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The map label for this gene is bepF [H]

Identifier: 92113076

GI number: 92113076

Start: 1063164

End: 1064405

Strand: Direct

Name: bepF [H]

Synonym: Csal_0948

Alternate gene names: 92113076

Gene position: 1063164-1064405 (Clockwise)

Preceding gene: 92113073

Following gene: 92113077

Centisome position: 28.76

GC content: 64.9

Gene sequence:

>1242_bases
ATGGAATCCACGACAGGGAATGATCGCCGGGGCCTTCTGGCCGTGGCATTGGCGGGCGTTCTGTTGATGGGCTGCAGCAG
CGACGACGAGGCCCAGCAGCAGGCAGGCGATACTTCCCCGCCACCGAAAAAGGCGCAGGTCATGGAAATGACCAAGCGCG
ATATCGCGCTCGACAAGAGCTATCCCGCCATGCTGCGCAGCGATAACGAGGTGACGGTCGTGGCACGCGTGAGCGGAACT
CTCGAGGAGCGTCATTTCGAGCCCGGACAACAGGTCGAGAAGGGCGAGAGTCTCTATACCATCGAGCCGGAAATCTATCA
GGCGACCGTGCGTCAGCGCGAGGCGGATCTGCAGAGCGCCCAGGCCGATGCGGAGCTGGCGCAGACCAATGCCGACCGTT
ATCAGCGGCTGCTCAAGCAGAACTCGGTCAGCGTGCAGCAGCGCGATCAGGCCCTGGCCGACCTCAAGGTCGCGCGTGCC
AGCGTGGCCCAGGCACAGGCGGCGCTCGACAGTGCGCGCATCGATCTGGATTACACCGATGTCGAGGCGCCCGTGTCGGG
CATGATCAGCCTCAGCGAGGTCAATGTCGGCAATCTGGTGAACGATGGCACCGAATTGGCGACCATCACGCCGCTCGATC
CGTTGGAGGTCCGTTTCCAGCTCCCGCAGGAAGAAGCCTTCGAGTTGCGCCGTCAGCGCCAGCAGCAGGGCAAGGAGGCG
GTGACCGCCGAGCTGGAAATCCCAGCGTTGCCGGGGCAGACCCTGGAAGGACGCGTGGAATTCCTGGGATCGCGGGTCAG
CGAGAGCACCAGCACGGTGCAGGCCAATGCCTTTTTCGACAATCCCGGCGGGCTCTTCCTGCCCGGTCAGTTCGTGCGCG
TCAAGCTGGAAGGCCTGAAGCGCTACGATGTGTTCGCCGTGCCGGAAATCGCCGTGACGCAAGGGCTGATGGGCCCGCAG
GTCTATGTGCTGAGCGATGAGGGCAAGGCGCGCACGCGTACCGTGCAGCTCGGTGACACGGCCGGCCCATGGATGATCAT
CAAGGACGGGCTCGAGGCGGGAGACCGCGTCGTGGTCAGCGATCCGGGCAACATCAGTGCCGGTGCGGCCATCGATCCCC
AGCCTTTCGACGGCGATGCCGAGGCGCTTTCCGACACCGATGGCGAGAGCCGGAAGGCGCCGCCGAATGCCGAGGCGTCG
CCGGATGCGGCGAATCAGGGTCAGCAGGCAAGCGGAGCCTGA

Upstream 100 bases:

>100_bases
TTTTTCGCCATCATACCCTAAGTGCATGGCATTTACATTCATGTATGTATGCGTGTAGTCTTAGCCATCATTGATCTAGA
TCAAACAAGGTAAAACACCG

Downstream 100 bases:

>100_bases
CGGATGAATATCTCCAACTTCTTCATCAAGCGCCCGGTCTTCGCCACCGTCATCTCGATCATCATCGCGGTCATCGGCTT
CATGGCGATGCGCGTGCTGC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MESTTGNDRRGLLAVALAGVLLMGCSSDDEAQQQAGDTSPPPKKAQVMEMTKRDIALDKSYPAMLRSDNEVTVVARVSGT
LEERHFEPGQQVEKGESLYTIEPEIYQATVRQREADLQSAQADAELAQTNADRYQRLLKQNSVSVQQRDQALADLKVARA
SVAQAQAALDSARIDLDYTDVEAPVSGMISLSEVNVGNLVNDGTELATITPLDPLEVRFQLPQEEAFELRRQRQQQGKEA
VTAELEIPALPGQTLEGRVEFLGSRVSESTSTVQANAFFDNPGGLFLPGQFVRVKLEGLKRYDVFAVPEIAVTQGLMGPQ
VYVLSDEGKARTRTVQLGDTAGPWMIIKDGLEAGDRVVVSDPGNISAGAAIDPQPFDGDAEALSDTDGESRKAPPNAEAS
PDAANQGQQASGA

Sequences:

