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The map label for this gene is fhuG [H]

Identifier: 92114819

GI number: 92114819

Start: 3028310

End: 3029434

Strand: Direct

Name: fhuG [H]

Synonym: Csal_2701

Alternate gene names: 92114819

Gene position: 3028310-3029434 (Clockwise)

Preceding gene: 92114818

Following gene: 92114820

Centisome position: 81.92

GC content: 70.4

Gene sequence:

>1125_bases
ATGTCCGACGCTTCATTCACGACACCTTCCGCGGGCCACGCCATGACGTCCCCCGTCGACGCTTCGAACGCGGTGCGCCA
GGACAAGTACTACCTCGCGTTGCCACTGGGCCAGCGCCCTCCCCTGCGCGTGATCGTCGACAAGCGCAACCTGCTCGCCA
ACCTGCTGTTGCTGGGGCTTCTGCTGATGCTGGCAGGCGTCTCGCTGAACACCGGCAGCGCCGCCTCGTTGTCGCTGCCG
GCGACGCTGCGCGCCCTGTTCGGAGAAGGCGACCCGCTCGACATCTTCGTGATCCGCGACTTGCGTCTGCCTCGGGTGGT
TGCCGGCATCGCCACGGGAGGTGCCTTTGCCCTGGCCGGCTGCCTGATGCAGACCGTCGCGCGCAACCGCCTGGCCACGC
CAGGGATCGTCGGCCTCGACAACGGCGCCACCGCTTTCGCCGTGGCCTCCGTGGTGGGCGCCGGCATCAGCCTGGCCCCG
CCGGCGATGGCCTTGACCGGCGCCGCCGTCGCCGCGGCGCTCACCTTCGGCTTGACGGGCCGCATCGGCGTGCGCGGGTA
TCGCTTTCTGGTCGCCGGCATCGGCGTCGGCGCCGTCTTTGGCGCCCTCACCCAGCTCATGCTGACGCGCGTCTCCATCG
ACGCCGCCAATGCGGCCTACCCGTGGACGGTGGGGAGTCTCAACGCACGCCCCGATCACGCGGTGCTGAGCCTGTCGCTG
GCCCTGCCGCCTGCCTTGCTGGCTGGCATCTGGCTGACCCGCTCGCTGACCGTGCTGCGACTTTCCGATGCCGTTGCCAC
CGGCCTGGGTGTCGCGGCGAGTCGTTGTCGAATGATCGCTCTCGGCATCGCGGTGATCCTGACCGGCCTGGCCGTGGCGG
TGGCAGGCCCGGTGGGCATGGTGGCGCTGATCGGCCCCGAGTTCGCGCGCCAGCTGAGTGCCCGGAACACCGTTCCCGTG
GTCGGCGCGACCCTGGCCGGCGCCGTGGTCATGGTCGCCGCCGACCTGCTCGGGCGCGTGCTGCTCGCGCCCATCGAGAT
CCCCGTGGGGATCGTCACCGCCCTGATCGGCAGCCCGCTGCTGCTGTGGATACTCTTGAATCCCAACGCCAGGACCGCGC
CATGA

Upstream 100 bases:

>100_bases
CCCTCCGAACTCCCGCTGGGCGTGCTCACGGCGCTGATCGGCGCCCCCGTGCTGATCGGCGTGGTACGTGGCCGCCGGCT
GCCGACGCTATAGGCCGCAC

Downstream 100 bases:

>100_bases
CACACGACATATCCGCCGGCGAGCGCGACGCTACCCGGCCCGACACGCCCTCGGCCACACCAGCACCGGAGATGACGGTA
CGGGATCTGTCGCTGTCCTA

Product: transport system permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSDASFTTPSAGHAMTSPVDASNAVRQDKYYLALPLGQRPPLRVIVDKRNLLANLLLLGLLLMLAGVSLNTGSAASLSLP
ATLRALFGEGDPLDIFVIRDLRLPRVVAGIATGGAFALAGCLMQTVARNRLATPGIVGLDNGATAFAVASVVGAGISLAP
PAMALTGAAVAAALTFGLTGRIGVRGYRFLVAGIGVGAVFGALTQLMLTRVSIDAANAAYPWTVGSLNARPDHAVLSLSL
ALPPALLAGIWLTRSLTVLRLSDAVATGLGVAASRCRMIALGIAVILTGLAVAVAGPVGMVALIGPEFARQLSARNTVPV
VGATLAGAVVMVAADLLGRVLLAPIEIPVGIVTALIGSPLLLWILLNPNARTAP

