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The map label for this gene is betT [H]

Identifier: 92114763

GI number: 92114763

Start: 2955810

End: 2957864

Strand: Direct

Name: betT [H]

Synonym: Csal_2645

Alternate gene names: 92114763

Gene position: 2955810-2957864 (Clockwise)

Preceding gene: 92114761

Following gene: 92114767

Centisome position: 79.96

GC content: 61.75

Gene sequence:

>2055_bases
ATGCCTCTACAACACACCGACGACGTCAGTCGCGATCGCCTCAATCCGGCGGTCTTCTTCAGTTCGGCGATCGGCATCGT
GCTCTTCGCGCTATGGACGATGTTCTTCACCGACTCGGCCAGTGGCGTGATCAATGCCGTGCTGGGATGGATCTCCGACT
CTTTCGGCTGGTACTACTTTCTGGCCGTGGTCGCCTACCTGGTCTTCGTGATCGCCATCGGCCTATCACGCTTCGGCAAG
ATCAAGCTGGGACCGGATCATTCCACGCCCGATTTCAACATGGCCTCATGGGCGGCCATGCTCTTCTCGGCGGGCATCGG
CATCGACCTGCTGTTCTTCTGCATCGCGGAGCCGGTATCGCAGTTCCTGGCGCCGCCTCAGGGAGACGGCAACACGGTGG
AAGCCGCACGTCACGCCATGCAGTTGACGTTCCTGCACTGGGGGCTTTCCGGCTGGGGCATCTACACCCTGGTGGGGATG
TCGCTGGCGTTCTTCAGCTATCGGCACAATCTGCCGCTGACCATCCGCAGCGCACTCTATCCGATCTTCGGCAAGAAGAT
TCACGGTCCCATCGGCCATACCGTGGATACCGCCGCCGTTCTGGGCACGGTATTCGGCATCGCCACCAGCCTGGGGATCG
GCGTCATCCAGCTCAATTTCGGTCTCAACTACATGTTCTCGATTCCCGAGAACACCCTGGTGCAGGCCGCACTGGTGATC
ATGATCGTGTTCTTCGCCACCGTCTCCGCCGTCACCGGGGTCGAGAAGGGCATCCGCCGCCTTTCCGAGTTCAACATGCT
GTTGGCGCTGTTGTTGCTGCTGTTCGTGCTCTTCAGCGGCAAGACCCTGTTTCTGCTCAACGCGCTGGTGCTCAACGTCG
GCGACTATTTCTCCGACTTCATCAGCCTGTCGATGAATACCTACGCCTTCGATCCGCCCACCGCCTGGCTCAATGGCTGG
ACGATCTTCTTCTGGGCCTGGTGGATTGCCTGGGGGCCGTTCGTGGGACTCTTCCTGGCGCGCATCTCCCGCGGCCGCAC
CATTCGTGAATTCGTCGCCGGCACGCTGATGCTGCCGCTGGTCTTCATGATGGCGTGGATGTCGATCATGGGGAACAGCG
CCATCGACATGGTCATGAACGGCGCGGCGGACTTCGGCGATGCGGCGATGAACACGCCGGCCTCCTCCATTTACCTGTTC
CTCGAGTCACTGCCGTGGACCGGGCTGACGACCATCGTCACCACCATTCTGGCCATCGTGTTCTTCGTGACCTCCGGCGA
CTCCGGGGCGCTGGTACTCTCCAACTTCACGTCCAGGCTCAAGGACGTGAACAGCGACGCACCGATCTGGATGCGCATCC
TCTGGGCCTGCGTGATCGGCCTGCTCACCCTGGCGCTATTGATGGCCGGCGGCTTGTCGGCACTGCAGAGCGTGGTGGTC
ATCACCGGGCTGCCGTTCTCCATCGTGCTGTTCTTCATGATGGCGGGGCTGTTCAAGGCCCTGCGAGTGGAAGGCTTCAA
GGAAGACAGTCACCGCGCGAGCCTGGCCGGCCACCTTTCCAGCCGCACCGGCGCGGCAGAACGTACGCCACGTGGCTGGC
GTCAGCGCCTGGGCCGTGCCATGAGCTTCCCGGGCAGCAAGCAGGCACGCCGCTTCCTCGATGAGGTAGGCAAACCGGCC
ATGCAGGACGTCAGTCAGGCGTTGAGCCAACAGGGCGTCGAGGTCGAGGTCGTCGAAGAAGACGGCGACGACCCGCATCT
GGCTCTCAACGTCGGTCTCGGCGACGAGCAGAACTTCACCTATCAGATCTGGCCACGCCGGTTCGCGACCCCCTCGTTCG
CACTGCGCGCCCAGCAGGCCAATGCCTATTACTATCGCCTGGAGGTCTACCTTCTCGAAGGCAGCCAGGGGTATGACCTG
ATGGGCTACAGCAAGGAACAGGTCATCGAGGACATTCTCGATCAGTACGAACGTCACCTGCACTTCCTGCACATGAACCG
GGAAGCACCAGGCAACGTGACCATGCCGGACAGCCCCGAACAACCGCCGGCATGA

