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The map label for this gene is rhtB [H]

Identifier: 92113661

GI number: 92113661

Start: 1749821

End: 1750444

Strand: Direct

Name: rhtB [H]

Synonym: Csal_1537

Alternate gene names: 92113661

Gene position: 1749821-1750444 (Clockwise)

Preceding gene: 92113660

Following gene: 92113665

Centisome position: 47.34

GC content: 65.06

Gene sequence:

>624_bases
ATGATCAGCCTGTCGTTGCTTTCGGTCTTCGTGCCGACGTTTTTCATGGTGTCGTTGACCCCGGGCATGTGCATGACGCT
TTCCATGACGCTGGGCATGACGATCGGGGTGCGGCGCGCCTTGTGGATGATGCTCGGCGAGCTGGTGGGCGTTGGCCTGG
TGGCGGTCTCGGCGGTGGTCGGGGTCGCCACCTTGATGCTGCGCTACCCGGAAGTGTTCGCCGTGTTCAAGTGGGTCGGC
GGCGCCTATCTGATCTATCTCGGTGTCATGATGTGGCGCTCCAAAGGGCGCCTGGCGATCCCCGAGGCGAGTGACGCGGT
GCCCGATGTATCGCGGGTCCAGTTGATCGTTCAGGGGTTCGTGACGGCGGTCGCCAATCCCAAGGGATGGGCATTCTTCA
TCGCCTTGCTGCCGCCCTTTCTGGAATCCGGCCGTCCGCTGGCGCCCCAGCTGGTCGCGCTGGTCGGCGTGATCCTGACC
CTGGAGCTGACCTGTCTGCTGATCTATGCCGGCGGCGGGCGCACGGCCAGCCGCTTCCTGCGCCGCAGCGGCAATGTCCA
GCTGCTGAACCGCATTGCCGGCAGCTTGATGGTCGGGGTCGGTATCTGGCTGGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
GCCCACAGACGCTCGACGACATGATCGACTTCATCGTGGCGCGCATTCTCAATCAACTGGGCATTGCGCATGCTCTGATG
CCGCGCTGGGGAGAAGCCAC

Downstream 100 bases:

>100_bases
GTGTTCCGGTGCACGCGGGCATCAGGCATCACACATAGGGCAGCCAGATGACGCGTACCGTCAGCAGCAGCAGCGAGGCC
CCCGCCAGCCACGGCCATGG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MISLSLLSVFVPTFFMVSLTPGMCMTLSMTLGMTIGVRRALWMMLGELVGVGLVAVSAVVGVATLMLRYPEVFAVFKWVG
GAYLIYLGVMMWRSKGRLAIPEASDAVPDVSRVQLIVQGFVTAVANPKGWAFFIALLPPFLESGRPLAPQLVALVGVILT
LELTCLLIYAGGGRTASRFLRRSGNVQLLNRIAGSLMVGVGIWLALG

Sequences:

>Translated_207_residues
MISLSLLSVFVPTFFMVSLTPGMCMTLSMTLGMTIGVRRALWMMLGELVGVGLVAVSAVVGVATLMLRYPEVFAVFKWVG
GAYLIYLGVMMWRSKGRLAIPEASDAVPDVSRVQLIVQGFVTAVANPKGWAFFIALLPPFLESGRPLAPQLVALVGVILT
LELTCLLIYAGGGRTASRFLRRSGNVQLLNRIAGSLMVGVGIWLALG
>Mature_207_residues
MISLSLLSVFVPTFFMVSLTPGMCMTLSMTLGMTIGVRRALWMMLGELVGVGLVAVSAVVGVATLMLRYPEVFAVFKWVG
GAYLIYLGVMMWRSKGRLAIPEASDAVPDVSRVQLIVQGFVTAVANPKGWAFFIALLPPFLESGRPLAPQLVALVGVILT
LELTCLLIYAGGGRTASRFLRRSGNVQLLNRIAGSLMVGVGIWLALG

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=196, Percent_Identity=29.5918367346939, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22163; Mature: 22163

Theoretical pI: Translated: 10.78; Mature: 10.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISLSLLSVFVPTFFMVSLTPGMCMTLSMTLGMTIGVRRALWMMLGELVGVGLVAVSAVV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVATLMLRYPEVFAVFKWVGGAYLIYLGVMMWRSKGRLAIPEASDAVPDVSRVQLIVQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHH
VTAVANPKGWAFFIALLPPFLESGRPLAPQLVALVGVILTLELTCLLIYAGGGRTASRFL
HHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHH
RRSGNVQLLNRIAGSLMVGVGIWLALG
HHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MISLSLLSVFVPTFFMVSLTPGMCMTLSMTLGMTIGVRRALWMMLGELVGVGLVAVSAVV
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVATLMLRYPEVFAVFKWVGGAYLIYLGVMMWRSKGRLAIPEASDAVPDVSRVQLIVQGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHH
VTAVANPKGWAFFIALLPPFLESGRPLAPQLVALVGVILTLELTCLLIYAGGGRTASRFL
HHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHH
RRSGNVQLLNRIAGSLMVGVGIWLALG
HHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]