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The map label for this gene is hisS

Identifier: 92114972

GI number: 92114972

Start: 3185712

End: 3186998

Strand: Direct

Name: hisS

Synonym: Csal_2855

Alternate gene names: 92114972

Gene position: 3185712-3186998 (Clockwise)

Preceding gene: 92114971

Following gene: 92114973

Centisome position: 86.18

GC content: 64.57

Gene sequence:

>1287_bases
TTGAGCAACAAGATCCAGGCCATCCGTGGCATGAACGATCTGCTACCGGAGCAGTCGCCTGTCTGGCAGTATTTCGAGCG
CCAGATCCAGCATCTCATGCAGCGCTATGGGTACAACGAGATTCGCACGCCGATTCTCGAGCAGACCGCCCTGTTCAAGC
GCTCGATCGGCGAAGTCACCGATATCGTCGAAAAAGAGATGTACACCTTCGAGGACCGCAACGGCGACAGCCTGACGCTG
CGGCCCGAGGGCACCGCCAGCTGCGTGCGCGCCGCACTGGAGAATGGCCTGCTGTACAACCAGACCCAGCGTCTGTGGTA
CCAGGGTCCCATGTTCCGCCATGAGCGTCCCCAGAAAGGCCGCTATCGGCAATTCCACCAGGTCGGCGTGGAAGCCTACG
GCATGCTGGGGCCGGACATCGATTTCGAAATGATCCTGCTCAGTGCGCGGCTGTGGGATGCCCTGGGCCTGATGCCGCAC
GTCCGCCTGGAACTCAATTCCCTGGGCTCCAGCGAGGCGCGGGCCGCCTATCGCGACGCCTTGGTCGCGTATTTCGAGGC
CCATGCCGAGGTGCTCGACGAGGACTCGCGGCGCCGCCTGACCAGCAATCCGCTGCGCATCCTCGACTCCAAGAACCCCG
ACATGGCAGAGATGCTCGAGGCCGCGCCGCGCCTCATGGATCATCTCGACGACGAGTCGCGGGCGCACTTCGAGCAATTG
ACCGCCATGCTCGACGCGGCCGGCATCGATTACGTCATCAACCCGCGCCTCGTGCGTGGGCTGGACTATTACAGCCGAAC
CGTGTTCGAGTGGACCACCCAGGCGCTGGGCAGTCAGGGCACGGTATGCGCCGGCGGACGTTACGATGGCCTGGTCGAGC
AGCTCGGCGGCAAGCCCACGCCCGGCGTCGGCTTCGCCATGGGAGTCGAGCGTTTGATCCTGCTGCTCGAGACCCTGGAC
CTCGTGCCCGAGGCCGCGCGCTCGCGTCCCGACGTCTATCTCACGGCCATGGGCGACACCGCCAGCCGTGAGGCGATGCT
GCTGGGCGAGCATCTGCGTGACGCCCTGCCCGAAATGCACTTGCAGGTCCATTGCGGGGGTGGCAGTTTCAAGAGCCAGA
TCAAGAAGGCCGACAAGAGCGGTGCACGTATCGCCTTGATGCTCGGTGACGACGAGATCGCCAGCGGCAGCGTCGGCATC
AAGTTCCTGCGCGAGGATCGCGAGCAGGAAAGCGTGGCTCGGGAGGCGCTGGCGGCCCGTCTCCAAGCGCTTCTCGCCGA
AGACTGA

Upstream 100 bases:

>100_bases
GCGACAAGGTCCGCGAAAAAGAAGCCCGCGAACGCGATACCATCGCGCGCGAGGCATGACGCGCGCCGCTCGCGCCCCGT
AACCGGTTCAGGAGTCAGCA

Downstream 100 bases:

>100_bases
GGACGCCCCGGGGCGTATCGCACGAACAGCCATTGAAGGAGACCGCCCGTGGCGGAGCTTAGCACCGAAGACGAACAGCT
TGAGACGCTCAAGCGCTGGT

Product: histidyl-tRNA synthetase

Products: NA

Alternate protein names: Histidine--tRNA ligase; HisRS

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSNKIQAIRGMNDLLPEQSPVWQYFERQIQHLMQRYGYNEIRTPILEQTALFKRSIGEVTDIVEKEMYTFEDRNGDSLTL
RPEGTASCVRAALENGLLYNQTQRLWYQGPMFRHERPQKGRYRQFHQVGVEAYGMLGPDIDFEMILLSARLWDALGLMPH
VRLELNSLGSSEARAAYRDALVAYFEAHAEVLDEDSRRRLTSNPLRILDSKNPDMAEMLEAAPRLMDHLDDESRAHFEQL
TAMLDAAGIDYVINPRLVRGLDYYSRTVFEWTTQALGSQGTVCAGGRYDGLVEQLGGKPTPGVGFAMGVERLILLLETLD
LVPEAARSRPDVYLTAMGDTASREAMLLGEHLRDALPEMHLQVHCGGGSFKSQIKKADKSGARIALMLGDDEIASGSVGI
KFLREDREQESVAREALAARLQALLAED

Sequences:

