BacMap

Definition	Chromohalobacter salexigens DSM 3043 chromosome, complete genome.
Accession	NC_007963
Length	3,696,649

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The map label for this gene is fabG [H]

Identifier: 92114878

GI number: 92114878

Start: 3091861

End: 3092586

Strand: Direct

Name: fabG [H]

Synonym: Csal_2760

Alternate gene names: 92114878

Gene position: 3091861-3092586 (Clockwise)

Preceding gene: 92114877

Following gene: 92114879

Centisome position: 83.64

GC content: 65.7

Gene sequence:

>726_bases
ATGAACGACACCATTCTGGTCACCGGCGCCAACCGTGGCATCGGTCGCGCCACCGCGTTGCGTCTGGCGCGCGACGGTTT
CGATATCGTCGTCCACTACCGCTCGCGCGAGCAGGAAGCCGAGGCCGTGGCCGAGGACATTCGCGCCCTGGGGCGCGAAG
CACGCCTGCTGCGTTTCGACGTGGCCGAGCGAGGCGAGGCCCGCGCGTGCCTGGAAGCCGATATCGAGCGTCACGGCGCC
TATTACGGCGTGGTGTGCAATGCCGGGATCACCGCCGACAACCCTTTCCCCGCGCTCACCGAAGACGACTGGGACAGCGT
GGTGCATACCAACCTCGACGGTTTCTACAACGTGCTGCATCCGCTGGTCATGCCGATGATCCGCCGCCGCAAACCGGGAC
GCATCGTCACCATCGCCTCGATGTCGGGCGTGATCGGCAACCGGGGACAGGTCAACTACAGCGCCGCCAAGGCGGGGGTC
ATCGGTGCCACCAAGGCATTGGCCATCGAGCTCGCCAAGCGCCATATCACCGTCAACTGCGTCGCCCCGGGCTGGATCGA
TACCGACATGACGCATCACCTGCCCCAGGAAGAGGTACGCAAGCTGATTCCCATGCGACGCACCGGGCAGGCCGAGGACG
TCGCCGGCGTGGTGAGCTTTCTCTGCTCCAGCGACGCCGCCTACATGACGCGCCAGGTATTGCCGGTGAATGGCGGCATG
TGCTGA

Upstream 100 bases:

>100_bases
CCACGCCCGCGGGCGAACCGCTCGCCGAAGGCCAGTTGAGCATCTTCCAGCCGGATACCGCATCGCTTTCCCCGGCACCA
TCCACCAGCCGAGAGACATG

Downstream 100 bases:

>100_bases
AAAGGCGTGTCGCGTGCCACCATCAAGCTTGGCGCAACGGGGCCGATAATGGGGAGACCCTCGTGGTAATGGATACGACA
CAATGAAACGCTTGGTTCTG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MNDTILVTGANRGIGRATALRLARDGFDIVVHYRSREQEAEAVAEDIRALGREARLLRFDVAERGEARACLEADIERHGA
YYGVVCNAGITADNPFPALTEDDWDSVVHTNLDGFYNVLHPLVMPMIRRRKPGRIVTIASMSGVIGNRGQVNYSAAKAGV
IGATKALAIELAKRHITVNCVAPGWIDTDMTHHLPQEEVRKLIPMRRTGQAEDVAGVVSFLCSSDAAYMTRQVLPVNGGM
C

Sequences:

>Translated_241_residues
MNDTILVTGANRGIGRATALRLARDGFDIVVHYRSREQEAEAVAEDIRALGREARLLRFDVAERGEARACLEADIERHGA
YYGVVCNAGITADNPFPALTEDDWDSVVHTNLDGFYNVLHPLVMPMIRRRKPGRIVTIASMSGVIGNRGQVNYSAAKAGV
IGATKALAIELAKRHITVNCVAPGWIDTDMTHHLPQEEVRKLIPMRRTGQAEDVAGVVSFLCSSDAAYMTRQVLPVNGGM
C
>Mature_241_residues
MNDTILVTGANRGIGRATALRLARDGFDIVVHYRSREQEAEAVAEDIRALGREARLLRFDVAERGEARACLEADIERHGA
YYGVVCNAGITADNPFPALTEDDWDSVVHTNLDGFYNVLHPLVMPMIRRRKPGRIVTIASMSGVIGNRGQVNYSAAKAGV
IGATKALAIELAKRHITVNCVAPGWIDTDMTHHLPQEEVRKLIPMRRTGQAEDVAGVVSFLCSSDAAYMTRQVLPVNGGM
C

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=39.8406374501992, Blast_Score=147, Evalue=6e-36,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=38.5892116182573, Blast_Score=136, Evalue=2e-32,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=35.4581673306773, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI5031737, Length=246, Percent_Identity=31.7073170731707, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=32.5490196078431, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4504505, Length=227, Percent_Identity=36.1233480176211, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=29.1497975708502, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=30.7692307692308, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=28.9156626506024, Blast_Score=77, Evalue=9e-15,
Organism=Homo sapiens, GI59889578, Length=208, Percent_Identity=31.7307692307692, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=28.6307053941909, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI126723191, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=243, Percent_Identity=30.0411522633745, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657478, Length=196, Percent_Identity=29.5918367346939, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI210032110, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4758504, Length=205, Percent_Identity=29.2682926829268, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4503301, Length=207, Percent_Identity=26.5700483091787, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=242, Percent_Identity=42.1487603305785, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=33.6065573770492, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=34.1463414634146, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=31.0483870967742, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790717, Length=252, Percent_Identity=30.952380952381, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=32.3651452282158, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1789208, Length=239, Percent_Identity=32.6359832635983, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787905, Length=238, Percent_Identity=31.5126050420168, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789378, Length=244, Percent_Identity=30.7377049180328, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=29.4820717131474, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=29.8319327731092, Blast_Score=87, Evalue=7e-19,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=28.515625, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=27.8606965174129, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787526, Length=209, Percent_Identity=28.7081339712919, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=239, Percent_Identity=35.5648535564854, Blast_Score=133, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25147288, Length=239, Percent_Identity=35.5648535564854, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17568967, Length=207, Percent_Identity=35.2657004830918, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=248, Percent_Identity=31.0483870967742, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=245, Percent_Identity=29.3877551020408, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=28.9795918367347, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=27.2357723577236, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=233, Percent_Identity=27.0386266094421, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=26.7175572519084, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=29.6296296296296, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17536025, Length=245, Percent_Identity=25.7142857142857, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=255, Percent_Identity=27.843137254902, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=247, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=24.3137254901961, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=255, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=24.609375, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=26.8199233716475, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=24.8062015503876, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=26.1538461538462, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=27.2, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=26.6932270916335, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=211, Percent_Identity=35.5450236966825, Blast_Score=101, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324126, Length=215, Percent_Identity=28.8372093023256, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=218, Percent_Identity=24.7706422018349, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=241, Percent_Identity=36.0995850622407, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=35.655737704918, Blast_Score=124, Evalue=5e-29,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=30.952380952381, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=30.1204819277108, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=31.3492063492063, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=31.1740890688259, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI18859837, Length=225, Percent_Identity=31.5555555555556, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24643142, Length=241, Percent_Identity=30.7053941908714, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=31.6239316239316, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=28.7958115183246, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=26.5957446808511, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR011285
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26296; Mature: 26296

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTILVTGANRGIGRATALRLARDGFDIVVHYRSREQEAEAVAEDIRALGREARLLRFD
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
VAERGEARACLEADIERHGAYYGVVCNAGITADNPFPALTEDDWDSVVHTNLDGFYNVLH
CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHH
PLVMPMIRRRKPGRIVTIASMSGVIGNRGQVNYSAAKAGVIGATKALAIELAKRHITVNC
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHEEEEEE
VAPGWIDTDMTHHLPQEEVRKLIPMRRTGQAEDVAGVVSFLCSSDAAYMTRQVLPVNGGM
ECCCCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHEEECCCCCC
C
C
>Mature Secondary Structure
MNDTILVTGANRGIGRATALRLARDGFDIVVHYRSREQEAEAVAEDIRALGREARLLRFD
CCCCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHEEEEE
VAERGEARACLEADIERHGAYYGVVCNAGITADNPFPALTEDDWDSVVHTNLDGFYNVLH
CCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHH
PLVMPMIRRRKPGRIVTIASMSGVIGNRGQVNYSAAKAGVIGATKALAIELAKRHITVNC
HHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHEEEEEE
VAPGWIDTDMTHHLPQEEVRKLIPMRRTGQAEDVAGVVSFLCSSDAAYMTRQVLPVNGGM
ECCCCCCCCHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHHEEECCCCCC
C
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9020051 [H]