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The map label for this gene is katA [H]

Identifier: 92112931

GI number: 92112931

Start: 899460

End: 900923

Strand: Direct

Name: katA [H]

Synonym: Csal_0803

Alternate gene names: 92112931

Gene position: 899460-900923 (Clockwise)

Preceding gene: 92112930

Following gene: 92112933

Centisome position: 24.33

GC content: 61.41

Gene sequence:

>1464_bases
GTGACGCAAGACAATCGCAAGCCGACGACGACAGATGCCGGGATTCCGGTCGCCAGCGACGAGCATTCGCTCTCGGTGGG
CCCCGACGGCCCGCTCGTCCTGCACGATCACTATCTCATCGAGCAGATGGCGAATTTCAACCGCGAACGGATTCCCGAGC
GTCAGCCGCACGCCAAGGGCAGTGGCGCCTTCGGCCACTTCGAGGTGACCGAGGACGTGAGCCGGTACACCAAGGCCGCC
GTTTTCCAGCCCGGTACCAAGACCGACGTGCTGATTCGCTTCTCCACGGTGGCCGGCGAGCGCGGGAGCCCCGATACATG
GCGCGACCCGCGCGGGTTCTCGATCAAGTTCTACACCAGCGAAGGCAATTACGACATGGTGGGGAACAACACGCCGGTGT
TCTTCATCCGGGATCCGATGAAGTTCCAGCACTTCATCCGCTCGCAGAAACGCCGTGCCGACAGCAACCTTCGCGATCAT
GACATGCAATGGGACTTCTGGACGCTGTCGCCGGAGTCCGCCCACCAGGTCACCTGGCTGATGGGAGACCGGGGCATTCC
CAAGACCTGGCGCCACATGAACGGTTATTCCAGCCATACGTACATGTGGGCCAATGCCCAGGGCGAGAAGTTCTGGGTCA
AGTACCACTTCAAGACGGACCAGGGCATCGAGTGCCTGACTCAGGAAGAAGCCGACCGGCTGGCCGGGGAGGACAGTGAC
TACCATACCCGTGACCTGTATGAAGCCATCGAGCGTGGCGACTATCCGAGCTGGACGCTCTACATGCAGATCATGCCGTT
CGCGGATGCGGATACCTATCGCATCAATCCGTTCGACCTGACCAAGGTCTGGCCGCACGACGACTATCCCATGATCAAGG
TCGGCAAGCTGCAGTTGAACCGCAATCCGACCGACAATCATGCCGAGATCGAGCAGGCGGCCTTCGAGCCCAACAACCTC
GTGCCCGGCATCGGCATCAGCCCGGACAAGATGCTCATCGGCCGCGTATTCTCCTATGCCGATGCGCACCGCGCGCGTCT
CGGGGTCAACTACAAGCAGATCCCGGTCAATGCGCCGCAGGCTCCCGTGCACAGTTACAGCAAGGACGGAGCGATGCGCA
TCAACAAGGTGTCGGACCCGGTATATGCCCCCAACTCCAAGGGCGGTCCGGCGGCGGATGGCGAGCGTTATCCCACCGAT
TCCACCTGGGAAGCCAACGGGCAGATGGTGCGTGCGCCCTATGCCTTGCGCAAGGACGACGATGACTACAGCCAGGCCAA
TGCCTTGATCAACAAGGTCATGGACGATGCCGCGCGGGATCGCCTGGTCAACAACGTGGTCGGCCATGTCTCGGGCGGGG
TCAAGGAACCGGTGCTGTCGCGCGTGTTCGAGTACTGGAAGAACATCGATGCCGAGATCGGTCGCCGCATCGAAGAAGGA
GTGAAAGCGAACAAGGCCGGATAA

Upstream 100 bases:

>100_bases
CCCTTCAGTCGATAGCACCATCGCGCCAGCGGTTCGTTTCCAAGGGAAGGACGTGGCGACATGCCGTGCCACATAGAAAA
CATGACGGGGAGAGACCATC

Downstream 100 bases:

