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The map label for this gene is moaE [C]

Identifier: 93005537

GI number: 93005537

Start: 837213

End: 837704

Strand: Reverse

Name: moaE [C]

Synonym: Pcryo_0707

Alternate gene names: 93005537

Gene position: 837704-837213 (Counterclockwise)

Preceding gene: 93005538

Following gene: 93005536

Centisome position: 27.38

GC content: 45.33

Gene sequence:

>492_bases
ATGGCAGACCAAGTACATGGGCAGTCGATGAGCATTAAGCGTAGCATCGATGAGGCTTATCTCATCGCTGAACGTGATGG
CTTTGCGCTACTAGATTCAGACATTGATGAAAATCGACTAAAGAAAACCCTTGATGATGACAGCTGCGGCGCTTTCGTAT
GCTTTGAAGGTCGTGTACGTAATCACAATAATGCCAGTAGCGTCAACCGCTTGACCTACTATGGCTATGAAGAACTTGCA
CTCAATCAAGGACGTGCCATTATCGAAGAAGCCAAAAAGCGCTTTGAAATTACTCACGCTATTGCCATTCATCGTATCGG
GGCTTTAGAGATTGGTGATGTGGCGGTTTGGGTTGGGGTGGTTTCTGCCCATCGTTATCCTGCTTTTGATGCCTGCCGCT
GGATATTAGATACGATAAAAGCGGACATTCCCGTTTGGAAGCAAGAATACTACCAAGATGACTCTTCAAAATGGCTAAGC
AATAATGGGTAA

Upstream 100 bases:

>100_bases
GATAGCGTGGTTTTCATTACTCCAGTAGCAGGCGGTTAATAGTATTTAGACGCTTATTTGTATTGCTAAAAATTTTAAGA
ATAATAAATAGAGACAATAT

Downstream 100 bases:

>100_bases
GAATATAACAGTGTCATCACTGAGCTTAGCCTTGATTCTAACGGCTTGTACTAAAGAAAAAGGTACTGACTTGCCAGCTG
AGATCAACAATACCACTGAG

Product: molybdopterin biosynthesis MoaE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MADQVHGQSMSIKRSIDEAYLIAERDGFALLDSDIDENRLKKTLDDDSCGAFVCFEGRVRNHNNASSVNRLTYYGYEELA
LNQGRAIIEEAKKRFEITHAIAIHRIGALEIGDVAVWVGVVSAHRYPAFDACRWILDTIKADIPVWKQEYYQDDSSKWLS
NNG

Sequences:

>Translated_163_residues
MADQVHGQSMSIKRSIDEAYLIAERDGFALLDSDIDENRLKKTLDDDSCGAFVCFEGRVRNHNNASSVNRLTYYGYEELA
LNQGRAIIEEAKKRFEITHAIAIHRIGALEIGDVAVWVGVVSAHRYPAFDACRWILDTIKADIPVWKQEYYQDDSSKWLS
NNG
>Mature_162_residues
ADQVHGQSMSIKRSIDEAYLIAERDGFALLDSDIDENRLKKTLDDDSCGAFVCFEGRVRNHNNASSVNRLTYYGYEELAL
NQGRAIIEEAKKRFEITHAIAIHRIGALEIGDVAVWVGVVSAHRYPAFDACRWILDTIKADIPVWKQEYYQDDSSKWLSN
NG

Specific function: Converts Molybdopterin Precursor Z Into Molybdopterin. This Requires The Incorporation Of Two Sulfur Atoms Into Precursor Z To Generate A Dithiolene Group. [C]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0717 [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=114, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787003, Length=106, Percent_Identity=48.1132075471698, Blast_Score=91, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17509279, Length=139, Percent_Identity=30.2158273381295, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356259, Length=138, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 18498; Mature: 18367

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADQVHGQSMSIKRSIDEAYLIAERDGFALLDSDIDENRLKKTLDDDSCGAFVCFEGRVR
CCCCCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHCCCCCCCEEEEECCEEC
NHNNASSVNRLTYYGYEELALNQGRAIIEEAKKRFEITHAIAIHRIGALEIGDVAVWVGV
CCCCCHHHCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHH
VSAHRYPAFDACRWILDTIKADIPVWKQEYYQDDSSKWLSNNG
HHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ADQVHGQSMSIKRSIDEAYLIAERDGFALLDSDIDENRLKKTLDDDSCGAFVCFEGRVR
CCCCCCCCCHHHHHCCCEEEEECCCCCEEECCCCCHHHHHHHCCCCCCCEEEEECCEEC
NHNNASSVNRLTYYGYEELALNQGRAIIEEAKKRFEITHAIAIHRIGALEIGDVAVWVGV
CCCCCHHHCCEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECHHHHHHHH
VSAHRYPAFDACRWILDTIKADIPVWKQEYYQDDSSKWLSNNG
HHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]