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The map label for this gene is ycgM [H]

Identifier: 93005161

GI number: 93005161

Start: 398149

End: 398865

Strand: Direct

Name: ycgM [H]

Synonym: Pcryo_0330

Alternate gene names: 93005161

Gene position: 398149-398865 (Clockwise)

Preceding gene: 93005160

Following gene: 93005162

Centisome position: 13.01

GC content: 46.86

Gene sequence:

>717_bases
ATGAGCCAATCACCATCTATATCCTTAGTCGATACAATTGCTGCCAGCGTCAAGGATGACGCGAGTATTGCCACCATTAA
CGATAGCGTACGAGAATCCATTGGCAAGGTCATTTGCGTTGGCCGTAACTATGCAGAACACGCGCGTGAGCTTGGCAATG
AGATACCAAAATCGCCTATCTTATTCATGAAGCCAGCATCATCAGTGGTCAGTGTGCATAATGATATTGTCCGTCCAAAT
CCAGCGCTATATGGCGACACTCATTATGAAGCAGAGCTGTGTATTCAGCTGGCAGCCGACTTATCGGCAGCAACGATTGA
ACAAGCAAAGCAAGCGATAGGTGGCGTGACTTTGGGGCTTGATTTGACCCTACGTGACTTGCAAAGCAAGCTCAAAGAAA
AAGGTCATCCATGGGAGCGTGCTAAATGTTTCGATGGTGCTTGTGTGCTTGCCGATTGGATTGATCCGCAAGCGTTTGGT
GATTTTTGCCATGTTGAATATCAGCTCTATATCAATGACGAGCTGAAGCAAGATGGTGACAGTGCCTTGATGCTATTTCC
AGTGTATGAGCTACTAGCAGAGATTAGCCATGCCTTTAGCTTACAAGCAGGCGATGTGATTATGACAGGTACGCCAAGCG
GCGTTGGTGTATTGCAAGCAGCTGATACGCTAACATTCAAGCTTCGCACTCATGAATGGCAGGTGCAAGTTCGATAA

Upstream 100 bases:

>100_bases
TAATGATTTGTTATGAATAAAACCTATCATAAACGTTGTGATAAATAGTGCAGTATGTTTCGCTTTTTAAAATATCAATC
ATCTGTTGTGAGTGCCTAGT

Downstream 100 bases:

>100_bases
TTTCTTATCGCAGCAGTATCATATAAGTTTTTAAATGCATTAACGCTATCAAAAAATCCCAAGTTCACACTTGGGATTTT
TTTGGTTTATCAGTGGTAAT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSQSPSISLVDTIAASVKDDASIATINDSVRESIGKVICVGRNYAEHARELGNEIPKSPILFMKPASSVVSVHNDIVRPN
PALYGDTHYEAELCIQLAADLSAATIEQAKQAIGGVTLGLDLTLRDLQSKLKEKGHPWERAKCFDGACVLADWIDPQAFG
DFCHVEYQLYINDELKQDGDSALMLFPVYELLAEISHAFSLQAGDVIMTGTPSGVGVLQAADTLTFKLRTHEWQVQVR

Sequences:

>Translated_238_residues
MSQSPSISLVDTIAASVKDDASIATINDSVRESIGKVICVGRNYAEHARELGNEIPKSPILFMKPASSVVSVHNDIVRPN
PALYGDTHYEAELCIQLAADLSAATIEQAKQAIGGVTLGLDLTLRDLQSKLKEKGHPWERAKCFDGACVLADWIDPQAFG
DFCHVEYQLYINDELKQDGDSALMLFPVYELLAEISHAFSLQAGDVIMTGTPSGVGVLQAADTLTFKLRTHEWQVQVR
>Mature_237_residues
SQSPSISLVDTIAASVKDDASIATINDSVRESIGKVICVGRNYAEHARELGNEIPKSPILFMKPASSVVSVHNDIVRPNP
ALYGDTHYEAELCIQLAADLSAATIEQAKQAIGGVTLGLDLTLRDLQSKLKEKGHPWERAKCFDGACVLADWIDPQAFGD
FCHVEYQLYINDELKQDGDSALMLFPVYELLAEISHAFSLQAGDVIMTGTPSGVGVLQAADTLTFKLRTHEWQVQVR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=207, Percent_Identity=32.8502415458937, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI215422413, Length=188, Percent_Identity=34.0425531914894, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI66348062, Length=188, Percent_Identity=34.0425531914894, Blast_Score=134, Evalue=5e-32,
Organism=Homo sapiens, GI156231349, Length=185, Percent_Identity=32.972972972973, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI40786394, Length=185, Percent_Identity=31.8918918918919, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1787428, Length=205, Percent_Identity=41.4634146341463, Blast_Score=176, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17557057, Length=198, Percent_Identity=37.8787878787879, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324161, Length=217, Percent_Identity=35.4838709677419, Blast_Score=139, Evalue=4e-34,
Organism=Drosophila melanogaster, GI28571789, Length=189, Percent_Identity=29.6296296296296, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI28572127, Length=188, Percent_Identity=26.5957446808511, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 25942; Mature: 25810

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSPSISLVDTIAASVKDDASIATINDSVRESIGKVICVGRNYAEHARELGNEIPKSPI
CCCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCE
LFMKPASSVVSVHNDIVRPNPALYGDTHYEAELCIQLAADLSAATIEQAKQAIGGVTLGL
EEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
DLTLRDLQSKLKEKGHPWERAKCFDGACVLADWIDPQAFGDFCHVEYQLYINDELKQDGD
EHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCHHCCCEEEEEEEEEECCHHCCCCC
SALMLFPVYELLAEISHAFSLQAGDVIMTGTPSGVGVLQAADTLTFKLRTHEWQVQVR
CEEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCEEEEEEEEEEEEEEEC
>Mature Secondary Structure 
SQSPSISLVDTIAASVKDDASIATINDSVRESIGKVICVGRNYAEHARELGNEIPKSPI
CCCCCCHHHHHHHHHCCCCCEEEEECHHHHHHHCCEEEECCCHHHHHHHHHHHCCCCCE
LFMKPASSVVSVHNDIVRPNPALYGDTHYEAELCIQLAADLSAATIEQAKQAIGGVTLGL
EEECCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
DLTLRDLQSKLKEKGHPWERAKCFDGACVLADWIDPQAFGDFCHVEYQLYINDELKQDGD
EHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCHHCCCEEEEEEEEEECCHHCCCCC
SALMLFPVYELLAEISHAFSLQAGDVIMTGTPSGVGVLQAADTLTFKLRTHEWQVQVR
CEEEHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEECCEEEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]