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The map label for this gene is tatD [H]

Identifier: 92114517

GI number: 92114517

Start: 2690667

End: 2691530

Strand: Direct

Name: tatD [H]

Synonym: Csal_2399

Alternate gene names: 92114517

Gene position: 2690667-2691530 (Clockwise)

Preceding gene: 92114515

Following gene: 92114518

Centisome position: 72.79

GC content: 68.87

Gene sequence:

>864_bases
GTGACACGATCTTCCGTGACACAAGACGACGCCAATCCGCTACCCGAAGCGCTGCGCCTGACGCCGCCGTCGCCGCTGGT
CGACATCGGCGCGAACCTGACGCACGAGAGCTTCGCCCGCGACCTCGACGCCGTGCTTGCCCGGGCCCGGCACGCGGGCG
TGGACGACATGATCCTCACCGGCACCGACCTGGCACACAGCGAACAGGCCGCCGACCTCGCCCAACGTCATCCGGGGCTG
TACGCCACCGCCGGCCTGCATCCCCACATGGCGAGCCACTGGAACCCTGAACTGGCGGCGGCCCTGCAGGCATTGCAGGC
GCGGCCCGAGGTCGTGGCCGTGGGCGAATGCGGCCTCGACTTCAACCGCAATTTCTCGACGCCCGCCGAGCAGGAACATG
CCTTCGAAGCGCAGCTCGCGCTCGCCGCCGAAAGCGGCCTGCCGCTGTTCCTGCATGAGCGCGATGCCGGTGCACGCATG
CGTGACATGCTGCGCCATTGGCGTGACGCCATCGGCGACGCCGTGGTTCACTGTTTCACCGCCGACCGCGACACCCTGCA
CGGTTACCTGGATCTCGACCTGCATATCGGGCTGACGGGTTGGCTCTGCGACGAGCGGCGTGGTCATCATCTGCGCGACC
TGGTTGCCGATATCCCCGCCGCGCGCCTGATGGTCGAGACCGACTGCCCCTATCTCCTGCCGCGCAACCTGCCGGCCAAA
CTCAAGGGGCGCCGCCACGAACCGGCGCTGCTGCCCTGGATCGTCCGCGAGATCGCGCACTGGCGCGGCGAGAGCGAGGC
CTCGCTGGCGGCTTCCTCCACCGCCACGGCGCGGCGATTCTTCCGACTCGACGAGGAGCAATGA

Upstream 100 bases:

>100_bases
GACATTCGGAGTAAAGACGCTAGTGTAACGCATGGTCGCCTCCCGGGTCCGGGGGTAGAATGGCGGGTTTTCGCGACTCA
CTGGGCTGGGGAGATTTCCC

Downstream 100 bases:

>100_bases
CATGGATTTTCCCGGTTTCATCGCCATCGAGACCGGCGACGAGGAAGCCCTCCCCGTCGCCATCTCCTGGGCCCTGCCCG
ATGGCCAGATCAAGCATGCG

Product: Sec-independent protein translocase TatD

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MTRSSVTQDDANPLPEALRLTPPSPLVDIGANLTHESFARDLDAVLARARHAGVDDMILTGTDLAHSEQAADLAQRHPGL
YATAGLHPHMASHWNPELAAALQALQARPEVVAVGECGLDFNRNFSTPAEQEHAFEAQLALAAESGLPLFLHERDAGARM
RDMLRHWRDAIGDAVVHCFTADRDTLHGYLDLDLHIGLTGWLCDERRGHHLRDLVADIPAARLMVETDCPYLLPRNLPAK
LKGRRHEPALLPWIVREIAHWRGESEASLAASSTATARRFFRLDEEQ

Sequences:

>Translated_287_residues
MTRSSVTQDDANPLPEALRLTPPSPLVDIGANLTHESFARDLDAVLARARHAGVDDMILTGTDLAHSEQAADLAQRHPGL
YATAGLHPHMASHWNPELAAALQALQARPEVVAVGECGLDFNRNFSTPAEQEHAFEAQLALAAESGLPLFLHERDAGARM
RDMLRHWRDAIGDAVVHCFTADRDTLHGYLDLDLHIGLTGWLCDERRGHHLRDLVADIPAARLMVETDCPYLLPRNLPAK
LKGRRHEPALLPWIVREIAHWRGESEASLAASSTATARRFFRLDEEQ
>Mature_286_residues
TRSSVTQDDANPLPEALRLTPPSPLVDIGANLTHESFARDLDAVLARARHAGVDDMILTGTDLAHSEQAADLAQRHPGLY
ATAGLHPHMASHWNPELAAALQALQARPEVVAVGECGLDFNRNFSTPAEQEHAFEAQLALAAESGLPLFLHERDAGARMR
DMLRHWRDAIGDAVVHCFTADRDTLHGYLDLDLHIGLTGWLCDERRGHHLRDLVADIPAARLMVETDCPYLLPRNLPAKL
KGRRHEPALLPWIVREIAHWRGESEASLAASSTATARRFFRLDEEQ

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=294, Percent_Identity=31.6326530612245, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI225903439, Length=252, Percent_Identity=31.3492063492063, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=32.5242718446602, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI48994985, Length=258, Percent_Identity=51.1627906976744, Blast_Score=271, Evalue=3e-74,
Organism=Escherichia coli, GI1787342, Length=252, Percent_Identity=32.1428571428571, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082439, Length=207, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=38.0782918149466, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=26.7657992565056, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=172, Percent_Identity=31.3953488372093, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=283, Percent_Identity=34.2756183745583, Blast_Score=160, Evalue=7e-40,
Organism=Drosophila melanogaster, GI221330018, Length=259, Percent_Identity=34.7490347490347, Blast_Score=117, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24586117, Length=246, Percent_Identity=34.5528455284553, Blast_Score=110, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 31750; Mature: 31619

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSSVTQDDANPLPEALRLTPPSPLVDIGANLTHESFARDLDAVLARARHAGVDDMILT
CCCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
GTDLAHSEQAADLAQRHPGLYATAGLHPHMASHWNPELAAALQALQARPEVVAVGECGLD
CCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCC
FNRNFSTPAEQEHAFEAQLALAAESGLPLFLHERDAGARMRDMLRHWRDAIGDAVVHCFT
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
ADRDTLHGYLDLDLHIGLTGWLCDERRGHHLRDLVADIPAARLMVETDCPYLLPRNLPAK
CCCCCCCEEEEEEEEECCEEEECCCCCCCHHHHHHHHCCHHHEEEECCCCEECCCCCCHH
LKGRRHEPALLPWIVREIAHWRGESEASLAASSTATARRFFRLDEEQ
HCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TRSSVTQDDANPLPEALRLTPPSPLVDIGANLTHESFARDLDAVLARARHAGVDDMILT
CCCCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEE
GTDLAHSEQAADLAQRHPGLYATAGLHPHMASHWNPELAAALQALQARPEVVAVGECGLD
CCCCHHHHHHHHHHHHCCCCEEECCCCCHHHHCCCHHHHHHHHHHHCCCCEEEEECCCCC
FNRNFSTPAEQEHAFEAQLALAAESGLPLFLHERDAGARMRDMLRHWRDAIGDAVVHCFT
CCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHC
ADRDTLHGYLDLDLHIGLTGWLCDERRGHHLRDLVADIPAARLMVETDCPYLLPRNLPAK
CCCCCCCEEEEEEEEECCEEEECCCCCCCHHHHHHHHCCHHHEEEECCCCEECCCCCCHH
LKGRRHEPALLPWIVREIAHWRGESEASLAASSTATARRFFRLDEEQ
HCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]