Click here to switch to the map view.

The map label for this gene is ycgM [H]

Identifier: 92112676

GI number: 92112676

Start: 601970

End: 602647

Strand: Direct

Name: ycgM [H]

Synonym: Csal_0543

Alternate gene names: 92112676

Gene position: 601970-602647 (Clockwise)

Preceding gene: 92112675

Following gene: 92112681

Centisome position: 16.28

GC content: 66.96

Gene sequence:

>678_bases
ATGTCCATCCCGGCCCAACCGTTCGTGACTCGCCTGGCCGATGGCGGTGTCTTTCCCCATATGCTGGGCAAGATCGTCTG
CGTGGGGCGCAACTACGCCGAGCACGCCCGTGAACTCGACAACCCGGTGCCCAGTGCGCCGCTGCTATTCATCAAGCCTG
CCACCAGCGCGGTGCCCATGGCACATGACATCGCTGAGCCATTCACGCGTGGCGAGGTACATTTCGAGACGGAGCTGGCG
CTGCTGATCGGCAAGCGTCTGAGCGGGGCGAGTGCCGAAGCCGCGCAGCAAGCGGTCGCGGGCCTCGGGCTGGCGCTGGA
CCTGACGCTGCGCGACGTGCAGTCGCAATTGAAGGAAAAGGGGCACCCCTGGGAAATCGCCAAGGCCTTCGACGGGGCCT
GTCCGCTGTCACCGTTCGTGGCGTTGCACGAGGTGCCCGACTGGGCGGCATTGCGCTTCACGCTGGATATCGACGGCGAG
CGCCGTCAGACCGGCGAGACGCGTGACATGCTGTTCGCGATTCCCGAGTTGCTGGCCGAGATGTCGCGCCACTTCACGTT
GCAGCCCGGCGATGTCGTGCTCACCGGGACGCCGGCCGGTGTGGGCCCCTTGCCGCGCAACGCGCGCTTGTCGCTGCAGG
CCTCGTTCGGGCTGGAGGTCTCCACCCGAACGCGGTGA

Upstream 100 bases:

>100_bases
GAGCAAGAGACCTCCCCGGAGGTCGCAGTGTGAAGCGCCGGCGGTCGCGTTAGACTCGAGTCTTCGCGCCACGGCGCTTT
TTGATTGCCAAGGAGTCTGC

Downstream 100 bases:

>100_bases
CCGGCGAGTCACTCCAGGTAGGTATAACCTTCCAGGCCGGCGGCCAGGTCGTGCATGAACTCGTCGCGCTGGGTGTCGCT
CAAGGCGCTGTCCTGAAGCT

Product: fumarylacetoacetate (FAA) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSIPAQPFVTRLADGGVFPHMLGKIVCVGRNYAEHARELDNPVPSAPLLFIKPATSAVPMAHDIAEPFTRGEVHFETELA
LLIGKRLSGASAEAAQQAVAGLGLALDLTLRDVQSQLKEKGHPWEIAKAFDGACPLSPFVALHEVPDWAALRFTLDIDGE
RRQTGETRDMLFAIPELLAEMSRHFTLQPGDVVLTGTPAGVGPLPRNARLSLQASFGLEVSTRTR

Sequences:

>Translated_225_residues
MSIPAQPFVTRLADGGVFPHMLGKIVCVGRNYAEHARELDNPVPSAPLLFIKPATSAVPMAHDIAEPFTRGEVHFETELA
LLIGKRLSGASAEAAQQAVAGLGLALDLTLRDVQSQLKEKGHPWEIAKAFDGACPLSPFVALHEVPDWAALRFTLDIDGE
RRQTGETRDMLFAIPELLAEMSRHFTLQPGDVVLTGTPAGVGPLPRNARLSLQASFGLEVSTRTR
>Mature_224_residues
SIPAQPFVTRLADGGVFPHMLGKIVCVGRNYAEHARELDNPVPSAPLLFIKPATSAVPMAHDIAEPFTRGEVHFETELAL
LIGKRLSGASAEAAQQAVAGLGLALDLTLRDVQSQLKEKGHPWEIAKAFDGACPLSPFVALHEVPDWAALRFTLDIDGER
RQTGETRDMLFAIPELLAEMSRHFTLQPGDVVLTGTPAGVGPLPRNARLSLQASFGLEVSTRTR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=187, Percent_Identity=45.4545454545455, Blast_Score=181, Evalue=4e-46,
Organism=Homo sapiens, GI66348062, Length=184, Percent_Identity=46.195652173913, Blast_Score=181, Evalue=4e-46,
Organism=Homo sapiens, GI215422413, Length=184, Percent_Identity=46.195652173913, Blast_Score=181, Evalue=4e-46,
Organism=Homo sapiens, GI156231349, Length=180, Percent_Identity=41.1111111111111, Blast_Score=136, Evalue=1e-32,
Organism=Homo sapiens, GI40786394, Length=180, Percent_Identity=40, Blast_Score=130, Evalue=9e-31,
Organism=Escherichia coli, GI1787428, Length=210, Percent_Identity=48.0952380952381, Blast_Score=192, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17557057, Length=184, Percent_Identity=42.3913043478261, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324161, Length=222, Percent_Identity=36.036036036036, Blast_Score=144, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=177, Percent_Identity=37.2881355932203, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI28572127, Length=182, Percent_Identity=32.967032967033, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24663695, Length=181, Percent_Identity=34.8066298342541, Blast_Score=99, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 24275; Mature: 24144

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPAQPFVTRLADGGVFPHMLGKIVCVGRNYAEHARELDNPVPSAPLLFIKPATSAVPM
CCCCCCHHHHHHHCCCCCHHHHHHEEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCH
AHDIAEPFTRGEVHFETELALLIGKRLSGASAEAAQQAVAGLGLALDLTLRDVQSQLKEK
HHHHHCHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHC
GHPWEIAKAFDGACPLSPFVALHEVPDWAALRFTLDIDGERRQTGETRDMLFAIPELLAE
CCCEEHHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MSRHFTLQPGDVVLTGTPAGVGPLPRNARLSLQASFGLEVSTRTR
HHHCEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCEEEECCCC
>Mature Secondary Structure 
SIPAQPFVTRLADGGVFPHMLGKIVCVGRNYAEHARELDNPVPSAPLLFIKPATSAVPM
CCCCCHHHHHHHCCCCCHHHHHHEEEECCCHHHHHHHHCCCCCCCCEEEEECCCCCCCH
AHDIAEPFTRGEVHFETELALLIGKRLSGASAEAAQQAVAGLGLALDLTLRDVQSQLKEK
HHHHHCHHHCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHC
GHPWEIAKAFDGACPLSPFVALHEVPDWAALRFTLDIDGERRQTGETRDMLFAIPELLAE
CCCEEHHHHCCCCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
MSRHFTLQPGDVVLTGTPAGVGPLPRNARLSLQASFGLEVSTRTR
HHHCEECCCCCEEEECCCCCCCCCCCCCEEEEEEECCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]