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The map label for this gene is yycR [H]

Identifier: 92113123

GI number: 92113123

Start: 1118221

End: 1119414

Strand: Direct

Name: yycR [H]

Synonym: Csal_0995

Alternate gene names: 92113123

Gene position: 1118221-1119414 (Clockwise)

Preceding gene: 92113121

Following gene: 92113124

Centisome position: 30.25

GC content: 63.99

Gene sequence:

>1194_bases
ATGAGCACAGCCAACCGTGGCGTCATCTACATGGGCGCCGGCCATGTCGAGGTTCAGCCGATTGCCTTTCCCGAGCTGGC
GCTGGGGGATCGCAAGTGCCAGCACGGCGTGATACTCAAGGTCGTCACCACCAACATATGCGGCAGTGACCAGCACATGG
TGCGCGGGCGTACCACCGCGCCCGCCGGCATGGTGCTGGGACACGAGATCACCGGCGAGGTCATCGAGTGCGGTCGCGAC
GTCGAGTTCGTCAGTGTCGGCGATATCGTTTCGGTTCCTTTCAACATCGCCTGTGGGCGTTGCCGCAACTGCAAGGAAGG
GCAGACGGGCATCTGCCTCAACGTCAATCCGGCTCGCCCGGGTGCCGCTTACGGATATGTCGACATGGGCGGCTGGGTCG
GCGGCCAGTCCGAATACGTCATGGTGCCCTATGCGGACTTCAACCTCTTGAAGTTCCCCGATCGCGACATCGCCATGGAC
AAGATCCGCGACTTGACGTTGCTCTCCGATATCTTCCCGACCGGTTTTCATGGCTGCGCCACCGCCGGTGTCGGCCCCGG
CAGCACCGTTTACATCGCCGGTGCCGGACCGGTCGGGCTGGCTGCGGCGGTCTCCGCCCAGCTGCTGGGAGCCGCCTGCG
TCATCGTCGGCGACATGAACCCGCAGCGTCTCGATCAGGCCAAGAGCTTCGGTTGCGAGACCCTGGATCTGCGCCAGGAC
ACGCCCATGCCCGACATGCTGGAGCCGATCCTCGGTGAACGCGAAGTGGACTCGGCGGTGGATGCGGTGGGCTTCGAGGC
GCGCTGCCATGGCCACAATCATGCCCATGAGCAGCCGGCCACGGTGCTCAATGCCTGCATGGACGTCACCCGGGCCGGTG
GCCAGATCGGGATTCCGGGACTTTACGTCACCGAAGATCCCGGCGCGGACAGTGAGGAAGCGCGGCACGGCAACCTCTCG
ATGCGCCTTGGGCAGGGCTGGGCCAAGTCCCATTCCTTCCACACCGGTCAGTGCCCGGTAATGAAATACCACCGGCAACT
GATGCAGGCGATCCTGTTCGACAAGGTGAACCTCGCCGATGCGGTCAACGTCGAGATCATCTCGTTGGACGATGCGCCGC
GTGGGTATGCGGATTTCGATGGCGGCGTGGCCAAGAAATTCGTCATCGATCCGCACGGCAGCGTGGCCGCCTGA

Upstream 100 bases:

>100_bases
ATGACTCGCTGGGAACAGTCCGCGCCGACAAGAAGGCTATGGTCGAAGAGTGGCGTTCTCGTCGCCACGCCTCTCCCTAT
AAAACCAAAGGACAAGAGCC

Downstream 100 bases:

>100_bases
GCGGCTGGCGCTGGCCCCGGTGCAGGACCGCGGCCAGTGCCGTCATGCATGCCATTCGCGACTGACACCATGGTCTACCC
GACATCGCCCCGCCCGGGTG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSTANRGVIYMGAGHVEVQPIAFPELALGDRKCQHGVILKVVTTNICGSDQHMVRGRTTAPAGMVLGHEITGEVIECGRD
VEFVSVGDIVSVPFNIACGRCRNCKEGQTGICLNVNPARPGAAYGYVDMGGWVGGQSEYVMVPYADFNLLKFPDRDIAMD
KIRDLTLLSDIFPTGFHGCATAGVGPGSTVYIAGAGPVGLAAAVSAQLLGAACVIVGDMNPQRLDQAKSFGCETLDLRQD
TPMPDMLEPILGEREVDSAVDAVGFEARCHGHNHAHEQPATVLNACMDVTRAGGQIGIPGLYVTEDPGADSEEARHGNLS
MRLGQGWAKSHSFHTGQCPVMKYHRQLMQAILFDKVNLADAVNVEIISLDDAPRGYADFDGGVAKKFVIDPHGSVAA

Sequences:

