BacMap

Definition	Chromohalobacter salexigens DSM 3043 chromosome, complete genome.
Accession	NC_007963
Length	3,696,649

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The map label for this gene is yvaG [H]

Identifier: 92114926

GI number: 92114926

Start: 3139290

End: 3140084

Strand: Direct

Name: yvaG [H]

Synonym: Csal_2809

Alternate gene names: 92114926

Gene position: 3139290-3140084 (Clockwise)

Preceding gene: 92114919

Following gene: 92114927

Centisome position: 84.92

GC content: 66.16

Gene sequence:

>795_bases
ATGCAGATCGATCTCAGCGGCAAATCCGCCATCGTCACCGGCTCCACCGCCGGCATCGGTTTCGCCATCGCCCAGGGACT
GGCCAATGCCGGCGCCGAGGTCACCCTGACCGGACGTACCCAGGCACGCGTCGACAAAGCGCTGAGCGACCTGAAAGCCG
CGGTCTCCGGCGCCAGGGTTTCCGGCGTCGCCGCCGACCTGGGCACCGCCGAAGGCTGCCAGGCGCTGATATCCGCTCGC
CCGGACACCGACATCCTGATCAACAACGTGGGGATCTTCGGTCCGCAGGATTTCTTCGAGACCGATGACGCCACCTGGGA
ACAATTCTTCCAGGTCAACGTGATGAGCGGGGTGCGCCTGTCGCGTCACTATGCGCAGGGCATGAAGGCACGCGGCTGGG
GACGCATTCAGTTCCTGTCCAGCGAATCGGCCCTCAACATCCCCGCCGAAATGGTGCATTACGGCATGACCAAGTCCGCC
GTGCAGTCGATCTCGCGCGGCCTGGCCAAGGTGATGGCGGGCACCGGCGTGACCGTCAACGCGGTGCTGCCGGGGCCGAC
ACGCTCCGAGGGCGTGGTCGACATGATCGCCAAGATGGCCGAGCAGGAAGGCGTGTCCCAGGAGGCCATGGAGGAACGCT
TCGTCAAGGAAAACCGCCCCAGCTCGATCATCGGACGGCTTGCCACGCCCGAGGAAGTCGCCAACATGTGCGTCTATGCC
GCATCGCCGCAGGCCAGCGCCACCACGGGCGCGCCGCTGCGCGTGGAAGGCGGCATCGTCGACAGCATGGCGTGA

Upstream 100 bases:

>100_bases
CCTGCTCGCCCCGACCAACTCATTTGCGGACTCACGATCGCGCCGCAGCGGGCGCGACACTCGCGTTAGACGACGCTCAC
GCAAGACAAGGAGGCTCGAC

Downstream 100 bases:

>100_bases
TCGTGCGCGCATGGCCCGATGTACCGGGCCATGCCTGCCCCAGACTCCAGGTTGCGCACGGATTGTCTCGCAAGCCCATT
CCCGCATGGACGCCCCGCCG

Product: short-chain dehydrogenase/reductase SDR

Products: 2,3-Dihydroxybenzoate; H+; Nicotinamide adenine dinucleotide - reduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQIDLSGKSAIVTGSTAGIGFAIAQGLANAGAEVTLTGRTQARVDKALSDLKAAVSGARVSGVAADLGTAEGCQALISAR
PDTDILINNVGIFGPQDFFETDDATWEQFFQVNVMSGVRLSRHYAQGMKARGWGRIQFLSSESALNIPAEMVHYGMTKSA
VQSISRGLAKVMAGTGVTVNAVLPGPTRSEGVVDMIAKMAEQEGVSQEAMEERFVKENRPSSIIGRLATPEEVANMCVYA
ASPQASATTGAPLRVEGGIVDSMA

Sequences:

>Translated_264_residues
MQIDLSGKSAIVTGSTAGIGFAIAQGLANAGAEVTLTGRTQARVDKALSDLKAAVSGARVSGVAADLGTAEGCQALISAR
PDTDILINNVGIFGPQDFFETDDATWEQFFQVNVMSGVRLSRHYAQGMKARGWGRIQFLSSESALNIPAEMVHYGMTKSA
VQSISRGLAKVMAGTGVTVNAVLPGPTRSEGVVDMIAKMAEQEGVSQEAMEERFVKENRPSSIIGRLATPEEVANMCVYA
ASPQASATTGAPLRVEGGIVDSMA
>Mature_264_residues
MQIDLSGKSAIVTGSTAGIGFAIAQGLANAGAEVTLTGRTQARVDKALSDLKAAVSGARVSGVAADLGTAEGCQALISAR
PDTDILINNVGIFGPQDFFETDDATWEQFFQVNVMSGVRLSRHYAQGMKARGWGRIQFLSSESALNIPAEMVHYGMTKSA
VQSISRGLAKVMAGTGVTVNAVLPGPTRSEGVVDMIAKMAEQEGVSQEAMEERFVKENRPSSIIGRLATPEEVANMCVYA
ASPQASATTGAPLRVEGGIVDSMA

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.1187739463602, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI5031737, Length=259, Percent_Identity=28.957528957529, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=32.2916666666667, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7705925, Length=260, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.7566539923954, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI19923817, Length=264, Percent_Identity=28.030303030303, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=253, Percent_Identity=26.4822134387352, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI10190746, Length=217, Percent_Identity=31.7972350230415, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705855, Length=185, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI146231950, Length=205, Percent_Identity=31.7073170731707, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI66933014, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI225579078, Length=204, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=31.0344827586207, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787335, Length=260, Percent_Identity=30.3846153846154, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=28.8461538461538, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787905, Length=266, Percent_Identity=28.9473684210526, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=28.90625, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790717, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789208, Length=265, Percent_Identity=27.5471698113208, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=27.1317829457364, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082160, Length=267, Percent_Identity=26.2172284644195, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=30.9160305343511, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17560676, Length=261, Percent_Identity=26.8199233716475, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=30.9701492537313, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=30.5019305019305, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=30.7086614173228, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=30.8270676691729, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=31.4606741573034, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=268, Percent_Identity=31.3432835820896, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=30.0380228136882, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=29.9242424242424, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=27.7153558052434, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=36.4583333333333, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=254, Percent_Identity=31.1023622047244, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=29.4776119402985, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=26.9662921348315, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=28.5185185185185, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=267, Percent_Identity=28.8389513108614, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17565030, Length=256, Percent_Identity=32.421875, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=29.296875, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=32.48730964467, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=27.1317829457364, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=262, Percent_Identity=30.5343511450382, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=30.6513409961686, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=30.6201550387597, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24639444, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=29.0196078431373, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=25.7692307692308, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=28.8973384030418, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24641232, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.3.1.28 [C]

Molecular weight: Translated: 27513; Mature: 27513

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIDLSGKSAIVTGSTAGIGFAIAQGLANAGAEVTLTGRTQARVDKALSDLKAAVSGARV
CEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHH
SGVAADLGTAEGCQALISARPDTDILINNVGIFGPQDFFETDDATWEQFFQVNVMSGVRL
HHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHH
SRHYAQGMKARGWGRIQFLSSESALNIPAEMVHYGMTKSAVQSISRGLAKVMAGTGVTVN
HHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEE
AVLPGPTRSEGVVDMIAKMAEQEGVSQEAMEERFVKENRPSSIIGRLATPEEVANMCVYA
EEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHEEEE
ASPQASATTGAPLRVEGGIVDSMA
CCCCCCCCCCCCEEECCCCCCCCC
>Mature Secondary Structure
MQIDLSGKSAIVTGSTAGIGFAIAQGLANAGAEVTLTGRTQARVDKALSDLKAAVSGARV
CEEECCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCHH
SGVAADLGTAEGCQALISARPDTDILINNVGIFGPQDFFETDDATWEQFFQVNVMSGVRL
HHHHHHCCCHHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHCHHH
SRHYAQGMKARGWGRIQFLSSESALNIPAEMVHYGMTKSAVQSISRGLAKVMAGTGVTVN
HHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEE
AVLPGPTRSEGVVDMIAKMAEQEGVSQEAMEERFVKENRPSSIIGRLATPEEVANMCVYA
EEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHEEEE
ASPQASATTGAPLRVEGGIVDSMA
CCCCCCCCCCCCEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 5550 [C]

Specific activity: 66

Km value (mM): 0.26 {methyl-2,3-dehydro-3-hydroxybenzoate}} 0.2 {3-oxocyclohexane-1-carboxylic} 0.3 {2,3-dihydro-2,3-dihydroxybenzoate}} [C]

Substrates: 2,3-Dihydro-2,3-dihydroxybenzoate; Nicotinamide adenine dinucleotide [C]

Specific reaction: 2,3-Dihydro-2,3-dihydroxybenzoate + Nicotinamide adenine dinucleotide <==> 2,3-Dihydroxybenzoate + H+ + Nicotinamide adenine dinucleotide - reduced [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]