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The map label for this gene is dsbG [H]

Identifier: 92114712

GI number: 92114712

Start: 2906525

End: 2907292

Strand: Direct

Name: dsbG [H]

Synonym: Csal_2594

Alternate gene names: 92114712

Gene position: 2906525-2907292 (Clockwise)

Preceding gene: 92114711

Following gene: 92114718

Centisome position: 78.63

GC content: 69.27

Gene sequence:

>768_bases
ATGACGCATTTCCTGCCTGGCGCTCGCCTGGGGCTCATCGTCGCCCTGGGGCTCGGCGGCACCCCCGCGTGGGCGCAACC
CGACGATCTTCCCGCCCCCGTCGAGGCGCTCGTCGCCCAGGGGCTGACGGTGCACGAGCGCTTCGCGGCTCCCGACGGCC
TCACCGGCTATGCCGCCAGCGCGCAGGGCCAGCCGGTGGCGATCTACGTCACCGCGAACGGCCAGCATGCCATCGTCGGC
AATCTCGTCGATGCCGAGGGCAACAACCTGTCGAGCGAGCCGCTCGACGAATTCGTCAAGGGGCCACAGGACGCCGCCGT
CTGGCAACGCCTCGAGGACAGCCACTGGATCCTCGATGGCGACCACAGCGCCCCGCGCACGGTGTACGTCTTCACCGATC
CCAACTGCCCGTACTGCAAGCGTTTCTGGGACGCCGCACGCCCCTGGGTCGAGGCCGGCGAAGTGCAACTGCGGCATGTC
ATGATCGGCGTTCTCGAGTCCGACAGCCCGGCCAAGGCAGCCACGCTGCTGGGCGCCGCCGATCCCGCCGCCGCCTTCAC
GGCACACAATCGCGGCGACGAGGTGGCCCCGTCCGCCCAACCGGCCGATATCGAGCAGCAGGTTCAGGACAACAACACCC
TCATGCGCGAGCTGGGCCTGCGGGGCACGCCGGCGATCGTCTATCGTCGCGACAGCCAGTTGGAGGTCACCCAAGGCATG
CCCGGCGACGACAAGATGCGCGCCGTCATGGGCTCTTCTCGTCCCTGA

Upstream 100 bases:

>100_bases
CGCCGAGGGGCGCCTGGTCGACACGCATTTCGGCGAACTCTCCCAAGCCACACTGACGCAGGCGCTAGCGCGTCTCGCCT
CACCGCAATAGGAGCTTCCC

Downstream 100 bases:

>100_bases
CGGCGGCACGCCGGGCGTCACACGCCGGGCAGTGTCAGGCATGCCTCGAAGCCGCCATGTCGAGGATGCCGAAAGTGCAG
CTCGCCCCCGGCAAGCTCGG

Product: disulfide isomerase/thiol-disulfide oxidase

Products: protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTHFLPGARLGLIVALGLGGTPAWAQPDDLPAPVEALVAQGLTVHERFAAPDGLTGYAASAQGQPVAIYVTANGQHAIVG
NLVDAEGNNLSSEPLDEFVKGPQDAAVWQRLEDSHWILDGDHSAPRTVYVFTDPNCPYCKRFWDAARPWVEAGEVQLRHV
MIGVLESDSPAKAATLLGAADPAAAFTAHNRGDEVAPSAQPADIEQQVQDNNTLMRELGLRGTPAIVYRRDSQLEVTQGM
PGDDKMRAVMGSSRP

Sequences:

>Translated_255_residues
MTHFLPGARLGLIVALGLGGTPAWAQPDDLPAPVEALVAQGLTVHERFAAPDGLTGYAASAQGQPVAIYVTANGQHAIVG
NLVDAEGNNLSSEPLDEFVKGPQDAAVWQRLEDSHWILDGDHSAPRTVYVFTDPNCPYCKRFWDAARPWVEAGEVQLRHV
MIGVLESDSPAKAATLLGAADPAAAFTAHNRGDEVAPSAQPADIEQQVQDNNTLMRELGLRGTPAIVYRRDSQLEVTQGM
PGDDKMRAVMGSSRP
>Mature_254_residues
THFLPGARLGLIVALGLGGTPAWAQPDDLPAPVEALVAQGLTVHERFAAPDGLTGYAASAQGQPVAIYVTANGQHAIVGN
LVDAEGNNLSSEPLDEFVKGPQDAAVWQRLEDSHWILDGDHSAPRTVYVFTDPNCPYCKRFWDAARPWVEAGEVQLRHVM
IGVLESDSPAKAATLLGAADPAAAFTAHNRGDEVAPSAQPADIEQQVQDNNTLMRELGLRGTPAIVYRRDSQLEVTQGMP
GDDKMRAVMGSSRP

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=231, Percent_Identity=40.6926406926407, Blast_Score=199, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27221; Mature: 27090

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHFLPGARLGLIVALGLGGTPAWAQPDDLPAPVEALVAQGLTVHERFAAPDGLTGYAAS
CCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
AQGQPVAIYVTANGQHAIVGNLVDAEGNNLSSEPLDEFVKGPQDAAVWQRLEDSHWILDG
CCCCCEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEC
DHSAPRTVYVFTDPNCPYCKRFWDAARPWVEAGEVQLRHVMIGVLESDSPAKAATLLGAA
CCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCEEEEEEEEEEECCCCCHHHHHHHCCC
DPAAAFTAHNRGDEVAPSAQPADIEQQVQDNNTLMRELGLRGTPAIVYRRDSQLEVTQGM
CCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCEEEEECCCCEEEECCC
PGDDKMRAVMGSSRP
CCHHHHHHHHCCCCC
>Mature Secondary Structure 
THFLPGARLGLIVALGLGGTPAWAQPDDLPAPVEALVAQGLTVHERFAAPDGLTGYAAS
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHCCCCCCCCCCCC
AQGQPVAIYVTANGQHAIVGNLVDAEGNNLSSEPLDEFVKGPQDAAVWQRLEDSHWILDG
CCCCCEEEEEEECCCEEEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEC
DHSAPRTVYVFTDPNCPYCKRFWDAARPWVEAGEVQLRHVMIGVLESDSPAKAATLLGAA
CCCCCEEEEEEECCCCCHHHHHHHHCCCCHHCCCEEEEEEEEEEECCCCCHHHHHHHCCC
DPAAAFTAHNRGDEVAPSAQPADIEQQVQDNNTLMRELGLRGTPAIVYRRDSQLEVTQGM
CCHHHHHCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHCCCCCCEEEEECCCCEEEECCC
PGDDKMRAVMGSSRP
CCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein with reduced SH groups [C]

Specific reaction: protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]