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The map label for this gene is lolC [H]

Identifier: 92113706

GI number: 92113706

Start: 1801167

End: 1802408

Strand: Direct

Name: lolC [H]

Synonym: Csal_1582

Alternate gene names: 92113706

Gene position: 1801167-1802408 (Clockwise)

Preceding gene: 92113702

Following gene: 92113707

Centisome position: 48.72

GC content: 62.0

Gene sequence:

>1242_bases
ATGCTGGATCGCTTGCCGTTTCTTATCGGACTGCGCTACGTGCGCGCCAAACGTCGCAACCATTTTATTTCCTTCATTTC
CCTCACTTCCATGCTCGGCCTGATGCTGGGGGTGGCGGTGCTGATTCTCGTGCTGTCGGTGATGAATGGTTTCGATCATG
AACTGCGGACGCGGGTACTGGGCATGGTGCCGCATACCCGCATCGAAGCCCAGGGGGGCATGACGGACTGGAAGGCGCTC
GCCGAACGCCTCGAGAAGCGTGATTACGTCATCGGTGCGGCCCCGTTCGTGCAACAGCAGGGGATGTTTTCCTCCGAGGG
GCGCACGCAAGGCGCGATGGTCAACGGGATTCAACCGGACTATGAAAGCAAGGTCTCGATCATCGACGAGCACATGACGC
GTGGCTCGCTGGATGATCTGGCGCCCGGGGAGTGGCACGTGGTGCTGGGGGATCTGCTGGCGCGCAATCTCGGCGTGGGG
GTCGGGGATCGCGTGACGCTGCTGGTGCCCGAGGCCTCGATCACACCGGGAGGCGTGTTCCCGCGGCTCAAGCGCTTCAC
CGTCAGCGGCATCTTCAAGGTGGGGGCCGACCTGGACGCCAACCTTGCCTATGCCAACATCCAGGACATGCAGACGCTGG
GACGCCTGGGCGACTCGGTGGAAGGCCTGCGTCTGGAACTGGACGACCTGTTTCAGGCAGGGCCGGTCACGCGCGCGATC
GTGAACGACCTGGGGAGCGGCTATCGGGGGGTGGACTGGACCTACACCCACGGCAATCTCTTCCAGGCCATCCAGATGGA
AAAGCGCATGATCGGCCTGCTGCTGATGGTGATCGTCGCCGTGGCGGCATTCAATATCGTCTCCACGCTGGTCATGGTGG
TGACCGACAAGCATGCCGACATCGCCATCCTGCGGACCATCGGCGCCAAGCCGGGGACCATCATGCGCATCTTCATGGTG
CAAGGCATGGCGATCGGCATCATCGGCATCGTCGTGGGGGTGTTGCTCGGCGTGGTGCTGGCACTGTCCGTGTCGGATCT
GATCGCCTGGTTCGAGGCGTTGACCGGTATCCACTTCCTGGACCCGAATGTCTATTTCATCAGCTACCTGCCCTCGCAAC
TTCAGTGGAGCGATGTGGGCATCATCGTGGGATCGGCCTTCGTGCTGACATTCCTGTCAACGCTGTATCCCGCCTGGCGG
GCGGCGCGTATTCAACCGGCCGAGGTATTGCGCTATGAGTGA

Upstream 100 bases:

>100_bases
AGGACCCACGGGCGGCCGATGCGGCGCCCTTCGATGGCTCATGCAGGAACGCGCAAAAACACGTACCATGAGCCCGGCTC
ATACCAAGGAATCGATGTCG

Downstream 100 bases:

>100_bases
GGACACCGCGATGGCATCGAACGACACCCCGGCGTTCGCCAACAACGAGATCATGCTGAAGTGCGAGGGCCTGACGCGCA
TTTATCGCGAAGGCCCGCAG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MLDRLPFLIGLRYVRAKRRNHFISFISLTSMLGLMLGVAVLILVLSVMNGFDHELRTRVLGMVPHTRIEAQGGMTDWKAL
AERLEKRDYVIGAAPFVQQQGMFSSEGRTQGAMVNGIQPDYESKVSIIDEHMTRGSLDDLAPGEWHVVLGDLLARNLGVG
VGDRVTLLVPEASITPGGVFPRLKRFTVSGIFKVGADLDANLAYANIQDMQTLGRLGDSVEGLRLELDDLFQAGPVTRAI
VNDLGSGYRGVDWTYTHGNLFQAIQMEKRMIGLLLMVIVAVAAFNIVSTLVMVVTDKHADIAILRTIGAKPGTIMRIFMV
QGMAIGIIGIVVGVLLGVVLALSVSDLIAWFEALTGIHFLDPNVYFISYLPSQLQWSDVGIIVGSAFVLTFLSTLYPAWR
AARIQPAEVLRYE

