Click here to switch to the map view.

The map label for this gene is fabF [H]

Identifier: 92114876

GI number: 92114876

Start: 3090196

End: 3091386

Strand: Direct

Name: fabF [H]

Synonym: Csal_2758

Alternate gene names: 92114876

Gene position: 3090196-3091386 (Clockwise)

Preceding gene: 92114875

Following gene: 92114877

Centisome position: 83.59

GC content: 70.45

Gene sequence:

>1191_bases
ATGAGCGTACCGTCTTCCCGACAAGCGTGCCGACTGTCCCGCCCCGGCGTCGTGTGCAGTCTCGGCGACGATCTCGACGT
CATCGCCGAGGCGCTTTTCCAGGGACGCCGCGGACTGACCATCAGCGACGCCTTCACCCCCGGCCGCGACCTGCCGCTGG
GCAGCGTCACATGTTCGCTGCCCGATTGGGACAGCTGGCCATTCGAACAGCGCAGTCGCAACAACCGCCTGCTGGCACTG
GCCCTGCAGCGGCTCGAGGACAGCCTGGCGCCGCTGCGTGAGCGCATCGCGCCGGAACGCATTGGCGTGGTCATCGGCAC
CAGCACCTCGGGCATCGGCGAAACCGAGAGCGCCATCGCCGCAGCGGGCCACGACGGTCCGCTGCCCGACACGTTCCGCT
ACGCCAACCAGGAACTCGGCGCGCCGGCACGCTTCGTGGCCGACCGCCTCGGCGTCAGCGGGCCGGCCTACGCCCTCTCC
ACGGCGTGCAGCTCGAGCGCGCGGGCACTGGCCAGTGCCCGCCGCCTGCTCGCCAGCGGCGCCTGCGACGCCGTGATCGC
CGGCGGTGCGGACAGCCTGTGTCGCCTGACCGTCAACGGCTTCGCGAGTCTGGAGGCGATCAGCGAACGTCCCTGCCTGC
CGTTTTCCGAGCATCGCGACGGCATCAACATCGGCGAGGCGGCAGCCTTGTTCGTGGTCACGCCGGACGAGGGCGGCATC
CAGCTCGCCGGCGTGGGCGAATCCAGCGACGCCTACCACATCTCCGCCCCGCGGCCCGACGGCAGCGGCGCACACGAGGC
GATGCGCCAGGCCCTGGCCACGGCCCATTGCGCCCCCGAGGCCGTGGACTACCTCAATCTGCATGGCACCGGCACGCCCC
ACAACGACAGCATGGAAGCCAGGGCGGTGACGACACTGTTCGAGACACCGCCGCCGTGCAGCTCCACCAAGGGGCTCACC
GGTCATACGCTGGGCGCCGCCGGGGCGCTCGAAGCCGCCTTCTGCTGGCTGGCGCTGACACGCCAGCAGCGGCCGGTGCA
TGTCTTCGACGGCCATCCCGATCCCGAGCTGCCATGGCTCGACCTGGTGACGCCCGAACGCGCTGCCAGCCGCATGCGCT
ACGCGCTGAGCAATTCCTTCGCCTTCGGCGGCAACAATGCCGCCTTGTTGCTGATGCGCGAGGAGGCCTGA

Upstream 100 bases:

>100_bases
GGCGGGATGCCTCGCGGGAGGTCGTGCTCGACGACTTCCAGGGCGACTACCGACTACGCATCACGCCCCTCGATGCCACC
CCCGACCACGAGACCGCCCC

Downstream 100 bases:

>100_bases
CATGCAGACCGACACGCCCTGCGCCATCGAGCCGCTGGTGCCGCATCGCGGTGCGATGTGTCTGCTCGACACCCTGCTGC
ACTACGATGCCGACGGCGCC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSVPSSRQACRLSRPGVVCSLGDDLDVIAEALFQGRRGLTISDAFTPGRDLPLGSVTCSLPDWDSWPFEQRSRNNRLLAL
ALQRLEDSLAPLRERIAPERIGVVIGTSTSGIGETESAIAAAGHDGPLPDTFRYANQELGAPARFVADRLGVSGPAYALS
TACSSSARALASARRLLASGACDAVIAGGADSLCRLTVNGFASLEAISERPCLPFSEHRDGINIGEAAALFVVTPDEGGI
QLAGVGESSDAYHISAPRPDGSGAHEAMRQALATAHCAPEAVDYLNLHGTGTPHNDSMEARAVTTLFETPPPCSSTKGLT
GHTLGAAGALEAAFCWLALTRQQRPVHVFDGHPDPELPWLDLVTPERAASRMRYALSNSFAFGGNNAALLLMREEA

Sequences:

>Translated_396_residues
MSVPSSRQACRLSRPGVVCSLGDDLDVIAEALFQGRRGLTISDAFTPGRDLPLGSVTCSLPDWDSWPFEQRSRNNRLLAL
ALQRLEDSLAPLRERIAPERIGVVIGTSTSGIGETESAIAAAGHDGPLPDTFRYANQELGAPARFVADRLGVSGPAYALS
TACSSSARALASARRLLASGACDAVIAGGADSLCRLTVNGFASLEAISERPCLPFSEHRDGINIGEAAALFVVTPDEGGI
QLAGVGESSDAYHISAPRPDGSGAHEAMRQALATAHCAPEAVDYLNLHGTGTPHNDSMEARAVTTLFETPPPCSSTKGLT
GHTLGAAGALEAAFCWLALTRQQRPVHVFDGHPDPELPWLDLVTPERAASRMRYALSNSFAFGGNNAALLLMREEA
>Mature_395_residues
SVPSSRQACRLSRPGVVCSLGDDLDVIAEALFQGRRGLTISDAFTPGRDLPLGSVTCSLPDWDSWPFEQRSRNNRLLALA
LQRLEDSLAPLRERIAPERIGVVIGTSTSGIGETESAIAAAGHDGPLPDTFRYANQELGAPARFVADRLGVSGPAYALST
ACSSSARALASARRLLASGACDAVIAGGADSLCRLTVNGFASLEAISERPCLPFSEHRDGINIGEAAALFVVTPDEGGIQ
LAGVGESSDAYHISAPRPDGSGAHEAMRQALATAHCAPEAVDYLNLHGTGTPHNDSMEARAVTTLFETPPPCSSTKGLTG
HTLGAAGALEAAFCWLALTRQQRPVHVFDGHPDPELPWLDLVTPERAASRMRYALSNSFAFGGNNAALLLMREEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=265, Percent_Identity=39.2452830188679, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI223972627, Length=147, Percent_Identity=42.8571428571429, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI41872631, Length=313, Percent_Identity=29.073482428115, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1787337, Length=262, Percent_Identity=38.9312977099237, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1788663, Length=404, Percent_Identity=29.2079207920792, Blast_Score=123, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=403, Percent_Identity=29.0322580645161, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71983535, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=255, Percent_Identity=29.0196078431373, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=327, Percent_Identity=23.5474006116208, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320904, Length=273, Percent_Identity=31.5018315018315, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644341, Length=265, Percent_Identity=37.7358490566038, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19920632, Length=312, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221330659, Length=312, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581345, Length=255, Percent_Identity=25.4901960784314, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 41620; Mature: 41489

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPSSRQACRLSRPGVVCSLGDDLDVIAEALFQGRRGLTISDAFTPGRDLPLGSVTCSL
CCCCCCCCHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEECC
PDWDSWPFEQRSRNNRLLALALQRLEDSLAPLRERIAPERIGVVIGTSTSGIGETESAIA
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHE
AAGHDGPLPDTFRYANQELGAPARFVADRLGVSGPAYALSTACSSSARALASARRLLASG
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ACDAVIAGGADSLCRLTVNGFASLEAISERPCLPFSEHRDGINIGEAAALFVVTPDEGGI
CCCEEEECCCCCEEEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCE
QLAGVGESSDAYHISAPRPDGSGAHEAMRQALATAHCAPEAVDYLNLHGTGTPHNDSMEA
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCHH
RAVTTLFETPPPCSSTKGLTGHTLGAAGALEAAFCWLALTRQQRPVHVFDGHPDPELPWL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEE
DLVTPERAASRMRYALSNSFAFGGNNAALLLMREEA
ECCCHHHHHHHHHHHHHCCEEECCCCEEEEEEECCC
>Mature Secondary Structure 
SVPSSRQACRLSRPGVVCSLGDDLDVIAEALFQGRRGLTISDAFTPGRDLPLGSVTCSL
CCCCCCCHHCCCCCCEEEECCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCEEECC
PDWDSWPFEQRSRNNRLLALALQRLEDSLAPLRERIAPERIGVVIGTSTSGIGETESAIA
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCHHHHE
AAGHDGPLPDTFRYANQELGAPARFVADRLGVSGPAYALSTACSSSARALASARRLLASG
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ACDAVIAGGADSLCRLTVNGFASLEAISERPCLPFSEHRDGINIGEAAALFVVTPDEGGI
CCCEEEECCCCCEEEEEECCHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEEEECCCCCE
QLAGVGESSDAYHISAPRPDGSGAHEAMRQALATAHCAPEAVDYLNLHGTGTPHNDSMEA
EEEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHEEEECCCCCCCCCCCHH
RAVTTLFETPPPCSSTKGLTGHTLGAAGALEAAFCWLALTRQQRPVHVFDGHPDPELPWL
HHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEE
DLVTPERAASRMRYALSNSFAFGGNNAALLLMREEA
ECCCHHHHHHHHHHHHHCCEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]