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The map label for this gene is yfbQ [H]

Identifier: 93005522

GI number: 93005522

Start: 821833

End: 823470

Strand: Reverse

Name: yfbQ [H]

Synonym: Pcryo_0692

Alternate gene names: 93005522

Gene position: 823470-821833 (Counterclockwise)

Preceding gene: 93005525

Following gene: 93005519

Centisome position: 26.91

GC content: 45.73

Gene sequence:

>1638_bases
ATGACGGCTGATGACAAAACTAAAAGCACACAAGCTGAACGACTGGTACAGCTGCGCCGCGACAAAGGCATGACGGCAGA
GCAGCTGGCACAAGCGATGACTGCTGCTGGCGCTAAAGTCAGCCGCGGTGCTATCTCTAATTGGGAGCGTGGGACCAATG
GGATTGTCTCATCTAAGCTACCTACCCTTGCGCGACTCTTAGGTTGTAGCGAAGGGTACTTGTTGCGCGGTGAGCTTGAA
AGTGACAGCAAATCAGATGACGATTCTGACAGTATATCGTCTGATAACGATAAAGCTGTCGATGCAGGTGAGCAAGCTCA
TAGCACTAGTCAGAATACACCAACAACAACTACCTCTTCTACTCCCCGCAAAAATTCACCAAATAACCTGATGAGTGGTC
ACTCTATGAACTCAATAAAAAAATCTGATAAATTACAAAACGTCTGCTACGACATTCGCGGTCCTCTGCTGCAAACTGCC
AATAAAATGGAAGCCGAAGGCAAGCGTATCTTAAAGCTAAATATCGGCAACCCTGCTCCTTTTGGTTTAGAAGCACCGCA
TGAGATTTTGCGTGATGTGGCGATGAATCTGCCGGAAGCGACGGGCTACTCAGACTCGCAAGGGATTTTTTCAGCGCGTA
AAGCCGTATTGCAATATTACCAATCAAAGGGTCTGCTATCGGCAGTTGATGTTCGTGATGTCTATCTAGGTAATGGCGTC
TCTGAGCTGATTGTCATGACCATGCAAGCGCTGATGAATGATGGCGATGAAGTGCTGGTTCCGATGCCAGACTACCCACT
GTGGACGGCAGCTGCCAATCTCGCAGGCGGTACAGCGGTACATTATCGCTGTAATGAAGAAGACAATTGGCATCCTGATA
TTGAAGACATCAAATCCAAAATCACCAGCAAAACCAAAGGCATCGTAGTTATTAATCCCAATAATCCGACAGGCGCGCTG
TATAGTGATGAAGTACTGCTGCAAATCGTCGAGGTCGCAAAAGAGCATGATTTAATCATCATGGCGGATGAGATTTATGA
CCGTATTCTCTATGATGATATGGAACATACGCCGATGAGCACTTTGACCGATGAAGTACTGGTGTTGTCCTATAATGGTT
TATCAAAATCACATCGTATTGCAGGCTTTCGTGCCGGTTGGATGATGGTTTCAGGTCGTAAAGAACATGCGGCTGACTTT
ATCGAAGGTTTGGATATGCTTGCATCTATGCGCCTGTGTTCTAACGTTCAAGGACAATATGCGATTCAGACAGCGATGGG
TGGCTATCAAAGCATGAAGGACCTAACGTCTAAAAAAGGGCGCTTGTATAAGCAGCGCGAGTTGGCAGTGACCCGTCTTA
ATGCGATAAAAGGTATCTCTTGTACCATGCCACAAGGCGCGTTTTACTGCTTTCCAAAGATGGATCCTGAGATTTACCCT
ATCAAAGATGACATGCAGTTTATGATGGATTTATTGTTAGAAGAAAACGTATTGATGGTACAAGGCACAGGATTTAACTG
GGATAAAAATGACCATTTCCGCTTGGTGTTTTTACCCAACTTACACGACTTAGAAGACGCTATGGATCGCTTAGACCGCT
TCTTTGCTAAGAAGCGTAAGCAGTTTGGTACTGACTAA

Upstream 100 bases:

>100_bases
AAGTAGTTCTCTTTTAAAGCATTAGCTTAATACTTATCCAAGAGAGTTGGTTTCGTTATCTGATTAATGACAGATTCATA
AAATAAAAAAGGCTTACATA

Downstream 100 bases:

>100_bases
TATATAGATGACACCTATATTTTTCTATAAAAAAACGCTTACCGATATGATATCGATAAGCGTTTTCTATTTGTATTAAT
CAAAAATTAAATGACTTTGA

Product: bifunctional HTH-domain containing protein/aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTADDKTKSTQAERLVQLRRDKGMTAEQLAQAMTAAGAKVSRGAISNWERGTNGIVSSKLPTLARLLGCSEGYLLRGELE
SDSKSDDDSDSISSDNDKAVDAGEQAHSTSQNTPTTTTSSTPRKNSPNNLMSGHSMNSIKKSDKLQNVCYDIRGPLLQTA
NKMEAEGKRILKLNIGNPAPFGLEAPHEILRDVAMNLPEATGYSDSQGIFSARKAVLQYYQSKGLLSAVDVRDVYLGNGV
SELIVMTMQALMNDGDEVLVPMPDYPLWTAAANLAGGTAVHYRCNEEDNWHPDIEDIKSKITSKTKGIVVINPNNPTGAL
YSDEVLLQIVEVAKEHDLIIMADEIYDRILYDDMEHTPMSTLTDEVLVLSYNGLSKSHRIAGFRAGWMMVSGRKEHAADF
IEGLDMLASMRLCSNVQGQYAIQTAMGGYQSMKDLTSKKGRLYKQRELAVTRLNAIKGISCTMPQGAFYCFPKMDPEIYP
IKDDMQFMMDLLLEENVLMVQGTGFNWDKNDHFRLVFLPNLHDLEDAMDRLDRFFAKKRKQFGTD

Sequences:

>Translated_545_residues
MTADDKTKSTQAERLVQLRRDKGMTAEQLAQAMTAAGAKVSRGAISNWERGTNGIVSSKLPTLARLLGCSEGYLLRGELE
SDSKSDDDSDSISSDNDKAVDAGEQAHSTSQNTPTTTTSSTPRKNSPNNLMSGHSMNSIKKSDKLQNVCYDIRGPLLQTA
NKMEAEGKRILKLNIGNPAPFGLEAPHEILRDVAMNLPEATGYSDSQGIFSARKAVLQYYQSKGLLSAVDVRDVYLGNGV
SELIVMTMQALMNDGDEVLVPMPDYPLWTAAANLAGGTAVHYRCNEEDNWHPDIEDIKSKITSKTKGIVVINPNNPTGAL
YSDEVLLQIVEVAKEHDLIIMADEIYDRILYDDMEHTPMSTLTDEVLVLSYNGLSKSHRIAGFRAGWMMVSGRKEHAADF
IEGLDMLASMRLCSNVQGQYAIQTAMGGYQSMKDLTSKKGRLYKQRELAVTRLNAIKGISCTMPQGAFYCFPKMDPEIYP
IKDDMQFMMDLLLEENVLMVQGTGFNWDKNDHFRLVFLPNLHDLEDAMDRLDRFFAKKRKQFGTD
>Mature_544_residues
TADDKTKSTQAERLVQLRRDKGMTAEQLAQAMTAAGAKVSRGAISNWERGTNGIVSSKLPTLARLLGCSEGYLLRGELES
DSKSDDDSDSISSDNDKAVDAGEQAHSTSQNTPTTTTSSTPRKNSPNNLMSGHSMNSIKKSDKLQNVCYDIRGPLLQTAN
KMEAEGKRILKLNIGNPAPFGLEAPHEILRDVAMNLPEATGYSDSQGIFSARKAVLQYYQSKGLLSAVDVRDVYLGNGVS
ELIVMTMQALMNDGDEVLVPMPDYPLWTAAANLAGGTAVHYRCNEEDNWHPDIEDIKSKITSKTKGIVVINPNNPTGALY
SDEVLLQIVEVAKEHDLIIMADEIYDRILYDDMEHTPMSTLTDEVLVLSYNGLSKSHRIAGFRAGWMMVSGRKEHAADFI
EGLDMLASMRLCSNVQGQYAIQTAMGGYQSMKDLTSKKGRLYKQRELAVTRLNAIKGISCTMPQGAFYCFPKMDPEIYPI
KDDMQFMMDLLLEENVLMVQGTGFNWDKNDHFRLVFLPNLHDLEDAMDRLDRFFAKKRKQFGTD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=421, Percent_Identity=28.2660332541568, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI19263340, Length=486, Percent_Identity=26.1316872427983, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=27.9132791327913, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI4885351, Length=472, Percent_Identity=27.3305084745763, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI95147551, Length=227, Percent_Identity=25.9911894273128, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169881279, Length=227, Percent_Identity=25.9911894273128, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=169, Percent_Identity=27.2189349112426, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI56713256, Length=169, Percent_Identity=27.2189349112426, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI149944424, Length=371, Percent_Identity=23.7196765498652, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI169881281, Length=104, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1788627, Length=401, Percent_Identity=58.6034912718205, Blast_Score=530, Evalue=1e-151,
Organism=Escherichia coli, GI1788722, Length=400, Percent_Identity=26.5, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786816, Length=390, Percent_Identity=20.2564102564103, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=428, Percent_Identity=26.8691588785047, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71981209, Length=481, Percent_Identity=25.1559251559252, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71981215, Length=268, Percent_Identity=25.7462686567164, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=218, Percent_Identity=28.4403669724771, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994472, Length=143, Percent_Identity=33.5664335664336, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=143, Percent_Identity=33.5664335664336, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320317, Length=395, Percent_Identity=26.5822784810127, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323118, Length=379, Percent_Identity=27.9683377308707, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=404, Percent_Identity=24.2574257425743, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI18859735, Length=488, Percent_Identity=28.2786885245902, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24641770, Length=494, Percent_Identity=25.3036437246964, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641760, Length=494, Percent_Identity=25.3036437246964, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641768, Length=494, Percent_Identity=25.3036437246964, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641766, Length=494, Percent_Identity=25.3036437246964, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24641764, Length=494, Percent_Identity=25.3036437246964, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI45551451, Length=491, Percent_Identity=25.4582484725051, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573069, Length=264, Percent_Identity=23.8636363636364, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24646114, Length=264, Percent_Identity=23.8636363636364, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573067, Length=264, Percent_Identity=23.8636363636364, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28573065, Length=264, Percent_Identity=23.8636363636364, Blast_Score=80, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 60473; Mature: 60342

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS50943 HTH_CROC1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADDKTKSTQAERLVQLRRDKGMTAEQLAQAMTAAGAKVSRGAISNWERGTNGIVSSKL
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHH
PTLARLLGCSEGYLLRGELESDSKSDDDSDSISSDNDKAVDAGEQAHSTSQNTPTTTTSS
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCC
TPRKNSPNNLMSGHSMNSIKKSDKLQNVCYDIRGPLLQTANKMEAEGKRILKLNIGNPAP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCC
FGLEAPHEILRDVAMNLPEATGYSDSQGIFSARKAVLQYYQSKGLLSAVDVRDVYLGNGV
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCH
SELIVMTMQALMNDGDEVLVPMPDYPLWTAAANLAGGTAVHYRCNEEDNWHPDIEDIKSK
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHH
ITSKTKGIVVINPNNPTGALYSDEVLLQIVEVAKEHDLIIMADEIYDRILYDDMEHTPMS
HHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCHH
TLTDEVLVLSYNGLSKSHRIAGFRAGWMMVSGRKEHAADFIEGLDMLASMRLCSNVQGQY
HHCCCEEEEEECCCCCCCCCCEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
AIQTAMGGYQSMKDLTSKKGRLYKQRELAVTRLNAIKGISCTMPQGAFYCFPKMDPEIYP
EHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCCEEE
IKDDMQFMMDLLLEENVLMVQGTGFNWDKNDHFRLVFLPNLHDLEDAMDRLDRFFAKKRK
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
QFGTD
HCCCC
>Mature Secondary Structure 
TADDKTKSTQAERLVQLRRDKGMTAEQLAQAMTAAGAKVSRGAISNWERGTNGIVSSKL
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCHHHHH
PTLARLLGCSEGYLLRGELESDSKSDDDSDSISSDNDKAVDAGEQAHSTSQNTPTTTTSS
HHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCCC
TPRKNSPNNLMSGHSMNSIKKSDKLQNVCYDIRGPLLQTANKMEAEGKRILKLNIGNPAP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCCCC
FGLEAPHEILRDVAMNLPEATGYSDSQGIFSARKAVLQYYQSKGLLSAVDVRDVYLGNGV
CCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHCCCH
SELIVMTMQALMNDGDEVLVPMPDYPLWTAAANLAGGTAVHYRCNEEDNWHPDIEDIKSK
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHH
ITSKTKGIVVINPNNPTGALYSDEVLLQIVEVAKEHDLIIMADEIYDRILYDDMEHTPMS
HHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCHH
TLTDEVLVLSYNGLSKSHRIAGFRAGWMMVSGRKEHAADFIEGLDMLASMRLCSNVQGQY
HHCCCEEEEEECCCCCCCCCCEEEECEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
AIQTAMGGYQSMKDLTSKKGRLYKQRELAVTRLNAIKGISCTMPQGAFYCFPKMDPEIYP
EHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCCCEEE
IKDDMQFMMDLLLEENVLMVQGTGFNWDKNDHFRLVFLPNLHDLEDAMDRLDRFFAKKRK
CHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
QFGTD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]