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The map label for this gene is xerD [H]

Identifier: 93004888

GI number: 93004888

Start: 66607

End: 67545

Strand: Reverse

Name: xerD [H]

Synonym: Pcryo_0057

Alternate gene names: 93004888

Gene position: 67545-66607 (Counterclockwise)

Preceding gene: 93004889

Following gene: 93004886

Centisome position: 2.21

GC content: 48.46

Gene sequence:

>939_bases
ATGAGCCGCGACCGTGCCGTACAGCAGCGCCAACCAAAAGCGCTGGCCGTAGATGATGAACCGGCTTATATAACCGAATT
TCGTCAAGCAATGCTGGCTCGTGGTTTGGCCACGCGTACCCGTAACGCCTATGTGCGTGATTTGCGCTCCTGCGAATTGA
CCAATCATACGGCATTAACGCGTTGGCAGCCCGAAGATGTGCTGCACTGCCTGTCTATTCTTACTCAAGATGGCAAAACG
CCGCGTACGCAAGCGCGCATGCTTTCAAGTTTGCGTCAGTTTTATCTGTGGATGATTGCCAGCAACCTACGTGAAGACAA
TCCTTGTGAGCGTATTAAAAGCCCAAAACTTGGTCGTCCACTGCCAAAAGATTTGGCAGAAGCTGACGTCGACAATCTCC
TTGCCGCGCCCGATAGCAGTACTGCGCTAGGGCTACGTGATAAAGCCATGTTAGAGGTACTTTACGCTTGCGGTTTGCGC
GTTAGTGAGTTGGTTAACTTGTCTCTTGAACAAGTGAATCTAAACTCAGGCTGGCTACAAATCACGGGGAAAGGCAATAA
AACCCGCTTAGTGCCTTTAGGGGAATATGCAGCAGATGCGCTTGAAGATTATTTGACGCATGGACGTGGTGATTTGATAG
CCCATTTAAAAGCAGGAAATTGCCAAGCAGTTTTTTTGACCGCCCAAGGCGGCTATATGACCCGGCAAAACTTTTGGTAT
CTACTAAAGAAATACGCCAAAGTTGCCAGTATTGATAAAGACCTATCACCGCATACCTTACGCCATGCTTTTGCTACCCA
TTTACTCAATCACGGTGCCGATTTACGGAGTGTGCAGTTATTGCTTGGACATAGTGATTTATCGACGACGCAGATATATA
CCCATGTGGCGACGGCTAGATTGCAAAAACTTCATGCTGAACACCATCCACGGGGTTAG

Upstream 100 bases:

>100_bases
AATGACTTTGCCAAATTTTATTAACTGATAGTCAACTTAAATATAAAAAATATCATTTATATCCACTTGTAATTTCTTAT
ACCACTGCCGAGTATGTTTT

Downstream 100 bases:

>100_bases
ATTACTGATGTACAAGATATTATTACCAATATAAAAAATTATAAATCGAAGTAAAAAAACGGCAATATTATAATGATACT
GCCGTTTTTTCATACTTAAT

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSRDRAVQQRQPKALAVDDEPAYITEFRQAMLARGLATRTRNAYVRDLRSCELTNHTALTRWQPEDVLHCLSILTQDGKT
PRTQARMLSSLRQFYLWMIASNLREDNPCERIKSPKLGRPLPKDLAEADVDNLLAAPDSSTALGLRDKAMLEVLYACGLR
VSELVNLSLEQVNLNSGWLQITGKGNKTRLVPLGEYAADALEDYLTHGRGDLIAHLKAGNCQAVFLTAQGGYMTRQNFWY
LLKKYAKVASIDKDLSPHTLRHAFATHLLNHGADLRSVQLLLGHSDLSTTQIYTHVATARLQKLHAEHHPRG

Sequences:

>Translated_312_residues
MSRDRAVQQRQPKALAVDDEPAYITEFRQAMLARGLATRTRNAYVRDLRSCELTNHTALTRWQPEDVLHCLSILTQDGKT
PRTQARMLSSLRQFYLWMIASNLREDNPCERIKSPKLGRPLPKDLAEADVDNLLAAPDSSTALGLRDKAMLEVLYACGLR
VSELVNLSLEQVNLNSGWLQITGKGNKTRLVPLGEYAADALEDYLTHGRGDLIAHLKAGNCQAVFLTAQGGYMTRQNFWY
LLKKYAKVASIDKDLSPHTLRHAFATHLLNHGADLRSVQLLLGHSDLSTTQIYTHVATARLQKLHAEHHPRG
>Mature_311_residues
SRDRAVQQRQPKALAVDDEPAYITEFRQAMLARGLATRTRNAYVRDLRSCELTNHTALTRWQPEDVLHCLSILTQDGKTP
RTQARMLSSLRQFYLWMIASNLREDNPCERIKSPKLGRPLPKDLAEADVDNLLAAPDSSTALGLRDKAMLEVLYACGLRV
SELVNLSLEQVNLNSGWLQITGKGNKTRLVPLGEYAADALEDYLTHGRGDLIAHLKAGNCQAVFLTAQGGYMTRQNFWYL
LKKYAKVASIDKDLSPHTLRHAFATHLLNHGADLRSVQLLLGHSDLSTTQIYTHVATARLQKLHAEHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=296, Percent_Identity=52.3648648648649, Blast_Score=274, Evalue=6e-75,
Organism=Escherichia coli, GI1790244, Length=289, Percent_Identity=34.9480968858132, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1790768, Length=164, Percent_Identity=31.0975609756098, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35010; Mature: 34878

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRDRAVQQRQPKALAVDDEPAYITEFRQAMLARGLATRTRNAYVRDLRSCELTNHTALT
CCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
RWQPEDVLHCLSILTQDGKTPRTQARMLSSLRQFYLWMIASNLREDNPCERIKSPKLGRP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCC
LPKDLAEADVDNLLAAPDSSTALGLRDKAMLEVLYACGLRVSELVNLSLEQVNLNSGWLQ
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCHHHEEECCCCEEE
ITGKGNKTRLVPLGEYAADALEDYLTHGRGDLIAHLKAGNCQAVFLTAQGGYMTRQNFWY
EEECCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHH
LLKKYAKVASIDKDLSPHTLRHAFATHLLNHGADLRSVQLLLGHSDLSTTQIYTHVATAR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LQKLHAEHHPRG
HHHHHHHCCCCC
>Mature Secondary Structure 
SRDRAVQQRQPKALAVDDEPAYITEFRQAMLARGLATRTRNAYVRDLRSCELTNHTALT
CCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEC
RWQPEDVLHCLSILTQDGKTPRTQARMLSSLRQFYLWMIASNLREDNPCERIKSPKLGRP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCC
LPKDLAEADVDNLLAAPDSSTALGLRDKAMLEVLYACGLRVSELVNLSLEQVNLNSGWLQ
CCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHCCHHHEEECCCCEEE
ITGKGNKTRLVPLGEYAADALEDYLTHGRGDLIAHLKAGNCQAVFLTAQGGYMTRQNFWY
EEECCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHH
LLKKYAKVASIDKDLSPHTLRHAFATHLLNHGADLRSVQLLLGHSDLSTTQIYTHVATAR
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHH
LQKLHAEHHPRG
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12534463 [H]