>Translated_413_residues
MESTTGNDRRGLLAVALAGVLLMGCSSDDEAQQQAGDTSPPPKKAQVMEMTKRDIALDKSYPAMLRSDNEVTVVARVSGT
LEERHFEPGQQVEKGESLYTIEPEIYQATVRQREADLQSAQADAELAQTNADRYQRLLKQNSVSVQQRDQALADLKVARA
SVAQAQAALDSARIDLDYTDVEAPVSGMISLSEVNVGNLVNDGTELATITPLDPLEVRFQLPQEEAFELRRQRQQQGKEA
VTAELEIPALPGQTLEGRVEFLGSRVSESTSTVQANAFFDNPGGLFLPGQFVRVKLEGLKRYDVFAVPEIAVTQGLMGPQ
VYVLSDEGKARTRTVQLGDTAGPWMIIKDGLEAGDRVVVSDPGNISAGAAIDPQPFDGDAEALSDTDGESRKAPPNAEAS
PDAANQGQQASGA
>Mature_413_residues
MESTTGNDRRGLLAVALAGVLLMGCSSDDEAQQQAGDTSPPPKKAQVMEMTKRDIALDKSYPAMLRSDNEVTVVARVSGT
LEERHFEPGQQVEKGESLYTIEPEIYQATVRQREADLQSAQADAELAQTNADRYQRLLKQNSVSVQQRDQALADLKVARA
SVAQAQAALDSARIDLDYTDVEAPVSGMISLSEVNVGNLVNDGTELATITPLDPLEVRFQLPQEEAFELRRQRQQQGKEA
VTAELEIPALPGQTLEGRVEFLGSRVSESTSTVQANAFFDNPGGLFLPGQFVRVKLEGLKRYDVFAVPEIAVTQGLMGPQ
VYVLSDEGKARTRTVQLGDTAGPWMIIKDGLEAGDRVVVSDPGNISAGAAIDPQPFDGDAEALSDTDGESRKAPPNAEAS
PDAANQGQQASGA

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=391, Percent_Identity=34.2710997442455, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1789665, Length=353, Percent_Identity=32.2946175637394, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789929, Length=364, Percent_Identity=30.4945054945055, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI87082036, Length=306, Percent_Identity=30.3921568627451, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI87081796, Length=316, Percent_Identity=26.5822784810127, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081951, Length=194, Percent_Identity=29.8969072164948, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44338; Mature: 44338

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTTGNDRRGLLAVALAGVLLMGCSSDDEAQQQAGDTSPPPKKAQVMEMTKRDIALDKS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
YPAMLRSDNEVTVVARVSGTLEERHFEPGQQVEKGESLYTIEPEIYQATVRQREADLQSA
CCHHHCCCCCEEEEEEECCCHHHHCCCCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
QADAELAQTNADRYQRLLKQNSVSVQQRDQALADLKVARASVAQAQAALDSARIDLDYTD
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
VEAPVSGMISLSEVNVGNLVNDGTELATITPLDPLEVRFQLPQEEAFELRRQRQQQGKEA
CCCCHHCCEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCHHH
VTAELEIPALPGQTLEGRVEFLGSRVSESTSTVQANAFFDNPGGLFLPGQFVRVKLEGLK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEECCCCEEEEEEECCC
RYDVFAVPEIAVTQGLMGPQVYVLSDEGKARTRTVQLGDTAGPWMIIKDGLEAGDRVVVS
CCCEEECCHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEE
DPGNISAGAAIDPQPFDGDAEALSDTDGESRKAPPNAEASPDAANQGQQASGA
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MESTTGNDRRGLLAVALAGVLLMGCSSDDEAQQQAGDTSPPPKKAQVMEMTKRDIALDKS
CCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
YPAMLRSDNEVTVVARVSGTLEERHFEPGQQVEKGESLYTIEPEIYQATVRQREADLQSA
CCHHHCCCCCEEEEEEECCCHHHHCCCCCHHHHCCCCEEEECHHHHHHHHHHHHHHHHHH
QADAELAQTNADRYQRLLKQNSVSVQQRDQALADLKVARASVAQAQAALDSARIDLDYTD
HHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCC
VEAPVSGMISLSEVNVGNLVNDGTELATITPLDPLEVRFQLPQEEAFELRRQRQQQGKEA
CCCCHHCCEEEEECCCCCCCCCCCCEEEECCCCCCEEEEECCHHHHHHHHHHHHHCCHHH
VTAELEIPALPGQTLEGRVEFLGSRVSESTSTVQANAFFDNPGGLFLPGQFVRVKLEGLK
EEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCEECCCCEEEEEEECCC
RYDVFAVPEIAVTQGLMGPQVYVLSDEGKARTRTVQLGDTAGPWMIIKDGLEAGDRVVVS
CCCEEECCHHHHHCCCCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEE
DPGNISAGAAIDPQPFDGDAEALSDTDGESRKAPPNAEASPDAANQGQQASGA
CCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]