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The map label for this gene is qseC [H]

Identifier: 92112860

GI number: 92112860

Start: 815952

End: 817355

Strand: Direct

Name: qseC [H]

Synonym: Csal_0728

Alternate gene names: 92112860

Gene position: 815952-817355 (Clockwise)

Preceding gene: 92112859

Following gene: 92112861

Centisome position: 22.07

GC content: 70.01

Gene sequence:

>1404_bases
GTGATCCAGGTGGAAGGCTCACTGAAGGCCCGCCTGGCCGTCTGGCTGGTCGTGACCGTCAGCGCGCTCGGCGTGCTGCT
GCTGGTCGAGGCCTATTTCAGTTCGCAACGCGCAGCCGAGCGCGCCTATGACAGCCAGCTCGAAGCCGCCGCCCTGACCA
TCGCCGAGGCCGTGCAGTGGGAGGCGGGGCAGCCGGTGGTGGAGATTCCCTCGGCGGCGCTGCAGATCCTGGCGACGCGC
CATCAGGAGCGGGTGTTCTACGCCGTGCTGGACGCCGACGGCCAGGCGATCTCGGGCAACCTGAACATGGCGATTCCCTC
CGAGTGGCAACGCCAGGCGGCACTGCAGCCGACATGGTTCAGCGAGACGCATCGCGGCACGCCCTGGCGGCTCCACGGGC
GGGAGCTCGACTCCGCCGGCTGGGAAACCCAGGACCCGGTGCAGATCTGGGTCGGCCACACGATGTCGGGGCGCGACGCC
CTGGCCGAGGCGCTCTTCGAACAGGCGGTCACGCGCTTCGTGATCATGGTGCTGGTGGCGGGCATCCTGATGCTGCTGGC
GATGCGCGTGGCGCTCGCGCCGATGCGTCGCCTGCGCCACCAGTTGCGCCAGCGTGATGCCGACGACATGCGCCCGCTGG
ACACCCGGGTGCCGGAGGAAATGCGTGAAATGGCGGAAACCCTGGATTCGCTCTTCACCCGGCAGCGCGAGAGCCGGGAC
GCCTTGCTGCGCTTTACCGCCGATGCCAGTCATCAGCTCAAGACGCCGCTCGCCGGCCTGCAGGCCACCAGTGAACTGGC
CCTGCAAAGCGAGCACCCCGAGACCTGGCGGCAGGCCCTGGCCGACGTGCACGACAGTGCCGGACGTACCAGCCGCCTGG
CCGGCCAGCTGTTGAGCCTGGCACGCCTGCGCCATGCCGAGGAGGAGGGCGCGGCCACGCGGCTCGACGCGATCGCGCTG
CTGCGCGAGACCGCCTTCGACTGGGCGCAGCGCGACGCGGCGCAAGGGCATGACATCGGCCTGGCCGCCTTGCCCGAGTC
GCCGCAGTACATCTGCGGCGAGGCCTGGGCCCTGCGCGAGCTGCTCGGCAACCTGATCGACAACGCCCTGCGTTATACAC
CGCCGGGCAGCGTGATTACCCTGGGCGCGGTGCGTCACGCGCAGACGCTGGAATGGTATATCGAAGACGACGGCCCCGGT
GTCTCGGCGGAGGTGATGGCGCGCCTGCATCGCCCCTTCGAGCGTGGCGGCCGGCAGGACACCGAGGGCTCCGGCCTGGG
GCTGGCCATCGTGGACTCGATCGTGCGTCGCCACGCGGCGCGGATGCAGGTCGAGTCGGCGGAGAAGGGCGGGCTGAGGG
TCCGCCTGTTGTTTCCTTGTCTCACCCGACACGAGGAGGGGTGA

Upstream 100 bases:

>100_bases
TGGAGGTGTACATCAGCCGCTTGCGCAAACGGCTCGACGGCAGCGGGCTGCGCATTCGCACCTTTCGCGGCATGGGGTAT
CGGCTCGAGGAAGCCGCTTC

Downstream 100 bases:

>100_bases
TGTCGATTCGTCGTGTGGCGTTCGCCTGGCTGCTGGGGGCCCTGGCGCCGAGCCTCGCCTGGGCCGACACCCCGCTCATC
GTCGAGGCTGCGCTCGACAG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MIQVEGSLKARLAVWLVVTVSALGVLLLVEAYFSSQRAAERAYDSQLEAAALTIAEAVQWEAGQPVVEIPSAALQILATR
HQERVFYAVLDADGQAISGNLNMAIPSEWQRQAALQPTWFSETHRGTPWRLHGRELDSAGWETQDPVQIWVGHTMSGRDA
LAEALFEQAVTRFVIMVLVAGILMLLAMRVALAPMRRLRHQLRQRDADDMRPLDTRVPEEMREMAETLDSLFTRQRESRD
ALLRFTADASHQLKTPLAGLQATSELALQSEHPETWRQALADVHDSAGRTSRLAGQLLSLARLRHAEEEGAATRLDAIAL
LRETAFDWAQRDAAQGHDIGLAALPESPQYICGEAWALRELLGNLIDNALRYTPPGSVITLGAVRHAQTLEWYIEDDGPG
VSAEVMARLHRPFERGGRQDTEGSGLGLAIVDSIVRRHAARMQVESAEKGGLRVRLLFPCLTRHEEG

Sequences:

>Translated_467_residues
MIQVEGSLKARLAVWLVVTVSALGVLLLVEAYFSSQRAAERAYDSQLEAAALTIAEAVQWEAGQPVVEIPSAALQILATR
HQERVFYAVLDADGQAISGNLNMAIPSEWQRQAALQPTWFSETHRGTPWRLHGRELDSAGWETQDPVQIWVGHTMSGRDA
LAEALFEQAVTRFVIMVLVAGILMLLAMRVALAPMRRLRHQLRQRDADDMRPLDTRVPEEMREMAETLDSLFTRQRESRD
ALLRFTADASHQLKTPLAGLQATSELALQSEHPETWRQALADVHDSAGRTSRLAGQLLSLARLRHAEEEGAATRLDAIAL
LRETAFDWAQRDAAQGHDIGLAALPESPQYICGEAWALRELLGNLIDNALRYTPPGSVITLGAVRHAQTLEWYIEDDGPG
VSAEVMARLHRPFERGGRQDTEGSGLGLAIVDSIVRRHAARMQVESAEKGGLRVRLLFPCLTRHEEG
>Mature_467_residues
MIQVEGSLKARLAVWLVVTVSALGVLLLVEAYFSSQRAAERAYDSQLEAAALTIAEAVQWEAGQPVVEIPSAALQILATR
HQERVFYAVLDADGQAISGNLNMAIPSEWQRQAALQPTWFSETHRGTPWRLHGRELDSAGWETQDPVQIWVGHTMSGRDA
LAEALFEQAVTRFVIMVLVAGILMLLAMRVALAPMRRLRHQLRQRDADDMRPLDTRVPEEMREMAETLDSLFTRQRESRD
ALLRFTADASHQLKTPLAGLQATSELALQSEHPETWRQALADVHDSAGRTSRLAGQLLSLARLRHAEEEGAATRLDAIAL
LRETAFDWAQRDAAQGHDIGLAALPESPQYICGEAWALRELLGNLIDNALRYTPPGSVITLGAVRHAQTLEWYIEDDGPG
VSAEVMARLHRPFERGGRQDTEGSGLGLAIVDSIVRRHAARMQVESAEKGGLRVRLLFPCLTRHEEG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=462, Percent_Identity=28.7878787878788, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786783, Length=302, Percent_Identity=29.8013245033113, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786600, Length=277, Percent_Identity=29.9638989169675, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=30.5369127516779, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788393, Length=279, Percent_Identity=29.7491039426523, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790346, Length=246, Percent_Identity=28.4552845528455, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787374, Length=300, Percent_Identity=27, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=305, Percent_Identity=23.6065573770492, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=26.8595041322314, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789149, Length=520, Percent_Identity=22.3076923076923, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=20.4166666666667, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=221, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=28.2700421940928, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=297, Percent_Identity=24.9158249158249, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=24.4, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082128, Length=300, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=251, Percent_Identity=25.8964143426295, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51743; Mature: 51743

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQVEGSLKARLAVWLVVTVSALGVLLLVEAYFSSQRAAERAYDSQLEAAALTIAEAVQW
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAGQPVVEIPSAALQILATRHQERVFYAVLDADGQAISGNLNMAIPSEWQRQAALQPTWF
CCCCCHHHCCHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCCCCCCHHHHHHCCCCCCC
SETHRGTPWRLHGRELDSAGWETQDPVQIWVGHTMSGRDALAEALFEQAVTRFVIMVLVA
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GILMLLAMRVALAPMRRLRHQLRQRDADDMRPLDTRVPEEMREMAETLDSLFTRQRESRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCHH
ALLRFTADASHQLKTPLAGLQATSELALQSEHPETWRQALADVHDSAGRTSRLAGQLLSL
HHEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARLRHAEEEGAATRLDAIALLRETAFDWAQRDAAQGHDIGLAALPESPQYICGEAWALRE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHH
LLGNLIDNALRYTPPGSVITLGAVRHAQTLEWYIEDDGPGVSAEVMARLHRPFERGGRQD
HHHHHHHHHHCCCCCCCEEEECHHHHCCEEEEEEECCCCCCHHHHHHHHHCHHHHCCCCC
TEGSGLGLAIVDSIVRRHAARMQVESAEKGGLRVRLLFPCLTRHEEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCC
>Mature Secondary Structure
MIQVEGSLKARLAVWLVVTVSALGVLLLVEAYFSSQRAAERAYDSQLEAAALTIAEAVQW
CEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAGQPVVEIPSAALQILATRHQERVFYAVLDADGQAISGNLNMAIPSEWQRQAALQPTWF
CCCCCHHHCCHHHHHHHHHHHHHEEEEEEEECCCCEEECCCCCCCCCHHHHHHCCCCCCC
SETHRGTPWRLHGRELDSAGWETQDPVQIWVGHTMSGRDALAEALFEQAVTRFVIMVLVA
CCCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GILMLLAMRVALAPMRRLRHQLRQRDADDMRPLDTRVPEEMREMAETLDSLFTRQRESRD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCHH
ALLRFTADASHQLKTPLAGLQATSELALQSEHPETWRQALADVHDSAGRTSRLAGQLLSL
HHEEEECCCCHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARLRHAEEEGAATRLDAIALLRETAFDWAQRDAAQGHDIGLAALPESPQYICGEAWALRE
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHH
LLGNLIDNALRYTPPGSVITLGAVRHAQTLEWYIEDDGPGVSAEVMARLHRPFERGGRQD
HHHHHHHHHHCCCCCCCEEEECHHHHCCEEEEEEECCCCCCHHHHHHHHHCHHHHCCCCC
TEGSGLGLAIVDSIVRRHAARMQVESAEKGGLRVRLLFPCLTRHEEG
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]