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The map label for this gene is prlC [H]

Identifier: 93004915

GI number: 93004915

Start: 95335

End: 97530

Strand: Reverse

Name: prlC [H]

Synonym: Pcryo_0084

Alternate gene names: 93004915

Gene position: 97530-95335 (Counterclockwise)

Preceding gene: 93004919

Following gene: 93004914

Centisome position: 3.19

GC content: 44.31

Gene sequence:

>2196_bases
ATGACTTCTATTTCTTTAAAGTTACATCTTGTCGATTTTGCCGATACTGCACCAAGCACTTTACAACAGCAAGTAATCAG
CGCCATTGACACGGCTAATGCGTTTTTAGATGAGTTGACGGTGTGTACAGATAGCAAGGATACGTCTACCTCGATAGACG
CTGAGCAAGCGCTAAGTGATATAAAAAACTTTGACCACATCAATTTGGCATTGGATCGAAGTTGGGGCATTTTGTCGCAT
CTGAATAGTGTCATGAGTAATGATGAGATCCGCCATGTCCATCATGAGCTGTTACCAAAGCTATCAGCTTACGGTACGCG
CGTTGGGCAGCATCAGCCGCTATTTAGTCGTTATCAAGCGATTGTCAATGATAAAGCTTTCTTCGCAGCGCTTGAGCCGG
CACGAGCACGAGCTATTGAGCTTGCGCTACGTAGCTTTGAGTTATCAGGGGTCGCATTACCAAAAGCTGAGCAAGATAAA
TTTGCAGTCACTCAAAGTAAGCTGCCTACGTTATCAGCCACTTTCTCAGACCATGTTTTAGACGCCACTCAAGCTTATGC
GTTGCCGCTTAAAACAGAGCAGTTAGCAGGTTTGACTGAAAGTGGTTTGGCGCTATTGGCCGATGCAGGTGAGCAATATA
AAACAAGCCAGCTTGCAAATGGTTCGCTCACGCAAACAGAGGTTGATACCTTACCGATGCCTTATTATGTGGCAAGCTTA
AATATTCCTGTGTATCTTGCCATTATGACCCATGCCGATGATCGCAACTTACGCGAGACGTTATATCGTGCCTATGTCAC
TCGCGCCTCTGAGTTTGATGATCATACTAATGCTAAAGGTCAGTCTCTAAATAACGCAAATATCATGAGTGAGATTTTGC
AGTTACGTGAACAAAAAGCCAGACTATTGGGTTTTGATAACTATGCAGAGGTATCGCTATCGACCAAAATGGCAGACAGC
GTGGCAGAAGTAGAAACCTTTTTACGTGATTTAGCAGTGCAAGCAACGCCAACTGCTGCGCAAGATTTGGCGCAATTGCA
AAAATATGCGCAAGATTACGGTATTGAAGATTTGCAGCCGTGGGACAGTGCTTATATCGCCGAAAAGGTCAAACAAAGCG
AGTTCAGCTTATCACAAGAAGAGATTCGCCCGTATTTCCCATTACCAAAAGTGATTAGCGGTTTATTCGCTATCGTTGAG
CGTTTATACGGTATCAAAGTACAAGAGCAAAATGAATCCGTATTACGCTGGCATGATGAGGTGCGTTTTTATCAGTTATT
TGATGCTGATGATAACTTGCTTGGCGGTTTTTACTTTGATTTATTTGCCCGTAGTGGTAAACGCGGCGGCGCCTGGATGA
GTGGCTTTCAGTCACGTTATAGTTATGAAGAGCAAAACCACCAACAGTTACCAGTGTGCTTTATGGTCGGTAACTTCACC
CCAGCACTCGATGGTAAGCCAAGCTTATTGACTCATGATGAAGTTGTCACCTTGTTTCATGAGTTTGGTCATGGTCTTCA
TCATTTATTAACCCAAGTGACGGTCGGTGATGTCGCTGGGGTCAATGGCGTAGAATGGGATGCCGTCGAGCTGCCGAGTC
AGTTTATGGAAAACTGGGCGTGGGACGCGGAAGGTATTGCTCTTATTAGCAGTCATGTCGAAACTGGCACGCCATTACCA
AAAGAGAAACTCGATGCACTATTGGCAGTCAAAAACTTCCAAAGTGGTTTGCAAACGCTCCGTCAGATCGAATTTGCTTT
GTTTGATTTGTTGATCCATGCGCACACGCCGGCGCTCGATTATGAAGGTATTTTGACTACGCTTAACAGCGTACGTAATG
ATATTGCCATTTTACAGACGCCTGATTACAACCGCTTTGCCAATGGCTTTAGTCACATTTTTGCTGGTGGTTATGCCGCT
GGTTATTATTCTTATAAATGGGCAGAGCTGTTGTCTGCTGATGCTTTTAGTAAATTTGAAGAAGACGGCATTTTTAATCC
CATCACAGGTAAAGCCTTCCGTGAGACTATTTTATCAGTGGGCGGTAGTTTTCCAGCTAAGGTGAATTTCGAAAACTTCC
GTGGTCGTAGCGCCAGTATTGATGCTTTGCTACGTCATAGCGGTTTTTCTGATACTAAAGACCAGACTAAAAGTAGTACG
GCTGCCAATGCCTCAATAACACGCGAGGTGATTTAA

Upstream 100 bases:

>100_bases
TATAAACAGTAATGCCTGTTAATCATTTGAACGATTTGAATAATTACGCCAAATTAAACCCTTTTATCTGTCAAACTCAT
TATTTATAACGGAACCTTTT

Downstream 100 bases:

>100_bases
ATGCGCTATCAATCAACGCGTCCAAAGCGGCAGTTTTTAGCGGGCGTTCGCTGCCCGAAATGTCAGGTCATGGATGCGGT
AGTACAAGTCAATATCGTTG

Product: oligopeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MTSISLKLHLVDFADTAPSTLQQQVISAIDTANAFLDELTVCTDSKDTSTSIDAEQALSDIKNFDHINLALDRSWGILSH
LNSVMSNDEIRHVHHELLPKLSAYGTRVGQHQPLFSRYQAIVNDKAFFAALEPARARAIELALRSFELSGVALPKAEQDK
FAVTQSKLPTLSATFSDHVLDATQAYALPLKTEQLAGLTESGLALLADAGEQYKTSQLANGSLTQTEVDTLPMPYYVASL
NIPVYLAIMTHADDRNLRETLYRAYVTRASEFDDHTNAKGQSLNNANIMSEILQLREQKARLLGFDNYAEVSLSTKMADS
VAEVETFLRDLAVQATPTAAQDLAQLQKYAQDYGIEDLQPWDSAYIAEKVKQSEFSLSQEEIRPYFPLPKVISGLFAIVE
RLYGIKVQEQNESVLRWHDEVRFYQLFDADDNLLGGFYFDLFARSGKRGGAWMSGFQSRYSYEEQNHQQLPVCFMVGNFT
PALDGKPSLLTHDEVVTLFHEFGHGLHHLLTQVTVGDVAGVNGVEWDAVELPSQFMENWAWDAEGIALISSHVETGTPLP
KEKLDALLAVKNFQSGLQTLRQIEFALFDLLIHAHTPALDYEGILTTLNSVRNDIAILQTPDYNRFANGFSHIFAGGYAA
GYYSYKWAELLSADAFSKFEEDGIFNPITGKAFRETILSVGGSFPAKVNFENFRGRSASIDALLRHSGFSDTKDQTKSST
AANASITREVI

Sequences:

>Translated_731_residues
MTSISLKLHLVDFADTAPSTLQQQVISAIDTANAFLDELTVCTDSKDTSTSIDAEQALSDIKNFDHINLALDRSWGILSH
LNSVMSNDEIRHVHHELLPKLSAYGTRVGQHQPLFSRYQAIVNDKAFFAALEPARARAIELALRSFELSGVALPKAEQDK
FAVTQSKLPTLSATFSDHVLDATQAYALPLKTEQLAGLTESGLALLADAGEQYKTSQLANGSLTQTEVDTLPMPYYVASL
NIPVYLAIMTHADDRNLRETLYRAYVTRASEFDDHTNAKGQSLNNANIMSEILQLREQKARLLGFDNYAEVSLSTKMADS
VAEVETFLRDLAVQATPTAAQDLAQLQKYAQDYGIEDLQPWDSAYIAEKVKQSEFSLSQEEIRPYFPLPKVISGLFAIVE
RLYGIKVQEQNESVLRWHDEVRFYQLFDADDNLLGGFYFDLFARSGKRGGAWMSGFQSRYSYEEQNHQQLPVCFMVGNFT
PALDGKPSLLTHDEVVTLFHEFGHGLHHLLTQVTVGDVAGVNGVEWDAVELPSQFMENWAWDAEGIALISSHVETGTPLP
KEKLDALLAVKNFQSGLQTLRQIEFALFDLLIHAHTPALDYEGILTTLNSVRNDIAILQTPDYNRFANGFSHIFAGGYAA
GYYSYKWAELLSADAFSKFEEDGIFNPITGKAFRETILSVGGSFPAKVNFENFRGRSASIDALLRHSGFSDTKDQTKSST
AANASITREVI
>Mature_730_residues
TSISLKLHLVDFADTAPSTLQQQVISAIDTANAFLDELTVCTDSKDTSTSIDAEQALSDIKNFDHINLALDRSWGILSHL
NSVMSNDEIRHVHHELLPKLSAYGTRVGQHQPLFSRYQAIVNDKAFFAALEPARARAIELALRSFELSGVALPKAEQDKF
AVTQSKLPTLSATFSDHVLDATQAYALPLKTEQLAGLTESGLALLADAGEQYKTSQLANGSLTQTEVDTLPMPYYVASLN
IPVYLAIMTHADDRNLRETLYRAYVTRASEFDDHTNAKGQSLNNANIMSEILQLREQKARLLGFDNYAEVSLSTKMADSV
AEVETFLRDLAVQATPTAAQDLAQLQKYAQDYGIEDLQPWDSAYIAEKVKQSEFSLSQEEIRPYFPLPKVISGLFAIVER
LYGIKVQEQNESVLRWHDEVRFYQLFDADDNLLGGFYFDLFARSGKRGGAWMSGFQSRYSYEEQNHQQLPVCFMVGNFTP
ALDGKPSLLTHDEVVTLFHEFGHGLHHLLTQVTVGDVAGVNGVEWDAVELPSQFMENWAWDAEGIALISSHVETGTPLPK
EKLDALLAVKNFQSGLQTLRQIEFALFDLLIHAHTPALDYEGILTTLNSVRNDIAILQTPDYNRFANGFSHIFAGGYAAG
YYSYKWAELLSADAFSKFEEDGIFNPITGKAFRETILSVGGSFPAKVNFENFRGRSASIDALLRHSGFSDTKDQTKSSTA
ANASITREVI

Specific function: May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. Can cleave N-acetyl-L-Ala(4) [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=666, Percent_Identity=30.4804804804805, Blast_Score=284, Evalue=3e-76,
Organism=Homo sapiens, GI14149738, Length=666, Percent_Identity=28.6786786786787, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI156105687, Length=652, Percent_Identity=22.239263803681, Blast_Score=147, Evalue=4e-35,
Organism=Escherichia coli, GI1789913, Length=691, Percent_Identity=44.2836468885673, Blast_Score=583, Evalue=1e-167,
Organism=Escherichia coli, GI1787819, Length=666, Percent_Identity=30.3303303303303, Blast_Score=256, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71999758, Length=470, Percent_Identity=25.1063829787234, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI32565901, Length=432, Percent_Identity=24.3055555555556, Blast_Score=88, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319793, Length=656, Percent_Identity=30.4878048780488, Blast_Score=276, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6322715, Length=710, Percent_Identity=23.5211267605634, Blast_Score=139, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21356111, Length=490, Percent_Identity=32.8571428571429, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI20129717, Length=498, Percent_Identity=25.9036144578313, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.24.70 [H]

Molecular weight: Translated: 81181; Mature: 81050

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSISLKLHLVDFADTAPSTLQQQVISAIDTANAFLDELTVCTDSKDTSTSIDAEQALSD
CCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
IKNFDHINLALDRSWGILSHLNSVMSNDEIRHVHHELLPKLSAYGTRVGQHQPLFSRYQA
HCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IVNDKAFFAALEPARARAIELALRSFELSGVALPKAEQDKFAVTQSKLPTLSATFSDHVL
HHCCCHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHCCCCCCCCHHHHHH
DATQAYALPLKTEQLAGLTESGLALLADAGEQYKTSQLANGSLTQTEVDTLPMPYYVASL
HHHHHHCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCHHCCCCCCEEEEEE
NIPVYLAIMTHADDRNLRETLYRAYVTRASEFDDHTNAKGQSLNNANIMSEILQLREQKA
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RLLGFDNYAEVSLSTKMADSVAEVETFLRDLAVQATPTAAQDLAQLQKYAQDYGIEDLQP
HHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
WDSAYIAEKVKQSEFSLSQEEIRPYFPLPKVISGLFAIVERLYGIKVQEQNESVLRWHDE
CHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHH
VRFYQLFDADDNLLGGFYFDLFARSGKRGGAWMSGFQSRYSYEEQNHQQLPVCFMVGNFT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
PALDGKPSLLTHDEVVTLFHEFGHGLHHLLTQVTVGDVAGVNGVEWDAVELPSQFMENWA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
WDAEGIALISSHVETGTPLPKEKLDALLAVKNFQSGLQTLRQIEFALFDLLIHAHTPALD
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YEGILTTLNSVRNDIAILQTPDYNRFANGFSHIFAGGYAAGYYSYKWAELLSADAFSKFE
HHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
EDGIFNPITGKAFRETILSVGGSFPAKVNFENFRGRSASIDALLRHSGFSDTKDQTKSST
HCCCCCCCCCHHHHHHHHHHCCCCCCEECHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCH
AANASITREVI
HCCCCHHHHCC
>Mature Secondary Structure 
TSISLKLHLVDFADTAPSTLQQQVISAIDTANAFLDELTVCTDSKDTSTSIDAEQALSD
CCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
IKNFDHINLALDRSWGILSHLNSVMSNDEIRHVHHELLPKLSAYGTRVGQHQPLFSRYQA
HCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
IVNDKAFFAALEPARARAIELALRSFELSGVALPKAEQDKFAVTQSKLPTLSATFSDHVL
HHCCCHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCHHHHHHCCCCCCCCHHHHHH
DATQAYALPLKTEQLAGLTESGLALLADAGEQYKTSQLANGSLTQTEVDTLPMPYYVASL
HHHHHHCCCCCHHHHCCCCCCCCEEECCCCCHHHHHHHCCCCCCCCHHCCCCCCEEEEEE
NIPVYLAIMTHADDRNLRETLYRAYVTRASEFDDHTNAKGQSLNNANIMSEILQLREQKA
CCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
RLLGFDNYAEVSLSTKMADSVAEVETFLRDLAVQATPTAAQDLAQLQKYAQDYGIEDLQP
HHCCCCCCHHEEEHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCC
WDSAYIAEKVKQSEFSLSQEEIRPYFPLPKVISGLFAIVERLYGIKVQEQNESVLRWHDE
CHHHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHH
VRFYQLFDADDNLLGGFYFDLFARSGKRGGAWMSGFQSRYSYEEQNHQQLPVCFMVGNFT
CEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCC
PALDGKPSLLTHDEVVTLFHEFGHGLHHLLTQVTVGDVAGVNGVEWDAVELPSQFMENWA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCC
WDAEGIALISSHVETGTPLPKEKLDALLAVKNFQSGLQTLRQIEFALFDLLIHAHTPALD
CCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
YEGILTTLNSVRNDIAILQTPDYNRFANGFSHIFAGGYAAGYYSYKWAELLSADAFSKFE
HHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
EDGIFNPITGKAFRETILSVGGSFPAKVNFENFRGRSASIDALLRHSGFSDTKDQTKSST
HCCCCCCCCCHHHHHHHHHHCCCCCCEECHHHCCCCCHHHHHHHHHCCCCCCHHHHHCCH
AANASITREVI
HCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]