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The map label for this gene is ltaE [H]

Identifier: 92113008

GI number: 92113008

Start: 989923

End: 990972

Strand: Direct

Name: ltaE [H]

Synonym: Csal_0880

Alternate gene names: 92113008

Gene position: 989923-990972 (Clockwise)

Preceding gene: 92113007

Following gene: 92113009

Centisome position: 26.78

GC content: 63.71

Gene sequence:

>1050_bases
ATGGAACCCGACTGTACGCCCCGCTTTCTGGCCAGCGACAACACTTCGGGCATCTGTCCTCCCGCGCTCGACTACCTGTT
GCGCGCCAACGCCTGCGATGACCTCGCCTATGGCAACGATGCCTGGACGCAGAAGGCTGCCGATCGTTTCCGCGATTTCT
TCGACTACGACTGCGACGTGTTCTTCGTCTTCAACGGCACGGCAGCCAACTCCCTGACGCTGGCGGCCATGGGACAGAGC
TACCATAGCGTCATCTGCCATGAGCTGGCGCATATCGAGACAGATGAGTGCGGCGGGCCGGAATTCTTCTCCAATGGTGC
CAAGCTGCTCACCTGTGCCGGGGCTGACGGCAAGTTGACGCCCGAGGGAATCGAGTCGCTGGTGATGCGGCGCAGCGACA
TTCATTACCCCAAGCCGCGCACGATCTCGCTGACCCAGGCCACCGAGGTCGGCACCGTGTATACGCGCGATGAACTGATG
GCGATTCGGGCCATGGCGGATAAACACGGGTTGCACGTGCACATGGACGGCGCGCGCTTTGCCAATGCCTGCGCGTCGCT
GAAGGCGACGCCGGCGGAATTGACCTGGCAGGCCGGCGTCGATGCACTGTGCTTCTCGGGCACCAAGAATGGCCTGCCGA
TGGGGGAGGCGGTGGTCTTCTTCAATCGCGCCCTGGCGGAAGATTTCGATTATCGCTGCAAGCAGGCGGGACAGCTGGCC
TCCAAGATGCGCTTCATCGCCGCGCCCTGGCTGGGGCTGCTGGAAAGTGGCGCCTGGTTGAGCAATGCCGAACATGCCAA
TGCCATGGCACGTTATCTGGCGGAGGGCTTTGCCGCGCTGCCGGGCGCCCAGCTGATGTTTCCCGCCCAGGCCAACAGCG
TTTTCGTGACGCTGCCGGTCACGGTGCTCGAGGCGCTGCGTGAGCGCGGCTGGACGTTCTACACGTTCATCGGTGCGGGC
GGTGCACGTTTCGTGTGCGCCTGGAACACCACGCAGGCCTTGCTCGATCGCCTGCTCGACGACGCTCGCGAGGCGTTGGC
CGCAGCGTAA

Upstream 100 bases:

>100_bases
GACGCAATTTTTTGCATGATAACGGCAGGCGTTGGCACCCGGCGTCTTCCGTTGCATCGGCAAGCGTCTTTCTTTTCGCC
ACCCATAAGGATACCAAGGC

Downstream 100 bases:

>100_bases
CAGGTACCGACTGGGCGGCGAATGTCTCGCGGACCGCCCAGTATCTTCCCTTTTCCATGACTTTCAACGAACCAATGGCC
GTTCGATGGGCTCTTATAGA

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MEPDCTPRFLASDNTSGICPPALDYLLRANACDDLAYGNDAWTQKAADRFRDFFDYDCDVFFVFNGTAANSLTLAAMGQS
YHSVICHELAHIETDECGGPEFFSNGAKLLTCAGADGKLTPEGIESLVMRRSDIHYPKPRTISLTQATEVGTVYTRDELM
AIRAMADKHGLHVHMDGARFANACASLKATPAELTWQAGVDALCFSGTKNGLPMGEAVVFFNRALAEDFDYRCKQAGQLA
SKMRFIAAPWLGLLESGAWLSNAEHANAMARYLAEGFAALPGAQLMFPAQANSVFVTLPVTVLEALRERGWTFYTFIGAG
GARFVCAWNTTQALLDRLLDDAREALAAA

Sequences:

>Translated_349_residues
MEPDCTPRFLASDNTSGICPPALDYLLRANACDDLAYGNDAWTQKAADRFRDFFDYDCDVFFVFNGTAANSLTLAAMGQS
YHSVICHELAHIETDECGGPEFFSNGAKLLTCAGADGKLTPEGIESLVMRRSDIHYPKPRTISLTQATEVGTVYTRDELM
AIRAMADKHGLHVHMDGARFANACASLKATPAELTWQAGVDALCFSGTKNGLPMGEAVVFFNRALAEDFDYRCKQAGQLA
SKMRFIAAPWLGLLESGAWLSNAEHANAMARYLAEGFAALPGAQLMFPAQANSVFVTLPVTVLEALRERGWTFYTFIGAG
GARFVCAWNTTQALLDRLLDDAREALAAA
>Mature_349_residues
MEPDCTPRFLASDNTSGICPPALDYLLRANACDDLAYGNDAWTQKAADRFRDFFDYDCDVFFVFNGTAANSLTLAAMGQS
YHSVICHELAHIETDECGGPEFFSNGAKLLTCAGADGKLTPEGIESLVMRRSDIHYPKPRTISLTQATEVGTVYTRDELM
AIRAMADKHGLHVHMDGARFANACASLKATPAELTWQAGVDALCFSGTKNGLPMGEAVVFFNRALAEDFDYRCKQAGQLA
SKMRFIAAPWLGLLESGAWLSNAEHANAMARYLAEGFAALPGAQLMFPAQANSVFVTLPVTVLEALRERGWTFYTFIGAG
GARFVCAWNTTQALLDRLLDDAREALAAA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320789, Length=309, Percent_Identity=25.5663430420712, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 37900; Mature: 37900

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPDCTPRFLASDNTSGICPPALDYLLRANACDDLAYGNDAWTQKAADRFRDFFDYDCDV
CCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
FFVFNGTAANSLTLAAMGQSYHSVICHELAHIETDECGGPEFFSNGAKLLTCAGADGKLT
EEEECCCCCCCEEEEHHCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCCC
PEGIESLVMRRSDIHYPKPRTISLTQATEVGTVYTRDELMAIRAMADKHGLHVHMDGARF
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEECCHHH
ANACASLKATPAELTWQAGVDALCFSGTKNGLPMGEAVVFFNRALAEDFDYRCKQAGQLA
HHHHHHCCCCCHHEEHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SKMRFIAAPWLGLLESGAWLSNAEHANAMARYLAEGFAALPGAQLMFPAQANSVFVTLPV
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHH
TVLEALRERGWTFYTFIGAGGARFVCAWNTTQALLDRLLDDAREALAAA
HHHHHHHHCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEPDCTPRFLASDNTSGICPPALDYLLRANACDDLAYGNDAWTQKAADRFRDFFDYDCDV
CCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEE
FFVFNGTAANSLTLAAMGQSYHSVICHELAHIETDECGGPEFFSNGAKLLTCAGADGKLT
EEEECCCCCCCEEEEHHCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCCC
PEGIESLVMRRSDIHYPKPRTISLTQATEVGTVYTRDELMAIRAMADKHGLHVHMDGARF
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHCCCEEEEECCHHH
ANACASLKATPAELTWQAGVDALCFSGTKNGLPMGEAVVFFNRALAEDFDYRCKQAGQLA
HHHHHHCCCCCHHEEHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
SKMRFIAAPWLGLLESGAWLSNAEHANAMARYLAEGFAALPGAQLMFPAQANSVFVTLPV
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHH
TVLEALRERGWTFYTFIGAGGARFVCAWNTTQALLDRLLDDAREALAAA
HHHHHHHHCCCEEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]