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The map label for this gene is yhcK [H]

Identifier: 92114132

GI number: 92114132

Start: 2270477

End: 2272201

Strand: Direct

Name: yhcK [H]

Synonym: Csal_2010

Alternate gene names: 92114132

Gene position: 2270477-2272201 (Clockwise)

Preceding gene: 92114131

Following gene: 92114156

Centisome position: 61.42

GC content: 64.35

Gene sequence:

>1725_bases
ATGTGCCGCTCACGGATGCCGGAAGCCGAAGCCCAGGAAGCCGAGCGCGTCGCCGCGCTGCATCGGCTGGGCATCTACGA
AACGTCCTGCGATCCGGAGCTGAACCGGCTCATGACCATGATCGGGGAACTCTTCGACGTTCCCTGCGCCATGATCAATC
TCGTCGACCGGGAACGGACCTGGTGCCTGGCGAGTTCCAGCGACCTCGCCGCGCCGCCGCGTCGCGAGGATTCGCTCTGT
GCCTTCACGGTGGATCATGATACGGCGTTGTTCATCGAGGACATGCGCGATGCCGATGGATTTCGCGAACACCCGCTGGT
GAGGGACACGCCTTTCATCCGCGCCTTCGCCGGCGAAAGAATCCTGTCGTTGAGCGGCCATCTGCTGGGCACGCTGTGCC
TGGTCGATATCCGCCCACGGGTTTTCGACGCCGAGAGCCGGCAACGCCTGGCCGACCTGGCCAAGCTCGTCTCGCTGCGC
CTCAACCAGCGCCTGATCGACGAGCAGCGCCATACCGCCGATGCGATGATCGATCAGCAGACCCAGCTGCTCGACCATCT
ACCGGACGGGATCGTGCTGCTCGACGACCGCCGCGTCGTGCATTACGCCAACGCCGCCGCCCAGCGCCTGCTGGGCGGCG
CCTCTCATGACGTCAAGGGCTGTGCCTTCGACACCCTCGTCGCACAGCCCGAAGGGCACGATTTCGCCACGGCGTCACGC
ACCGGCTCGCCACTCGAGATCCATGCACTGCCCAGGTTCCAGGGGTTCGAGGCCTTGCAGCTGGGCGACCGCGCCTCGCT
CGTGGGCACGCACCAAGCCCTGCAACGCTTGCGCAGTCTGGTGGATGCCTGGCCCGATGGCGTACTGATCTGCGATTACG
ACAACCTGCGCATCGTCGAGTGGAACATCGCCGCACGCCGTTTGCTAGGCACGCAGGCATCATCGCTCGAAGGCACTCGT
CTTCCCCAGTGGTTCCTGTCGGGCGACCGGCGCACGCTGCAGCGGCGCATCCGTGCGGAGCTCGGTGAAGGGGATGGCAC
CCTGCGCCATAACGCCACCTTGCACAACGACACTCCGGTCGAAGTCACGCTGGTGCCGATGCAGGACGCCAGCGAGACAT
CGTTGATCGTCGTCCTGCGCGACCGCAGTCCTTATCTTCAGCACCTGCGCACGGTCACGCGCAAGCTTGCCAAGGCCGAG
GAAATGATCAGCCAGGATGCCCTGACCGGCCTGCTCAACCGCTTCGGTTTCAAGCAGGCCATCGACGAGTTCATGGTCGA
GGCCGAGCGCGGCGTCCCCTTCGCGCTGCTCATCGCCGATATCGATCATTTCAAGGATATCAACGATACCTATGGCCACC
AGCTAGGCGACGAGGCGCTCAAGATCGTCGCCAGCCGGCTTGCCGAGCAGCTTCGTGATGGCGATGCCGTGGCACGTTAT
GGCGGCGAGGAATTCTGCATGCTGATGACGGTTCCCGAGGACCGGGTCGTGGAAGTGGCCGAGCGAATCCGGCGGACCGT
CGCCGCCACGCCCGTGACACTCGATGACGGCAAGGAACTCGCGCTCACGATTAGTATCGGCGCGACGTACCATACCCCCG
GCCTGGACGAGGACAGCATGTTCGAACGCGCCGACGAAGCGCTCTATGAAGCCAAGGAGTACGGACGCAACCGTACCGTC
ATGCTAAACGCCGCAACGCCCAGGGCGCGTGACGAAGAAGAGTGA