>100_bases
CGACGTATCGCGCCTGATTCGCTGGACTGACCGCACGGCCCGCTTCCCTTGAGGAGCGGGCCGTGTTTTTGTCGGGCGTG
CCGGGGCGGGGCTTCCCTCG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MTQDNRKPTTTDAGIPVASDEHSLSVGPDGPLVLHDHYLIEQMANFNRERIPERQPHAKGSGAFGHFEVTEDVSRYTKAA
VFQPGTKTDVLIRFSTVAGERGSPDTWRDPRGFSIKFYTSEGNYDMVGNNTPVFFIRDPMKFQHFIRSQKRRADSNLRDH
DMQWDFWTLSPESAHQVTWLMGDRGIPKTWRHMNGYSSHTYMWANAQGEKFWVKYHFKTDQGIECLTQEEADRLAGEDSD
YHTRDLYEAIERGDYPSWTLYMQIMPFADADTYRINPFDLTKVWPHDDYPMIKVGKLQLNRNPTDNHAEIEQAAFEPNNL
VPGIGISPDKMLIGRVFSYADAHRARLGVNYKQIPVNAPQAPVHSYSKDGAMRINKVSDPVYAPNSKGGPAADGERYPTD
STWEANGQMVRAPYALRKDDDDYSQANALINKVMDDAARDRLVNNVVGHVSGGVKEPVLSRVFEYWKNIDAEIGRRIEEG
VKANKAG

Sequences:

>Translated_487_residues
MTQDNRKPTTTDAGIPVASDEHSLSVGPDGPLVLHDHYLIEQMANFNRERIPERQPHAKGSGAFGHFEVTEDVSRYTKAA
VFQPGTKTDVLIRFSTVAGERGSPDTWRDPRGFSIKFYTSEGNYDMVGNNTPVFFIRDPMKFQHFIRSQKRRADSNLRDH
DMQWDFWTLSPESAHQVTWLMGDRGIPKTWRHMNGYSSHTYMWANAQGEKFWVKYHFKTDQGIECLTQEEADRLAGEDSD
YHTRDLYEAIERGDYPSWTLYMQIMPFADADTYRINPFDLTKVWPHDDYPMIKVGKLQLNRNPTDNHAEIEQAAFEPNNL
VPGIGISPDKMLIGRVFSYADAHRARLGVNYKQIPVNAPQAPVHSYSKDGAMRINKVSDPVYAPNSKGGPAADGERYPTD
STWEANGQMVRAPYALRKDDDDYSQANALINKVMDDAARDRLVNNVVGHVSGGVKEPVLSRVFEYWKNIDAEIGRRIEEG
VKANKAG
>Mature_486_residues
TQDNRKPTTTDAGIPVASDEHSLSVGPDGPLVLHDHYLIEQMANFNRERIPERQPHAKGSGAFGHFEVTEDVSRYTKAAV
FQPGTKTDVLIRFSTVAGERGSPDTWRDPRGFSIKFYTSEGNYDMVGNNTPVFFIRDPMKFQHFIRSQKRRADSNLRDHD
MQWDFWTLSPESAHQVTWLMGDRGIPKTWRHMNGYSSHTYMWANAQGEKFWVKYHFKTDQGIECLTQEEADRLAGEDSDY
HTRDLYEAIERGDYPSWTLYMQIMPFADADTYRINPFDLTKVWPHDDYPMIKVGKLQLNRNPTDNHAEIEQAAFEPNNLV
PGIGISPDKMLIGRVFSYADAHRARLGVNYKQIPVNAPQAPVHSYSKDGAMRINKVSDPVYAPNSKGGPAADGERYPTDS
TWEANGQMVRAPYALRKDDDDYSQANALINKVMDDAARDRLVNNVVGHVSGGVKEPVLSRVFEYWKNIDAEIGRRIEEGV
KANKAG

