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The map label for this gene is fbp [H]

Identifier: 93005360

GI number: 93005360

Start: 626340

End: 627323

Strand: Reverse

Name: fbp [H]

Synonym: Pcryo_0530

Alternate gene names: 93005360

Gene position: 627323-626340 (Counterclockwise)

Preceding gene: 93005364

Following gene: 93005359

Centisome position: 20.5

GC content: 44.0

Gene sequence:

>984_bases
ATGACAACCTTAGCACAGTATTTGAACACTAAAGCCACCACTCCTGCCCTCAATGACGTTATCACTACCGTTACTGACGT
CGGCAAGACCATCTCACAGCTCTTAAGAAAAGGCGCTTTGGCAGACATCCTTGGTGAAGCGGGTAATCAAAATGTGCAAG
GTGAAGACCAGAAGAAGTTAGATGTCTTAGCCAATGACTTATTGTTAGATGCATTGGCACAAAACAGCCATTGTGCTGGT
GTTGCTTCAGAAGAGCTTGACGACGCCACTCCTGCCAATGTTGATGGCAGTTTATTGGTATTGTTTGACCCACTCGATGG
CTCGTCTAATATCGACATCAATATGGCTGTCGGTACTATATTCTCTATTTTACCGTACCAGCGTCAAGGTCAAGTTAGTG
AAAATAGCGACTTTTTACAAGCGGGTAATCAGCAGCTAGCAGCCGGTTACTTACTATATGGCACCTCTACCGTTCTCACG
CTGACCATCACAGATAATGTAGTCATGTTTAGCCTAGATCCAGATACCAATGACTATGTATTGATAGAAGAAAATGTCAC
AATCGATGCCGATACTAGCGAATATGCTATCAATGCCTCAAACTACCGTTATTGGCGCGCGCCAATGCAGCAATATATCG
ATGAGCTTATCGCTGGCGAGACAGGCGTACGTGGTCGCGATTTTAATACGCGCTGGGTTGCCGCCATGGTTGGTGATGTT
CATCGCATTCTATGCCGCGGTGGTTTATTCACATATCCATTTGATACCAAATACGCCAATAAAGCAGGCAAATTACGTCT
CATGTATGAAGCCAATCCCATGAGTTTATTAATTGAACGTGCTAGCGGCGGGGCAACGGATGCAGTCAATCGCATTTTAG
ATATAGAGCCGATTGACATTCATCAACGCGTGCCTGTAGTACTTGGCAGTAAAAATGAAGTCGACTATATTAAAGAGTTG
CATTTAAACCATACTGATAAATAA

Upstream 100 bases:

>100_bases
ACAATATCTCTCATATCAATATAACGTAATCAATTCTTAAACACGCATTCCATACTTAGCTTGTACCACTCTTTATCAGA
ATTATTCATTAGGAAACACT

Downstream 100 bases:

>100_bases
GACATACAAGCACATTTTGACAGCACCTATAAAGCCATATCAATAATCATTTTATAGGCGCTGTCTATATTTTATACTTT
TTCTCTAAGCGATCTATTAT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTTLAQYLNTKATTPALNDVITTVTDVGKTISQLLRKGALADILGEAGNQNVQGEDQKKLDVLANDLLLDALAQNSHCAG
VASEELDDATPANVDGSLLVLFDPLDGSSNIDINMAVGTIFSILPYQRQGQVSENSDFLQAGNQQLAAGYLLYGTSTVLT
LTITDNVVMFSLDPDTNDYVLIEENVTIDADTSEYAINASNYRYWRAPMQQYIDELIAGETGVRGRDFNTRWVAAMVGDV
HRILCRGGLFTYPFDTKYANKAGKLRLMYEANPMSLLIERASGGATDAVNRILDIEPIDIHQRVPVVLGSKNEVDYIKEL
HLNHTDK

Sequences:

