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The map label for this gene is panE [H]

Identifier: 92114269

GI number: 92114269

Start: 2419333

End: 2420244

Strand: Direct

Name: panE [H]

Synonym: Csal_2147

Alternate gene names: 92114269

Gene position: 2419333-2420244 (Clockwise)

Preceding gene: 92114268

Following gene: 92114270

Centisome position: 65.45

GC content: 68.31

Gene sequence:

>912_bases
ATGCCCGCCTCGTCTCCTTGGTGGCTGCTCGGTGCCGGCGCCATGGGACGCCTGTTCGCCGCCCGCCTGAGCGTCGCGCG
TCCGGTGTGCCTGATCGGCCGCCGCGACGCCCCGAACGTGCTGCATTATCGCGACCCAAGCGGCGTCGATCACGCCTTGG
ACGTGCCCTGCTGCACACTGACGTCACTGGCGGTATCGGATCCGACACCACCGGGCCTGGTCGTGCTCGCCACCAAGAGC
CATGACACCCAGACCGCCCTGGACGCGTTGAGCGCGCATGTCGACGCCCGGACGCCATTGCTGCTGTTGCAGAACGGCTT
CCGCGTCCAGCCGATCGTCACGCGTCAGTGGCTGGGTCCCGTGCTCTGTGCCAGCACCACCGAGGGGGCCTATGTCGAAT
CCGCACCCGACGGCGGAACGTGCGTCGTCCATGCCGGAACGGGCGTCACCTGGATCGGCGACCTCGACCACGCCTGGCCC
GACCTGGCGCATGGCGTCGTCGAGGCACTCACGGCAGCGGGGATGAGGGCGCAGGTCGATGACGACATCGCGCAGCGCCT
GTGGCACAAGCTGGCCGTCAATGCCGCCATCAATCCTCTCGTGGCACGCCACCGAATTCGCAACGGCCAGTTGCGCGATC
GGCCGTTTCGACGCATGGTCGACGCACTCATCGACGAAATCGGGCCGCTGATCGAAGGTCAGGGTGTCGAGCCTCCCGCG
GCCGGCTGGTCGGCACTGATCTGGCAAGTCATCGAGGCCACGGCCGACAATCGCGCCTCGATGCTGCAAGATGTGCTTGC
CGGCCGCCCCACCGAACGTGAAGCGATACTCGGCCCGCTGCGGGACGCGGCCCGGCGCCAGCAGCGTTCGACCCCGTCCC
TGGATGCGCTGTATCGCGACACGCCTTCGTGA

Upstream 100 bases:

>100_bases
GCACCCGGCGCGGCAGCGGCGACGCCTCGTCCAGCCCCCGACGCCGCGCCGGGAAGTCCACGGCCAGGCGTCGCACCTCC
TCCAAGAAAGGCCAGACATG

Downstream 100 bases:

>100_bases
TGGCGACGCAACTGGCACGGGGCAGGCCCAAGGTAACCATCATCCTCAAGGAGACGTCATGCGCCACCGCCTCTTCATCA
CGTTACTGCTGGCATTCCTG

Product: 2-dehydropantoate 2-reductase

Products: NA

Alternate protein names: Ketopantoate reductase; KPA reductase; KPR [H]

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPASSPWWLLGAGAMGRLFAARLSVARPVCLIGRRDAPNVLHYRDPSGVDHALDVPCCTLTSLAVSDPTPPGLVVLATKS
HDTQTALDALSAHVDARTPLLLLQNGFRVQPIVTRQWLGPVLCASTTEGAYVESAPDGGTCVVHAGTGVTWIGDLDHAWP
DLAHGVVEALTAAGMRAQVDDDIAQRLWHKLAVNAAINPLVARHRIRNGQLRDRPFRRMVDALIDEIGPLIEGQGVEPPA
AGWSALIWQVIEATADNRASMLQDVLAGRPTEREAILGPLRDAARRQQRSTPSLDALYRDTPS

Sequences:

>Translated_303_residues
MPASSPWWLLGAGAMGRLFAARLSVARPVCLIGRRDAPNVLHYRDPSGVDHALDVPCCTLTSLAVSDPTPPGLVVLATKS
HDTQTALDALSAHVDARTPLLLLQNGFRVQPIVTRQWLGPVLCASTTEGAYVESAPDGGTCVVHAGTGVTWIGDLDHAWP
DLAHGVVEALTAAGMRAQVDDDIAQRLWHKLAVNAAINPLVARHRIRNGQLRDRPFRRMVDALIDEIGPLIEGQGVEPPA
AGWSALIWQVIEATADNRASMLQDVLAGRPTEREAILGPLRDAARRQQRSTPSLDALYRDTPS
>Mature_302_residues
PASSPWWLLGAGAMGRLFAARLSVARPVCLIGRRDAPNVLHYRDPSGVDHALDVPCCTLTSLAVSDPTPPGLVVLATKSH
DTQTALDALSAHVDARTPLLLLQNGFRVQPIVTRQWLGPVLCASTTEGAYVESAPDGGTCVVHAGTGVTWIGDLDHAWPD
LAHGVVEALTAAGMRAQVDDDIAQRLWHKLAVNAAINPLVARHRIRNGQLRDRPFRRMVDALIDEIGPLIEGQGVEPPAA
GWSALIWQVIEATADNRASMLQDVLAGRPTEREAILGPLRDAARRQQRSTPSLDALYRDTPS

Specific function: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid [H]

COG id: COG1893

COG function: function code H; Ketopantoate reductase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketopantoate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786627, Length=303, Percent_Identity=28.3828382838284, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR003710
- InterPro:   IPR013752
- InterPro:   IPR013332
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02558 ApbA; PF08546 ApbA_C [H]

EC number: =1.1.1.169 [H]

Molecular weight: Translated: 32576; Mature: 32445

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASSPWWLLGAGAMGRLFAARLSVARPVCLIGRRDAPNVLHYRDPSGVDHALDVPCCTL
CCCCCCCEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCCCCCCHHHH
TSLAVSDPTPPGLVVLATKSHDTQTALDALSAHVDARTPLLLLQNGFRVQPIVTRQWLGP
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCEECEEHHHHHHCH
VLCASTTEGAYVESAPDGGTCVVHAGTGVTWIGDLDHAWPDLAHGVVEALTAAGMRAQVD
HHCCCCCCCCEEECCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
DDIAQRLWHKLAVNAAINPLVARHRIRNGQLRDRPFRRMVDALIDEIGPLIEGQGVEPPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
AGWSALIWQVIEATADNRASMLQDVLAGRPTEREAILGPLRDAARRQQRSTPSLDALYRD
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCC
TPS
CCC
>Mature Secondary Structure 
PASSPWWLLGAGAMGRLFAARLSVARPVCLIGRRDAPNVLHYRDPSGVDHALDVPCCTL
CCCCCCEEEECCHHHHHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCCCCCCHHHH
TSLAVSDPTPPGLVVLATKSHDTQTALDALSAHVDARTPLLLLQNGFRVQPIVTRQWLGP
HHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCEECEEHHHHHHCH
VLCASTTEGAYVESAPDGGTCVVHAGTGVTWIGDLDHAWPDLAHGVVEALTAAGMRAQVD
HHCCCCCCCCEEECCCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCC
DDIAQRLWHKLAVNAAINPLVARHRIRNGQLRDRPFRRMVDALIDEIGPLIEGQGVEPPA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
AGWSALIWQVIEATADNRASMLQDVLAGRPTEREAILGPLRDAARRQQRSTPSLDALYRD
CHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHCC
TPS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]