Upstream 100 bases:

>100_bases
GCCACATCGCGTTTTCACGCAACTTGGCCATAGTGAAGAAGGATGTGCCGTGACATGACGTCACGCTACTGCCGCGCTTA
CGACAACTCGAGGATCGCTC

Downstream 100 bases:

>100_bases
CCGTGAAACGGGCCATTTTCCGGCCATGACGCGAGCAGGGGCGCATCCAGGATGCGCCCCTTTTTTATTGGCCCACGCTT
CAGGGCCGCACGTCATTGCG

Product: choline transport protein BetT

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 684; Mature: 683

Protein sequence:

>684_residues
MPLQHTDDVSRDRLNPAVFFSSAIGIVLFALWTMFFTDSASGVINAVLGWISDSFGWYYFLAVVAYLVFVIAIGLSRFGK
IKLGPDHSTPDFNMASWAAMLFSAGIGIDLLFFCIAEPVSQFLAPPQGDGNTVEAARHAMQLTFLHWGLSGWGIYTLVGM
SLAFFSYRHNLPLTIRSALYPIFGKKIHGPIGHTVDTAAVLGTVFGIATSLGIGVIQLNFGLNYMFSIPENTLVQAALVI
MIVFFATVSAVTGVEKGIRRLSEFNMLLALLLLLFVLFSGKTLFLLNALVLNVGDYFSDFISLSMNTYAFDPPTAWLNGW
TIFFWAWWIAWGPFVGLFLARISRGRTIREFVAGTLMLPLVFMMAWMSIMGNSAIDMVMNGAADFGDAAMNTPASSIYLF
LESLPWTGLTTIVTTILAIVFFVTSGDSGALVLSNFTSRLKDVNSDAPIWMRILWACVIGLLTLALLMAGGLSALQSVVV
ITGLPFSIVLFFMMAGLFKALRVEGFKEDSHRASLAGHLSSRTGAAERTPRGWRQRLGRAMSFPGSKQARRFLDEVGKPA
MQDVSQALSQQGVEVEVVEEDGDDPHLALNVGLGDEQNFTYQIWPRRFATPSFALRAQQANAYYYRLEVYLLEGSQGYDL
MGYSKEQVIEDILDQYERHLHFLHMNREAPGNVTMPDSPEQPPA

Sequences:

>Translated_684_residues
MPLQHTDDVSRDRLNPAVFFSSAIGIVLFALWTMFFTDSASGVINAVLGWISDSFGWYYFLAVVAYLVFVIAIGLSRFGK
IKLGPDHSTPDFNMASWAAMLFSAGIGIDLLFFCIAEPVSQFLAPPQGDGNTVEAARHAMQLTFLHWGLSGWGIYTLVGM
SLAFFSYRHNLPLTIRSALYPIFGKKIHGPIGHTVDTAAVLGTVFGIATSLGIGVIQLNFGLNYMFSIPENTLVQAALVI
MIVFFATVSAVTGVEKGIRRLSEFNMLLALLLLLFVLFSGKTLFLLNALVLNVGDYFSDFISLSMNTYAFDPPTAWLNGW
TIFFWAWWIAWGPFVGLFLARISRGRTIREFVAGTLMLPLVFMMAWMSIMGNSAIDMVMNGAADFGDAAMNTPASSIYLF
LESLPWTGLTTIVTTILAIVFFVTSGDSGALVLSNFTSRLKDVNSDAPIWMRILWACVIGLLTLALLMAGGLSALQSVVV
ITGLPFSIVLFFMMAGLFKALRVEGFKEDSHRASLAGHLSSRTGAAERTPRGWRQRLGRAMSFPGSKQARRFLDEVGKPA
MQDVSQALSQQGVEVEVVEEDGDDPHLALNVGLGDEQNFTYQIWPRRFATPSFALRAQQANAYYYRLEVYLLEGSQGYDL
MGYSKEQVIEDILDQYERHLHFLHMNREAPGNVTMPDSPEQPPA
>Mature_683_residues
PLQHTDDVSRDRLNPAVFFSSAIGIVLFALWTMFFTDSASGVINAVLGWISDSFGWYYFLAVVAYLVFVIAIGLSRFGKI
KLGPDHSTPDFNMASWAAMLFSAGIGIDLLFFCIAEPVSQFLAPPQGDGNTVEAARHAMQLTFLHWGLSGWGIYTLVGMS
LAFFSYRHNLPLTIRSALYPIFGKKIHGPIGHTVDTAAVLGTVFGIATSLGIGVIQLNFGLNYMFSIPENTLVQAALVIM
IVFFATVSAVTGVEKGIRRLSEFNMLLALLLLLFVLFSGKTLFLLNALVLNVGDYFSDFISLSMNTYAFDPPTAWLNGWT
IFFWAWWIAWGPFVGLFLARISRGRTIREFVAGTLMLPLVFMMAWMSIMGNSAIDMVMNGAADFGDAAMNTPASSIYLFL
ESLPWTGLTTIVTTILAIVFFVTSGDSGALVLSNFTSRLKDVNSDAPIWMRILWACVIGLLTLALLMAGGLSALQSVVVI
TGLPFSIVLFFMMAGLFKALRVEGFKEDSHRASLAGHLSSRTGAAERTPRGWRQRLGRAMSFPGSKQARRFLDEVGKPAM
QDVSQALSQQGVEVEVVEEDGDDPHLALNVGLGDEQNFTYQIWPRRFATPSFALRAQQANAYYYRLEVYLLEGSQGYDLM
GYSKEQVIEDILDQYERHLHFLHMNREAPGNVTMPDSPEQPPA