>Translated_327_residues
MTTLAQYLNTKATTPALNDVITTVTDVGKTISQLLRKGALADILGEAGNQNVQGEDQKKLDVLANDLLLDALAQNSHCAG
VASEELDDATPANVDGSLLVLFDPLDGSSNIDINMAVGTIFSILPYQRQGQVSENSDFLQAGNQQLAAGYLLYGTSTVLT
LTITDNVVMFSLDPDTNDYVLIEENVTIDADTSEYAINASNYRYWRAPMQQYIDELIAGETGVRGRDFNTRWVAAMVGDV
HRILCRGGLFTYPFDTKYANKAGKLRLMYEANPMSLLIERASGGATDAVNRILDIEPIDIHQRVPVVLGSKNEVDYIKEL
HLNHTDK
>Mature_326_residues
TTLAQYLNTKATTPALNDVITTVTDVGKTISQLLRKGALADILGEAGNQNVQGEDQKKLDVLANDLLLDALAQNSHCAGV
ASEELDDATPANVDGSLLVLFDPLDGSSNIDINMAVGTIFSILPYQRQGQVSENSDFLQAGNQQLAAGYLLYGTSTVLTL
TITDNVVMFSLDPDTNDYVLIEENVTIDADTSEYAINASNYRYWRAPMQQYIDELIAGETGVRGRDFNTRWVAAMVGDVH
RILCRGGLFTYPFDTKYANKAGKLRLMYEANPMSLLIERASGGATDAVNRILDIEPIDIHQRVPVVLGSKNEVDYIKELH
LNHTDK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI22907028, Length=335, Percent_Identity=39.1044776119403, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI189083692, Length=318, Percent_Identity=39.622641509434, Blast_Score=204, Evalue=7e-53,
Organism=Homo sapiens, GI16579888, Length=318, Percent_Identity=39.622641509434, Blast_Score=204, Evalue=7e-53,
Organism=Escherichia coli, GI1790679, Length=334, Percent_Identity=38.9221556886228, Blast_Score=221, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI17508131, Length=290, Percent_Identity=41.3793103448276, Blast_Score=218, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323409, Length=305, Percent_Identity=39.0163934426229, Blast_Score=204, Evalue=2e-53,
Organism=Drosophila melanogaster, GI19921562, Length=307, Percent_Identity=39.0879478827362, Blast_Score=201, Evalue=7e-52,
Organism=Drosophila melanogaster, GI45550998, Length=307, Percent_Identity=39.0879478827362, Blast_Score=201, Evalue=7e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 35779; Mature: 35647

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00659 GLYCOSYL_HYDROL_F5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLAQYLNTKATTPALNDVITTVTDVGKTISQLLRKGALADILGEAGNQNVQGEDQKKL
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
DVLANDLLLDALAQNSHCAGVASEELDDATPANVDGSLLVLFDPLDGSSNIDINMAVGTI
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEHHHHH
FSILPYQRQGQVSENSDFLQAGNQQLAAGYLLYGTSTVLTLTITDNVVMFSLDPDTNDYV
HHHCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCEEEEEEEECCEEEEEECCCCCCEE
LIEENVTIDADTSEYAINASNYRYWRAPMQQYIDELIAGETGVRGRDFNTRWVAAMVGDV
EEECCEEEECCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
HRILCRGGLFTYPFDTKYANKAGKLRLMYEANPMSLLIERASGGATDAVNRILDIEPIDI
HHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCC
HQRVPVVLGSKNEVDYIKELHLNHTDK
CCCCCEEECCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTLAQYLNTKATTPALNDVITTVTDVGKTISQLLRKGALADILGEAGNQNVQGEDQKKL
CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCHHHH
DVLANDLLLDALAQNSHCAGVASEELDDATPANVDGSLLVLFDPLDGSSNIDINMAVGTI
HHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEHHHHH
FSILPYQRQGQVSENSDFLQAGNQQLAAGYLLYGTSTVLTLTITDNVVMFSLDPDTNDYV
HHHCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEECCEEEEEEEECCEEEEEECCCCCCEE
LIEENVTIDADTSEYAINASNYRYWRAPMQQYIDELIAGETGVRGRDFNTRWVAAMVGDV
EEECCEEEECCCCCEEEECCCCEEEHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
HRILCRGGLFTYPFDTKYANKAGKLRLMYEANPMSLLIERASGGATDAVNRILDIEPIDI
HHHHHCCCEEECCCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCC
HQRVPVVLGSKNEVDYIKELHLNHTDK
CCCCCEEECCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA