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The map label for this gene is codB [H]

Identifier: 92114471

GI number: 92114471

Start: 2641667

End: 2642902

Strand: Direct

Name: codB [H]

Synonym: Csal_2351

Alternate gene names: 92114471

Gene position: 2641667-2642902 (Clockwise)

Preceding gene: 92114470

Following gene: 92114473

Centisome position: 71.46

GC content: 64.0

Gene sequence:

>1236_bases
TTGAGCGAAGTCCCCAGCAGCGAACGCAAAGGGCTGCTCTCCACCTCGGTTGTACTGCTCGGTTTTACCTTTTTCACCGC
CACCATGTGGGCGGGCGGCTCGCTCGGCGTCGCCTTCCCGTTCGGCGAGCTGCTGGGGGTGATTCTTGTCGGCAACCTGC
TGCTGGGCGCCTATGCGGCGGCCCTGGGTTATATCGCCTGCAAGAGCGGCCTCAACTCCGTGCTGATGGGGCGTTTCTGC
TTTGGCGAGGTGGGCAGCAAAGTGTCCGACTTCGTGCTCGGCTTCACCCAGATCGGCTGGTACGCCTGGGGCACCGCCAC
CATCGCCGTGGTCCTGGTCAAGACCACCGGCCTGCCGGAGTCGCTCAAGATTCCGCTGATGGTGCTGTTCGGCTTCGCCT
TTTGCATCACTGCGATGGTCGGCTTTCGCGGACTGGACCTGCTTTCTCGCTTTGCCGTCCCGGCGATGATGCTGTTCATC
CTGATCAGCCTCTACACCGGCATGGTGGATGTCGGCGGGCTTTCCGGCCTTGCGGGCCAGACGCCCTCCGAGAGCATGAG
CTTTGCCGCCGCCATCACCGTGGTGATCGGGACTTTCATCAGCGGCGGCACCCAGGCCACCAACTGGAGTCGTTTCGCCC
GCACCCCGAAGATCGCCGTAATCGCCACGCTGGCCGCCTTCTTCATCGGCAACGGCCTGATGGTGCTGACCGGCGCACTG
GGGGCGATGATCTACCAGCAGGCGGATATCGTCGATGTCATGCTGGCCCAGGGCTTCGTGGTACTTGCCGTGCTGATGCT
GTTCCTCAACATCTGGACCACCCAGGACAACACCATCTACAACTTCGCGGTCGCCGGCTGCAACCTGCTGCGTACCGATA
AACGCAGGGTGGTCACCGTAACCGGCGCCGCCATCGGCACCGTGCTGGCCGTGGGCGGGATGTACAACCTCCTGATTCCG
TTCCTGGTGCTGCTCGGCACCTTCATCCCGCCGATCGGGGGCGTGATCATGGCGGACTTCTGGTGCCGCCATAAGGGCCG
CTATCCGACGCTGAACAGCGCCAACTTGCCCGCCTTCAACTGGACCGGCCTGGCATCCTACGCGGTGGGCTCCGGCATGG
CGTACTTCTCCCCGATCCTGCCGCCGCTGGTGGGCGTCATCGCCGCAGCGCTGTGCTATGCCGTCTTGTCGAAGCTACCG
TTCACGCGCCCCGAGCTGACCCCCTCTGAGCACTGA

Upstream 100 bases:

>100_bases
GATCCCGCACGACTCATGCTAAGGCGTCATCCCTACGCTTCATGCCAGTGCTGCATGCCAACTCTCCGCGGAGCATACGA
TGGAACACTCGGACTACCCT

Downstream 100 bases:

>100_bases
GATGGCGACAGTCGGCGCCGCAGAGCGGCGCCGCGCGAGGCCGGCGTGACTCCGCCCCCGTTTCACTCGGCAGCGGCCCC
GGTCCTCCCGGCAACGGACC

Product: cytosine permease

Products: Proton [Cytoplasm]; cytosine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSEVPSSERKGLLSTSVVLLGFTFFTATMWAGGSLGVAFPFGELLGVILVGNLLLGAYAAALGYIACKSGLNSVLMGRFC
FGEVGSKVSDFVLGFTQIGWYAWGTATIAVVLVKTTGLPESLKIPLMVLFGFAFCITAMVGFRGLDLLSRFAVPAMMLFI
LISLYTGMVDVGGLSGLAGQTPSESMSFAAAITVVIGTFISGGTQATNWSRFARTPKIAVIATLAAFFIGNGLMVLTGAL
GAMIYQQADIVDVMLAQGFVVLAVLMLFLNIWTTQDNTIYNFAVAGCNLLRTDKRRVVTVTGAAIGTVLAVGGMYNLLIP
FLVLLGTFIPPIGGVIMADFWCRHKGRYPTLNSANLPAFNWTGLASYAVGSGMAYFSPILPPLVGVIAAALCYAVLSKLP
FTRPELTPSEH

Sequences:

>Translated_411_residues
MSEVPSSERKGLLSTSVVLLGFTFFTATMWAGGSLGVAFPFGELLGVILVGNLLLGAYAAALGYIACKSGLNSVLMGRFC
FGEVGSKVSDFVLGFTQIGWYAWGTATIAVVLVKTTGLPESLKIPLMVLFGFAFCITAMVGFRGLDLLSRFAVPAMMLFI
LISLYTGMVDVGGLSGLAGQTPSESMSFAAAITVVIGTFISGGTQATNWSRFARTPKIAVIATLAAFFIGNGLMVLTGAL
GAMIYQQADIVDVMLAQGFVVLAVLMLFLNIWTTQDNTIYNFAVAGCNLLRTDKRRVVTVTGAAIGTVLAVGGMYNLLIP
FLVLLGTFIPPIGGVIMADFWCRHKGRYPTLNSANLPAFNWTGLASYAVGSGMAYFSPILPPLVGVIAAALCYAVLSKLP
FTRPELTPSEH
>Mature_410_residues
SEVPSSERKGLLSTSVVLLGFTFFTATMWAGGSLGVAFPFGELLGVILVGNLLLGAYAAALGYIACKSGLNSVLMGRFCF
GEVGSKVSDFVLGFTQIGWYAWGTATIAVVLVKTTGLPESLKIPLMVLFGFAFCITAMVGFRGLDLLSRFAVPAMMLFIL
ISLYTGMVDVGGLSGLAGQTPSESMSFAAAITVVIGTFISGGTQATNWSRFARTPKIAVIATLAAFFIGNGLMVLTGALG
AMIYQQADIVDVMLAQGFVVLAVLMLFLNIWTTQDNTIYNFAVAGCNLLRTDKRRVVTVTGAAIGTVLAVGGMYNLLIPF
LVLLGTFIPPIGGVIMADFWCRHKGRYPTLNSANLPAFNWTGLASYAVGSGMAYFSPILPPLVGVIAAALCYAVLSKLPF
TRPELTPSEH

Specific function: Required for cytosine transport into the cell [H]

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Escherichia coli, GI1786530, Length=408, Percent_Identity=37.7450980392157, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248
- InterPro:   IPR012681 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 43370; Mature: 43239

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SEVPSSERKGLLSTSVVLLGFTFFTATMWAGGSLGVAFPFGELLGVILVGNLLLGAYAA
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ALGYIACKSGLNSVLMGRFCFGEVGSKVSDFVLGFTQIGWYAWGTATIAVVLVKTTGLPE
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCC
SLKIPLMVLFGFAFCITAMVGFRGLDLLSRFAVPAMMLFILISLYTGMVDVGGLSGLAGQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TPSESMSFAAAITVVIGTFISGGTQATNWSRFARTPKIAVIATLAAFFIGNGLMVLTGAL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHH
GAMIYQQADIVDVMLAQGFVVLAVLMLFLNIWTTQDNTIYNFAVAGCNLLRTDKRRVVTV
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEHHHCCHHEECCCCEEEEE
TGAAIGTVLAVGGMYNLLIPFLVLLGTFIPPIGGVIMADFWCRHKGRYPTLNSANLPAFN
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
WTGLASYAVGSGMAYFSPILPPLVGVIAAALCYAVLSKLPFTRPELTPSEH
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; cytosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + cytosine [Periplasm] = Proton [Cytoplasm] + cytosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]