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=447, Percent_Identity=54.586129753915, Blast_Score=491, Evalue=1e-139,
Organism=Escherichia coli, GI48994891, Length=384, Percent_Identity=44.2708333333333, Blast_Score=330, Evalue=9e-92,
Organism=Caenorhabditis elegans, GI71998444, Length=478, Percent_Identity=48.1171548117155, Blast_Score=461, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI25147792, Length=462, Percent_Identity=48.2683982683983, Blast_Score=434, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI25151141, Length=469, Percent_Identity=47.9744136460554, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6320462, Length=488, Percent_Identity=46.1065573770492, Blast_Score=409, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321525, Length=346, Percent_Identity=47.6878612716763, Blast_Score=331, Evalue=2e-91,
Organism=Drosophila melanogaster, GI17981717, Length=481, Percent_Identity=48.2328482328482, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=484, Percent_Identity=42.5619834710744, Blast_Score=422, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55338; Mature: 55207

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDNRKPTTTDAGIPVASDEHSLSVGPDGPLVLHDHYLIEQMANFNRERIPERQPHAKG
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHCCCHHHCCCCCCCCCC
SGAFGHFEVTEDVSRYTKAAVFQPGTKTDVLIRFSTVAGERGSPDTWRDPRGFSIKFYTS
CCCCCEEEHHHHHHHHHHHHEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEC
EGNYDMVGNNTPVFFIRDPMKFQHFIRSQKRRADSNLRDHDMQWDFWTLSPESAHQVTWL
CCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
MGDRGIPKTWRHMNGYSSHTYMWANAQGEKFWVKYHFKTDQGIECLTQEEADRLAGEDSD
ECCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
YHTRDLYEAIERGDYPSWTLYMQIMPFADADTYRINPFDLTKVWPHDDYPMIKVGKLQLN
CHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEECCEECEEECCCCCCCEEEEEEEEEC
RNPTDNHAEIEQAAFEPNNLVPGIGISPDKMLIGRVFSYADAHRARLGVNYKQIPVNAPQ
CCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
APVHSYSKDGAMRINKVSDPVYAPNSKGGPAADGERYPTDSTWEANGQMVRAPYALRKDD
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
DDYSQANALINKVMDDAARDRLVNNVVGHVSGGVKEPVLSRVFEYWKNIDAEIGRRIEEG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VKANKAG
HHCCCCC
>Mature Secondary Structure 
TQDNRKPTTTDAGIPVASDEHSLSVGPDGPLVLHDHYLIEQMANFNRERIPERQPHAKG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHCCCHHHCCCCCCCCCC
SGAFGHFEVTEDVSRYTKAAVFQPGTKTDVLIRFSTVAGERGSPDTWRDPRGFSIKFYTS
CCCCCEEEHHHHHHHHHHHHEECCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEC
EGNYDMVGNNTPVFFIRDPMKFQHFIRSQKRRADSNLRDHDMQWDFWTLSPESAHQVTWL
CCCEEECCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
MGDRGIPKTWRHMNGYSSHTYMWANAQGEKFWVKYHFKTDQGIECLTQEEADRLAGEDSD
ECCCCCCHHHHHCCCCCCCEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCC
YHTRDLYEAIERGDYPSWTLYMQIMPFADADTYRINPFDLTKVWPHDDYPMIKVGKLQLN
CHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCEEECCEECEEECCCCCCCEEEEEEEEEC
RNPTDNHAEIEQAAFEPNNLVPGIGISPDKMLIGRVFSYADAHRARLGVNYKQIPVNAPQ
CCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCC
APVHSYSKDGAMRINKVSDPVYAPNSKGGPAADGERYPTDSTWEANGQMVRAPYALRKDD
CCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCC
DDYSQANALINKVMDDAARDRLVNNVVGHVSGGVKEPVLSRVFEYWKNIDAEIGRRIEEG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VKANKAG
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]