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The map label for this gene is dsbC [H]

Identifier: 93005111

GI number: 93005111

Start: 334518

End: 335375

Strand: Reverse

Name: dsbC [H]

Synonym: Pcryo_0280

Alternate gene names: 93005111

Gene position: 335375-334518 (Counterclockwise)

Preceding gene: 93005113

Following gene: 93005110

Centisome position: 10.96

GC content: 46.15

Gene sequence:

>858_bases
ATGTTCTTAGCGCCTTTTTCTAAAACCAATCCCAACCGTGATACGTTTTCTCGCAGTCCTCTTACTCGTGTTATGAGTGC
TGCCTTGCTGGTTATCGTTGCAGCTGGCTGCTCTAACAATGCAGCAGATGCGACCAACAATACAGATCTTGTCAATAGCA
GCAAAGCCAAAACGAGTACTGCTGCGGTTTCTAAGGATAGCGATGCTAAAGTAGTAAAATCTTTGCAAGCCAATTTAAAG
GCTTCTGGTATTGAAGAGACTATCCTCTCAGCTGTACCAACCGATATGACTGGTATTTATTGGGTGACAGCTGAAGGATT
GCCTTCTTTTTTTACGGATAAGACGGGCAAGCATATTATTCAAGGGCAAATCATCGCGGTTGGTGCAGAAGCGCCTGTAG
ATATTAGTGCCGCGTTGTTGGCCAGTACTGCCCAAGAAGCGTTAAAAGCAGTCGACAAAAAAGACATGGTTATTTATCCA
GCAAAGGGCGCGACTAAAGCTGTGGTTTACGCCTTTACAGATGCAGATTGTGGTTATTGCCGTAAATTGCATGAAGAGAT
GGATGATATTAATACACGTGGCATCGAGGTACGTTATTTGGCATGGCCACGTAGCCAAGAATCAGTGCCAAAAATGGAAG
CTATTTGGTGTAGTCAAGATCGTAAGGCGGCAATGAATCAAGGGAAAGCTGGCGCCGATGTGCAAGCGCCTAGCTGTGCC
AATCCTGTACAAGAACAGATGGCATTAGGGGCAAAACTTGGTGTGCGAGGTACGCCCGCTATCTTTACTGAAGCAGGACA
GCAAGTAGGCGGCTATCTACCTGCAGCTCAATTGGCAGAAGCAGTTGGCGCTAACTAA

Upstream 100 bases:

>100_bases
ATCGATCTAGTCATCATGTTAGATCAAAATTCCAAAAGATCTTCATTACCTTTTGCTATCAAAATCTTGATTAGGCATGA
CTGCCTAAAGGAAACATCCT

Downstream 100 bases:

>100_bases
AGACGGTTATATGCTTTAAGTATTTGTGATATGTATGACGGTGGCGACATTGTGTAGACGTCACAACTGCTTATCGGTAT
GATAGGATAAAGCGCTAGGC

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MFLAPFSKTNPNRDTFSRSPLTRVMSAALLVIVAAGCSNNAADATNNTDLVNSSKAKTSTAAVSKDSDAKVVKSLQANLK
ASGIEETILSAVPTDMTGIYWVTAEGLPSFFTDKTGKHIIQGQIIAVGAEAPVDISAALLASTAQEALKAVDKKDMVIYP
AKGATKAVVYAFTDADCGYCRKLHEEMDDINTRGIEVRYLAWPRSQESVPKMEAIWCSQDRKAAMNQGKAGADVQAPSCA
NPVQEQMALGAKLGVRGTPAIFTEAGQQVGGYLPAAQLAEAVGAN

Sequences:

>Translated_285_residues
MFLAPFSKTNPNRDTFSRSPLTRVMSAALLVIVAAGCSNNAADATNNTDLVNSSKAKTSTAAVSKDSDAKVVKSLQANLK
ASGIEETILSAVPTDMTGIYWVTAEGLPSFFTDKTGKHIIQGQIIAVGAEAPVDISAALLASTAQEALKAVDKKDMVIYP
AKGATKAVVYAFTDADCGYCRKLHEEMDDINTRGIEVRYLAWPRSQESVPKMEAIWCSQDRKAAMNQGKAGADVQAPSCA
NPVQEQMALGAKLGVRGTPAIFTEAGQQVGGYLPAAQLAEAVGAN
>Mature_285_residues
MFLAPFSKTNPNRDTFSRSPLTRVMSAALLVIVAAGCSNNAADATNNTDLVNSSKAKTSTAAVSKDSDAKVVKSLQANLK
ASGIEETILSAVPTDMTGIYWVTAEGLPSFFTDKTGKHIIQGQIIAVGAEAPVDISAALLASTAQEALKAVDKKDMVIYP
AKGATKAVVYAFTDADCGYCRKLHEEMDDINTRGIEVRYLAWPRSQESVPKMEAIWCSQDRKAAMNQGKAGADVQAPSCA
NPVQEQMALGAKLGVRGTPAIFTEAGQQVGGYLPAAQLAEAVGAN

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=219, Percent_Identity=36.986301369863, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 29973; Mature: 29973

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLAPFSKTNPNRDTFSRSPLTRVMSAALLVIVAAGCSNNAADATNNTDLVNSSKAKTST
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
AAVSKDSDAKVVKSLQANLKASGIEETILSAVPTDMTGIYWVTAEGLPSFFTDKTGKHII
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCEEE
QGQIIAVGAEAPVDISAALLASTAQEALKAVDKKDMVIYPAKGATKAVVYAFTDADCGYC
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHH
RKLHEEMDDINTRGIEVRYLAWPRSQESVPKMEAIWCSQDRKAAMNQGKAGADVQAPSCA
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
NPVQEQMALGAKLGVRGTPAIFTEAGQQVGGYLPAAQLAEAVGAN
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MFLAPFSKTNPNRDTFSRSPLTRVMSAALLVIVAAGCSNNAADATNNTDLVNSSKAKTST
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
AAVSKDSDAKVVKSLQANLKASGIEETILSAVPTDMTGIYWVTAEGLPSFFTDKTGKHII
HHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCEEE
QGQIIAVGAEAPVDISAALLASTAQEALKAVDKKDMVIYPAKGATKAVVYAFTDADCGYC
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEECCCHHHH
RKLHEEMDDINTRGIEVRYLAWPRSQESVPKMEAIWCSQDRKAAMNQGKAGADVQAPSCA
HHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCHHHHHHHCCCCCCCCCCCCCC
NPVQEQMALGAKLGVRGTPAIFTEAGQQVGGYLPAAQLAEAVGAN
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]