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The map label for this gene is rspB [H]

Identifier: 92115091

GI number: 92115091

Start: 3313207

End: 3314229

Strand: Direct

Name: rspB [H]

Synonym: Csal_2975

Alternate gene names: 92115091

Gene position: 3313207-3314229 (Clockwise)

Preceding gene: 92115090

Following gene: 92115092

Centisome position: 89.63

GC content: 68.82

Gene sequence:

>1023_bases
ATGAAAGCATTCGAGGTTCGCGCCCCCCACGACTTCGGCATCGTCGACATCGATGCCCCGCAGGCCGCCGCCGGCGAGGT
GCTGGTCGGCGTCGCCTTCGCCGGGATCTGTGGCTCGGACATGCACATCATCCACGGCGAGAACGCCTTCGTGCGGTTCC
CACGCATCACCGGCCACGAGTTCGCCGGCATCGTCGAGGACATCGGCGACGGCGTCGAGGGCCTCGCGGTGTGCGACCGG
GTGTGCATCGACCCGGTCATCAGCTGCGGCGAGTGCTACCCGTGCCGCATCGGCCGTCCCAATGTCTGTACCCGGCTCGC
CGTGATCGGCGTGCACCGCAACGGCGGCTTCGAGCAGCGCGTCAGCGTGCCGGCGGACAACGTGCACCGCCTGCCGGCGA
ACGTCGGTCTCGACCAGGCCGCGCTGGTCGAACCGTACACCATCGCGGCCAATGTGCTGGAGCGCATGCAGCCGCATGAC
GGCGACGCCCTGCTGATCCTCGGCGCCGGCGTGATCGGCCTGACCATCCTGCAGGTCGCCCGCGCCAAGGGGCTCACCGA
CATCACCGTCTGCGACGTCATCGACGACCGCCTGGATGCCGCCCGCTCGCTGGGCGCCAGCCACACCGTCAATGGACAAC
GACAGGACCTGGAGGCCGTGATGAGCGAGCGCAGCGACGGCGAGGGCATTCCGCTGATCGCCGACGCCGCCTGCGTGCCG
GCCCTGTTCCCGCAGCTGGCGCGCATCGCCTCACCGGCCGGGCGCATCGGGCTGCTGGGTTTCAACGCCACGCCCAGCGA
CCTGGTTCAGCTCGAGGTGATCAAGAAGGAGCTGACGATCGTCGGCTCGCGCCTCAACAACCGCAAGTTTCCCGACGTCA
TCGAGATGCTCGCCAGCGGGCGGCTCGATGCCTCGGCGCTGGTCAGCCACCGGCTGCCCTTCGCCGAGATGGGTGAGGCG
ATCCACATGATCGACCATCACCCGGAACGGGTGCGCAAGGTGCTCATCGAGCTCGGTGCCTGA

Upstream 100 bases:

>100_bases
GTATCCCTACGAACGCGCCAGCCTGCCGGTCAACCGTCTGGAAGACGGCACGCTCTGGCACTGGTGATCCCGTCTTCCCT
TATCCAGAGCGGAGTCCGTC

Downstream 100 bases:

>100_bases
CGCATCGCGCGATGCGCCTCGCGCTCCACAACGCTGGATTGCCGGACACTTCAATGCTCGACAACAACAGCCATCAATCG
AAGTCAGGAGCAACGTCATG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKAFEVRAPHDFGIVDIDAPQAAAGEVLVGVAFAGICGSDMHIIHGENAFVRFPRITGHEFAGIVEDIGDGVEGLAVCDR
VCIDPVISCGECYPCRIGRPNVCTRLAVIGVHRNGGFEQRVSVPADNVHRLPANVGLDQAALVEPYTIAANVLERMQPHD
GDALLILGAGVIGLTILQVARAKGLTDITVCDVIDDRLDAARSLGASHTVNGQRQDLEAVMSERSDGEGIPLIADAACVP
ALFPQLARIASPAGRIGLLGFNATPSDLVQLEVIKKELTIVGSRLNNRKFPDVIEMLASGRLDASALVSHRLPFAEMGEA
IHMIDHHPERVRKVLIELGA

Sequences:

>Translated_340_residues
MKAFEVRAPHDFGIVDIDAPQAAAGEVLVGVAFAGICGSDMHIIHGENAFVRFPRITGHEFAGIVEDIGDGVEGLAVCDR
VCIDPVISCGECYPCRIGRPNVCTRLAVIGVHRNGGFEQRVSVPADNVHRLPANVGLDQAALVEPYTIAANVLERMQPHD
GDALLILGAGVIGLTILQVARAKGLTDITVCDVIDDRLDAARSLGASHTVNGQRQDLEAVMSERSDGEGIPLIADAACVP
ALFPQLARIASPAGRIGLLGFNATPSDLVQLEVIKKELTIVGSRLNNRKFPDVIEMLASGRLDASALVSHRLPFAEMGEA
IHMIDHHPERVRKVLIELGA
>Mature_340_residues
MKAFEVRAPHDFGIVDIDAPQAAAGEVLVGVAFAGICGSDMHIIHGENAFVRFPRITGHEFAGIVEDIGDGVEGLAVCDR
VCIDPVISCGECYPCRIGRPNVCTRLAVIGVHRNGGFEQRVSVPADNVHRLPANVGLDQAALVEPYTIAANVLERMQPHD
GDALLILGAGVIGLTILQVARAKGLTDITVCDVIDDRLDAARSLGASHTVNGQRQDLEAVMSERSDGEGIPLIADAACVP
ALFPQLARIASPAGRIGLLGFNATPSDLVQLEVIKKELTIVGSRLNNRKFPDVIEMLASGRLDASALVSHRLPFAEMGEA
IHMIDHHPERVRKVLIELGA

Specific function: Not known; probable catabolic enzyme [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=326, Percent_Identity=28.2208588957055, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI4501929, Length=367, Percent_Identity=24.2506811989101, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI34577061, Length=366, Percent_Identity=25.1366120218579, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=25, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI156523966, Length=348, Percent_Identity=24.4252873563218, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501939, Length=348, Percent_Identity=24.4252873563218, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=22.911051212938, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI71565152, Length=377, Percent_Identity=24.1379310344828, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1787863, Length=339, Percent_Identity=43.6578171091445, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1790045, Length=320, Percent_Identity=30.3125, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1788407, Length=308, Percent_Identity=29.8701298701299, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI226510992, Length=323, Percent_Identity=29.1021671826625, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788073, Length=332, Percent_Identity=30.1204819277108, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788075, Length=342, Percent_Identity=25.7309941520468, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790718, Length=305, Percent_Identity=25.9016393442623, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786825, Length=390, Percent_Identity=24.6153846153846, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082125, Length=326, Percent_Identity=24.8466257668712, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081918, Length=233, Percent_Identity=28.3261802575107, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786552, Length=356, Percent_Identity=24.7191011235955, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786518, Length=309, Percent_Identity=26.2135922330097, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082401, Length=130, Percent_Identity=32.3076923076923, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562876, Length=321, Percent_Identity=32.7102803738318, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17562878, Length=326, Percent_Identity=31.9018404907975, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25146526, Length=369, Percent_Identity=23.0352303523035, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997431, Length=369, Percent_Identity=22.4932249322493, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562584, Length=281, Percent_Identity=26.6903914590747, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71988145, Length=170, Percent_Identity=31.1764705882353, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323099, Length=346, Percent_Identity=27.4566473988439, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6322619, Length=322, Percent_Identity=25.776397515528, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319955, Length=322, Percent_Identity=25.4658385093168, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319257, Length=313, Percent_Identity=26.1980830670927, Blast_Score=106, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319258, Length=218, Percent_Identity=31.1926605504587, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=281, Percent_Identity=28.8256227758007, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6320033, Length=379, Percent_Identity=23.2189973614776, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=281, Percent_Identity=27.4021352313167, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=285, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=281, Percent_Identity=25.9786476868327, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17737897, Length=314, Percent_Identity=31.2101910828025, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI17137530, Length=310, Percent_Identity=31.6129032258064, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI221457811, Length=331, Percent_Identity=25.0755287009063, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI45551930, Length=331, Percent_Identity=25.0755287009063, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI45550770, Length=331, Percent_Identity=25.0755287009063, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI17737895, Length=375, Percent_Identity=21.6, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.- [C]

Molecular weight: Translated: 36175; Mature: 36175

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFEVRAPHDFGIVDIDAPQAAAGEVLVGVAFAGICGSDMHIIHGENAFVRFPRITGHE
CCCEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCHH
FAGIVEDIGDGVEGLAVCDRVCIDPVISCGECYPCRIGRPNVCTRLAVIGVHRNGGFEQR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCC
VSVPADNVHRLPANVGLDQAALVEPYTIAANVLERMQPHDGDALLILGAGVIGLTILQVA
CCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
RAKGLTDITVCDVIDDRLDAARSLGASHTVNGQRQDLEAVMSERSDGEGIPLIADAACVP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECHHHHH
ALFPQLARIASPAGRIGLLGFNATPSDLVQLEVIKKELTIVGSRLNNRKFPDVIEMLASG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
RLDASALVSHRLPFAEMGEAIHMIDHHPERVRKVLIELGA
CCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKAFEVRAPHDFGIVDIDAPQAAAGEVLVGVAFAGICGSDMHIIHGENAFVRFPRITGHE
CCCEECCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCHH
FAGIVEDIGDGVEGLAVCDRVCIDPVISCGECYPCRIGRPNVCTRLAVIGVHRNGGFEQR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHEEEEEEEECCCCCCCC
VSVPADNVHRLPANVGLDQAALVEPYTIAANVLERMQPHDGDALLILGAGVIGLTILQVA
CCCCCCHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHH
RAKGLTDITVCDVIDDRLDAARSLGASHTVNGQRQDLEAVMSERSDGEGIPLIADAACVP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCEEECHHHHH
ALFPQLARIASPAGRIGLLGFNATPSDLVQLEVIKKELTIVGSRLNNRKFPDVIEMLASG
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
RLDASALVSHRLPFAEMGEAIHMIDHHPERVRKVLIELGA
CCCHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7545940; 9097039; 9278503 [H]