>Translated_428_residues
MSNKIQAIRGMNDLLPEQSPVWQYFERQIQHLMQRYGYNEIRTPILEQTALFKRSIGEVTDIVEKEMYTFEDRNGDSLTL
RPEGTASCVRAALENGLLYNQTQRLWYQGPMFRHERPQKGRYRQFHQVGVEAYGMLGPDIDFEMILLSARLWDALGLMPH
VRLELNSLGSSEARAAYRDALVAYFEAHAEVLDEDSRRRLTSNPLRILDSKNPDMAEMLEAAPRLMDHLDDESRAHFEQL
TAMLDAAGIDYVINPRLVRGLDYYSRTVFEWTTQALGSQGTVCAGGRYDGLVEQLGGKPTPGVGFAMGVERLILLLETLD
LVPEAARSRPDVYLTAMGDTASREAMLLGEHLRDALPEMHLQVHCGGGSFKSQIKKADKSGARIALMLGDDEIASGSVGI
KFLREDREQESVAREALAARLQALLAED
>Mature_427_residues
SNKIQAIRGMNDLLPEQSPVWQYFERQIQHLMQRYGYNEIRTPILEQTALFKRSIGEVTDIVEKEMYTFEDRNGDSLTLR
PEGTASCVRAALENGLLYNQTQRLWYQGPMFRHERPQKGRYRQFHQVGVEAYGMLGPDIDFEMILLSARLWDALGLMPHV
RLELNSLGSSEARAAYRDALVAYFEAHAEVLDEDSRRRLTSNPLRILDSKNPDMAEMLEAAPRLMDHLDDESRAHFEQLT
AMLDAAGIDYVINPRLVRGLDYYSRTVFEWTTQALGSQGTVCAGGRYDGLVEQLGGKPTPGVGFAMGVERLILLLETLDL
VPEAARSRPDVYLTAMGDTASREAMLLGEHLRDALPEMHLQVHCGGGSFKSQIKKADKSGARIALMLGDDEIASGSVGIK
FLREDREQESVAREALAARLQALLAED

Specific function: Unknown

COG id: COG0124

COG function: function code J; Histidyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15029520, Length=462, Percent_Identity=24.2424242424242, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI6996014, Length=468, Percent_Identity=24.7863247863248, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788861, Length=427, Percent_Identity=62.9976580796253, Blast_Score=558, Evalue=1e-160,
Organism=Caenorhabditis elegans, GI71993686, Length=479, Percent_Identity=24.4258872651357, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71993693, Length=479, Percent_Identity=24.4258872651357, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYH_CHRSD (Q1QTK7)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574900.1
- ProteinModelPortal:   Q1QTK7
- SMR:   Q1QTK7
- STRING:   Q1QTK7
- GeneID:   4028657
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2855
- NMPDR:   fig|290398.4.peg.2439
- eggNOG:   COG0124
- HOGENOM:   HBG616575
- OMA:   VFEWVTT
- BioCyc:   CSAL290398:CSAL_2855-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00127
- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR015807
- InterPro:   IPR004516
- Gene3D:   G3DSA:3.40.50.800
- PANTHER:   PTHR11476
- PIRSF:   PIRSF001549
- TIGRFAMs:   TIGR00442

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b; SSF52954 Anticodon_bd

EC number: =6.1.1.21

Molecular weight: Translated: 48122; Mature: 47991

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKIQAIRGMNDLLPEQSPVWQYFERQIQHLMQRYGYNEIRTPILEQTALFKRSIGEVT
CCCHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHH
DIVEKEMYTFEDRNGDSLTLRPEGTASCVRAALENGLLYNQTQRLWYQGPMFRHERPQKG
HHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCEECHHHHHHHCCCCCCCCCCCCC
RYRQFHQVGVEAYGMLGPDIDFEMILLSARLWDALGLMPHVRLELNSLGSSEARAAYRDA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEHHHCCCHHHHHHHHHH
LVAYFEAHAEVLDEDSRRRLTSNPLRILDSKNPDMAEMLEAAPRLMDHLDDESRAHFEQL
HHHHHHHHHHHHCCHHHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
TAMLDAAGIDYVINPRLVRGLDYYSRTVFEWTTQALGSQGTVCAGGRYDGLVEQLGGKPT
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCC
PGVGFAMGVERLILLLETLDLVPEAARSRPDVYLTAMGDTASREAMLLGEHLRDALPEMH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCE
LQVHCGGGSFKSQIKKADKSGARIALMLGDDEIASGSVGIKFLREDREQESVAREALAAR
EEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQALLAED
HHHHHCCC
>Mature Secondary Structure 
SNKIQAIRGMNDLLPEQSPVWQYFERQIQHLMQRYGYNEIRTPILEQTALFKRSIGEVT
CCHHHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHH
DIVEKEMYTFEDRNGDSLTLRPEGTASCVRAALENGLLYNQTQRLWYQGPMFRHERPQKG
HHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCEECHHHHHHHCCCCCCCCCCCCC
RYRQFHQVGVEAYGMLGPDIDFEMILLSARLWDALGLMPHVRLELNSLGSSEARAAYRDA
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHEEEHHHCCCHHHHHHHHHH
LVAYFEAHAEVLDEDSRRRLTSNPLRILDSKNPDMAEMLEAAPRLMDHLDDESRAHFEQL
HHHHHHHHHHHHCCHHHHHHCCCCHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
TAMLDAAGIDYVINPRLVRGLDYYSRTVFEWTTQALGSQGTVCAGGRYDGLVEQLGGKPT
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCC
PGVGFAMGVERLILLLETLDLVPEAARSRPDVYLTAMGDTASREAMLLGEHLRDALPEMH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCE
LQVHCGGGSFKSQIKKADKSGARIALMLGDDEIASGSVGIKFLREDREQESVAREALAAR
EEEEECCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQALLAED
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA