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The map label for this gene is oadA [H]

Identifier: 92112825

GI number: 92112825

Start: 775595

End: 777403

Strand: Direct

Name: oadA [H]

Synonym: Csal_0693

Alternate gene names: 92112825

Gene position: 775595-777403 (Clockwise)

Preceding gene: 92112824

Following gene: 92112826

Centisome position: 20.98

GC content: 67.66

Gene sequence:

>1809_bases
ATGAGCGATACTCAACGTCCGCTGGGCATTACCGACGTGGTGCTGCGCGACGCGCACCAATCCCTCTTCGCCACGCGCAT
GCGCCTGGACGACATGCTGCCCATCGCCGAGAAACTCGACCGCGTGGGATTCTGGTCGCTGGAATCCTGGGGCGGCGCGA
CTTTCGACGCCTGCATTCGCTATCTGGGCGAGGACCCCTGGGCGCGTATTCGGGCTCTGAAGGAAGCCATGCCCAACACC
CCGCAGCAGATGCTGCTGCGAGGTCAGAACCTGCTCGGCTATCGGCACTACGCCGACGACGTGGTCGATGCGTTCGTCGA
GCGTGCCCGGGCCAATGGCGTGGATGTGTTCCGGGTCTTCGACGCCATGAACGACACCCGCAATCTGGAACGCGCGCTCA
AGGCCGTGGTGGCTTGCGAGGGACATGCCCAGGGCACCCTGGCGTACACCGTGAGCCCCGTGCACACCCTGGAAAGCTGG
CTGGACATGGCCAAGCGCATCGAGGACATGGGCGCGCACTCGCTGGCGATCAAGGACATGGCCGGTCTGCTGACGCCCTA
CATGGCGCATGAGCTGGTCTCGCGGCTCAAGCAGACCGTGGCCTTGCCCATCCATGTGCATTGCCATGCCACCACGGGGC
TTTCCACCGCGACGCTGCTCAAGGCCGTCGAGGCCGGCGCCGACACCGTCGACACGGCGATCTCGTCGATGGCGATGACC
TACGGCCACAGCCCCACCGAGTCCCTGGTGGCGATGCTGCGCGAGACGCCGCGCGATACCGGGCTCGACCTCGAGCTGCT
CGAGGACATCGCCGCCTATTTTCGTGAGGTGCGCAAGAAATACACGGCGTTCGAAGGCTCACTGCGCGGCATCGACTCGC
GCATCCTGGTGGCGCAGGTGCCCGGCGGCATGCTCACCAACATGGAAGGCCAGCTCAAGGAGCAAGGCGCGGGAGACCGG
CTCGACGAGGTGCTCGGCGAAATTCCCCGCGTGCGCGAGGACCTGGGGTACATTCCCCTGGTCACGCCCACGTCGCAGAT
CGTCGGGACCCAGGCGGTGATGAACGTGATGATGGGCAGCCGCTATCAGTCGATCTCCAAGGAGGTGCAGGCGCTGCTCA
AGGGTGAATACGGCGCCGCGCCGGCGCCCTTCGATGCGGACTTGCAGGCGCGTGCCCTGGCGGGAGAGCAGCCGATCACC
TGCCGACCCGCCGACCGTCTCGCGCCGGAGATGGAACGCCTCGCGGCGGAGCTCAAGGAAAAGGCCGGGACGGACGCGGT
ACGTCTGGCCGAGGGCGAGCGCGAGACCGACGACGTGCTCACCTACGCGCTGTTCCCGCAGATCGGCTTCAAGTTCCTCG
CCCACCGTGACGACCCCTCGGCGTTCGAGCCGGCACCGCAAGCGCCGGGGGAGACGCCGCCGCCATCCCGTGACGAGTCG
CCTGCCACGGCACCGTCCGCCGCGCCCCGCGCGCCTGAAACCTATACCGTCACTGTCAACGGCAAGGCCTACGTGGTCGA
GGTGGCCGAGGGCGGCGAGGTCTCGCAGGTGGCTGCCCGGGCGGACGCGTCGCCCGCGGCGGCGCCTGCGCCGGCCAGCG
GCGAGGCGATCACTGCGCCGCTGGCCGGCAACATCTTCAAGGTCAATGTCGCCGCCGGCGACAGCGTCGCCGAGGGCGAT
GTGGTGATCATCCTCGAGGCGATGAAGATGGAAACCGAAGTGCGCGCGGCACAAGCGGGCACCGTCTCCGCCGTCGCGGT
CAAGGAGGGCGACAGCGTCGCCGTCGGTGACGAACTGATCCGTTTGTGA

Upstream 100 bases:

>100_bases
AAGCGTTACCGCCGTCATCACGGCGATTGAGCGACCCTCTCGCCGCCGCGCATCGACACGCTTCGACAAGACCCCTCATT
CTTCACAATCAGGAAGGGCC

Downstream 100 bases:

>100_bases
GGCGCGTCGCATGGATAAATTGCTAGGCCTATGGCAAGGCTCGGGCCTCTACAACATGAGCATCGGCCAGGCGGCGATGA
TTCTCGTCGGGCTGGTACTG

Product: oxaloacetate decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 602; Mature: 601

Protein sequence:

>602_residues
MSDTQRPLGITDVVLRDAHQSLFATRMRLDDMLPIAEKLDRVGFWSLESWGGATFDACIRYLGEDPWARIRALKEAMPNT
PQQMLLRGQNLLGYRHYADDVVDAFVERARANGVDVFRVFDAMNDTRNLERALKAVVACEGHAQGTLAYTVSPVHTLESW
LDMAKRIEDMGAHSLAIKDMAGLLTPYMAHELVSRLKQTVALPIHVHCHATTGLSTATLLKAVEAGADTVDTAISSMAMT
YGHSPTESLVAMLRETPRDTGLDLELLEDIAAYFREVRKKYTAFEGSLRGIDSRILVAQVPGGMLTNMEGQLKEQGAGDR
LDEVLGEIPRVREDLGYIPLVTPTSQIVGTQAVMNVMMGSRYQSISKEVQALLKGEYGAAPAPFDADLQARALAGEQPIT
CRPADRLAPEMERLAAELKEKAGTDAVRLAEGERETDDVLTYALFPQIGFKFLAHRDDPSAFEPAPQAPGETPPPSRDES
PATAPSAAPRAPETYTVTVNGKAYVVEVAEGGEVSQVAARADASPAAAPAPASGEAITAPLAGNIFKVNVAAGDSVAEGD
VVIILEAMKMETEVRAAQAGTVSAVAVKEGDSVAVGDELIRL

Sequences:

>Translated_602_residues
MSDTQRPLGITDVVLRDAHQSLFATRMRLDDMLPIAEKLDRVGFWSLESWGGATFDACIRYLGEDPWARIRALKEAMPNT
PQQMLLRGQNLLGYRHYADDVVDAFVERARANGVDVFRVFDAMNDTRNLERALKAVVACEGHAQGTLAYTVSPVHTLESW
LDMAKRIEDMGAHSLAIKDMAGLLTPYMAHELVSRLKQTVALPIHVHCHATTGLSTATLLKAVEAGADTVDTAISSMAMT
YGHSPTESLVAMLRETPRDTGLDLELLEDIAAYFREVRKKYTAFEGSLRGIDSRILVAQVPGGMLTNMEGQLKEQGAGDR
LDEVLGEIPRVREDLGYIPLVTPTSQIVGTQAVMNVMMGSRYQSISKEVQALLKGEYGAAPAPFDADLQARALAGEQPIT
CRPADRLAPEMERLAAELKEKAGTDAVRLAEGERETDDVLTYALFPQIGFKFLAHRDDPSAFEPAPQAPGETPPPSRDES
PATAPSAAPRAPETYTVTVNGKAYVVEVAEGGEVSQVAARADASPAAAPAPASGEAITAPLAGNIFKVNVAAGDSVAEGD
VVIILEAMKMETEVRAAQAGTVSAVAVKEGDSVAVGDELIRL
>Mature_601_residues
SDTQRPLGITDVVLRDAHQSLFATRMRLDDMLPIAEKLDRVGFWSLESWGGATFDACIRYLGEDPWARIRALKEAMPNTP
QQMLLRGQNLLGYRHYADDVVDAFVERARANGVDVFRVFDAMNDTRNLERALKAVVACEGHAQGTLAYTVSPVHTLESWL
DMAKRIEDMGAHSLAIKDMAGLLTPYMAHELVSRLKQTVALPIHVHCHATTGLSTATLLKAVEAGADTVDTAISSMAMTY
GHSPTESLVAMLRETPRDTGLDLELLEDIAAYFREVRKKYTAFEGSLRGIDSRILVAQVPGGMLTNMEGQLKEQGAGDRL
DEVLGEIPRVREDLGYIPLVTPTSQIVGTQAVMNVMMGSRYQSISKEVQALLKGEYGAAPAPFDADLQARALAGEQPITC
RPADRLAPEMERLAAELKEKAGTDAVRLAEGERETDDVLTYALFPQIGFKFLAHRDDPSAFEPAPQAPGETPPPSRDESP
ATAPSAAPRAPETYTVTVNGKAYVVEVAEGGEVSQVAARADASPAAAPAPASGEAITAPLAGNIFKVNVAAGDSVAEGDV
VIILEAMKMETEVRAAQAGTVSAVAVKEGDSVAVGDELIRL

Specific function: Lyase and sodium transporter [H]

COG id: COG5016

COG function: function code C; Pyruvate/oxaloacetate carboxyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=630, Percent_Identity=33.6507936507937, Blast_Score=286, Evalue=5e-77,
Organism=Homo sapiens, GI106049295, Length=630, Percent_Identity=33.6507936507937, Blast_Score=286, Evalue=5e-77,
Organism=Homo sapiens, GI106049292, Length=630, Percent_Identity=33.6507936507937, Blast_Score=286, Evalue=5e-77,
Organism=Caenorhabditis elegans, GI17562816, Length=627, Percent_Identity=32.3763955342903, Blast_Score=304, Evalue=1e-82,
Organism=Saccharomyces cerevisiae, GI6319695, Length=629, Percent_Identity=33.0683624801272, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321376, Length=623, Percent_Identity=33.3868378812199, Blast_Score=304, Evalue=3e-83,
Organism=Drosophila melanogaster, GI24652212, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI24652210, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI24652214, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI19921944, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI24652216, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI281363050, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24652224, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24652222, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24652220, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24652218, Length=634, Percent_Identity=32.018927444795, Blast_Score=298, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR003379
- InterPro:   IPR005776
- InterPro:   IPR000891
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =4.1.1.3 [H]

Molecular weight: Translated: 64702; Mature: 64571

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00165 DEHYDRATASE_SER_THR ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTQRPLGITDVVLRDAHQSLFATRMRLDDMLPIAEKLDRVGFWSLESWGGATFDACIR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHH
YLGEDPWARIRALKEAMPNTPQQMLLRGQNLLGYRHYADDVVDAFVERARANGVDVFRVF
HHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DAMNDTRNLERALKAVVACEGHAQGTLAYTVSPVHTLESWLDMAKRIEDMGAHSLAIKDM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLLTPYMAHELVSRLKQTVALPIHVHCHATTGLSTATLLKAVEAGADTVDTAISSMAMT
HHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YGHSPTESLVAMLRETPRDTGLDLELLEDIAAYFREVRKKYTAFEGSLRGIDSRILVAQV
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEEEC
PGGMLTNMEGQLKEQGAGDRLDEVLGEIPRVREDLGYIPLVTPTSQIVGTQAVMNVMMGS
CCCCEECCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHH
RYQSISKEVQALLKGEYGAAPAPFDADLQARALAGEQPITCRPADRLAPEMERLAAELKE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KAGTDAVRLAEGERETDDVLTYALFPQIGFKFLAHRDDPSAFEPAPQAPGETPPPSRDES
HCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PATAPSAAPRAPETYTVTVNGKAYVVEVAEGGEVSQVAARADASPAAAPAPASGEAITAP
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEC
LAGNIFKVNVAAGDSVAEGDVVIILEAMKMETEVRAAQAGTVSAVAVKEGDSVAVGDELI
CCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHH
RL
CC
>Mature Secondary Structure 
SDTQRPLGITDVVLRDAHQSLFATRMRLDDMLPIAEKLDRVGFWSLESWGGATFDACIR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHH
YLGEDPWARIRALKEAMPNTPQQMLLRGQNLLGYRHYADDVVDAFVERARANGVDVFRVF
HHCCCHHHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DAMNDTRNLERALKAVVACEGHAQGTLAYTVSPVHTLESWLDMAKRIEDMGAHSLAIKDM
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGLLTPYMAHELVSRLKQTVALPIHVHCHATTGLSTATLLKAVEAGADTVDTAISSMAMT
HHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHH
YGHSPTESLVAMLRETPRDTGLDLELLEDIAAYFREVRKKYTAFEGSLRGIDSRILVAQV
CCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCEEEEEEC
PGGMLTNMEGQLKEQGAGDRLDEVLGEIPRVREDLGYIPLVTPTSQIVGTQAVMNVMMGS
CCCCEECCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHH
RYQSISKEVQALLKGEYGAAPAPFDADLQARALAGEQPITCRPADRLAPEMERLAAELKE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
KAGTDAVRLAEGERETDDVLTYALFPQIGFKFLAHRDDPSAFEPAPQAPGETPPPSRDES
HCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PATAPSAAPRAPETYTVTVNGKAYVVEVAEGGEVSQVAARADASPAAAPAPASGEAITAP
CCCCCCCCCCCCCEEEEEECCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCCCCCEEEEC
LAGNIFKVNVAAGDSVAEGDVVIILEAMKMETEVRAAQAGTVSAVAVKEGDSVAVGDELI
CCCCEEEEEEECCCCCCCCCEEEEEEHHHHHHHHHHHCCCCEEEEEEECCCCEEECHHHH
RL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2454915 [H]