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The map label for this gene is siaT [H]

Identifier: 92112467

GI number: 92112467

Start: 371330

End: 372634

Strand: Direct

Name: siaT [H]

Synonym: Csal_0334

Alternate gene names: 92112467

Gene position: 371330-372634 (Clockwise)

Preceding gene: 92112466

Following gene: 92112468

Centisome position: 10.05

GC content: 62.68

Gene sequence:

>1305_bases
ATGAGTACCGAGCTGGTGGGTGCCCTGGGCATCCTGGCGCTGTTGGCGCTTCTGGTACTGCGAATTCCCGTGGCCTTCGC
GATCTTCGTGGTGGGCTTCGGGGGAATCACCGTGCTCGACAGCCTCAATTCCGCCTTGAGCCTGTTGGCCAGCGAAACCT
TTACGATCGCCTCGAACGCCGAGCTGATCGTCATTCCCTTGTTCATCTTGATGGGCAATATCGCCACCGAGGCGGGCATG
AGCCGCAAGCTTTATGATGCCGCCTATGCGCTCATCGGCTCGGTGCGGGGCGGTCTGGCGTCGGCCACGGTGGTGGGGTG
TGCCGGCTTCGCCGCGCTCTGCGGCTCCTCCGTGGCATCGGCACTGACCATGGGGCGCGTCTCGCTCAGCGAGATGGAGC
GTTTCAACTACAGCGCCAAGCTGTCCACGGGCTCGGTGGCGGCCGGGGGGACGCTGGGGATCCTCATTCCTCCTTCCACC
GGCTTCGTGATCTACGCCATCTTGACGCAGCAGTCCATCGGCCGCCTGTTCCTGGCGGGCGTGTTGCCCGGGATCATGCT
GTGTCTGCTGTTCGTGCTCCTGATCATGCTGCTGGCCACCATCAAGCCGGTTCTCGCGCCCTCCGGTCCCAAGACGTCAT
GGCGCGAGAAGCAGCAGGGGCTGCTGGGCGCGATGCCGATCCTGATCATCATCCTGCTGACGATCGGCGGCATTTACTCG
GGCATCTTCTCTCCCGTGGAAGCCGCCGCCGTGGGCGCCGGCCTGACGATCCTGTTCGGTGCCGCCATGCGCAAGCTGAC
CCTGGCTTCCTTCTGGCGGGCGGCACAAAGCTCCATCACCACCACGGCGACCGTGATGCTGATTCTGATCGCCGCGCACA
TGCTCAACCCCTTTCTGGCCTTGAGCCATATCCCGCAGGCCCTGGGCGATTTCCTGATGGCTCTGGATATCGGGCCGTAT
GGCGTCCTGCTGTTGATACTGGCCTGCTACCTGGTGCTGGGCTGCTTCCTGGAAGGGTTCGCGATGCTGGTGCTGACCAT
GCCGATCTTCTTCCCGGTCATCACCCAGCTGGGTTTCGATCCCATCTGGTTCGGCGTGCTGGTGGTACTGACACTGGAAA
TGGGGCTCATCAGCCCGCCGGTGGGCGTGAACGTCTTCATCGTCAAGTCCGTGGCACCCAACGTGCCGCTGCGCGACATC
TTCAAGGGTGTCATGCCGTTCTGGCTGGTGATGATCGCGGCCATCGGGCTGTTGATCGTCTTTCCCGATATCGTGCTGTT
TCTTCCCGATACGATGATGGACTAG

Upstream 100 bases:

>100_bases
TCTTTGCCTTCTTGACGGCACTTTCCATGCTGGCGCGCATCGTTTCGACGTCATTGACGTCATCCCACCGGCACGCGTCT
TTGCAAAAGGAAGAGGACTT

Downstream 100 bases:

>100_bases
GTGCCATGCGTCAGGTGGGCGCCGGTCCCGCTATGCCGATACCGGGTGCGGTATCGGCCCATTCTCAGCAGGAGAGGTCG
AAGATGGCTAATAATCGTGG

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSTELVGALGILALLALLVLRIPVAFAIFVVGFGGITVLDSLNSALSLLASETFTIASNAELIVIPLFILMGNIATEAGM
SRKLYDAAYALIGSVRGGLASATVVGCAGFAALCGSSVASALTMGRVSLSEMERFNYSAKLSTGSVAAGGTLGILIPPST
GFVIYAILTQQSIGRLFLAGVLPGIMLCLLFVLLIMLLATIKPVLAPSGPKTSWREKQQGLLGAMPILIIILLTIGGIYS
GIFSPVEAAAVGAGLTILFGAAMRKLTLASFWRAAQSSITTTATVMLILIAAHMLNPFLALSHIPQALGDFLMALDIGPY
GVLLLILACYLVLGCFLEGFAMLVLTMPIFFPVITQLGFDPIWFGVLVVLTLEMGLISPPVGVNVFIVKSVAPNVPLRDI
FKGVMPFWLVMIAAIGLLIVFPDIVLFLPDTMMD