Sequences:

>Translated_374_residues
MSDASFTTPSAGHAMTSPVDASNAVRQDKYYLALPLGQRPPLRVIVDKRNLLANLLLLGLLLMLAGVSLNTGSAASLSLP
ATLRALFGEGDPLDIFVIRDLRLPRVVAGIATGGAFALAGCLMQTVARNRLATPGIVGLDNGATAFAVASVVGAGISLAP
PAMALTGAAVAAALTFGLTGRIGVRGYRFLVAGIGVGAVFGALTQLMLTRVSIDAANAAYPWTVGSLNARPDHAVLSLSL
ALPPALLAGIWLTRSLTVLRLSDAVATGLGVAASRCRMIALGIAVILTGLAVAVAGPVGMVALIGPEFARQLSARNTVPV
VGATLAGAVVMVAADLLGRVLLAPIEIPVGIVTALIGSPLLLWILLNPNARTAP
>Mature_373_residues
SDASFTTPSAGHAMTSPVDASNAVRQDKYYLALPLGQRPPLRVIVDKRNLLANLLLLGLLLMLAGVSLNTGSAASLSLPA
TLRALFGEGDPLDIFVIRDLRLPRVVAGIATGGAFALAGCLMQTVARNRLATPGIVGLDNGATAFAVASVVGAGISLAPP
AMALTGAAVAAALTFGLTGRIGVRGYRFLVAGIGVGAVFGALTQLMLTRVSIDAANAAYPWTVGSLNARPDHAVLSLSLA
LPPALLAGIWLTRSLTVLRLSDAVATGLGVAASRCRMIALGIAVILTGLAVAVAGPVGMVALIGPEFARQLSARNTVPVV
GATLAGAVVMVAADLLGRVLLAPIEIPVGIVTALIGSPLLLWILLNPNARTAP

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786804, Length=335, Percent_Identity=31.6417910447761, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790740, Length=301, Percent_Identity=32.5581395348837, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790741, Length=313, Percent_Identity=33.2268370607029, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786805, Length=302, Percent_Identity=36.0927152317881, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786347, Length=330, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=33.4519572953737, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37807; Mature: 37676

Theoretical pI: Translated: 11.38; Mature: 11.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDASFTTPSAGHAMTSPVDASNAVRQDKYYLALPLGQRPPLRVIVDKRNLLANLLLLGL
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHH
LLMLAGVSLNTGSAASLSLPATLRALFGEGDPLDIFVIRDLRLPRVVAGIATGGAFALAG
HHHHCCCCCCCCCCCEEECHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHH
CLMQTVARNRLATPGIVGLDNGATAFAVASVVGAGISLAPPAMALTGAAVAAALTFGLTG
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
RIGVRGYRFLVAGIGVGAVFGALTQLMLTRVSIDAANAAYPWTVGSLNARPDHAVLSLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEH
ALPPALLAGIWLTRSLTVLRLSDAVATGLGVAASRCRMIALGIAVILTGLAVAVAGPVGM
HCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VALIGPEFARQLSARNTVPVVGATLAGAVVMVAADLLGRVLLAPIEIPVGIVTALIGSPL
HHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCE
LLWILLNPNARTAP
EEEEEECCCCCCCC
>Mature Secondary Structure 
SDASFTTPSAGHAMTSPVDASNAVRQDKYYLALPLGQRPPLRVIVDKRNLLANLLLLGL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHH
LLMLAGVSLNTGSAASLSLPATLRALFGEGDPLDIFVIRDLRLPRVVAGIATGGAFALAG
HHHHCCCCCCCCCCCEEECHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHH
CLMQTVARNRLATPGIVGLDNGATAFAVASVVGAGISLAPPAMALTGAAVAAALTFGLTG
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCC
RIGVRGYRFLVAGIGVGAVFGALTQLMLTRVSIDAANAAYPWTVGSLNARPDHAVLSLSL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCEEEEEEH
ALPPALLAGIWLTRSLTVLRLSDAVATGLGVAASRCRMIALGIAVILTGLAVAVAGPVGM
HCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
VALIGPEFARQLSARNTVPVVGATLAGAVVMVAADLLGRVLLAPIEIPVGIVTALIGSPL
HHHCCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCE
LLWILLNPNARTAP
EEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]