Specific function: High-affinity uptake of choline driven by a proton- motive force [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=681, Percent_Identity=55.5066079295154, Blast_Score=789, Evalue=0.0,
Organism=Escherichia coli, GI1788102, Length=470, Percent_Identity=28.2978723404255, Blast_Score=185, Evalue=9e-48,
Organism=Escherichia coli, GI1786224, Length=495, Percent_Identity=26.2626262626263, Blast_Score=164, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 75463; Mature: 75331

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLQHTDDVSRDRLNPAVFFSSAIGIVLFALWTMFFTDSASGVINAVLGWISDSFGWYYF
CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
LAVVAYLVFVIAIGLSRFGKIKLGPDHSTPDFNMASWAAMLFSAGIGIDLLFFCIAEPVS
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QFLAPPQGDGNTVEAARHAMQLTFLHWGLSGWGIYTLVGMSLAFFSYRHNLPLTIRSALY
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
PIFGKKIHGPIGHTVDTAAVLGTVFGIATSLGIGVIQLNFGLNYMFSIPENTLVQAALVI
HHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHH
MIVFFATVSAVTGVEKGIRRLSEFNMLLALLLLLFVLFSGKTLFLLNALVLNVGDYFSDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ISLSMNTYAFDPPTAWLNGWTIFFWAWWIAWGPFVGLFLARISRGRTIREFVAGTLMLPL
HHHHCCCEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFMMAWMSIMGNSAIDMVMNGAADFGDAAMNTPASSIYLFLESLPWTGLTTIVTTILAIV
HHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
FFVTSGDSGALVLSNFTSRLKDVNSDAPIWMRILWACVIGLLTLALLMAGGLSALQSVVV
HHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ITGLPFSIVLFFMMAGLFKALRVEGFKEDSHRASLAGHLSSRTGAAERTPRGWRQRLGRA
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MSFPGSKQARRFLDEVGKPAMQDVSQALSQQGVEVEVVEEDGDDPHLALNVGLGDEQNFT
HCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCE
YQIWPRRFATPSFALRAQQANAYYYRLEVYLLEGSQGYDLMGYSKEQVIEDILDQYERHL
EEECCHHHCCCHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
HFLHMNREAPGNVTMPDSPEQPPA
HHHEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLQHTDDVSRDRLNPAVFFSSAIGIVLFALWTMFFTDSASGVINAVLGWISDSFGWYYF
CCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHH
LAVVAYLVFVIAIGLSRFGKIKLGPDHSTPDFNMASWAAMLFSAGIGIDLLFFCIAEPVS
HHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
QFLAPPQGDGNTVEAARHAMQLTFLHWGLSGWGIYTLVGMSLAFFSYRHNLPLTIRSALY
HHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
PIFGKKIHGPIGHTVDTAAVLGTVFGIATSLGIGVIQLNFGLNYMFSIPENTLVQAALVI
HHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHH
MIVFFATVSAVTGVEKGIRRLSEFNMLLALLLLLFVLFSGKTLFLLNALVLNVGDYFSDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
ISLSMNTYAFDPPTAWLNGWTIFFWAWWIAWGPFVGLFLARISRGRTIREFVAGTLMLPL
HHHHCCCEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VFMMAWMSIMGNSAIDMVMNGAADFGDAAMNTPASSIYLFLESLPWTGLTTIVTTILAIV
HHHHHHHHHHCCCHHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
FFVTSGDSGALVLSNFTSRLKDVNSDAPIWMRILWACVIGLLTLALLMAGGLSALQSVVV
HHHCCCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ITGLPFSIVLFFMMAGLFKALRVEGFKEDSHRASLAGHLSSRTGAAERTPRGWRQRLGRA
HCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MSFPGSKQARRFLDEVGKPAMQDVSQALSQQGVEVEVVEEDGDDPHLALNVGLGDEQNFT
HCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCE
YQIWPRRFATPSFALRAQQANAYYYRLEVYLLEGSQGYDLMGYSKEQVIEDILDQYERHL
EEECCHHHCCCHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
HFLHMNREAPGNVTMPDSPEQPPA
HHHEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]