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The map label for this gene is coaX

Identifier: 92112540

GI number: 92112540

Start: 461260

End: 462099

Strand: Direct

Name: coaX

Synonym: Csal_0407

Alternate gene names: 92112540

Gene position: 461260-462099 (Clockwise)

Preceding gene: 92112539

Following gene: 92112541

Centisome position: 12.48

GC content: 65.83

Gene sequence:

>840_bases
ATGATTCTGGACCTGGATATCGGCAATACGCTCTCCAAGTGGCGCCTGAAGGATGTCGCCAGCAGCGAGATCCGCTCACG
CGGTGCCGTGTGGACGCGCGAGGAGTGGCGCCCGGGTGCCGACATACCGGACCTCGATGTGGTCGAGGCGGTACGGATAT
CGAGCGTGGCTCGGGCCTCGGTGCTGCGCGATACGGTGGCGCTGTTGCGTCGGCAGGTCGGCGCCGTGCATGTCGCGCGC
TCGACGCCGGAGGCCCTGGGCGTCAGCTGCGGGTATGAAGAGCCCGCCCGCCTGGGGGTCGATCGCTGGATGGGAGTGCT
CGCCGGCTATCAGCTGACGGGCGGTTGCTGTAGCGTCGATTGCGGCAGTGCGATCACCATGGACTTCGTGCTGCCCGGTG
GCCGTCACCTGGGGGGGTACATCATTCCCGGGCTGCGCTTGATGAAGGAAAGCCTCAAGTTGGGGACGCGCAACGTGGCC
ATCGATCCCGACAGCGAGGCGGACGAGCTGCTGGCCCCCGGCCGCAATACCGTCGAGGCGGTCAATCACGGTATCTACAT
GTCAGCGGTGAGTGCCGTCAATCGTATCTACAGTGAAGTGTGCGATCGCGAGGGTGTGGCGCTACCGCTGTTGCTCACGG
GCGGGGATGCACGGGTCGTGTCGCGGGGACTGCGTGTCCCTCATGCGATATGGCCCGACATGGTCTATGCAGGACTCGAA
ACCTGCTTCCCGATGACGGCCGCCGAGCGTGCCGGGCGACTGTCCGGTGCGCCGCCCCCGCCGCCAGCGCCGCCATTGGA
AAAAGTGCGTGCCAGCCTTGCATTCTCGATGCTGCTTTGA

Upstream 100 bases:

>100_bases
CGGTGGCCGAGGGGGTGGATGATACCGGCAACCTGCGCGTCAACGTCGACGGACAAGCCCGGCTCCTGGCCGGTGGTGAA
ATCAGCCTGCGCCTACGCTC

Downstream 100 bases:

>100_bases
CACAATGCTGCGCGTTTCGGGCCGACGGAGTCGCGGCGAGAGAAAAAGCATTGTAAAATAAGTGCTTGACACATCTCTCA
AAAGCCGTAGAATTCGTCGC

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MILDLDIGNTLSKWRLKDVASSEIRSRGAVWTREEWRPGADIPDLDVVEAVRISSVARASVLRDTVALLRRQVGAVHVAR
STPEALGVSCGYEEPARLGVDRWMGVLAGYQLTGGCCSVDCGSAITMDFVLPGGRHLGGYIIPGLRLMKESLKLGTRNVA
IDPDSEADELLAPGRNTVEAVNHGIYMSAVSAVNRIYSEVCDREGVALPLLLTGGDARVVSRGLRVPHAIWPDMVYAGLE
TCFPMTAAERAGRLSGAPPPPPAPPLEKVRASLAFSMLL

Sequences:

>Translated_279_residues
MILDLDIGNTLSKWRLKDVASSEIRSRGAVWTREEWRPGADIPDLDVVEAVRISSVARASVLRDTVALLRRQVGAVHVAR
STPEALGVSCGYEEPARLGVDRWMGVLAGYQLTGGCCSVDCGSAITMDFVLPGGRHLGGYIIPGLRLMKESLKLGTRNVA
IDPDSEADELLAPGRNTVEAVNHGIYMSAVSAVNRIYSEVCDREGVALPLLLTGGDARVVSRGLRVPHAIWPDMVYAGLE
TCFPMTAAERAGRLSGAPPPPPAPPLEKVRASLAFSMLL
>Mature_279_residues
MILDLDIGNTLSKWRLKDVASSEIRSRGAVWTREEWRPGADIPDLDVVEAVRISSVARASVLRDTVALLRRQVGAVHVAR
STPEALGVSCGYEEPARLGVDRWMGVLAGYQLTGGCCSVDCGSAITMDFVLPGGRHLGGYIIPGLRLMKESLKLGTRNVA
IDPDSEADELLAPGRNTVEAVNHGIYMSAVSAVNRIYSEVCDREGVALPLLLTGGDARVVSRGLRVPHAIWPDMVYAGLE
TCFPMTAAERAGRLSGAPPPPPAPPLEKVRASLAFSMLL

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_CHRSD (Q1R0I9)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572468.1
- ProteinModelPortal:   Q1R0I9
- SMR:   Q1R0I9
- STRING:   Q1R0I9
- GeneID:   4026102
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0407
- NMPDR:   fig|290398.4.peg.549
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   YLEYERL
- BioCyc:   CSAL290398:CSAL_0407-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 29880; Mature: 29880

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 101-101 BINDING 92-92 BINDING 123-123 BINDING 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDLDIGNTLSKWRLKDVASSEIRSRGAVWTREEWRPGADIPDLDVVEAVRISSVARAS
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VLRDTVALLRRQVGAVHVARSTPEALGVSCGYEEPARLGVDRWMGVLAGYQLTGGCCSVD
HHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCC
CGSAITMDFVLPGGRHLGGYIIPGLRLMKESLKLGTRNVAIDPDSEADELLAPGRNTVEA
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCHHHHH
VNHGIYMSAVSAVNRIYSEVCDREGVALPLLLTGGDARVVSRGLRVPHAIWPDMVYAGLE
HHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHH
TCFPMTAAERAGRLSGAPPPPPAPPLEKVRASLAFSMLL
HHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILDLDIGNTLSKWRLKDVASSEIRSRGAVWTREEWRPGADIPDLDVVEAVRISSVARAS
CEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHH
VLRDTVALLRRQVGAVHVARSTPEALGVSCGYEEPARLGVDRWMGVLAGYQLTGGCCSVD
HHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEECCC
CGSAITMDFVLPGGRHLGGYIIPGLRLMKESLKLGTRNVAIDPDSEADELLAPGRNTVEA
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCHHHHH
VNHGIYMSAVSAVNRIYSEVCDREGVALPLLLTGGDARVVSRGLRVPHAIWPDMVYAGLE
HHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHH
TCFPMTAAERAGRLSGAPPPPPAPPLEKVRASLAFSMLL
HHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA