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The map label for this gene is betT [H]

Identifier: 93005703

GI number: 93005703

Start: 1035779

End: 1037824

Strand: Direct

Name: betT [H]

Synonym: Pcryo_0875

Alternate gene names: 93005703

Gene position: 1035779-1037824 (Clockwise)

Preceding gene: 93005702

Following gene: 93005704

Centisome position: 33.85

GC content: 44.57

Gene sequence:

>2046_bases
ATGTACAGCTCGCCATCAAAGGATGCGACGAAACCCCTGACTCTAAATAAGACGGTTTTTTTAGGTTCAGCTATTATTTC
TATTTTATTGATAATCTGGACGATTGCGTTTCCAGATTATAGTGAGGCATTATTAAGTTCAAGTATGGCATGGGTATCAG
AGAGTTTTGGCTGGTATTACATGCTGGTGGTTGCCGCGTATAGTATATTTGCCTTGTTTGTTGGCTTTTCTAAGTATGGC
GATATTAAGCTTGGTCAAGATCATGAAAAGGCGCAATTTCCCTTTTTAGCGTGGGCAGCGATGCTGTTCTCCGCTGGTAT
CGGCATTGATTTATTGTTTTTTGGTGCGTCTGAGCCGTTGATGCATTATCTGACGCCGCATACGGGGCTCGAGCCTGCCA
GTGAGGCGGCTATGCGTGAAGCACTTGCGCAGACCTTTTTACATTGGGGTCTACATGGCTGGGGCATTTATGCTTTAATC
GGGATGGCATTGGCGTACTTTGCTTATCGTAAAAACATGCCACTCGCGTTACGTTCACCACTGACGCCTATCTTTGGCGA
GCGCTTAATTAAAGGCTGGCTTGGTGATGGTATTGATACCTTTGGTGTGGTTTGTACCTTGATGGGTATCGCGACCAGTT
TGGGTATTGGTGTATTGCAAGCCAATGCTGGTTTGACTCATGTTTTTGGGATTGAATCCAGCAAAATGGTTCAAACCTTT
ATCATCATAGGTGTTGTCGCTGCCGCGGCGATCTCTGCGATGACTGGTGTAGAAAGAGGCGTCCGCCGTTTATCCGAATT
TAATATGCTATCTTCGATATTGCTATTAATCGCGATATTGGTGATGGGTAACACGGTTTATTTGCTGAATACCTTTACCC
AAAATATTGGTCAATACTTCCAAACCATCGTTTTCAAAACCTTTGATGTTTATGCTTATGATGGTCAAGCTGGCGCTGAT
TGGAAATCAGGCTGGACGATATTTTTCTGGGCATGGTGGGTCGCTTGGGCACCGTTTGTAGGCCTATTTATTGCGCGTAT
TAGCCGTGGTCGTACCCTGCGTGAGTTCGTATTTGGTGTGATGTTTATCCCACTTGGATTCATCTTTGCTTGGTTCTCTA
TCTTTGGTAACTCAGCGATAGATTTGGTTGCCAATGGTGCCACTGAACTTGGTGAAATCGCAGTCAATGATGCGGCAATG
GGCATGTTTGCCTTGTTTGAGTATTTTCCTTACAGCGAAGTGCTATCATTTGCAGGTGTGGTTATCGGGTTAGTATTCTT
TGTGACTTCAGCTGACTCAGGCGCGTTAGTATTAGCAAACTTGAGCTCACGCGGCATGACCAATGATACGGACGCACCTG
TTTGGTTACGCTTATTTTGGGCAGCAGCGACCGGTCTTATTACCCTAGGCTTATTGTTTGCTGGTGGTTTTGCCTCATTA
CAGTCAGTATCCGTCATTGCAGGTTTGCCGTTCTCTCTTATCCTTGTACTCTATATGATGTCGATGTGGAAGTCGTTAAA
AGAGGAAGGTAATAAGCGTAAAGCCAGTACGATTGGTACGGCTAATGTGCTTGATAGTGGTAAAAGCTGGAAAGCACGCT
TGCAACGTATCGTCAGTTTCCCAAGCCATGCACAAGTTGAACGGTTTTTACAAAATGTGGTCAGACCTGCCATGACGGAA
GTTGAAAAAGAGTTTGCGGCAGGCGGTCTAAAGACGTCTTTGGATATCCGTAACCCTGAACATATCGGACAAGATATAGA
TGAAGGCATGGATGAGAGTAGCGGTCAAATAGATGGTCTCAAATTGCGCGTCGGACATGGCGATGAAGATGACTTTATTT
ATGAAGTTAATTTGATCAAAGCGGAGCGTCCTAACTTTACATTGAGCACCTCAACTAAGAACGCAGAGTACTATTATCGT
GCGGAAGTGTTCTTAAGTGAAGGCTCGCAAGAGTATGACTTGGTTGGTTACTCCAAAGAGCAAGTGTTGGTCGATATCTT
AAATCAGTACGAGCGCCATTTGCAGTATCTACATTTAGAGCGTTAA

Upstream 100 bases:

>100_bases
GCGTCATGCAGGTATTTGTATGTCATGCGGTTATCAGTCATAAGATTATGACGGACAAAGCAATATCAGACCCTGTTTAA
TTTACCTATTGAGGTCTTTT

Downstream 100 bases:

>100_bases
TAGCTAAGTAATATACTCGACTTTACACTGACCCTATAAGTTGCATACAGCTTATAGGGTTTTTTAAATGTCAGCGTTAT
AGTCTATTTGCTATAAAAGG

Product: choline/carnitine/betaine transport protein

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 681; Mature: 681

Protein sequence:

>681_residues
MYSSPSKDATKPLTLNKTVFLGSAIISILLIIWTIAFPDYSEALLSSSMAWVSESFGWYYMLVVAAYSIFALFVGFSKYG
DIKLGQDHEKAQFPFLAWAAMLFSAGIGIDLLFFGASEPLMHYLTPHTGLEPASEAAMREALAQTFLHWGLHGWGIYALI
GMALAYFAYRKNMPLALRSPLTPIFGERLIKGWLGDGIDTFGVVCTLMGIATSLGIGVLQANAGLTHVFGIESSKMVQTF
IIIGVVAAAAISAMTGVERGVRRLSEFNMLSSILLLIAILVMGNTVYLLNTFTQNIGQYFQTIVFKTFDVYAYDGQAGAD
WKSGWTIFFWAWWVAWAPFVGLFIARISRGRTLREFVFGVMFIPLGFIFAWFSIFGNSAIDLVANGATELGEIAVNDAAM
GMFALFEYFPYSEVLSFAGVVIGLVFFVTSADSGALVLANLSSRGMTNDTDAPVWLRLFWAAATGLITLGLLFAGGFASL
QSVSVIAGLPFSLILVLYMMSMWKSLKEEGNKRKASTIGTANVLDSGKSWKARLQRIVSFPSHAQVERFLQNVVRPAMTE
VEKEFAAGGLKTSLDIRNPEHIGQDIDEGMDESSGQIDGLKLRVGHGDEDDFIYEVNLIKAERPNFTLSTSTKNAEYYYR
AEVFLSEGSQEYDLVGYSKEQVLVDILNQYERHLQYLHLER

Sequences:

>Translated_681_residues
MYSSPSKDATKPLTLNKTVFLGSAIISILLIIWTIAFPDYSEALLSSSMAWVSESFGWYYMLVVAAYSIFALFVGFSKYG
DIKLGQDHEKAQFPFLAWAAMLFSAGIGIDLLFFGASEPLMHYLTPHTGLEPASEAAMREALAQTFLHWGLHGWGIYALI
GMALAYFAYRKNMPLALRSPLTPIFGERLIKGWLGDGIDTFGVVCTLMGIATSLGIGVLQANAGLTHVFGIESSKMVQTF
IIIGVVAAAAISAMTGVERGVRRLSEFNMLSSILLLIAILVMGNTVYLLNTFTQNIGQYFQTIVFKTFDVYAYDGQAGAD
WKSGWTIFFWAWWVAWAPFVGLFIARISRGRTLREFVFGVMFIPLGFIFAWFSIFGNSAIDLVANGATELGEIAVNDAAM
GMFALFEYFPYSEVLSFAGVVIGLVFFVTSADSGALVLANLSSRGMTNDTDAPVWLRLFWAAATGLITLGLLFAGGFASL
QSVSVIAGLPFSLILVLYMMSMWKSLKEEGNKRKASTIGTANVLDSGKSWKARLQRIVSFPSHAQVERFLQNVVRPAMTE
VEKEFAAGGLKTSLDIRNPEHIGQDIDEGMDESSGQIDGLKLRVGHGDEDDFIYEVNLIKAERPNFTLSTSTKNAEYYYR
AEVFLSEGSQEYDLVGYSKEQVLVDILNQYERHLQYLHLER
>Mature_681_residues
MYSSPSKDATKPLTLNKTVFLGSAIISILLIIWTIAFPDYSEALLSSSMAWVSESFGWYYMLVVAAYSIFALFVGFSKYG
DIKLGQDHEKAQFPFLAWAAMLFSAGIGIDLLFFGASEPLMHYLTPHTGLEPASEAAMREALAQTFLHWGLHGWGIYALI
GMALAYFAYRKNMPLALRSPLTPIFGERLIKGWLGDGIDTFGVVCTLMGIATSLGIGVLQANAGLTHVFGIESSKMVQTF
IIIGVVAAAAISAMTGVERGVRRLSEFNMLSSILLLIAILVMGNTVYLLNTFTQNIGQYFQTIVFKTFDVYAYDGQAGAD
WKSGWTIFFWAWWVAWAPFVGLFIARISRGRTLREFVFGVMFIPLGFIFAWFSIFGNSAIDLVANGATELGEIAVNDAAM
GMFALFEYFPYSEVLSFAGVVIGLVFFVTSADSGALVLANLSSRGMTNDTDAPVWLRLFWAAATGLITLGLLFAGGFASL
QSVSVIAGLPFSLILVLYMMSMWKSLKEEGNKRKASTIGTANVLDSGKSWKARLQRIVSFPSHAQVERFLQNVVRPAMTE
VEKEFAAGGLKTSLDIRNPEHIGQDIDEGMDESSGQIDGLKLRVGHGDEDDFIYEVNLIKAERPNFTLSTSTKNAEYYYR
AEVFLSEGSQEYDLVGYSKEQVLVDILNQYERHLQYLHLER

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=681, Percent_Identity=43.0249632892805, Blast_Score=554, Evalue=1e-159,
Organism=Escherichia coli, GI1786224, Length=512, Percent_Identity=26.7578125, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1788102, Length=450, Percent_Identity=27.7777777777778, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 75185; Mature: 75185

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSSPSKDATKPLTLNKTVFLGSAIISILLIIWTIAFPDYSEALLSSSMAWVSESFGWYY
CCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
MLVVAAYSIFALFVGFSKYGDIKLGQDHEKAQFPFLAWAAMLFSAGIGIDLLFFGASEPL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCEEEEEECCCCHH
MHYLTPHTGLEPASEAAMREALAQTFLHWGLHGWGIYALIGMALAYFAYRKNMPLALRSP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCCC
LTPIFGERLIKGWLGDGIDTFGVVCTLMGIATSLGIGVLQANAGLTHVFGIESSKMVQTF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHEECCCCCEEEECCCCHHHHHHH
IIIGVVAAAAISAMTGVERGVRRLSEFNMLSSILLLIAILVMGNTVYLLNTFTQNIGQYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
QTIVFKTFDVYAYDGQAGADWKSGWTIFFWAWWVAWAPFVGLFIARISRGRTLREFVFGV
HHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MFIPLGFIFAWFSIFGNSAIDLVANGATELGEIAVNDAAMGMFALFEYFPYSEVLSFAGV
HHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VIGLVFFVTSADSGALVLANLSSRGMTNDTDAPVWLRLFWAAATGLITLGLLFAGGFASL
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QSVSVIAGLPFSLILVLYMMSMWKSLKEEGNKRKASTIGTANVLDSGKSWKARLQRIVSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCHHHHHHHHHHHCC
PSHAQVERFLQNVVRPAMTEVEKEFAAGGLKTSLDIRNPEHIGQDIDEGMDESSGQIDGL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHCCHHHHCCCCCCCCCCCE
KLRVGHGDEDDFIYEVNLIKAERPNFTLSTSTKNAEYYYRAEVFLSEGSQEYDLVGYSKE
EEEECCCCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEEEEEECCCCCCEEECCCHH
QVLVDILNQYERHLQYLHLER
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYSSPSKDATKPLTLNKTVFLGSAIISILLIIWTIAFPDYSEALLSSSMAWVSESFGWYY
CCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHH
MLVVAAYSIFALFVGFSKYGDIKLGQDHEKAQFPFLAWAAMLFSAGIGIDLLFFGASEPL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCHHHHHHHHHHHCCCCEEEEEECCCCHH
MHYLTPHTGLEPASEAAMREALAQTFLHWGLHGWGIYALIGMALAYFAYRKNMPLALRSP
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEECCCC
LTPIFGERLIKGWLGDGIDTFGVVCTLMGIATSLGIGVLQANAGLTHVFGIESSKMVQTF
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHEECCCCCEEEECCCCHHHHHHH
IIIGVVAAAAISAMTGVERGVRRLSEFNMLSSILLLIAILVMGNTVYLLNTFTQNIGQYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
QTIVFKTFDVYAYDGQAGADWKSGWTIFFWAWWVAWAPFVGLFIARISRGRTLREFVFGV
HHHHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
MFIPLGFIFAWFSIFGNSAIDLVANGATELGEIAVNDAAMGMFALFEYFPYSEVLSFAGV
HHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VIGLVFFVTSADSGALVLANLSSRGMTNDTDAPVWLRLFWAAATGLITLGLLFAGGFASL
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
QSVSVIAGLPFSLILVLYMMSMWKSLKEEGNKRKASTIGTANVLDSGKSWKARLQRIVSF
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHCCCHHHHHHHHHHHCC
PSHAQVERFLQNVVRPAMTEVEKEFAAGGLKTSLDIRNPEHIGQDIDEGMDESSGQIDGL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHCCHHHHCCCCCCCCCCCE
KLRVGHGDEDDFIYEVNLIKAERPNFTLSTSTKNAEYYYRAEVFLSEGSQEYDLVGYSKE
EEEECCCCCCCEEEEEEEEEECCCCEEEECCCCCCCEEEEEEEEEECCCCCCEEECCCHH
QVLVDILNQYERHLQYLHLER
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]