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The map label for this gene is yhdN [H]

Identifier: 92112515

GI number: 92112515

Start: 426599

End: 427597

Strand: Direct

Name: yhdN [H]

Synonym: Csal_0382

Alternate gene names: 92112515

Gene position: 426599-427597 (Clockwise)

Preceding gene: 92112513

Following gene: 92112516

Centisome position: 11.54

GC content: 66.57

Gene sequence:

>999_bases
ATGGAAAGCATCACCATACCGGGGACCGACCTCACGCCATCACGAGTGGGGCTCGGCACCTGGGCCATCGGTGGTTGGAA
ATGGGGCGGTGCCGATGACGCCAATGCGGTGCGTACCATTCATGCCGCCCTGGATCGCGGCATTACGCTGATCGATACCG
CGCCGGCCTATGGGTTCGGGCATTCCGAGGAGGTCGTCGGTCGGGCGCTGGCCGAGTACGGGCAGCGTGACAAGGTGGTG
CTCGCCACCAAGACGGCGCTCGAGTGGCAGGAAGGCAGCGACGGCGTGGTCCGCAATGCCTCGGCGGCGCGCATCGAAAA
GGAAGTGGAAGACTCGCTGCGGCGCCTGCGCACCGAAGCGATCGATCTGTACCAGATCCATTGGCCGGACCCCCGTGTGC
CGATGGAAGAAACCGCCAGCGCCATGCAGCGCCTCTATCGTGACGGCAAGATCCGCGCGATCGGCGTCAGCAACTTCAGC
GCCGAGCAATGCGATGCCTTTCGCCGGGTGGCGCCGCTGCACAGCGTGCAGCCGCCGCTCAACCTGTTCGAGCGCGACGC
CGAGCGCGACATCATTCCCTATGCGCGGCGCGAGGGGCTGGTCTTTCTGGCCTATGGTGCGCTGTGCCGCGGTCTGCTGA
CGGGCAAGATGCACGCGGATTCGGCCTTCACCGGCGACGATCTGCGTCAATCCGATCCCAAGTTCCAGTCCCCCCGTTTC
ACGCAGTACCTGGCGGCGGTCGAGGCGCTGACACAGCTCGCCCGCGAGCGTCACGACAAGCCGGTATTGGCCCTGGCGGT
GCGCTGGGTGCTCGACTCCCATCCCAATGCCATCGCTCTGTGGGGGGCGCGGCGTCCGGACCAGGTGACGCCCCTGGACG
CGCTTGACGGCTGGTCGCTGACTGCCAGCGATCTGCGCGATATCGATGCCATCATCGACGAGCACGTCACAGACCCCGTG
GGCCCCGAGTTCATGGCACCTCCCGCGCGGGAGGACTGA

Upstream 100 bases:

>100_bases
GGCCAGAATTCGTTGCTTGTCAAAGCCACCGCCGGCGACCACGCTTGATAGCGTTTCGAGGCAGCGGCACGCATGCCGTC
GACAGGCAAAGGAGAGCAAC

Downstream 100 bases:

>100_bases
TCGTCGCCCGGGCGGCCGTCTTCACGCGAGATGCAGGTGACGGTCGCCATTTCGTCATCAATCAGGAGAGCCAACATGGA
GTATCGTCATCTCGGCCAGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MESITIPGTDLTPSRVGLGTWAIGGWKWGGADDANAVRTIHAALDRGITLIDTAPAYGFGHSEEVVGRALAEYGQRDKVV
LATKTALEWQEGSDGVVRNASAARIEKEVEDSLRRLRTEAIDLYQIHWPDPRVPMEETASAMQRLYRDGKIRAIGVSNFS
AEQCDAFRRVAPLHSVQPPLNLFERDAERDIIPYARREGLVFLAYGALCRGLLTGKMHADSAFTGDDLRQSDPKFQSPRF
TQYLAAVEALTQLARERHDKPVLALAVRWVLDSHPNAIALWGARRPDQVTPLDALDGWSLTASDLRDIDAIIDEHVTDPV
GPEFMAPPARED

Sequences:

