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The map label for this gene is pilC [H]

Identifier: 92114297

GI number: 92114297

Start: 2448830

End: 2450062

Strand: Direct

Name: pilC [H]

Synonym: Csal_2175

Alternate gene names: 92114297

Gene position: 2448830-2450062 (Clockwise)

Preceding gene: 92114296

Following gene: 92114298

Centisome position: 66.24

GC content: 65.04

Gene sequence:

>1233_bases
ATGGCGGTAGCGACACGTAGCAAGGCGCCACGGCGCGTCGTCCTGCATCGCTGGCGATGGAAGGGCAAGAATTCCCGTGG
CGAGACCATCCAGGGCGAGCTGGTGGCGGCAGATGAAATGACGGTGCGCCAGGAGCTCGGCCGCCAGAACATTCTGGTCA
AGCGCATCCAGCGCGTGCGCAGCCCCTTCGGCATCGGCCGCATACGCCCCCAGGACATCACCCTGTTCGCACGGCAGATG
GCGACGATGATCCGTGCCGGCATCCCGCTGCTGCAAGCCTTCAGCGTGGTGTCGGAGAGTCTCAAGCGCCCCGCCATGCA
CCACCTCATCGAGACCTTGATGAACGAAGTCTCGGCGGGGGCCAGCTTCTCCGAGGCGCTGGCCCAGCATCCGCAGCATT
TCGATCGCATGTTCGTCAACATGGTCGAGGCCGGCGAGCAGTCGGGATCGCTGGATCGCATGCTGGAGCGGGTGGCGAGC
TACAAGGAAAAGATCGACTCCCTGCGCGCGCGCGTGCGCAAGGCCCTCTATTACCCCGCCGCCGTGGTCCTGGTGGGCAT
GGGGGTCACCGCCTTGCTGCTGGTCAAGGTCGTACCTCAGTTCGAGAGCCTGTTTCGCGGCTTCGGCGCCGACTTGCCCG
CCTTCACGCAGTTGACCATTGCGCTGTCGCAGTGGGTCCAGGCGTACTGGCCGCACCTGCTCGGCGCCTTCATCGCTGCC
TTGCTGCTGGTCCGTCTCGGCATCCGTCGCTCGCCGGGCTTCGCCTACCGTGCCGATGCGCTCATGCTGCGCCTGCCGGT
CATCGGCGACATTCTGGACAAATCGTCGGTGGCGCGCTTTTCGCGCACCCTGGCGACGACCTTCAGCGCCGGGGTGCCAC
TGGTCGAATCGCTCAACACCGCAGCCGGCTCCACCGGCAATCGGGTCTACCAACGCGCCATCGGCGAGGTCCGCGAGCAT
GTCGCCAGCGGCCAGCAGCTCAACTTCGCCATGCGTGCCACCGGGCGCTTCCCCAACCTGGCGGTGCAGATGATTGGCGT
GGGCGAAGAATCCGGTGCGCTGGACGCCATGCTCAACAAGGTGGCGGATTTCTACGAGGAAGACGTCGATACCAAGGTCG
ACGCGCTGACATCGCTGCTCGAACCCTTCATCATCGTGGTGCTGGGCGTACTGGTCGGCGGCCTCGTCGTCTCGATGTAT
CTGCCGATCTTCGAAATGGGCTCGGCCATTTGA

Upstream 100 bases:

>100_bases
GCGGACTGAGCAAGGTGCTCGCCGGCATCACCAGCCTCGAGGAAATCAACCGCGTGGTGCTGGAATGAAAGCTCAGGGCA
AGTGACAAGAGGGGAACGAC

Downstream 100 bases:

>100_bases
GCCGGCCGCACGCGTCGCGCTCGCCCGCGCCGGCGTGACACCGGCCCGTTCGCGCCCACTTCTGCCTGTCCATCCCGAAG
GCAGGCATTTTCAGACATAG

Product: type II secretion system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAVATRSKAPRRVVLHRWRWKGKNSRGETIQGELVAADEMTVRQELGRQNILVKRIQRVRSPFGIGRIRPQDITLFARQM
ATMIRAGIPLLQAFSVVSESLKRPAMHHLIETLMNEVSAGASFSEALAQHPQHFDRMFVNMVEAGEQSGSLDRMLERVAS
YKEKIDSLRARVRKALYYPAAVVLVGMGVTALLLVKVVPQFESLFRGFGADLPAFTQLTIALSQWVQAYWPHLLGAFIAA
LLLVRLGIRRSPGFAYRADALMLRLPVIGDILDKSSVARFSRTLATTFSAGVPLVESLNTAAGSTGNRVYQRAIGEVREH
VASGQQLNFAMRATGRFPNLAVQMIGVGEESGALDAMLNKVADFYEEDVDTKVDALTSLLEPFIIVVLGVLVGGLVVSMY
LPIFEMGSAI

Sequences:

>Translated_410_residues
MAVATRSKAPRRVVLHRWRWKGKNSRGETIQGELVAADEMTVRQELGRQNILVKRIQRVRSPFGIGRIRPQDITLFARQM
ATMIRAGIPLLQAFSVVSESLKRPAMHHLIETLMNEVSAGASFSEALAQHPQHFDRMFVNMVEAGEQSGSLDRMLERVAS
YKEKIDSLRARVRKALYYPAAVVLVGMGVTALLLVKVVPQFESLFRGFGADLPAFTQLTIALSQWVQAYWPHLLGAFIAA
LLLVRLGIRRSPGFAYRADALMLRLPVIGDILDKSSVARFSRTLATTFSAGVPLVESLNTAAGSTGNRVYQRAIGEVREH
VASGQQLNFAMRATGRFPNLAVQMIGVGEESGALDAMLNKVADFYEEDVDTKVDALTSLLEPFIIVVLGVLVGGLVVSMY
LPIFEMGSAI
>Mature_409_residues
AVATRSKAPRRVVLHRWRWKGKNSRGETIQGELVAADEMTVRQELGRQNILVKRIQRVRSPFGIGRIRPQDITLFARQMA
TMIRAGIPLLQAFSVVSESLKRPAMHHLIETLMNEVSAGASFSEALAQHPQHFDRMFVNMVEAGEQSGSLDRMLERVASY
KEKIDSLRARVRKALYYPAAVVLVGMGVTALLLVKVVPQFESLFRGFGADLPAFTQLTIALSQWVQAYWPHLLGAFIAAL
LLVRLGIRRSPGFAYRADALMLRLPVIGDILDKSSVARFSRTLATTFSAGVPLVESLNTAAGSTGNRVYQRAIGEVREHV
ASGQQLNFAMRATGRFPNLAVQMIGVGEESGALDAMLNKVADFYEEDVDTKVDALTSLLEPFIIVVLGVLVGGLVVSMYL
PIFEMGSAI

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=401, Percent_Identity=29.1770573566085, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786295, Length=393, Percent_Identity=27.2264631043257, Blast_Score=166, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 45135; Mature: 45004

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVATRSKAPRRVVLHRWRWKGKNSRGETIQGELVAADEMTVRQELGRQNILVKRIQRVR
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHH
SPFGIGRIRPQDITLFARQMATMIRAGIPLLQAFSVVSESLKRPAMHHLIETLMNEVSAG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
ASFSEALAQHPQHFDRMFVNMVEAGEQSGSLDRMLERVASYKEKIDSLRARVRKALYYPA
CCHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVLVGMGVTALLLVKVVPQFESLFRGFGADLPAFTQLTIALSQWVQAYWPHLLGAFIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVRLGIRRSPGFAYRADALMLRLPVIGDILDKSSVARFSRTLATTFSAGVPLVESLNT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGSTGNRVYQRAIGEVREHVASGQQLNFAMRATGRFPNLAVQMIGVGEESGALDAMLNK
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHEEECCCCCCHHHHHHHH
VADFYEEDVDTKVDALTSLLEPFIIVVLGVLVGGLVVSMYLPIFEMGSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVATRSKAPRRVVLHRWRWKGKNSRGETIQGELVAADEMTVRQELGRQNILVKRIQRVR
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHHHHHH
SPFGIGRIRPQDITLFARQMATMIRAGIPLLQAFSVVSESLKRPAMHHLIETLMNEVSAG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
ASFSEALAQHPQHFDRMFVNMVEAGEQSGSLDRMLERVASYKEKIDSLRARVRKALYYPA
CCHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVVLVGMGVTALLLVKVVPQFESLFRGFGADLPAFTQLTIALSQWVQAYWPHLLGAFIAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLVRLGIRRSPGFAYRADALMLRLPVIGDILDKSSVARFSRTLATTFSAGVPLVESLNT
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AAGSTGNRVYQRAIGEVREHVASGQQLNFAMRATGRFPNLAVQMIGVGEESGALDAMLNK
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHEEECCCCCCHHHHHHHH
VADFYEEDVDTKVDALTSLLEPFIIVVLGVLVGGLVVSMYLPIFEMGSAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]