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The map label for this gene is siaT [H]

Identifier: 92112809

GI number: 92112809

Start: 759663

End: 760985

Strand: Direct

Name: siaT [H]

Synonym: Csal_0677

Alternate gene names: 92112809

Gene position: 759663-760985 (Clockwise)

Preceding gene: 92112808

Following gene: 92112810

Centisome position: 20.55

GC content: 60.54

Gene sequence:

>1323_bases
ATGTCATATGAAATGATCGCCATCGTGATGTTCAGCTCGATGATGCTGATGCTGCTCACCGGACAACGTGTTTTCGGCGC
CATCGGCTTCGTCGGCGCCCTGGCGGGGGTCCTGCTGTGGGGAACCGGTGGAGTGGACATTCCGTTCTCGTCCGCGATGA
AGCTGATGAAATGGTACCCGCTGCTGACCCTGCCAATGTTCATCTTCATGGGGTACGTGCTCTCGGAAAGCCGTATCGCC
GATGACCTCTATCGGATGTTTCATGTCTGGATGGGGCCGATCAAAGGCGGCCTGGCCATTGGCACGATCGGGCTGATGGT
GTTGATCTCGGCCATGAACGGGCTGTCGGTGGCCGGTATGGCGATCGGCGCCACCATCGCCCTGCCCGAACTGCTCCGGC
GCGGGTACGACAAGATCATGGTCACCGGCGTCATCCAGGCGGGGTCCAGTCTCGGCATCCTGGTGCCGCCTTCGGTGGTG
CTGGTGCTGTACGCCATGATCGCGCGCCAGCCCGTAGGACAGTTATGGCTAGCCGGCGTGCTACCGGGGCTGATGATGGC
GACGCTCTTCATCATCTATATCTATGTGCGCTGCCGCTTTCAGCCAAGCCTGGGCCCCGTTCTTCCCGCCGAGGAACGGA
ACGTGTCGCTGGCCGAGAAACTGCGCCTGCTGAGGGCGGGGCTGCTGCCCCTGGTGATCTTTGCGGTGATGATGGTGCCC
TTCGTCAAGGGCTGGACATCCCTGGTCGAAAGTTCGGCGGTCGGCGCGATGGCCGCGCTGCTGGCGGCTATCCTCAAGGG
ACGAATGACGCGCCAGGTCTTCGAGGTATCGGTGCGCAAGACGCTGGCCATTTCCTGCATGTTCATGTGGATCATCCTGG
CAGCCTTGGCCTTCGGGGCCATATTCGACGGCCTGGGGGCGGTGAAGGCCATCGAGGGCCTGTTTACCGAGCGTCTGGGG
CTCTCGCCCTGGACGATTCTGATCCTCATGCAGCTCAGCTTCATCGTCATGGGGACCTTCCTCGACGATACCGCCATGCT
GGTGATCGTGGCGCCACTTTACGTGCCGTTGGTCGAGGCGCTGGGGTTCGATCTGATCTGGTATGGCGTTCTCTACACGA
TCACGACGCAGATCGCCTACATGACGCCGCCATTCGGATACAACCTTTTCCTGATGCGTGCCATGGCGCCCCCGGAGATC
GGGCTGCGTGACATCTATTTATCCATTCTCCCCTTCGTGGCGGTGATGATGACAGCCTTGAGTCTGGTCATGGTCTTTCC
GCAGATCGCCCTTTGGCTTCCAGGCTACATTTATGGGAGTTGA

Upstream 100 bases:

>100_bases
CCATCAAGGTCGTGCTCTGTCTCGGTGTGCTGCTGATGATCCTTCAATCTCTTGCCGAATTTTTCCGGGATGTCGGCCGT
CTGCGCGGGGTGCTCGACTG

Downstream 100 bases:

>100_bases
CAGCAGCGTGACCGAGCAACGATAGCCCTGACAAGGGCCATGTCCATTCGATAGTGACACCAGGAGAGCTACAAAAATGA
CAACAAGACGCAAATTTCTG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSYEMIAIVMFSSMMLMLLTGQRVFGAIGFVGALAGVLLWGTGGVDIPFSSAMKLMKWYPLLTLPMFIFMGYVLSESRIA
DDLYRMFHVWMGPIKGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLRRGYDKIMVTGVIQAGSSLGILVPPSVV
LVLYAMIARQPVGQLWLAGVLPGLMMATLFIIYIYVRCRFQPSLGPVLPAEERNVSLAEKLRLLRAGLLPLVIFAVMMVP
FVKGWTSLVESSAVGAMAALLAAILKGRMTRQVFEVSVRKTLAISCMFMWIILAALAFGAIFDGLGAVKAIEGLFTERLG
LSPWTILILMQLSFIVMGTFLDDTAMLVIVAPLYVPLVEALGFDLIWYGVLYTITTQIAYMTPPFGYNLFLMRAMAPPEI
GLRDIYLSILPFVAVMMTALSLVMVFPQIALWLPGYIYGS

Sequences:

>Translated_440_residues
MSYEMIAIVMFSSMMLMLLTGQRVFGAIGFVGALAGVLLWGTGGVDIPFSSAMKLMKWYPLLTLPMFIFMGYVLSESRIA
DDLYRMFHVWMGPIKGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLRRGYDKIMVTGVIQAGSSLGILVPPSVV
LVLYAMIARQPVGQLWLAGVLPGLMMATLFIIYIYVRCRFQPSLGPVLPAEERNVSLAEKLRLLRAGLLPLVIFAVMMVP
FVKGWTSLVESSAVGAMAALLAAILKGRMTRQVFEVSVRKTLAISCMFMWIILAALAFGAIFDGLGAVKAIEGLFTERLG
LSPWTILILMQLSFIVMGTFLDDTAMLVIVAPLYVPLVEALGFDLIWYGVLYTITTQIAYMTPPFGYNLFLMRAMAPPEI
GLRDIYLSILPFVAVMMTALSLVMVFPQIALWLPGYIYGS
>Mature_439_residues
SYEMIAIVMFSSMMLMLLTGQRVFGAIGFVGALAGVLLWGTGGVDIPFSSAMKLMKWYPLLTLPMFIFMGYVLSESRIAD
DLYRMFHVWMGPIKGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLRRGYDKIMVTGVIQAGSSLGILVPPSVVL
VLYAMIARQPVGQLWLAGVLPGLMMATLFIIYIYVRCRFQPSLGPVLPAEERNVSLAEKLRLLRAGLLPLVIFAVMMVPF
VKGWTSLVESSAVGAMAALLAAILKGRMTRQVFEVSVRKTLAISCMFMWIILAALAFGAIFDGLGAVKAIEGLFTERLGL
SPWTILILMQLSFIVMGTFLDDTAMLVIVAPLYVPLVEALGFDLIWYGVLYTITTQIAYMTPPFGYNLFLMRAMAPPEIG
LRDIYLSILPFVAVMMTALSLVMVFPQIALWLPGYIYGS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=359, Percent_Identity=23.6768802228412, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 47968; Mature: 47837

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
7.7 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
7.5 %Met     (Mature Protein)
8.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SYEMIAIVMFSSMMLMLLTGQRVFGAIGFVGALAGVLLWGTGGVDIPFSSAMKLMKWYP
CHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH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HHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]