>Translated_397_residues
MSTANRGVIYMGAGHVEVQPIAFPELALGDRKCQHGVILKVVTTNICGSDQHMVRGRTTAPAGMVLGHEITGEVIECGRD
VEFVSVGDIVSVPFNIACGRCRNCKEGQTGICLNVNPARPGAAYGYVDMGGWVGGQSEYVMVPYADFNLLKFPDRDIAMD
KIRDLTLLSDIFPTGFHGCATAGVGPGSTVYIAGAGPVGLAAAVSAQLLGAACVIVGDMNPQRLDQAKSFGCETLDLRQD
TPMPDMLEPILGEREVDSAVDAVGFEARCHGHNHAHEQPATVLNACMDVTRAGGQIGIPGLYVTEDPGADSEEARHGNLS
MRLGQGWAKSHSFHTGQCPVMKYHRQLMQAILFDKVNLADAVNVEIISLDDAPRGYADFDGGVAKKFVIDPHGSVAA
>Mature_396_residues
STANRGVIYMGAGHVEVQPIAFPELALGDRKCQHGVILKVVTTNICGSDQHMVRGRTTAPAGMVLGHEITGEVIECGRDV
EFVSVGDIVSVPFNIACGRCRNCKEGQTGICLNVNPARPGAAYGYVDMGGWVGGQSEYVMVPYADFNLLKFPDRDIAMDK
IRDLTLLSDIFPTGFHGCATAGVGPGSTVYIAGAGPVGLAAAVSAQLLGAACVIVGDMNPQRLDQAKSFGCETLDLRQDT
PMPDMLEPILGEREVDSAVDAVGFEARCHGHNHAHEQPATVLNACMDVTRAGGQIGIPGLYVTEDPGADSEEARHGNLSM
RLGQGWAKSHSFHTGQCPVMKYHRQLMQAILFDKVNLADAVNVEIISLDDAPRGYADFDGGVAKKFVIDPHGSVAA

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=275, Percent_Identity=29.8181818181818, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI4501929, Length=284, Percent_Identity=29.9295774647887, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI34577061, Length=277, Percent_Identity=29.2418772563177, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI156627571, Length=311, Percent_Identity=26.0450160771704, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1786825, Length=397, Percent_Identity=33.2493702770781, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1790045, Length=223, Percent_Identity=33.1838565022422, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1790718, Length=274, Percent_Identity=27.3722627737226, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082125, Length=229, Percent_Identity=30.5676855895196, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI226510992, Length=286, Percent_Identity=28.6713286713287, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787863, Length=215, Percent_Identity=32.5581395348837, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788073, Length=200, Percent_Identity=30.5, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=320, Percent_Identity=26.5625, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562878, Length=239, Percent_Identity=29.2887029288703, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322619, Length=306, Percent_Identity=30.3921568627451, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319955, Length=306, Percent_Identity=30.3921568627451, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319258, Length=259, Percent_Identity=25.0965250965251, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=250, Percent_Identity=29.6, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17737897, Length=277, Percent_Identity=32.8519855595668, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI17137530, Length=277, Percent_Identity=31.0469314079422, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17737895, Length=226, Percent_Identity=26.9911504424779, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR014184
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 42089; Mature: 41958

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTANRGVIYMGAGHVEVQPIAFPELALGDRKCQHGVILKVVTTNICGSDQHMVRGRTTA
CCCCCCCEEEEECCCEEEEECCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCC
PAGMVLGHEITGEVIECGRDVEFVSVGDIVSVPFNIACGRCRNCKEGQTGICLNVNPARP
CCCEEECCHHCHHHHHCCCCEEEEEECCEEECCCEECCCCCCCCCCCCCEEEEECCCCCC
GAAYGYVDMGGWVGGQSEYVMVPYADFNLLKFPDRDIAMDKIRDLTLLSDIFPTGFHGCA
CCEEEEEECCCEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHH
TAGVGPGSTVYIAGAGPVGLAAAVSAQLLGAACVIVGDMNPQRLDQAKSFGCETLDLRQD
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCEEECCCC
TPMPDMLEPILGEREVDSAVDAVGFEARCHGHNHAHEQPATVLNACMDVTRAGGQIGIPG
CCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
LYVTEDPGADSEEARHGNLSMRLGQGWAKSHSFHTGQCPVMKYHRQLMQAILFDKVNLAD
EEEECCCCCCCCHHCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AVNVEIISLDDAPRGYADFDGGVAKKFVIDPHGSVAA
CCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
STANRGVIYMGAGHVEVQPIAFPELALGDRKCQHGVILKVVTTNICGSDQHMVRGRTTA
CCCCCCEEEEECCCEEEEECCCCCHHCCCCCCCCCEEEEEEEECCCCCCCCEECCCCCC
PAGMVLGHEITGEVIECGRDVEFVSVGDIVSVPFNIACGRCRNCKEGQTGICLNVNPARP
CCCEEECCHHCHHHHHCCCCEEEEEECCEEECCCEECCCCCCCCCCCCCEEEEECCCCCC
GAAYGYVDMGGWVGGQSEYVMVPYADFNLLKFPDRDIAMDKIRDLTLLSDIFPTGFHGCA
CCEEEEEECCCEECCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHH
TAGVGPGSTVYIAGAGPVGLAAAVSAQLLGAACVIVGDMNPQRLDQAKSFGCETLDLRQD
CCCCCCCCEEEEECCCCHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHCCCCEEECCCC
TPMPDMLEPILGEREVDSAVDAVGFEARCHGHNHAHEQPATVLNACMDVTRAGGQIGIPG
CCCHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCE
LYVTEDPGADSEEARHGNLSMRLGQGWAKSHSFHTGQCPVMKYHRQLMQAILFDKVNLAD
EEEECCCCCCCCHHCCCCEEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
AVNVEIISLDDAPRGYADFDGGVAKKFVIDPHGSVAA
CCEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]