Upstream 100 bases:

>100_bases
ATAAGCAGGGTATCGTTTATAGCGGGATGATCCTTGTACTCATCCCGCCAGGCCCCCATTATCCCATCCGCCATGTTCCA
ACCACGAGACATTTCCCCTC

Downstream 100 bases:

>100_bases
CGACGAAAGGGTGACGACAGCCAGCGCCTTGCGGTAGAAAAGCTCCGGCGCCGAATCGGTGACCCGGAGGCGATGCCACT
AGGCCGCCAGCCGGGCACGC

Product: PAS/PAC and GAF sensor-containing diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MCRSRMPEAEAQEAERVAALHRLGIYETSCDPELNRLMTMIGELFDVPCAMINLVDRERTWCLASSSDLAAPPRREDSLC
AFTVDHDTALFIEDMRDADGFREHPLVRDTPFIRAFAGERILSLSGHLLGTLCLVDIRPRVFDAESRQRLADLAKLVSLR
LNQRLIDEQRHTADAMIDQQTQLLDHLPDGIVLLDDRRVVHYANAAAQRLLGGASHDVKGCAFDTLVAQPEGHDFATASR
TGSPLEIHALPRFQGFEALQLGDRASLVGTHQALQRLRSLVDAWPDGVLICDYDNLRIVEWNIAARRLLGTQASSLEGTR
LPQWFLSGDRRTLQRRIRAELGEGDGTLRHNATLHNDTPVEVTLVPMQDASETSLIVVLRDRSPYLQHLRTVTRKLAKAE
EMISQDALTGLLNRFGFKQAIDEFMVEAERGVPFALLIADIDHFKDINDTYGHQLGDEALKIVASRLAEQLRDGDAVARY
GGEEFCMLMTVPEDRVVEVAERIRRTVAATPVTLDDGKELALTISIGATYHTPGLDEDSMFERADEALYEAKEYGRNRTV
MLNAATPRARDEEE

Sequences:

>Translated_574_residues
MCRSRMPEAEAQEAERVAALHRLGIYETSCDPELNRLMTMIGELFDVPCAMINLVDRERTWCLASSSDLAAPPRREDSLC
AFTVDHDTALFIEDMRDADGFREHPLVRDTPFIRAFAGERILSLSGHLLGTLCLVDIRPRVFDAESRQRLADLAKLVSLR
LNQRLIDEQRHTADAMIDQQTQLLDHLPDGIVLLDDRRVVHYANAAAQRLLGGASHDVKGCAFDTLVAQPEGHDFATASR
TGSPLEIHALPRFQGFEALQLGDRASLVGTHQALQRLRSLVDAWPDGVLICDYDNLRIVEWNIAARRLLGTQASSLEGTR
LPQWFLSGDRRTLQRRIRAELGEGDGTLRHNATLHNDTPVEVTLVPMQDASETSLIVVLRDRSPYLQHLRTVTRKLAKAE
EMISQDALTGLLNRFGFKQAIDEFMVEAERGVPFALLIADIDHFKDINDTYGHQLGDEALKIVASRLAEQLRDGDAVARY
GGEEFCMLMTVPEDRVVEVAERIRRTVAATPVTLDDGKELALTISIGATYHTPGLDEDSMFERADEALYEAKEYGRNRTV
MLNAATPRARDEEE
>Mature_574_residues
MCRSRMPEAEAQEAERVAALHRLGIYETSCDPELNRLMTMIGELFDVPCAMINLVDRERTWCLASSSDLAAPPRREDSLC
AFTVDHDTALFIEDMRDADGFREHPLVRDTPFIRAFAGERILSLSGHLLGTLCLVDIRPRVFDAESRQRLADLAKLVSLR
LNQRLIDEQRHTADAMIDQQTQLLDHLPDGIVLLDDRRVVHYANAAAQRLLGGASHDVKGCAFDTLVAQPEGHDFATASR
TGSPLEIHALPRFQGFEALQLGDRASLVGTHQALQRLRSLVDAWPDGVLICDYDNLRIVEWNIAARRLLGTQASSLEGTR
LPQWFLSGDRRTLQRRIRAELGEGDGTLRHNATLHNDTPVEVTLVPMQDASETSLIVVLRDRSPYLQHLRTVTRKLAKAE
EMISQDALTGLLNRFGFKQAIDEFMVEAERGVPFALLIADIDHFKDINDTYGHQLGDEALKIVASRLAEQLRDGDAVARY
GGEEFCMLMTVPEDRVVEVAERIRRTVAATPVTLDDGKELALTISIGATYHTPGLDEDSMFERADEALYEAKEYGRNRTV
MLNAATPRARDEEE