Sequences:

>Translated_434_residues
MSTELVGALGILALLALLVLRIPVAFAIFVVGFGGITVLDSLNSALSLLASETFTIASNAELIVIPLFILMGNIATEAGM
SRKLYDAAYALIGSVRGGLASATVVGCAGFAALCGSSVASALTMGRVSLSEMERFNYSAKLSTGSVAAGGTLGILIPPST
GFVIYAILTQQSIGRLFLAGVLPGIMLCLLFVLLIMLLATIKPVLAPSGPKTSWREKQQGLLGAMPILIIILLTIGGIYS
GIFSPVEAAAVGAGLTILFGAAMRKLTLASFWRAAQSSITTTATVMLILIAAHMLNPFLALSHIPQALGDFLMALDIGPY
GVLLLILACYLVLGCFLEGFAMLVLTMPIFFPVITQLGFDPIWFGVLVVLTLEMGLISPPVGVNVFIVKSVAPNVPLRDI
FKGVMPFWLVMIAAIGLLIVFPDIVLFLPDTMMD
>Mature_433_residues
STELVGALGILALLALLVLRIPVAFAIFVVGFGGITVLDSLNSALSLLASETFTIASNAELIVIPLFILMGNIATEAGMS
RKLYDAAYALIGSVRGGLASATVVGCAGFAALCGSSVASALTMGRVSLSEMERFNYSAKLSTGSVAAGGTLGILIPPSTG
FVIYAILTQQSIGRLFLAGVLPGIMLCLLFVLLIMLLATIKPVLAPSGPKTSWREKQQGLLGAMPILIIILLTIGGIYSG
IFSPVEAAAVGAGLTILFGAAMRKLTLASFWRAAQSSITTTATVMLILIAAHMLNPFLALSHIPQALGDFLMALDIGPYG
VLLLILACYLVLGCFLEGFAMLVLTMPIFFPVITQLGFDPIWFGVLVVLTLEMGLISPPVGVNVFIVKSVAPNVPLRDIF
KGVMPFWLVMIAAIGLLIVFPDIVLFLPDTMMD

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=414, Percent_Identity=28.0193236714976, Blast_Score=148, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 45484; Mature: 45353

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTELVGALGILALLALLVLRIPVAFAIFVVGFGGITVLDSLNSALSLLASETFTIASNA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCC
ELIVIPLFILMGNIATEAGMSRKLYDAAYALIGSVRGGLASATVVGCAGFAALCGSSVAS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALTMGRVSLSEMERFNYSAKLSTGSVAAGGTLGILIPPSTGFVIYAILTQQSIGRLFLAG
HHHHHHHHHHHHHHHCCCEECCCCCEECCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
VLPGIMLCLLFVLLIMLLATIKPVLAPSGPKTSWREKQQGLLGAMPILIIILLTIGGIYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIFSPVEAAAVGAGLTILFGAAMRKLTLASFWRAAQSSITTTATVMLILIAAHMLNPFLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHIPQALGDFLMALDIGPYGVLLLILACYLVLGCFLEGFAMLVLTMPIFFPVITQLGFD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIWFGVLVVLTLEMGLISPPVGVNVFIVKSVAPNVPLRDIFKGVMPFWLVMIAAIGLLIV
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FPDIVLFLPDTMMD
HHHHHHHCCHHHCC
>Mature Secondary Structure 
STELVGALGILALLALLVLRIPVAFAIFVVGFGGITVLDSLNSALSLLASETFTIASNA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCC
ELIVIPLFILMGNIATEAGMSRKLYDAAYALIGSVRGGLASATVVGCAGFAALCGSSVAS
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ALTMGRVSLSEMERFNYSAKLSTGSVAAGGTLGILIPPSTGFVIYAILTQQSIGRLFLAG
HHHHHHHHHHHHHHHCCCEECCCCCEECCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHH
VLPGIMLCLLFVLLIMLLATIKPVLAPSGPKTSWREKQQGLLGAMPILIIILLTIGGIYS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHH
GIFSPVEAAAVGAGLTILFGAAMRKLTLASFWRAAQSSITTTATVMLILIAAHMLNPFLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSHIPQALGDFLMALDIGPYGVLLLILACYLVLGCFLEGFAMLVLTMPIFFPVITQLGFD
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIWFGVLVVLTLEMGLISPPVGVNVFIVKSVAPNVPLRDIFKGVMPFWLVMIAAIGLLIV
HHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FPDIVLFLPDTMMD
HHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]