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The map label for this gene is ompR [H]

Identifier: 93004966

GI number: 93004966

Start: 157555

End: 158319

Strand: Reverse

Name: ompR [H]

Synonym: Pcryo_0135

Alternate gene names: 93004966

Gene position: 158319-157555 (Counterclockwise)

Preceding gene: 93004968

Following gene: 93004965

Centisome position: 5.17

GC content: 47.97

Gene sequence:

>765_bases
ATGTCTGAAAATAACAGCCCCGATACCTTAACTCAGCGTATTCTAGTCGTTGATGACGATGCACGATTGCGCTCTTTGTT
ACAGCGCTTTCTAGAAGACGATGGTTTTGTTGTCCGTACTGCCCACGATGGCAGTCAAATGGATAAGCTGTTGCAGCGTG
AGCTTTTTTCATTAGTGGTACTTGATTTGATGCTACCAGGCGAAGACGGTATCAGTATTTGTAAGCGTCTGCGCGAAGAC
AATGGCGACATCCCTATTATTATGCTCACGGCTAAAGGTGGCGACGCTGATCGCATCGCAGGTCTAGAAGCGGGTGCGGA
TGACTATCTACCAAAGCCATTTAATCCAAAAGAGCTATTAGCACGTATCAAAGCAGTACTCCGTCGTCAAAATCGTGAGC
TACCAGGGGCACCAAGTCATCAGCTTGAAGTAGTAGAATTTGGTCCATGGACACTTGATTTATCGACACGTACGCTCAAA
CGCGACGGCAATGTTGTCACCTTAACGACGGGTGAATTCTCGGTACTAAAGGCATTGGTTCAGCATCCACGCGAGCCATT
GACCCGTGATAAGCTGATGAACCTTGCCCGTGGTCGTGAATGGGGCGCGATGGAGCGTTCAATTGACGTTCAAGTATCAC
GTCTGCGCCGCTTAATTGAAGACAATCCTTCACAAGCACGTTATATCCAGACTGTCTGGGGCGTAGGCTATGTATTCGTA
CCTGACGAAGCAGAAGTCGAAGCAGCTAAGAGCGAATCACTTTAA

Upstream 100 bases:

>100_bases
AAAGTGGTATTCACACTGTTTTTATTGAGAGTAAATATACTGACTGGTGCGTTTTAACAATAATTTTTGCTAATAATAAT
TTTTATAAGAGGATGCCTGT

Downstream 100 bases:

>100_bases
ATTTCTAAGTATTGCTTGTGTCCGTTGATATATCATACTATTAATGGGTAATCCTATTAATACAACGGGCGCAACATTGA
AATCCTCTATTATTCATCAA

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MSENNSPDTLTQRILVVDDDARLRSLLQRFLEDDGFVVRTAHDGSQMDKLLQRELFSLVVLDLMLPGEDGISICKRLRED
NGDIPIIMLTAKGGDADRIAGLEAGADDYLPKPFNPKELLARIKAVLRRQNRELPGAPSHQLEVVEFGPWTLDLSTRTLK
RDGNVVTLTTGEFSVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPSQARYIQTVWGVGYVFV
PDEAEVEAAKSESL

Sequences:

>Translated_254_residues
MSENNSPDTLTQRILVVDDDARLRSLLQRFLEDDGFVVRTAHDGSQMDKLLQRELFSLVVLDLMLPGEDGISICKRLRED
NGDIPIIMLTAKGGDADRIAGLEAGADDYLPKPFNPKELLARIKAVLRRQNRELPGAPSHQLEVVEFGPWTLDLSTRTLK
RDGNVVTLTTGEFSVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPSQARYIQTVWGVGYVFV
PDEAEVEAAKSESL
>Mature_253_residues
SENNSPDTLTQRILVVDDDARLRSLLQRFLEDDGFVVRTAHDGSQMDKLLQRELFSLVVLDLMLPGEDGISICKRLREDN
GDIPIIMLTAKGGDADRIAGLEAGADDYLPKPFNPKELLARIKAVLRRQNRELPGAPSHQLEVVEFGPWTLDLSTRTLKR
DGNVVTLTTGEFSVLKALVQHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPSQARYIQTVWGVGYVFVP
DEAEVEAAKSESL

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=67.8260869565217, Blast_Score=332, Evalue=1e-92,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=38.3620689655172, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=39.7435897435897, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=34.1880341880342, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=34.5833333333333, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=38.0952380952381, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=35.2422907488987, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=32.3275862068966, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=33.6134453781513, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=33.6244541484716, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=34.6320346320346, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.0396475770925, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790860, Length=227, Percent_Identity=29.0748898678414, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=30.0813008130081, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790437, Length=139, Percent_Identity=31.6546762589928, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=30.8333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=181, Percent_Identity=28.1767955801105, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=32.3529411764706, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28556; Mature: 28425

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENNSPDTLTQRILVVDDDARLRSLLQRFLEDDGFVVRTAHDGSQMDKLLQRELFSLVV
CCCCCCCHHHHEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LDLMLPGEDGISICKRLREDNGDIPIIMLTAKGGDADRIAGLEAGADDYLPKPFNPKELL
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCHHHHH
ARIKAVLRRQNRELPGAPSHQLEVVEFGPWTLDLSTRTLKRDGNVVTLTTGEFSVLKALV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCHHHHHCCCCEEEEECCCHHHHHHHH
QHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPSQARYIQTVWGVGYVFV
HCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEE
PDEAEVEAAKSESL
CCCCHHHHHHCCCC
>Mature Secondary Structure 
SENNSPDTLTQRILVVDDDARLRSLLQRFLEDDGFVVRTAHDGSQMDKLLQRELFSLVV
CCCCCCHHHHEEEEEEECCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHH
LDLMLPGEDGISICKRLREDNGDIPIIMLTAKGGDADRIAGLEAGADDYLPKPFNPKELL
HHHHCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCHHHHH
ARIKAVLRRQNRELPGAPSHQLEVVEFGPWTLDLSTRTLKRDGNVVTLTTGEFSVLKALV
HHHHHHHHHHCCCCCCCCCCCEEEEEECCEEEECCHHHHHCCCCEEEEECCCHHHHHHHH
QHPREPLTRDKLMNLARGREWGAMERSIDVQVSRLRRLIEDNPSQARYIQTVWGVGYVFV
HCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEE
PDEAEVEAAKSESL
CCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]