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=179, Percent_Identity=39.1061452513966, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1787262, Length=233, Percent_Identity=31.7596566523605, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI87081881, Length=163, Percent_Identity=40.4907975460123, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=34.5454545454545, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1787816, Length=191, Percent_Identity=33.5078534031414, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787802, Length=162, Percent_Identity=38.8888888888889, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=35.2201257861635, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788956, Length=151, Percent_Identity=34.4370860927152, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI87081921, Length=438, Percent_Identity=23.2876712328767, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=179, Percent_Identity=29.608938547486, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=162, Percent_Identity=28.3950617283951, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787541, Length=159, Percent_Identity=32.0754716981132, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788381, Length=225, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 64250; Mature: 64250

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50112 PAS ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRSRMPEAEAQEAERVAALHRLGIYETSCDPELNRLMTMIGELFDVPCAMINLVDRERT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCE
WCLASSSDLAAPPRREDSLCAFTVDHDTALFIEDMRDADGFREHPLVRDTPFIRAFAGER
EEEECCCCCCCCCCCCCCEEEEEECCCCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHCCH
ILSLSGHLLGTLCLVDIRPRVFDAESRQRLADLAKLVSLRLNQRLIDEQRHTADAMIDQQ
HHHHHHHHHHHHHHEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLLDHLPDGIVLLDDRRVVHYANAAAQRLLGGASHDVKGCAFDTLVAQPEGHDFATASR
HHHHHHCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
TGSPLEIHALPRFQGFEALQLGDRASLVGTHQALQRLRSLVDAWPDGVLICDYDNLRIVE
CCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEE
WNIAARRLLGTQASSLEGTRLPQWFLSGDRRTLQRRIRAELGEGDGTLRHNATLHNDTPV
ECHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEECCEECCCCCE
EVTLVPMQDASETSLIVVLRDRSPYLQHLRTVTRKLAKAEEMISQDALTGLLNRFGFKQA
EEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
IDEFMVEAERGVPFALLIADIDHFKDINDTYGHQLGDEALKIVASRLAEQLRDGDAVARY
HHHHHHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GGEEFCMLMTVPEDRVVEVAERIRRTVAATPVTLDDGKELALTISIGATYHTPGLDEDSM
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEEECCEECCCCCCHHHH
FERADEALYEAKEYGRNRTVMLNAATPRARDEEE
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure
MCRSRMPEAEAQEAERVAALHRLGIYETSCDPELNRLMTMIGELFDVPCAMINLVDRERT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCE
WCLASSSDLAAPPRREDSLCAFTVDHDTALFIEDMRDADGFREHPLVRDTPFIRAFAGER
EEEECCCCCCCCCCCCCCEEEEEECCCCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHCCH
ILSLSGHLLGTLCLVDIRPRVFDAESRQRLADLAKLVSLRLNQRLIDEQRHTADAMIDQQ
HHHHHHHHHHHHHHEECCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQLLDHLPDGIVLLDDRRVVHYANAAAQRLLGGASHDVKGCAFDTLVAQPEGHDFATASR
HHHHHHCCCCEEEECCCCEEEHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCCCCC
TGSPLEIHALPRFQGFEALQLGDRASLVGTHQALQRLRSLVDAWPDGVLICDYDNLRIVE
CCCCEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEE
WNIAARRLLGTQASSLEGTRLPQWFLSGDRRTLQRRIRAELGEGDGTLRHNATLHNDTPV
ECHHHHHHHCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCEEECCEECCCCCE
EVTLVPMQDASETSLIVVLRDRSPYLQHLRTVTRKLAKAEEMISQDALTGLLNRFGFKQA
EEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
IDEFMVEAERGVPFALLIADIDHFKDINDTYGHQLGDEALKIVASRLAEQLRDGDAVARY
HHHHHHHHHCCCCEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHC
GGEEFCMLMTVPEDRVVEVAERIRRTVAATPVTLDDGKELALTISIGATYHTPGLDEDSM
CCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEECCCCEEEEEEEECCEECCCCCCHHHH
FERADEALYEAKEYGRNRTVMLNAATPRARDEEE
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]