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The map label for this gene is rnhB

Identifier: 92112710

GI number: 92112710

Start: 639686

End: 640288

Strand: Direct

Name: rnhB

Synonym: Csal_0577

Alternate gene names: 92112710

Gene position: 639686-640288 (Clockwise)

Preceding gene: 92112709

Following gene: 92112711

Centisome position: 17.3

GC content: 68.66

Gene sequence:

>603_bases
ATGACGGATTTTCCGCCACTGGTGATCGACTACCACGGCTCGCGCCTGGCGGGTGTCGACGAAGTCGGTCGCGGCCCCCT
GGTGGGGGCCGTGGTCGCGGCCGCCGTGATCCTCGATCCGGCTCGTCCCATCGAGGGGCTGGCCGATTCCAAGACCCTCA
GCGAGAAACGCCGCCTGGCCCTGGCGGACGCCATCCGCGAGCAGGCCGCGGCGTGCGCGGTGGCCGAGGCGTCCGCCGAG
GAGATCGATGCGCTCAATATCTTTCATGCCACGCACCTGGCCATGCGCCGGGCCATCGATGCCTTGCCCGTGACGGCGGA
ATATCTGCTGGTGGACGGCAATCGGATGCCGGGGCATCATGTGCCGGGGCAGTGCGTGGTCAAGGGCGACCGCCGCCATG
CGGCGATCGGGGCCGCCTCGATTCTCGCCAAGGTGACGCGCGACGCCCAGATGGTCGCGCTGCACGAACGCCACCCCGAG
TATGGTTTCGCGCGCCACAAGGGCTATCCTACCCGAGAGCATCTCGCGGCCCTCGAACGCCTGGGGCCGTTGGAGGAACA
CCGCCGCTCCTTTGCGCCGGTCAAGCAATGGCAGCTGCTGTAG

Upstream 100 bases:

>100_bases
CCGCGCTGCACGCCACCCTCCAGCGTGGGGCCAGCGAGCGCGCCGCCGAGGCCATCGACAGCCTGGTCGTTCACGGACGC
TTGCCCGAGGAGCCCACGGC

Downstream 100 bases:

>100_bases
TCCCACGCCGCGCCATGCCGTTATCGAATTCATTCAGGAAGGCGTCGCTTCGGCGGTGCCCTCCGCGTCGTTTCAAGAGC
TCGTCATGACAACGCCTTTC

Product: RNase HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLALADAIREQAAACAVAEASAE
EIDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHHVPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPE
YGFARHKGYPTREHLAALERLGPLEEHRRSFAPVKQWQLL

Sequences:

>Translated_200_residues
MTDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLALADAIREQAAACAVAEASAE
EIDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHHVPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPE
YGFARHKGYPTREHLAALERLGPLEEHRRSFAPVKQWQLL
>Mature_199_residues
TDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLALADAIREQAAACAVAEASAEE
IDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHHVPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPEY
GFARHKGYPTREHLAALERLGPLEEHRRSFAPVKQWQLL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=185, Percent_Identity=62.7027027027027, Blast_Score=218, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_CHRSD (Q1R019)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572638.1
- ProteinModelPortal:   Q1R019
- SMR:   Q1R019
- STRING:   Q1R019
- GeneID:   4026314
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0577
- NMPDR:   fig|290398.4.peg.279
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- BioCyc:   CSAL290398:CSAL_0577-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21699; Mature: 21568

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLA
CCCCCCEEEEECCCEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LADAIREQAAACAVAEASAEEIDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHH
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
VPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPEYGFARHKGYPTREHLAALER
CCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
LGPLEEHRRSFAPVKQWQLL
CCCHHHHHHHCCCHHHHCCC
>Mature Secondary Structure 
TDFPPLVIDYHGSRLAGVDEVGRGPLVGAVVAAAVILDPARPIEGLADSKTLSEKRRLA
CCCCCEEEEECCCEECCHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
LADAIREQAAACAVAEASAEEIDALNIFHATHLAMRRAIDALPVTAEYLLVDGNRMPGHH
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
VPGQCVVKGDRRHAAIGAASILAKVTRDAQMVALHERHPEYGFARHKGYPTREHLAALER
CCCCEEEECCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
LGPLEEHRRSFAPVKQWQLL
CCCHHHHHHHCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA