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The map label for this gene is gmhA

Identifier: 92114324

GI number: 92114324

Start: 2479271

End: 2479864

Strand: Direct

Name: gmhA

Synonym: Csal_2202

Alternate gene names: 92114324

Gene position: 2479271-2479864 (Clockwise)

Preceding gene: 92114323

Following gene: 92114325

Centisome position: 67.07

GC content: 60.94

Gene sequence:

>594_bases
ATGGATTTCCAATCACGCATACTCGGCCACTTCAACGCCAGCATCGATGCCAAGACCTATGCCAGCGAGGTTCTGCCTCC
CTTCATCGAAGTCGCGAGCCAGATGATGGTTCAGTGCCTGGTCAGCGAAGGCAAGATTCTCGCCTGTGGCAACGGCGGCA
GTGCCGGTGACAGTCAGCACTTCTCATCCGAGTTGCTCAACCGGTTCGAGCGCGAGCGTCCGAGCCTGCCGGCCCTGGCC
CTGACCACCGACACCTCGACTCTCACTTCGATCGCCAACGACTACAGCTACAACGAGATATTCTCCAAGCAGATACGCGC
CCTGGGCCAACCCGGCGATATCCTGCTGGCCATCTCCACGAGCGGCAACTCCGCCAACGTGGTGCAGGCCATCCAGGCCG
CACACGATCGCGACATGCACATCGTGGCGCTCACCGGGCGCGACGGTGGCGACATGGCCTCGCTGCTCGGCCAGGACGAC
TGCGAAATTCGCGTTCCCTCGACTTCCACGGCACGCATCCAGGAAGTGCATCTGCTCGCGATACACTGCCTGTGCGACTT
GATCGACCAACAACTCTTCGGCAGCACAGAGTAA

Upstream 100 bases:

>100_bases
TCGTTTCGACGTCGTCGGCGTCACCGGCACGCCACCCCATCTGTCGTTCGAGTGGATTCGTTCGGCATTCGACGCCTTTT
GACCCAAGCAAGGCCTACTC

Downstream 100 bases:

>100_bases
GGATACCGTCATGACACGACCGCTCATTCTGACCCTTTTCGTCAGCCTCGCACTCGCCCTGGCCGGCTGCGCCTCGCCCG
CCTCCGACGGACAAGGCGGC

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDFQSRILGHFNASIDAKTYASEVLPPFIEVASQMMVQCLVSEGKILACGNGGSAGDSQHFSSELLNRFERERPSLPALA
LTTDTSTLTSIANDYSYNEIFSKQIRALGQPGDILLAISTSGNSANVVQAIQAAHDRDMHIVALTGRDGGDMASLLGQDD
CEIRVPSTSTARIQEVHLLAIHCLCDLIDQQLFGSTE

Sequences:

>Translated_197_residues
MDFQSRILGHFNASIDAKTYASEVLPPFIEVASQMMVQCLVSEGKILACGNGGSAGDSQHFSSELLNRFERERPSLPALA
LTTDTSTLTSIANDYSYNEIFSKQIRALGQPGDILLAISTSGNSANVVQAIQAAHDRDMHIVALTGRDGGDMASLLGQDD
CEIRVPSTSTARIQEVHLLAIHCLCDLIDQQLFGSTE
>Mature_197_residues
MDFQSRILGHFNASIDAKTYASEVLPPFIEVASQMMVQCLVSEGKILACGNGGSAGDSQHFSSELLNRFERERPSLPALA
LTTDTSTLTSIANDYSYNEIFSKQIRALGQPGDILLAISTSGNSANVVQAIQAAHDRDMHIVALTGRDGGDMASLLGQDD
CEIRVPSTSTARIQEVHLLAIHCLCDLIDQQLFGSTE

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI1789539, Length=191, Percent_Identity=56.5445026178011, Blast_Score=227, Evalue=4e-61,
Organism=Escherichia coli, GI1786416, Length=165, Percent_Identity=46.6666666666667, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GMHA_CHRSD (Q1QVF5)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574252.1
- ProteinModelPortal:   Q1QVF5
- SMR:   Q1QVF5
- STRING:   Q1QVF5
- GeneID:   4026394
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2202
- NMPDR:   fig|290398.4.peg.2966
- eggNOG:   COG0279
- HOGENOM:   HBG671955
- OMA:   HDREMIV
- ProtClustDB:   PRK13936
- BioCyc:   CSAL290398:CSAL_2202-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00067
- InterPro:   IPR020620
- InterPro:   IPR001347

Pfam domain/function: PF01380 SIS

EC number: =5.3.1.28

Molecular weight: Translated: 21200; Mature: 21200

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS51464 SIS

Important sites: BINDING 64-64 BINDING 124-124 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQSRILGHFNASIDAKTYASEVLPPFIEVASQMMVQCLVSEGKILACGNGGSAGDSQH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
FSSELLNRFERERPSLPALALTTDTSTLTSIANDYSYNEIFSKQIRALGQPGDILLAIST
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEC
SGNSANVVQAIQAAHDRDMHIVALTGRDGGDMASLLGQDDCEIRVPSTSTARIQEVHLLA
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHHH
IHCLCDLIDQQLFGSTE
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDFQSRILGHFNASIDAKTYASEVLPPFIEVASQMMVQCLVSEGKILACGNGGSAGDSQH
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHH
FSSELLNRFERERPSLPALALTTDTSTLTSIANDYSYNEIFSKQIRALGQPGDILLAIST
HHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEC
SGNSANVVQAIQAAHDRDMHIVALTGRDGGDMASLLGQDDCEIRVPSTSTARIQEVHLLA
CCCCHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCCEEECCCCCCHHHHHHHHHH
IHCLCDLIDQQLFGSTE
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA