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The map label for this gene is yfjR [H]

Identifier: 92113088

GI number: 92113088

Start: 1079160

End: 1080041

Strand: Direct

Name: yfjR [H]

Synonym: Csal_0960

Alternate gene names: 92113088

Gene position: 1079160-1080041 (Clockwise)

Preceding gene: 92113086

Following gene: 92113093

Centisome position: 29.19

GC content: 65.76

Gene sequence:

>882_bases
ATGAAGATCGGTTTCATTGGACTGGGTGCCATGGGACGTGGCATGGCGAGTCAGCTACTCGAGGCAGGGCATGAGGTCAC
GGTGTGGAATCGCTCCACCGAAGCCGTCGAGGCCTTGACTCGGAAAGGCGCCAAGGCAGCCAAGACGCCTGCGGATGCGG
CGCGTCACGAGGTGCTGATCAGCATGCTGGCAGACGATCAGGCGGCGCATCAGGTACTGATCGAGAGCAAGGCCGTCGAG
GCGATGAAAAAGGGCAGCGTGCATATCAACATGGCCACGGTGTCGGTGGCCTTTGCGCGTGGCATGACGGCACTGCACGA
CCGCCTGGGCGTGGCCTACATCGCCGCGCCGGTGCTCGGACGTCCGGACGTGGCGGCAGCGGGCAAGCTCAACATCATCG
CTGCCGGTGATCCGGCCCAGCTCGAGCGGGTCAGGTCCGTGCTCGACGCCATGGGCCAAGCCGTATGGCCATTGGGCGAG
TCGCCGGAGCGTGCCAACGTGGTCAAGATCGCGGCGAACTTCATGCTCGCCACCGCCATCGAATCGATGGCCGAGGCCTC
GACGCTGACACGTGCATACGGCATCGAGGCCAGCGATTTTCTCGATGTGGTCACCAATACGCTCTTCGCCTCACCGGCCT
ATCAGGGCTATGGCAAGATGATCGCCGAAGCACGCTTCGAGCCCGCCGGCTTCACGATGCGCCTGGGCCACAAGGATGTC
GGACTGGCCCTGCGTGCGGGAGACGAGCGGCATGTCGCCTTGCCGCTGGGTAGCGCGGTGCGCGATCGGCTGCTCGATGC
CCTGGCGCACGGCGATGGCGAGAAGGACTGGTCGGGGCTCGCCGAGGTGGCCGCGCGCCAGGCCCACCTGGACACGCGCT
AG

Upstream 100 bases:

>100_bases
CCGGGATGAAAGCCCCCTATCGTGTAACGAGGCGTGGGTCCCGTATATTTTTTAGCGTGCTAGTTTGTTCGACGGAATGC
AGCGTTCAAGGAGCAATCGC

Downstream 100 bases:

>100_bases
CCCGCCCTCATGGCGTCAGACGATACAGGCCGGCCTCGCCGCTGTCGGAGGTGAAATACAGCGCTCCATCGTGGTAGGCG
ACCCCGGTGGGGCGGGCCCA

Product: NAD-binding 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKIGFIGLGAMGRGMASQLLEAGHEVTVWNRSTEAVEALTRKGAKAAKTPADAARHEVLISMLADDQAAHQVLIESKAVE
AMKKGSVHINMATVSVAFARGMTALHDRLGVAYIAAPVLGRPDVAAAGKLNIIAAGDPAQLERVRSVLDAMGQAVWPLGE
SPERANVVKIAANFMLATAIESMAEASTLTRAYGIEASDFLDVVTNTLFASPAYQGYGKMIAEARFEPAGFTMRLGHKDV
GLALRAGDERHVALPLGSAVRDRLLDALAHGDGEKDWSGLAEVAARQAHLDTR

Sequences:

>Translated_293_residues
MKIGFIGLGAMGRGMASQLLEAGHEVTVWNRSTEAVEALTRKGAKAAKTPADAARHEVLISMLADDQAAHQVLIESKAVE
AMKKGSVHINMATVSVAFARGMTALHDRLGVAYIAAPVLGRPDVAAAGKLNIIAAGDPAQLERVRSVLDAMGQAVWPLGE
SPERANVVKIAANFMLATAIESMAEASTLTRAYGIEASDFLDVVTNTLFASPAYQGYGKMIAEARFEPAGFTMRLGHKDV
GLALRAGDERHVALPLGSAVRDRLLDALAHGDGEKDWSGLAEVAARQAHLDTR
>Mature_293_residues
MKIGFIGLGAMGRGMASQLLEAGHEVTVWNRSTEAVEALTRKGAKAAKTPADAARHEVLISMLADDQAAHQVLIESKAVE
AMKKGSVHINMATVSVAFARGMTALHDRLGVAYIAAPVLGRPDVAAAGKLNIIAAGDPAQLERVRSVLDAMGQAVWPLGE
SPERANVVKIAANFMLATAIESMAEASTLTRAYGIEASDFLDVVTNTLFASPAYQGYGKMIAEARFEPAGFTMRLGHKDV
GLALRAGDERHVALPLGSAVRDRLLDALAHGDGEKDWSGLAEVAARQAHLDTR

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40556376, Length=281, Percent_Identity=30.2491103202847, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI23308751, Length=288, Percent_Identity=25.6944444444444, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1790315, Length=289, Percent_Identity=33.9100346020761, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI145693186, Length=283, Percent_Identity=32.1554770318021, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786719, Length=284, Percent_Identity=27.8169014084507, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789092, Length=286, Percent_Identity=26.2237762237762, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17557316, Length=266, Percent_Identity=25.9398496240602, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24655230, Length=298, Percent_Identity=28.8590604026846, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19922568, Length=298, Percent_Identity=28.8590604026846, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28574115, Length=287, Percent_Identity=25.7839721254355, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 30928; Mature: 30928

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGFIGLGAMGRGMASQLLEAGHEVTVWNRSTEAVEALTRKGAKAAKTPADAARHEVLI
CEEEEEECCHHCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
SMLADDQAAHQVLIESKAVEAMKKGSVHINMATVSVAFARGMTALHDRLGVAYIAAPVLG
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPDVAAAGKLNIIAAGDPAQLERVRSVLDAMGQAVWPLGESPERANVVKIAANFMLATAI
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ESMAEASTLTRAYGIEASDFLDVVTNTLFASPAYQGYGKMIAEARFEPAGFTMRLGHKDV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLALRAGDERHVALPLGSAVRDRLLDALAHGDGEKDWSGLAEVAARQAHLDTR
CEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIGFIGLGAMGRGMASQLLEAGHEVTVWNRSTEAVEALTRKGAKAAKTPADAARHEVLI
CEEEEEECCHHCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHH
SMLADDQAAHQVLIESKAVEAMKKGSVHINMATVSVAFARGMTALHDRLGVAYIAAPVLG
HHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RPDVAAAGKLNIIAAGDPAQLERVRSVLDAMGQAVWPLGESPERANVVKIAANFMLATAI
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
ESMAEASTLTRAYGIEASDFLDVVTNTLFASPAYQGYGKMIAEARFEPAGFTMRLGHKDV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCC
GLALRAGDERHVALPLGSAVRDRLLDALAHGDGEKDWSGLAEVAARQAHLDTR
CEEEECCCCCEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]