Sequences:

>Translated_413_residues
MLDRLPFLIGLRYVRAKRRNHFISFISLTSMLGLMLGVAVLILVLSVMNGFDHELRTRVLGMVPHTRIEAQGGMTDWKAL
AERLEKRDYVIGAAPFVQQQGMFSSEGRTQGAMVNGIQPDYESKVSIIDEHMTRGSLDDLAPGEWHVVLGDLLARNLGVG
VGDRVTLLVPEASITPGGVFPRLKRFTVSGIFKVGADLDANLAYANIQDMQTLGRLGDSVEGLRLELDDLFQAGPVTRAI
VNDLGSGYRGVDWTYTHGNLFQAIQMEKRMIGLLLMVIVAVAAFNIVSTLVMVVTDKHADIAILRTIGAKPGTIMRIFMV
QGMAIGIIGIVVGVLLGVVLALSVSDLIAWFEALTGIHFLDPNVYFISYLPSQLQWSDVGIIVGSAFVLTFLSTLYPAWR
AARIQPAEVLRYE
>Mature_413_residues
MLDRLPFLIGLRYVRAKRRNHFISFISLTSMLGLMLGVAVLILVLSVMNGFDHELRTRVLGMVPHTRIEAQGGMTDWKAL
AERLEKRDYVIGAAPFVQQQGMFSSEGRTQGAMVNGIQPDYESKVSIIDEHMTRGSLDDLAPGEWHVVLGDLLARNLGVG
VGDRVTLLVPEASITPGGVFPRLKRFTVSGIFKVGADLDANLAYANIQDMQTLGRLGDSVEGLRLELDDLFQAGPVTRAI
VNDLGSGYRGVDWTYTHGNLFQAIQMEKRMIGLLLMVIVAVAAFNIVSTLVMVVTDKHADIAILRTIGAKPGTIMRIFMV
QGMAIGIIGIVVGVLLGVVLALSVSDLIAWFEALTGIHFLDPNVYFISYLPSQLQWSDVGIIVGSAFVLTFLSTLYPAWR
AARIQPAEVLRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=407, Percent_Identity=37.5921375921376, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787360, Length=415, Percent_Identity=37.5903614457831, Blast_Score=227, Evalue=9e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45269; Mature: 45269

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDRLPFLIGLRYVRAKRRNHFISFISLTSMLGLMLGVAVLILVLSVMNGFDHELRTRVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPHTRIEAQGGMTDWKALAERLEKRDYVIGAAPFVQQQGMFSSEGRTQGAMVNGIQPD
HCCCCCEEECCCCCCHHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCCCCEECCCCCC
YESKVSIIDEHMTRGSLDDLAPGEWHVVLGDLLARNLGVGVGDRVTLLVPEASITPGGVF
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
PRLKRFTVSGIFKVGADLDANLAYANIQDMQTLGRLGDSVEGLRLELDDLFQAGPVTRAI
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCHHEEEHHHHHCCCCHHHHH
VNDLGSGYRGVDWTYTHGNLFQAIQMEKRMIGLLLMVIVAVAAFNIVSTLVMVVTDKHAD
HHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAILRTIGAKPGTIMRIFMVQGMAIGIIGIVVGVLLGVVLALSVSDLIAWFEALTGIHFL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DPNVYFISYLPSQLQWSDVGIIVGSAFVLTFLSTLYPAWRAARIQPAEVLRYE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure
MLDRLPFLIGLRYVRAKRRNHFISFISLTSMLGLMLGVAVLILVLSVMNGFDHELRTRVL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GMVPHTRIEAQGGMTDWKALAERLEKRDYVIGAAPFVQQQGMFSSEGRTQGAMVNGIQPD
HCCCCCEEECCCCCCHHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCCCCEECCCCCC
YESKVSIIDEHMTRGSLDDLAPGEWHVVLGDLLARNLGVGVGDRVTLLVPEASITPGGVF
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCC
PRLKRFTVSGIFKVGADLDANLAYANIQDMQTLGRLGDSVEGLRLELDDLFQAGPVTRAI
HHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCCCHHEEEHHHHHCCCCHHHHH
VNDLGSGYRGVDWTYTHGNLFQAIQMEKRMIGLLLMVIVAVAAFNIVSTLVMVVTDKHAD
HHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IAILRTIGAKPGTIMRIFMVQGMAIGIIGIVVGVLLGVVLALSVSDLIAWFEALTGIHFL
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
DPNVYFISYLPSQLQWSDVGIIVGSAFVLTFLSTLYPAWRAARIQPAEVLRYE
CCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]