>Translated_332_residues
MESITIPGTDLTPSRVGLGTWAIGGWKWGGADDANAVRTIHAALDRGITLIDTAPAYGFGHSEEVVGRALAEYGQRDKVV
LATKTALEWQEGSDGVVRNASAARIEKEVEDSLRRLRTEAIDLYQIHWPDPRVPMEETASAMQRLYRDGKIRAIGVSNFS
AEQCDAFRRVAPLHSVQPPLNLFERDAERDIIPYARREGLVFLAYGALCRGLLTGKMHADSAFTGDDLRQSDPKFQSPRF
TQYLAAVEALTQLARERHDKPVLALAVRWVLDSHPNAIALWGARRPDQVTPLDALDGWSLTASDLRDIDAIIDEHVTDPV
GPEFMAPPARED
>Mature_332_residues
MESITIPGTDLTPSRVGLGTWAIGGWKWGGADDANAVRTIHAALDRGITLIDTAPAYGFGHSEEVVGRALAEYGQRDKVV
LATKTALEWQEGSDGVVRNASAARIEKEVEDSLRRLRTEAIDLYQIHWPDPRVPMEETASAMQRLYRDGKIRAIGVSNFS
AEQCDAFRRVAPLHSVQPPLNLFERDAERDIIPYARREGLVFLAYGALCRGLLTGKMHADSAFTGDDLRQSDPKFQSPRF
TQYLAAVEALTQLARERHDKPVLALAVRWVLDSHPNAIALWGARRPDQVTPLDALDGWSLTASDLRDIDAIIDEHVTDPV
GPEFMAPPARED

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI41327764, Length=244, Percent_Identity=32.3770491803279, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27436969, Length=320, Percent_Identity=27.8125, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4504825, Length=320, Percent_Identity=27.8125, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223718702, Length=183, Percent_Identity=34.4262295081967, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI27436964, Length=335, Percent_Identity=26.5671641791045, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI27436962, Length=322, Percent_Identity=26.7080745341615, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI27436966, Length=327, Percent_Identity=26.9113149847095, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41152114, Length=182, Percent_Identity=32.967032967033, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI27436971, Length=333, Percent_Identity=25.5255255255255, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI223718708, Length=131, Percent_Identity=34.3511450381679, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788070, Length=304, Percent_Identity=36.5131578947368, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI87081735, Length=224, Percent_Identity=34.8214285714286, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789199, Length=349, Percent_Identity=30.6590257879656, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789375, Length=316, Percent_Identity=28.1645569620253, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788081, Length=208, Percent_Identity=33.6538461538462, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI48994888, Length=176, Percent_Identity=30.6818181818182, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786400, Length=201, Percent_Identity=29.3532338308458, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082198, Length=172, Percent_Identity=31.3953488372093, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=231, Percent_Identity=29.004329004329, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=217, Percent_Identity=28.110599078341, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71998625, Length=221, Percent_Identity=28.9592760180996, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17552492, Length=210, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323998, Length=305, Percent_Identity=28.8524590163934, Blast_Score=103, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=27.9461279461279, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6325169, Length=296, Percent_Identity=28.3783783783784, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322615, Length=257, Percent_Identity=27.6264591439689, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=290, Percent_Identity=25.8620689655172, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=35.5828220858896, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646159, Length=163, Percent_Identity=30.6748466257669, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36698; Mature: 36698

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESITIPGTDLTPSRVGLGTWAIGGWKWGGADDANAVRTIHAALDRGITLIDTAPAYGFG
CCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCC
HSEEVVGRALAEYGQRDKVVLATKTALEWQEGSDGVVRNASAARIEKEVEDSLRRLRTEA
CHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHH
IDLYQIHWPDPRVPMEETASAMQRLYRDGKIRAIGVSNFSAEQCDAFRRVAPLHSVQPPL
HEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCH
NLFERDAERDIIPYARREGLVFLAYGALCRGLLTGKMHADSAFTGDDLRQSDPKFQSPRF
HHHHHCCCCCCCCHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHH
TQYLAAVEALTQLARERHDKPVLALAVRWVLDSHPNAIALWGARRPDQVTPLDALDGWSL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
TASDLRDIDAIIDEHVTDPVGPEFMAPPARED
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MESITIPGTDLTPSRVGLGTWAIGGWKWGGADDANAVRTIHAALDRGITLIDTAPAYGFG
CCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCC
HSEEVVGRALAEYGQRDKVVLATKTALEWQEGSDGVVRNASAARIEKEVEDSLRRLRTEA
CHHHHHHHHHHHHCCCCCEEEEEECHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHH
IDLYQIHWPDPRVPMEETASAMQRLYRDGKIRAIGVSNFSAEQCDAFRRVAPLHSVQPPL
HEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCH
NLFERDAERDIIPYARREGLVFLAYGALCRGLLTGKMHADSAFTGDDLRQSDPKFQSPRF
HHHHHCCCCCCCCHHHHCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCHH
TQYLAAVEALTQLARERHDKPVLALAVRWVLDSHPNAIALWGARRPDQVTPLDALDGWSL
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCC
TASDLRDIDAIIDEHVTDPVGPEFMAPPARED
CHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]