAGTATGCGCCAGAAGCTAGGGGATTTAGC
AAAACAGTACGACGCGACATCTGCCATTATTATTACAGATACTGGCATTTGTGAGCTGGGATACGTCGATATCGCACAAG
AGTCTTTAGAGCAGGCTGGTATTAATGTTGTTATTTTCGACAGGGTTGTTGCTGATCCGCCTATTGAAGTCGTCGAAGAA
GCTATTGAACTTGCCAGAGCGAACCAGTGTAATCTGGTCATCGGTTTAGGAGGTGGCAGCCCTATCGATACCGCGAAAAT
TGTCGCGCTATATCCCAATGACTTTCAATCGGTTAATGAGCTGTTAGAGGCAGATATTAGTGGTTTTAAAAAAATGCCGT
TGTTTGCGATCCCCACCACTGCAGGTACTGGCGCAGAGGCTACCTTTGTATCTGTAATCACAGCAAAGGATGGCAGCAAG
AAAGCCATATACACGCCTAAAATCCTACCTGATGTCGCGATTTTAGATGCGACGCTAACTCTCAAGCTTCCTCGCCATAT
TACTGCTGCCACTGCCTTAGATGCGATGGTTCACTGCATTGAAGCTTACACAAGCCGCACCAAAAAGAACCCCATTTCAG
ATGCGTTGGCTGTTAAAGGTTTGCAAATGCTATGGAGTAACTTTTATACAGTGCTCCATCACGGCGATGATATTGATGCT
CGTGCTGATATGTTATTGGGTTCAACGCTAGCTGGTATCGCTTTTGTCAATGCTTCCGTAGCAGCTGTACATGGACTCTC
CTACCCACTTAGCATTAACTTCCATGTGCCGCATGGGCATGCTAATGCGCTCGTGATGTGCAGTGTATTTACTTTCAACT
TACCAGTAGCAGCACCTCCTTATGCAGAACTCGCGCGTGCAGTGATGCCTATCGACACTTCGGGCATGACTGACATAGAG
GCTGCCCATCAATTTATTAATCAACTAAAGGACTTCTTGAAAACAAGTGGTCTAAAATATCGCTTAAATGAGCTAGATAT
AACGGGACAGGATATCCCCGCGTTAGCTGATATGGTCATTAATACCTATGCTCGTCTCATTGAAACCAATCCAATGGATA
TGTCTTTAGAGGAAGTAAAAATGATCTACCAAGAAATACTCTAA

Upstream 100 bases:

>100_bases
TGTAGCGTGATTGAGTTAATACTAAAACTTTATACACGCGATTTATCTAAAGGCTATAAATACACAAAAATAATCGCTCA
TCTACACAAGGAAGAATAGA

Downstream 100 bases:

>100_bases
TAAGCAGCAAATTTCTTAAATAATTTTGTCTATAAATCAAGGAAGATAGTTATGTCAAAATATGAGTTAGACGTGGTAGT
TGATGGATTCCATTACCTAG

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTGMEFYTNGHIVSEADSMRQKLGDLAKQYDATSAIIITDTGICELGYVDIAQESLEQAGINVVIFDRVVADPPIEVVEE
AIELARANQCNLVIGLGGGSPIDTAKIVALYPNDFQSVNELLEADISGFKKMPLFAIPTTAGTGAEATFVSVITAKDGSK
KAIYTPKILPDVAILDATLTLKLPRHITAATALDAMVHCIEAYTSRTKKNPISDALAVKGLQMLWSNFYTVLHHGDDIDA
RADMLLGSTLAGIAFVNASVAAVHGLSYPLSINFHVPHGHANALVMCSVFTFNLPVAAPPYAELARAVMPIDTSGMTDIE
AAHQFINQLKDFLKTSGLKYRLNELDITGQDIPALADMVINTYARLIETNPMDMSLEEVKMIYQEIL

Sequences:

>Translated_387_residues
MTGMEFYTNGHIVSEADSMRQKLGDLAKQYDATSAIIITDTGICELGYVDIAQESLEQAGINVVIFDRVVADPPIEVVEE
AIELARANQCNLVIGLGGGSPIDTAKIVALYPNDFQSVNELLEADISGFKKMPLFAIPTTAGTGAEATFVSVITAKDGSK
KAIYTPKILPDVAILDATLTLKLPRHITAATALDAMVHCIEAYTSRTKKNPISDALAVKGLQMLWSNFYTVLHHGDDIDA
RADMLLGSTLAGIAFVNASVAAVHGLSYPLSINFHVPHGHANALVMCSVFTFNLPVAAPPYAELARAVMPIDTSGMTDIE
AAHQFINQLKDFLKTSGLKYRLNELDITGQDIPALADMVINTYARLIETNPMDMSLEEVKMIYQEIL
>Mature_386_residues
TGMEFYTNGHIVSEADSMRQKLGDLAKQYDATSAIIITDTGICELGYVDIAQESLEQAGINVVIFDRVVADPPIEVVEEA
IELARANQCNLVIGLGGGSPIDTAKIVALYPNDFQSVNELLEADISGFKKMPLFAIPTTAGTGAEATFVSVITAKDGSKK
AIYTPKILPDVAILDATLTLKLPRHITAATALDAMVHCIEAYTSRTKKNPISDALAVKGLQMLWSNFYTVLHHGDDIDAR
ADMLLGSTLAGIAFVNASVAAVHGLSYPLSINFHVPHGHANALVMCSVFTFNLPVAAPPYAELARAVMPIDTSGMTDIEA
AHQFINQLKDFLKTSGLKYRLNELDITGQDIPALADMVINTYARLIETNPMDMSLEEVKMIYQEIL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=402, Percent_Identity=28.1094527363184, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI48994951, Length=385, Percent_Identity=33.5064935064935, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789163, Length=365, Percent_Identity=31.5068493150685, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI87082107, Length=362, Percent_Identity=33.1491712707182, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787493, Length=272, Percent_Identity=35.6617647058824, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI1789386, Length=365, Percent_Identity=25.4794520547945, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17537053, Length=413, Percent_Identity=26.3922518159806, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=385, Percent_Identity=32.987012987013, Blast_Score=187, Evalue=3e-48,
Organism=Drosophila melanogaster, GI24657991, Length=401, Percent_Identity=28.1795511221945, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41788; Mature: 41656

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00913 ADH_IRON_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGMEFYTNGHIVSEADSMRQKLGDLAKQYDATSAIIITDTGICELGYVDIAQESLEQAG
CCCCEEEECCCEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCHHHHHHHHHHHCC
INVVIFDRVVADPPIEVVEEAIELARANQCNLVIGLGGGSPIDTAKIVALYPNDFQSVNE
CEEEEEECHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHH
LLEADISGFKKMPLFAIPTTAGTGAEATFVSVITAKDGSKKAIYTPKILPDVAILDATLT
HHHHHHHCHHCCCEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCCCCCCEEEEEEEE
LKLPRHITAATALDAMVHCIEAYTSRTKKNPISDALAVKGLQMLWSNFYTVLHHGDDIDA
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RADMLLGSTLAGIAFVNASVAAVHGLSYPLSINFHVPHGHANALVMCSVFTFNLPVAAPP
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCC
YAELARAVMPIDTSGMTDIEAAHQFINQLKDFLKTSGLKYRLNELDITGQDIPALADMVI
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHH
NTYARLIETNPMDMSLEEVKMIYQEIL
HHHHHHHCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TGMEFYTNGHIVSEADSMRQKLGDLAKQYDATSAIIITDTGICELGYVDIAQESLEQAG
CCCEEEECCCEECCHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCHHHHHHHHHHHCC
INVVIFDRVVADPPIEVVEEAIELARANQCNLVIGLGGGSPIDTAKIVALYPNDFQSVNE
CEEEEEECHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEECCCCHHHHHH
LLEADISGFKKMPLFAIPTTAGTGAEATFVSVITAKDGSKKAIYTPKILPDVAILDATLT
HHHHHHHCHHCCCEEEECCCCCCCCCEEEEEEEEECCCCCCEEECCCCCCCCEEEEEEEE
LKLPRHITAATALDAMVHCIEAYTSRTKKNPISDALAVKGLQMLWSNFYTVLHHGDDIDA
EECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
RADMLLGSTLAGIAFVNASVAAVHGLSYPLSINFHVPHGHANALVMCSVFTFNLPVAAPP
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCC
YAELARAVMPIDTSGMTDIEAAHQFINQLKDFLKTSGLKYRLNELDITGQDIPALADMVI
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHH
NTYARLIETNPMDMSLEEVKMIYQEIL
HHHHHHHCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]