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The map label for this gene is fabH [H]

Identifier: 92113594

GI number: 92113594

Start: 1668852

End: 1669994

Strand: Direct

Name: fabH [H]

Synonym: Csal_1470

Alternate gene names: 92113594

Gene position: 1668852-1669994 (Clockwise)

Preceding gene: 92113593

Following gene: 92113595

Centisome position: 45.14

GC content: 65.53

Gene sequence:

>1143_bases
ATGACGCACGCGGTCATTACCGGTACCGGCCTTTACACGCCGCCACACGCCATCGACAACGCCACGCTGGTGGCCTCGTT
CAATGCCTGGGTGGATCGCGAAAACGCGCGCTACCAGGAGGCGATCGAGGACGGATGGCGTCAGCCGCTGGAGCATTCCA
GCAGCGAGTTCATCGCCAAGGCATCAGGTATCCAGAGTCGCTATGTGGTGGAGGCGTCGGGCATTCTCGACCCCGACCGC
ATGCGTCCGCACCTGGCGCCCCGGGCCGACGATGCACTCTCCCTGCAGGCCGAGATGGGACTCGACGCGGCGCGCCAGGC
GCTGTCTGCCGCAGGGGTCGAACCCGGCGCGCTGGATACGGTGATCGTGGCCTGCTCCAACCTGCAGCGTCCTTATCCTG
CGGTGGCGGTGGAGCTCCAGGCCGCGTTGGGCGCCGAGGGACATGCCTTCGACATGAACGTCGCGTGCTCGAGCGCCACC
TTCGCCATCGACCAGGCCAACAACGCCATCCGTGCCGGCAGCGTCAAGCGAGTCCTGGTGGTGAGCCCGGAAATCTGCTC
GGCGCACCTCAACTTCCGGGATCGCGACAGTCACTTCATCTTCGGCGATGCCTGCACGGCGGTGCTGCTGGAAGCCGACG
ACGTGGCCTGCGCCGAAGAGCGTTTCGACGTCGTGAGCACGCGCCTGGCGACACGCTTCTCGAACGCGATCCGCAACAAT
TTCGGCTTTCTCGACCGCGTGACCGACCATCCCGTCGACCGGGATCCGGCCTTCGTCTCCGACAAGCTGTTCGTGCAGGA
CGGGCGGCGCGTGTTCAAGGACGTCTGTCCGCTGGTCGCGTCCCTGATCGGCGAACACCTCGACGCCGAGGGGCTGGCCC
CCGACGACCTCAAGCGGCTGTGGCTGCACCAGGCCAATCGTCACATGAACGATCTGATCGCGCGGCGTGTGCTGGGCCGC
GAGCCGAGCCTGGCCGAGGCACCGGTGATTCTCGACCGCTATGCCAACACCAGTTCGGCGGGCTCGATCATCGCCTTCCA
TCTGCACCGGGAAAATCTGGTCGCAGGCGATGTGGGGGTGGTCTGTTCGTTCGGAGCGGGCTACAGTGCGGGCAATGTGA
TATTGCGTAAGGTGAAGGCTTGA

Upstream 100 bases:

>100_bases
GCTGGACGGAACTCACGGGACGGTGACCTCGCGCGCCAGATGACCGCCCCGCGAACGGGGCATCGACGACACCATAACAA
GCGCATCACGGAGCACGCTC

Downstream 100 bases:

>100_bases
TGAAAACGACCAAGTGGCTGGCCGTGGCGTGCATGGCGGCGGCGGTGAGCGGCTGTGCCAGCCAGGGGCAGACGCAGGGC
AATCCCGACGATCCGTGGGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTHAVITGTGLYTPPHAIDNATLVASFNAWVDRENARYQEAIEDGWRQPLEHSSSEFIAKASGIQSRYVVEASGILDPDR
MRPHLAPRADDALSLQAEMGLDAARQALSAAGVEPGALDTVIVACSNLQRPYPAVAVELQAALGAEGHAFDMNVACSSAT
FAIDQANNAIRAGSVKRVLVVSPEICSAHLNFRDRDSHFIFGDACTAVLLEADDVACAEERFDVVSTRLATRFSNAIRNN
FGFLDRVTDHPVDRDPAFVSDKLFVQDGRRVFKDVCPLVASLIGEHLDAEGLAPDDLKRLWLHQANRHMNDLIARRVLGR
EPSLAEAPVILDRYANTSSAGSIIAFHLHRENLVAGDVGVVCSFGAGYSAGNVILRKVKA

Sequences:

>Translated_380_residues
MTHAVITGTGLYTPPHAIDNATLVASFNAWVDRENARYQEAIEDGWRQPLEHSSSEFIAKASGIQSRYVVEASGILDPDR
MRPHLAPRADDALSLQAEMGLDAARQALSAAGVEPGALDTVIVACSNLQRPYPAVAVELQAALGAEGHAFDMNVACSSAT
FAIDQANNAIRAGSVKRVLVVSPEICSAHLNFRDRDSHFIFGDACTAVLLEADDVACAEERFDVVSTRLATRFSNAIRNN
FGFLDRVTDHPVDRDPAFVSDKLFVQDGRRVFKDVCPLVASLIGEHLDAEGLAPDDLKRLWLHQANRHMNDLIARRVLGR
EPSLAEAPVILDRYANTSSAGSIIAFHLHRENLVAGDVGVVCSFGAGYSAGNVILRKVKA
>Mature_379_residues
THAVITGTGLYTPPHAIDNATLVASFNAWVDRENARYQEAIEDGWRQPLEHSSSEFIAKASGIQSRYVVEASGILDPDRM
RPHLAPRADDALSLQAEMGLDAARQALSAAGVEPGALDTVIVACSNLQRPYPAVAVELQAALGAEGHAFDMNVACSSATF
AIDQANNAIRAGSVKRVLVVSPEICSAHLNFRDRDSHFIFGDACTAVLLEADDVACAEERFDVVSTRLATRFSNAIRNNF
GFLDRVTDHPVDRDPAFVSDKLFVQDGRRVFKDVCPLVASLIGEHLDAEGLAPDDLKRLWLHQANRHMNDLIARRVLGRE
PSLAEAPVILDRYANTSSAGSIIAFHLHRENLVAGDVGVVCSFGAGYSAGNVILRKVKA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=342, Percent_Identity=27.1929824561404, Blast_Score=101, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41090; Mature: 40958

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHAVITGTGLYTPPHAIDNATLVASFNAWVDRENARYQEAIEDGWRQPLEHSSSEFIAK
CCCEEEECCCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ASGIQSRYVVEASGILDPDRMRPHLAPRADDALSLQAEMGLDAARQALSAAGVEPGALDT
HCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHCCCCCCCHHH
VIVACSNLQRPYPAVAVELQAALGAEGHAFDMNVACSSATFAIDQANNAIRAGSVKRVLV
HHHHHHCCCCCCCHHHEEEHHHHCCCCCEEEEEEEECCCEEEEECCCCCEECCCCEEEEE
VSPEICSAHLNFRDRDSHFIFGDACTAVLLEADDVACAEERFDVVSTRLATRFSNAIRNN
ECCHHHHHCCCCCCCCCCEEECCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
FGFLDRVTDHPVDRDPAFVSDKLFVQDGRRVFKDVCPLVASLIGEHLDAEGLAPDDLKRL
CCCHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
WLHQANRHMNDLIARRVLGREPSLAEAPVILDRYANTSSAGSIIAFHLHRENLVAGDVGV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCEEECCCHH
VCSFGAGYSAGNVILRKVKA
EEECCCCCCCCHHHHEEECC
>Mature Secondary Structure 
THAVITGTGLYTPPHAIDNATLVASFNAWVDRENARYQEAIEDGWRQPLEHSSSEFIAK
CCEEEECCCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
ASGIQSRYVVEASGILDPDRMRPHLAPRADDALSLQAEMGLDAARQALSAAGVEPGALDT
HCCCCCEEEEEECCCCCHHHCCCCCCCCCCCCEEHHHHCCHHHHHHHHHHCCCCCCCHHH
VIVACSNLQRPYPAVAVELQAALGAEGHAFDMNVACSSATFAIDQANNAIRAGSVKRVLV
HHHHHHCCCCCCCHHHEEEHHHHCCCCCEEEEEEEECCCEEEEECCCCCEECCCCEEEEE
VSPEICSAHLNFRDRDSHFIFGDACTAVLLEADDVACAEERFDVVSTRLATRFSNAIRNN
ECCHHHHHCCCCCCCCCCEEECCHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHC
FGFLDRVTDHPVDRDPAFVSDKLFVQDGRRVFKDVCPLVASLIGEHLDAEGLAPDDLKRL
CCCHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
WLHQANRHMNDLIARRVLGREPSLAEAPVILDRYANTSSAGSIIAFHLHRENLVAGDVGV
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEEEECCCEEECCCHH
VCSFGAGYSAGNVILRKVKA
EEECCCCCCCCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA