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The map label for this gene is coaE [H]

Identifier: 92114299

GI number: 92114299

Start: 2451031

End: 2451669

Strand: Direct

Name: coaE [H]

Synonym: Csal_2177

Alternate gene names: 92114299

Gene position: 2451031-2451669 (Clockwise)

Preceding gene: 92114298

Following gene: 92114300

Centisome position: 66.3

GC content: 66.51

Gene sequence:

>639_bases
ATGACCACACCCGTACGCATCATCGGGGTGACCGGCGGCATCGCCTCGGGCAAGTCCACCGTCGCCGCCATGTTCGCCGA
ACACGGTATTCCCTGGGTCGACGCGGATCACGTCGCCCGCGATGTCGTCGCCCCCGGCGAGCCGGCGCTCGCGGAGATCG
TCGCGCGCTATGGCCCCTCGCTTGTCGATGACCGCGGCCACTTGCAGCGCCGCGTCCTGCGTGACATCGTCTTCGCCGAT
GATGAGGAGCGACGCTGGCTGGAAAGCGTCACCCACCCGCGCATTCGTCAACGGCTATGCGACACGCTCGACACGATGCG
CCACGGCGATGCCCCTTACGGCCTGCTGGTGTCGCCGTTGCTTTTCGAGACGGACCAGGCCTCGCTGGTCGACCGCTGCC
TGGTCATCGATGTGCCGGAAAAGGTGCAGGTTGCGCGCGTGCGAGCCCGGGATACCGTGAGCGAATCGCAGGCGCATGCT
ATCCTCGCCGCCCAGATGCCACGCCAGGCGCGATTGGCACGGGCCGACGACGTGATCGAAAATGATGGTGACCTGGCATC
GCTCAAGGCGCAGGTCGCCCGGCTCGATGCCCGTTACCGGCAACCTTTGGATGTCCCGGATCAGGAGGATTCGCCCTAG

Upstream 100 bases:

>100_bases
ATGCCGCTGCCCTTCGGCCCCTTCCTCGCCCTCGCCGGCTGGGTGGCGGTCCTCTTCGGCGCACCGCTGCGCGCCTTGAC
CGGTCTATGAGGCACTCGAC

Downstream 100 bases:

>100_bases
CATGACGGATACACCCCAAGACCGCCCCCTCGAGGTCGCCTGCCCACAGTGCCGCACCAAGGTCGCGTGGACGACCGAAA
ACCCCTACCGGCCCTTCTGC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTTPVRIIGVTGGIASGKSTVAAMFAEHGIPWVDADHVARDVVAPGEPALAEIVARYGPSLVDDRGHLQRRVLRDIVFAD
DEERRWLESVTHPRIRQRLCDTLDTMRHGDAPYGLLVSPLLFETDQASLVDRCLVIDVPEKVQVARVRARDTVSESQAHA
ILAAQMPRQARLARADDVIENDGDLASLKAQVARLDARYRQPLDVPDQEDSP

Sequences:

>Translated_212_residues
MTTPVRIIGVTGGIASGKSTVAAMFAEHGIPWVDADHVARDVVAPGEPALAEIVARYGPSLVDDRGHLQRRVLRDIVFAD
DEERRWLESVTHPRIRQRLCDTLDTMRHGDAPYGLLVSPLLFETDQASLVDRCLVIDVPEKVQVARVRARDTVSESQAHA
ILAAQMPRQARLARADDVIENDGDLASLKAQVARLDARYRQPLDVPDQEDSP
>Mature_211_residues
TTPVRIIGVTGGIASGKSTVAAMFAEHGIPWVDADHVARDVVAPGEPALAEIVARYGPSLVDDRGHLQRRVLRDIVFADD
EERRWLESVTHPRIRQRLCDTLDTMRHGDAPYGLLVSPLLFETDQASLVDRCLVIDVPEKVQVARVRARDTVSESQAHAI
LAAQMPRQARLARADDVIENDGDLASLKAQVARLDARYRQPLDVPDQEDSP

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=202, Percent_Identity=35.1485148514851, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI191252795, Length=202, Percent_Identity=35.1485148514851, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI110227607, Length=169, Percent_Identity=28.4023668639053, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI110227605, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227603, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI110227601, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI205277394, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786292, Length=195, Percent_Identity=45.6410256410256, Blast_Score=155, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=33.5, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320402, Length=191, Percent_Identity=34.0314136125654, Blast_Score=108, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24644728, Length=180, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658602, Length=200, Percent_Identity=30.5, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23396; Mature: 23265

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPVRIIGVTGGIASGKSTVAAMFAEHGIPWVDADHVARDVVAPGEPALAEIVARYGPS
CCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
LVDDRGHLQRRVLRDIVFADDEERRWLESVTHPRIRQRLCDTLDTMRHGDAPYGLLVSPL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LFETDQASLVDRCLVIDVPEKVQVARVRARDTVSESQAHAILAAQMPRQARLARADDVIE
HHCCCHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NDGDLASLKAQVARLDARYRQPLDVPDQEDSP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTPVRIIGVTGGIASGKSTVAAMFAEHGIPWVDADHVARDVVAPGEPALAEIVARYGPS
CCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCC
LVDDRGHLQRRVLRDIVFADDEERRWLESVTHPRIRQRLCDTLDTMRHGDAPYGLLVSPL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LFETDQASLVDRCLVIDVPEKVQVARVRARDTVSESQAHAILAAQMPRQARLARADDVIE
HHCCCHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
NDGDLASLKAQVARLDARYRQPLDVPDQEDSP
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA