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The map label for this gene is adh [H]

Identifier: 92113218

GI number: 92113218

Start: 1233857

End: 1234885

Strand: Direct

Name: adh [H]

Synonym: Csal_1091

Alternate gene names: 92113218

Gene position: 1233857-1234885 (Clockwise)

Preceding gene: 92113217

Following gene: 92113219

Centisome position: 33.38

GC content: 65.21

Gene sequence:

>1029_bases
ATGAAAGCGCTTGTCTATGAGGGAGTGGGGCAGAAGGCCTGGAAAGAGAAGGATCGGCCCGCAATCGAGCAAACCACGGA
TGCCATCGTGCGGGTGACGTATACCACCATTTGCGGCACCGACCTGCACATCCTCAAGGGCGATGTGCCGGCGGTGACGC
CGGGGCGCACCCTGGGCCATGAAGGCATCGGGGTGATCAAGGAAGTTGGCGGGGCCGTCAGCGGCCTCGCGGTCGGCGAT
CAGGTGCTGATCTCGTGCATCACGTCGTGCGGGCACTGCGATTACTGCAAGCAGGGCATGTATGCGCATTGCCGCGATGG
CGGGTGGATTCTCGGTCACAAGATCGATGGCACCCAGGCCGAGGTGGTGCGCATTCCGCATGCCGCCAACAGCCTGTACC
GGTTGCCGCCGGGGCTGGAGCCCGCCGCGGCGCTGATGCTGAGTGACATCCTGCCCACCGGCCACGAGATCGGCGCGTTG
AACGGAGAGGTCTCGCTGGGGGATACCGTGGCCATCGTCGGCTCGGGCCCCATCGGGCTGGCCGCCTTGTTGACCGCGCG
CTTCTATTCGCCGGGGCGCATCATCATGGTCGACCCGGACGAGAATCGCCTGGCCGTGGCGCGGCAACTGGGCGCGACCG
ACACCGTCAGTACCGATCCGGTGGAGACGGTCATGTCGCTTACCGACGGCGAGGGCGTCGACGTGGCCATGGAGGCCGTG
GGTATCCCCGAGACGTTCGATACCTGCCAGCGCATCCTGCGTCCGGGCGGGCGGCTCGCCAACATCGGCGTGCATGGCCG
CAGCGTCGAACTGCGCCTCGAGGAGCTGTGGATCAAGAACGTCACGGTCCGCACCGGGCTGGTGAATACCAATACCATTC
CCGTGCTCATGCGGTTTCTCGAGACCGGCGGCATCGATGCCGAAAGCCTGATCACCCACCGCTTCGCGCTGGACGAGATC
GAAAAGGCGTACGAGGTGTTCTCGCGTGCCGCGTCGGAAAAGGCCATCAAGATGCTGCTGACCGCCTGA

Upstream 100 bases:

>100_bases
GATCGAAAACTTGACCCTGATCAAGCCCTGTTTTTCCGCGCTTTCTATACTCAGGCAAAGGCTTGCCGAGTCGCGGTGGG
CGTTACCCGGGGAAGGGGAT

Downstream 100 bases:

>100_bases
TGGTTGCCGCTCGCTGAACGGACCGGAGAGGCCCGATGTCGATTCGCAATCTGGATGCGTTGTTCGCCCCGGCCACGATC
GCCCTGATCGGGGCGAGCAA

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKALVYEGVGQKAWKEKDRPAIEQTTDAIVRVTYTTICGTDLHILKGDVPAVTPGRTLGHEGIGVIKEVGGAVSGLAVGD
QVLISCITSCGHCDYCKQGMYAHCRDGGWILGHKIDGTQAEVVRIPHAANSLYRLPPGLEPAAALMLSDILPTGHEIGAL
NGEVSLGDTVAIVGSGPIGLAALLTARFYSPGRIIMVDPDENRLAVARQLGATDTVSTDPVETVMSLTDGEGVDVAMEAV
GIPETFDTCQRILRPGGRLANIGVHGRSVELRLEELWIKNVTVRTGLVNTNTIPVLMRFLETGGIDAESLITHRFALDEI
EKAYEVFSRAASEKAIKMLLTA

Sequences:

>Translated_342_residues
MKALVYEGVGQKAWKEKDRPAIEQTTDAIVRVTYTTICGTDLHILKGDVPAVTPGRTLGHEGIGVIKEVGGAVSGLAVGD
QVLISCITSCGHCDYCKQGMYAHCRDGGWILGHKIDGTQAEVVRIPHAANSLYRLPPGLEPAAALMLSDILPTGHEIGAL
NGEVSLGDTVAIVGSGPIGLAALLTARFYSPGRIIMVDPDENRLAVARQLGATDTVSTDPVETVMSLTDGEGVDVAMEAV
GIPETFDTCQRILRPGGRLANIGVHGRSVELRLEELWIKNVTVRTGLVNTNTIPVLMRFLETGGIDAESLITHRFALDEI
EKAYEVFSRAASEKAIKMLLTA
>Mature_342_residues
MKALVYEGVGQKAWKEKDRPAIEQTTDAIVRVTYTTICGTDLHILKGDVPAVTPGRTLGHEGIGVIKEVGGAVSGLAVGD
QVLISCITSCGHCDYCKQGMYAHCRDGGWILGHKIDGTQAEVVRIPHAANSLYRLPPGLEPAAALMLSDILPTGHEIGAL
NGEVSLGDTVAIVGSGPIGLAALLTARFYSPGRIIMVDPDENRLAVARQLGATDTVSTDPVETVMSLTDGEGVDVAMEAV
GIPETFDTCQRILRPGGRLANIGVHGRSVELRLEELWIKNVTVRTGLVNTNTIPVLMRFLETGGIDAESLITHRFALDEI
EKAYEVFSRAASEKAIKMLLTA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=313, Percent_Identity=25.2396166134185, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI71565154, Length=340, Percent_Identity=24.1176470588235, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=25.8152173913043, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI34577061, Length=367, Percent_Identity=25.8855585831063, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI71565152, Length=346, Percent_Identity=24.2774566473988, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI71743840, Length=370, Percent_Identity=23.7837837837838, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI262073058, Length=370, Percent_Identity=23.7837837837838, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1786825, Length=381, Percent_Identity=29.6587926509186, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1790045, Length=352, Percent_Identity=28.4090909090909, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787863, Length=344, Percent_Identity=27.6162790697674, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1788073, Length=325, Percent_Identity=28.9230769230769, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082125, Length=330, Percent_Identity=27.5757575757576, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI226510992, Length=332, Percent_Identity=25.3012048192771, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786552, Length=342, Percent_Identity=29.2397660818713, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788075, Length=360, Percent_Identity=25.8333333333333, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87081918, Length=268, Percent_Identity=30.2238805970149, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1790718, Length=322, Percent_Identity=26.7080745341615, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788407, Length=343, Percent_Identity=24.7813411078717, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=323, Percent_Identity=27.8637770897833, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17562878, Length=324, Percent_Identity=28.0864197530864, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6319955, Length=340, Percent_Identity=27.6470588235294, Blast_Score=109, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322619, Length=340, Percent_Identity=27.6470588235294, Blast_Score=109, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320033, Length=329, Percent_Identity=27.355623100304, Blast_Score=99, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6319258, Length=383, Percent_Identity=25.8485639686684, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323099, Length=336, Percent_Identity=22.9166666666667, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319257, Length=380, Percent_Identity=24.2105263157895, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6323729, Length=343, Percent_Identity=25.3644314868805, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17737897, Length=342, Percent_Identity=28.6549707602339, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17137530, Length=342, Percent_Identity=28.3625730994152, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17737895, Length=372, Percent_Identity=24.7311827956989, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI45551930, Length=330, Percent_Identity=23.6363636363636, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45550770, Length=330, Percent_Identity=23.6363636363636, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221457811, Length=330, Percent_Identity=23.6363636363636, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 36416; Mature: 36416

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALVYEGVGQKAWKEKDRPAIEQTTDAIVRVTYTTICGTDLHILKGDVPAVTPGRTLGH
CCCEEECCCCCHHHHHCCCCHHHHHHHHEEEEEEEEECCCCEEEEECCCCCCCCCCCCCC
EGIGVIKEVGGAVSGLAVGDQVLISCITSCGHCDYCKQGMYAHCRDGGWILGHKIDGTQA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCEEEEEECCCCCE
EVVRIPHAANSLYRLPPGLEPAAALMLSDILPTGHEIGALNGEVSLGDTVAIVGSGPIGL
EEEECCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCEECCCCCEECCCEEEEEECCCHHH
AALLTARFYSPGRIIMVDPDENRLAVARQLGATDTVSTDPVETVMSLTDGEGVDVAMEAV
HHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHC
GIPETFDTCQRILRPGGRLANIGVHGRSVELRLEELWIKNVTVRTGLVNTNTIPVLMRFL
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHHHHHHCEEEEECCCCCCHHHHHHHHH
ETGGIDAESLITHRFALDEIEKAYEVFSRAASEKAIKMLLTA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKALVYEGVGQKAWKEKDRPAIEQTTDAIVRVTYTTICGTDLHILKGDVPAVTPGRTLGH
CCCEEECCCCCHHHHHCCCCHHHHHHHHEEEEEEEEECCCCEEEEECCCCCCCCCCCCCC
EGIGVIKEVGGAVSGLAVGDQVLISCITSCGHCDYCKQGMYAHCRDGGWILGHKIDGTQA
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCCCEEEEEECCCCCE
EVVRIPHAANSLYRLPPGLEPAAALMLSDILPTGHEIGALNGEVSLGDTVAIVGSGPIGL
EEEECCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCEECCCCCEECCCEEEEEECCCHHH
AALLTARFYSPGRIIMVDPDENRLAVARQLGATDTVSTDPVETVMSLTDGEGVDVAMEAV
HHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEHHHC
GIPETFDTCQRILRPGGRLANIGVHGRSVELRLEELWIKNVTVRTGLVNTNTIPVLMRFL
CCCHHHHHHHHHHCCCCCEEEEEECCCEEEEEHHHHHHHCEEEEECCCCCCHHHHHHHHH
ETGGIDAESLITHRFALDEIEKAYEVFSRAASEKAIKMLLTA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2846513 [H]