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The map label for this gene is ldcA [H]

Identifier: 93005687

GI number: 93005687

Start: 1015748

End: 1016962

Strand: Direct

Name: ldcA [H]

Synonym: Pcryo_0859

Alternate gene names: 93005687

Gene position: 1015748-1016962 (Clockwise)

Preceding gene: 93005685

Following gene: 93005689

Centisome position: 33.2

GC content: 49.05

Gene sequence:

>1215_bases
ATGACCAAGATATCTTCTGGACTTAATCGTCGCCAATTTTTATGTCAAGTCGGAATCAGCGTAGGGGCAGGGCTGTTAGC
GACCCAAAGCATCACTCAAGCGCTGGCTTCTAATACGACTGAGCAAGATAACAGCACGCAACTGACCAAAGATGATCTGC
CATCAGGACAAGCACAACAAGCAGCGCCCGAAACATTGCAGGCGCAAACGAGTTGTATCACGCCAAATATTGAGACGCGG
CTTTTTGCCAGCTCCAACGTCGGTGGTAGTGACGAGCGTAATGAATTGGCGTTAGATCGCATGGCTTGTGCGGGCTTTAA
AGTCGACAATCCTACGATTACCAAACGGCAGTATTTGCGCTTTGCAGGTACGGATTCGCAGCGCGCTAGCGATTTGCAAA
ACATCGCTACAGGTGCAATTAAAGCACCTAAACTGCTACTTGGTGTACGTGGTGGCTATGGTGCCGTGCGTTTATTGCCG
ATGGTGGATTGGTCGACGCTTGGTCGTATTATGAAGGAGCGTGGCACGATACTGGCGGGCTTTAGCGATGTGACCGCGAT
TCAGTGTGCGCTACTGGCAAAAGGAGGCATGAGCTCGCTTGCGGCACCGATGCTTTATAGTGAGTTTGGCAAAACCAAAC
CCGACCAAGTCAGCTGTCGACAATTTGCGGAAGCATTAACCAATCCAAATCTGGCTATCAATATACCAGACGCCTCTTTA
ACCAGTCCGAATTTACCGAGTATCTTGGCAAGCTCTGAGCCAAAAACGATAACGGGCACTATGTGGGGTGGCAATCTAAG
CGTGGTGTCAGCGCTGGCAGGCAGTGAGTATTTGCCACGAATTGCTGGCGGTATCGTATTTTTAGAAGATGTCGGTGAGC
AAGCCTATCGTATTGAGCGCATGCTGTATGATTTGTATTTAGCAGGCGTATTTAAAGATCAGCAAGCCATCGTATTTGGC
GCGCTATCGGGTAGCGGTGAGGATAGCTATGACAAGCGTTATGATGTCGCCACCGTAATTCGTCAATTGCATAAGCTGAC
AGGATTGCCGATTTATAGCGGTATGCGCTTTGGTCATATTGGTCAGAAACACAGCTTTCCACTGGGGGCGACGTGCCAGC
TTAGCGCCAATACAGTCGGTGGCTATCAATTGGTATTTAACGATTACCCAACGATTAAAGCCGATGCCATTCATGTAGAA
GGCTTGTGGCAATAA

Upstream 100 bases:

>100_bases
TTAGCGCATGTTAAATGAAATCGCGTGCATTTAAAGCATCAATGCTAAATAAGTATCCTTGTTAAACAAGCATTAACTGA
ATAGTACAAAAGGTAAAATA

Downstream 100 bases:

>100_bases
AATTTAGGTCTATAGTCGAATCTAAATAAATCAGATACGTAACTATCAAGTCGCTCAATGAAAAGTTGTATCGTTTTTAT
ATCGAATTAATTATATAAAA

Product: twin-arginine translocation pathway signal protein

Products: NA

Alternate protein names: LD-carboxypeptidase A; Muramoyltetrapeptide carboxypeptidase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTKISSGLNRRQFLCQVGISVGAGLLATQSITQALASNTTEQDNSTQLTKDDLPSGQAQQAAPETLQAQTSCITPNIETR
LFASSNVGGSDERNELALDRMACAGFKVDNPTITKRQYLRFAGTDSQRASDLQNIATGAIKAPKLLLGVRGGYGAVRLLP
MVDWSTLGRIMKERGTILAGFSDVTAIQCALLAKGGMSSLAAPMLYSEFGKTKPDQVSCRQFAEALTNPNLAINIPDASL
TSPNLPSILASSEPKTITGTMWGGNLSVVSALAGSEYLPRIAGGIVFLEDVGEQAYRIERMLYDLYLAGVFKDQQAIVFG
ALSGSGEDSYDKRYDVATVIRQLHKLTGLPIYSGMRFGHIGQKHSFPLGATCQLSANTVGGYQLVFNDYPTIKADAIHVE
GLWQ

Sequences:

>Translated_404_residues
MTKISSGLNRRQFLCQVGISVGAGLLATQSITQALASNTTEQDNSTQLTKDDLPSGQAQQAAPETLQAQTSCITPNIETR
LFASSNVGGSDERNELALDRMACAGFKVDNPTITKRQYLRFAGTDSQRASDLQNIATGAIKAPKLLLGVRGGYGAVRLLP
MVDWSTLGRIMKERGTILAGFSDVTAIQCALLAKGGMSSLAAPMLYSEFGKTKPDQVSCRQFAEALTNPNLAINIPDASL
TSPNLPSILASSEPKTITGTMWGGNLSVVSALAGSEYLPRIAGGIVFLEDVGEQAYRIERMLYDLYLAGVFKDQQAIVFG
ALSGSGEDSYDKRYDVATVIRQLHKLTGLPIYSGMRFGHIGQKHSFPLGATCQLSANTVGGYQLVFNDYPTIKADAIHVE
GLWQ
>Mature_403_residues
TKISSGLNRRQFLCQVGISVGAGLLATQSITQALASNTTEQDNSTQLTKDDLPSGQAQQAAPETLQAQTSCITPNIETRL
FASSNVGGSDERNELALDRMACAGFKVDNPTITKRQYLRFAGTDSQRASDLQNIATGAIKAPKLLLGVRGGYGAVRLLPM
VDWSTLGRIMKERGTILAGFSDVTAIQCALLAKGGMSSLAAPMLYSEFGKTKPDQVSCRQFAEALTNPNLAINIPDASLT
SPNLPSILASSEPKTITGTMWGGNLSVVSALAGSEYLPRIAGGIVFLEDVGEQAYRIERMLYDLYLAGVFKDQQAIVFGA
LSGSGEDSYDKRYDVATVIRQLHKLTGLPIYSGMRFGHIGQKHSFPLGATCQLSANTVGGYQLVFNDYPTIKADAIHVEG
LWQ

Specific function: Releases the terminal D-alanine residue from the cytoplasmic tetrapeptide recycling product L-Ala-gamma-D-Glu-meso- Dap-D-Ala. Can also cleave D-Ala from murein derivatives containing the tetrapeptide, i.e. MurNAc-tetrapeptide, UDP-MurNAc- tetrapeptide, G

COG id: COG1619

COG function: function code V; Uncharacterized proteins, homologs of microcin C7 resistance protein MccF

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S66 family [H]

Homologues:

Organism=Escherichia coli, GI1787441, Length=297, Percent_Identity=36.7003367003367, Blast_Score=196, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003507 [H]

Pfam domain/function: PF02016 Peptidase_S66 [H]

EC number: NA

Molecular weight: Translated: 43242; Mature: 43111

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKISSGLNRRQFLCQVGISVGAGLLATQSITQALASNTTEQDNSTQLTKDDLPSGQAQQ
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
AAPETLQAQTSCITPNIETRLFASSNVGGSDERNELALDRMACAGFKVDNPTITKRQYLR
CCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEECCCCCCCHHHHHE
FAGTDSQRASDLQNIATGAIKAPKLLLGVRGGYGAVRLLPMVDWSTLGRIMKERGTILAG
ECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEC
FSDVTAIQCALLAKGGMSSLAAPMLYSEFGKTKPDQVSCRQFAEALTNPNLAINIPDASL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
TSPNLPSILASSEPKTITGTMWGGNLSVVSALAGSEYLPRIAGGIVFLEDVGEQAYRIER
CCCCCCHHHCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHCCEEEEHHHCHHHHHHHH
MLYDLYLAGVFKDQQAIVFGALSGSGEDSYDKRYDVATVIRQLHKLTGLPIYSGMRFGHI
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
GQKHSFPLGATCQLSANTVGGYQLVFNDYPTIKADAIHVEGLWQ
CCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEECEEEECCCCC
>Mature Secondary Structure 
TKISSGLNRRQFLCQVGISVGAGLLATQSITQALASNTTEQDNSTQLTKDDLPSGQAQQ
CCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHH
AAPETLQAQTSCITPNIETRLFASSNVGGSDERNELALDRMACAGFKVDNPTITKRQYLR
CCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCEECCCCCCCHHHHHE
FAGTDSQRASDLQNIATGAIKAPKLLLGVRGGYGAVRLLPMVDWSTLGRIMKERGTILAG
ECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEC
FSDVTAIQCALLAKGGMSSLAAPMLYSEFGKTKPDQVSCRQFAEALTNPNLAINIPDASL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEECCCCCC
TSPNLPSILASSEPKTITGTMWGGNLSVVSALAGSEYLPRIAGGIVFLEDVGEQAYRIER
CCCCCCHHHCCCCCCEEEEEEECCCHHHHHHHHCCHHHHHHHCCEEEEHHHCHHHHHHHH
MLYDLYLAGVFKDQQAIVFGALSGSGEDSYDKRYDVATVIRQLHKLTGLPIYSGMRFGHI
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCCCCC
GQKHSFPLGATCQLSANTVGGYQLVFNDYPTIKADAIHVEGLWQ
CCCCCCCCCCEEEEECCCCCCEEEEECCCCCCEECEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]